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Nel Andre

Title(s)Director and PI NSF/EPA-funded Center for Environmental Implications of Nanotechnology, California NanoSystems Institute
SchoolCalifornia NanoSystems Institute
Phone(310) 206-8107
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    Other Positions
    Title(s)Professor, Medicine

    Title(s)Division Chief, NanoMedicine


    Collapse Research 
    Collapse Research Activities and Funding
    Toxicological Profiling of Engineered Nanomaterials (ENMs) in the MPS (RES)
    NIH/NIEHS U01ES027237Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    UCLA Multifunctional Mesoporous Silica Nanoparticle Platform for Treatment of Pancreas Cancer
    NIH/NCI U01CA198846Sep 25, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Carbon Nanotube Structure-Activity Relationships for Predictive Toxicology
    NIH/NIEHS R01ES022698Dec 9, 2013 - Oct 31, 2018
    Role: Principal Investigator
    Center for Nanobiology and Predictive Toxicology
    NIH/NIEHS U19ES019528Sep 24, 2010 - Apr 30, 2015
    Role: Principal Investigator
    Nanovalve Platform: Targeted, Controlled, Release of Anticancer Drugs
    NIH/NCI R01CA133697Jan 1, 2010 - Jun 30, 2015
    Role: Co-Principal Investigator
    Predictive Toxicological Paradigms to Establish Inhalation Toxicology Models
    NIH/NIEHS RC2ES018766Sep 30, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Predictive Toxicological Paradigm for Chronic Nanoparticle Injury in the Lung
    NIH/NIEHS R01ES016746May 15, 2008 - Mar 31, 2018
    Role: Principal Investigator
    Development of methods and models for nanoparticle toxicity screening: Applicatio
    NIH/NIEHS R01ES015498Sep 30, 2006 - Jun 30, 2009
    Role: Principal Investigator
    Xenobiotics, Oxidative Stress and Allergic Inflammation
    NIH/NIAID U19AI070453Jul 15, 2006 - Jun 30, 2012
    Role: Principal Investigator
    Atherogenic Effects of Ambient PM In Susceptible Animals
    NIH/NIEHS R01ES013432Sep 1, 2004 - Jul 31, 2010
    Role: Principal Investigator
    Proteomics of DEP-induced Oxidative Stress
    NIH/NIEHS R01ES012053Sep 10, 2002 - Jul 31, 2008
    Role: Principal Investigator
    Biological Analysis of Toxic DEP Chemicals
    NIH/NIEHS R01ES010553Feb 21, 2002 - Nov 30, 2008
    Role: Principal Investigator
    Lipids rafts in JNK and Nk-kB activation by TCR/CD28
    NIH/NIA R01AG014992Aug 1, 1998 - Apr 30, 2010
    Role: Principal Investigator
    MAPK CASCADES AND FUNCTION DECLINE OF AGED T CELLS
    NIH/NIA R03AG014763Aug 1, 1997 - Jul 31, 1999
    Role: Principal Investigator
    CYTOKINE AND GROWTH FACTOR PATHWAYS IN KAPOSIS SARCOMA
    NIH/NCI R01CA065329Jul 1, 1994 - Apr 30, 2000
    Role: Principal Investigator
    PKC AND TYROSINE KINASES SYNERGIZE IN T-CELL ACTIVATION
    NIH/NIGMS R01GM041576Sep 1, 1988 - Mar 31, 1997
    Role: Principal Investigator
    ALLERGY, IMMUNOLOGY &TRANSPLANTATION RESEARCH COMMITTEE
    NIH/NIAID U09AI023260Jul 1, 1985 - Jun 30, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Khademhosseini A, Nel AE, Bunje H, DeSantis CJ, Andrews AM, Blaik RA, Gu Z, Meng H, Ozcan A, Tolbert SH, Xia T, Zink JI, Weiss PS. Nanoscience and Nanotechnology at UCLA. ACS Nano. 2019 Jun 25; 13(6):6127-6129. PMID: 31247733.
      View in: PubMed
    2. Pooran A, Davids M, Nel A, Shoko A, Blackburn J, Dheda K. IL-4 subverts mycobacterial containment in M. tuberculosis-infected human macrophages. Eur Respir J. 2019 May 16. PMID: 31097521.
      View in: PubMed
    3. Liu Q, Wang X, Liu X, Kumar S, Gochman G, Ji Y, Liao YP, Chang CH, Situ W, Lu J, Jiang J, Mei KC, Meng H, Xia T, Nel AE. Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model. ACS Nano. 2019 Apr 23; 13(4):4778-4794. PMID: 30964276.
      View in: PubMed
    4. Poole JA, Barnes CS, Demain JG, Bernstein JA, Padukudru MA, Sheehan WJ, Fogelbach GG, Wedner J, Codina R, Levetin E, Cohn JR, Kagen S, Portnoy JM, Nel AE. Impact of weather and climate change with indoor and outdoor air quality in asthma: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee. J Allergy Clin Immunol. 2019 May; 143(5):1702-1710. PMID: 30826366.
      View in: PubMed
    5. Liu X, Jiang J, Chan R, Ji Y, Lu J, Liao YP, Okene M, Lin J, Lin P, Chang CH, Wang X, Tang I, Zheng E, Qiu W, Wainberg ZA, Nel AE, Meng H. Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer. ACS Nano. 2019 Jan 22; 13(1):38-53. PMID: 30525443.
      View in: PubMed
    6. Lu J, Liu X, Liao YP, Wang X, Ahmed A, Jiang W, Ji Y, Meng H, Nel AE. Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway. ACS Nano. 2018 Nov 27; 12(11):11041-11061. PMID: 30481959.
      View in: PubMed
    7. Meng H, Nel AE. Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer. Adv Drug Deliv Rev. 2018 May; 130:50-57. PMID: 29958925.
      View in: PubMed
    8. Parak WJ, Chan WWC, Chhowalla M, Farokhzad O, Glotzer S, Gogotsi Y, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Lee YH, Li Y, Millstone J, Mulvaney PA, Nel AE, Nordlander PJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Weiss PS. Helmuth Möhwald (1946-2018). ACS Nano. 2018 Apr 24; 12(4):3053-3055. PMID: 29676563.
      View in: PubMed
    9. Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. ACS Nano. 2018 02 27; 12(2):1390-1402. PMID: 29328670.
      View in: PubMed
    10. Chan WWC, Chhowalla M, Farokhzad O, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Li Y, Millstone J, Möhwald H, Mulvaney PC, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Fernandez LE, Weiss PS. A Big Year Ahead for Nano in 2018. ACS Nano. 2017 12 26; 11(12):11755-11757. PMID: 29294604.
      View in: PubMed
    11. Hartshorn CM, Bradbury MS, Lanza GM, Nel AE, Rao J, Wang AZ, Wiesner UB, Yang L, Grodzinski P. Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care. ACS Nano. 2018 01 23; 12(1):24-43. PMID: 29257865.
      View in: PubMed
    12. Lu J, Liu X, Liao YP, Salazar F, Sun B, Jiang W, Chang CH, Jiang J, Wang X, Wu AM, Meng H, Nel AE. Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression. Nat Commun. 2017 11 27; 8(1):1811. PMID: 29180759.
      View in: PubMed
    13. Chan WCW, Chhowalla M, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney P, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Fernandez LE, Weiss PS. Our First and Next Decades at ACS Nano. ACS Nano. 2017 08 22; 11(8):7553-7555. PMID: 28830059.
      View in: PubMed
    14. Liu X, Jiang J, Nel AE, Meng H. Major effect of transcytosis on nano drug delivery to pancreatic cancer. Mol Cell Oncol. 2017; 4(4):e1335273. PMID: 28868347.
      View in: PubMed
    15. Malloy T, Zaunbrecher V, Beryt E, Judson R, Tice R, Allard P, Blake A, Cote I, Godwin H, Heine L, Kerzic P, Kostal J, Marchant G, McPartland J, Moran K, Nel A, Ogunseitan O, Rossi M, Thayer K, Tickner J, Whittaker M, Zarker K. Advancing alternatives analysis: The role of predictive toxicology in selecting safer chemical products and processes. Integr Environ Assess Manag. 2017 Sep; 13(5):915-925. PMID: 28247928.
      View in: PubMed
    16. Liu X, Lin P, Perrett I, Lin J, Liao YP, Chang CH, Jiang J, Wu N, Donahue T, Wainberg Z, Nel AE, Meng H. Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer. J Clin Invest. 2017 May 01; 127(5):2007-2018. PMID: 28414297.
      View in: PubMed
    17. Pelaz B, Alexiou C, Alvarez-Puebla RA, Alves F, Andrews AM, Ashraf S, Balogh LP, Ballerini L, Bestetti A, Brendel C, Bosi S, Carril M, Chan WC, Chen C, Chen X, Chen X, Cheng Z, Cui D, Du J, Dullin C, Escudero A, Feliu N, Gao M, George M, Gogotsi Y, Grünweller A, Gu Z, Halas NJ, Hampp N, Hartmann RK, Hersam MC, Hunziker P, Jian J, Jiang X, Jungebluth P, Kadhiresan P, Kataoka K, Khademhosseini A, Kopecek J, Kotov NA, Krug HF, Lee DS, Lehr CM, Leong KW, Liang XJ, Ling Lim M, Liz-Marzán LM, Ma X, Macchiarini P, Meng H, Möhwald H, Mulvaney P, Nel AE, Nie S, Nordlander P, Okano T, Oliveira J, Park TH, Penner RM, Prato M, Puntes V, Rotello VM, Samarakoon A, Schaak RE, Shen Y, Sjöqvist S, Skirtach AG, Soliman MG, Stevens MM, Sung HW, Tang BZ, Tietze R, Udugama BN, VanEpps JS, Weil T, Weiss PS, Willner I, Wu Y, Yang L, Yue Z, Zhang Q, Zhang Q, Zhang XE, Zhao Y, Zhou X, Parak WJ. Diverse Applications of Nanomedicine. ACS Nano. 2017 03 28; 11(3):2313-2381. PMID: 28290206.
      View in: PubMed
    18. Nel AE, Malloy TF. Policy reforms to update chemical safety testing. Science. 2017 Mar 10; 355(6329):1016-1018. PMID: 28280165.
      View in: PubMed
    19. Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad O, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS. Nanoscience and Nanotechnology Cross Borders. ACS Nano. 2017 02 28; 11(2):1123-1126. PMID: 28199099.
      View in: PubMed
    20. Naatz H, Lin S, Li R, Jiang W, Ji Z, Chang CH, Köser J, Thöming J, Xia T, Nel AE, Mädler L, Pokhrel S. Safe-by-Design CuO Nanoparticles via Fe-Doping, Cu-O Bond Length Variation, and Biological Assessment in Cells and Zebrafish Embryos. ACS Nano. 2017 01 24; 11(1):501-515. PMID: 28026936.
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    21. Chan WW, Chhowalla M, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Fernandez LE, Weiss PS. Nanoscience and Nanotechnology Impacting Diverse Fields of Science, Engineering, and Medicine. ACS Nano. 2016 12 27; 10(12):10615-10617. PMID: 28024354.
      View in: PubMed
    22. Li R, Mansukhani ND, Guiney LM, Ji Z, Zhao Y, Chang CH, French CT, Miller JF, Hersam MC, Nel AE, Xia T. Identification and Optimization of Carbon Radicals on Hydrated Graphene Oxide for Ubiquitous Antibacterial Coatings. ACS Nano. 2016 12 27; 10(12):10966-10980. PMID: 28024366.
      View in: PubMed
    23. Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. Correction to Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice. ACS Nano. 2016 06 28; 10(6):6416. PMID: 27199284.
      View in: PubMed
    24. Liu X, Situ A, Kang Y, Villabroza KR, Liao Y, Chang CH, Donahue T, Nel AE, Meng H. Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer. ACS Nano. 2016 Feb 23; 10(2):2702-15. PMID: 26835979; PMCID: PMC4851343 [Available on 02/23/17].
    25. Chan WW, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Tierney HL, Weiss PS. Grand Plans for Nano. ACS Nano. 2015 Dec 22; 9(12):11503-5. PMID: 26689337.
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    26. Hersam MC, Lee ST, Nel AE, Rogach A, Buriak JM, Weiss PS. Big Roles for Nanocenters. ACS Nano. 2015 Sep 22; 9(9):8639-40. PMID: 26391441.
      View in: PubMed
    27. Liu R, Liu HH, Ji Z, Chang CH, Xia T, Nel AE, Cohen Y. Evaluation of Toxicity Ranking for Metal Oxide Nanoparticles via an in Vitro Dosimetry Model. ACS Nano. 2015 Sep 22; 9(9):9303-13. PMID: 26284985.
      View in: PubMed
    28. Parak WJ, Nel AE, Weiss PS. Grand Challenges for Nanoscience and Nanotechnology. ACS Nano. 2015 Jul 28; 9(7):6637-40. PMID: 26192457.
      View in: PubMed
    29. Kaweeteerawat C, Chang CH, Roy KR, Liu R, Li R, Toso D, Fischer H, Ivask A, Ji Z, Zink JI, Zhou ZH, Chanfreau GF, Telesca D, Cohen Y, Holden PA, Nel AE, Godwin HA. Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues. ACS Nano. 2015 Jul 28; 9(7):7215-25. PMID: 26168153.
      View in: PubMed
    30. Nel AE, Parak WJ, Chan WC, Xia T, Hersam MC, Brinker CJ, Zink JI, Pinkerton KE, Baer DR, Weiss PS. Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization? ACS Nano. 2015 Jun 23; 9(6):5627-30. PMID: 26100220.
      View in: PubMed
    31. Zhang H, Wang X, Wang M, Li L, Chang CH, Ji Z, Xia T, Nel AE. Mammalian Cells Exhibit a Range of Sensitivities to Silver Nanoparticles that are Partially Explicable by Variations in Antioxidant Defense and Metallothionein Expression. Small. 2015 Aug; 11(31):3797-805. PMID: 25930061.
      View in: PubMed
    32. Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice. ACS Nano. 2015; 9(4):3540-57. PMID: 25776964.
      View in: PubMed
    33. Godwin H, Nameth C, Avery D, Bergeson LL, Bernard D, Beryt E, Boyes W, Brown S, Clippinger AJ, Cohen Y, Doa M, Hendren CO, Holden P, Houck K, Kane AB, Klaessig F, Kodas T, Landsiedel R, Lynch I, Malloy T, Miller MB, Muller J, Oberdorster G, Petersen EJ, Pleus RC, Sayre P, Stone V, Sullivan KM, Tentschert J, Wallis P, Nel AE. Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making. ACS Nano. 2015; 9(4):3409-17. PMID: 25791861.
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    34. Li R, Ji Z, Dong J, Chang CH, Wang X, Sun B, Wang M, Liao YP, Zink JI, Nel AE, Xia T. Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating. ACS Nano. 2015 Mar 24; 9(3):3293-306. PMID: 25727446; PMCID: PMC4415359.
    35. Chan WC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Weiss PS. A year for nanoscience. ACS Nano. 2014 Dec 23; 8(12):11901-3. PMID: 25533169.
      View in: PubMed
    36. Li R, Ji Z, Qin H, Kang X, Sun B, Wang M, Chang CH, Wang X, Zhang H, Zou H, Nel AE, Xia T. Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1ß producing inflammasome. ACS Nano. 2014 Oct 28; 8(10):10280-92. PMID: 25251502.
      View in: PubMed
    37. Liu R, France B, George S, Rallo R, Zhang H, Xia T, Nel AE, Bradley K, Cohen Y. Association rule mining of cellular responses induced by metal and metal oxide nanoparticles. Analyst. 2014 Mar 07; 139(5):943-53. PMID: 24260774.
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    38. Li R, Ji Z, Chang CH, Dunphy DR, Cai X, Meng H, Zhang H, Sun B, Wang X, Dong J, Lin S, Wang M, Liao YP, Brinker CJ, Nel A, Xia T. Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design. ACS Nano. 2014 Feb 25; 8(2):1771-83. PMID: 24417322.
      View in: PubMed
    39. Heber D, Li Z, Garcia-Lloret M, Wong AM, Lee TY, Thames G, Krak M, Zhang Y, Nel A. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014 Jan; 5(1):35-41. PMID: 24287881.
      View in: PubMed
    40. Meng H, Zhao Y, Dong J, Xue M, Lin YS, Ji Z, Mai WX, Zhang H, Chang CH, Brinker CJ, Zink JI, Nel AE. Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice. ACS Nano. 2013 Nov 26; 7(11):10048-65. PMID: 24143858; PMCID: PMC3878438.
    41. Parak WJ, Chan WC, Hafner JH, Hammond PT, Hersam MC, Javey A, Khademhosseini A, Kotov NA, Mulvaney P, Nel AE, Nordlander PJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Weiss PS. Be critical but fair. ACS Nano. 2013 Oct 22; 7(10):8313-6. PMID: 24143923.
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    42. Mulvaney P, Nel AE, Rogach A, Weiss PS. Nanocenter directors gather from around the world. ACS Nano. 2013 Sep 24; 7(9):7437-8. PMID: 24490873.
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    43. Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, Kuempel E, Lafranconi M, Landsiedel R, Malloy T, Miller MB, Morris J, Moss K, Oberdorster G, Pinkerton K, Pleus RC, Shatkin JA, Thomas R, Tolaymat T, Wang A, Wong J. A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. ACS Nano. 2013 Aug 27; 7(8):6422-33. PMID: 23924032.
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    44. Liu R, Zhang HY, Ji ZX, Rallo R, Xia T, Chang CH, Nel A, Cohen Y. Development of structure-activity relationship for metal oxide nanoparticles. Nanoscale. 2013 Jun 21; 5(12):5644-53. PMID: 23689214.
      View in: PubMed
    45. Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, Vulpe CD, Walker AJ, Wang X, Witzmann FA, Wu N, Xie Y, Zink JI, Nel A, Holian A. Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect. 2013 Jun; 121(6):683-90. PMID: 23649538; PMCID: PMC3672931.
    46. Li N, Wang M, Barajas B, Sioutas C, Williams MA, Nel AE. Nrf2 deficiency in dendritic cells enhances the adjuvant effect of ambient ultrafine particles on allergic sensitization. J Innate Immun. 2013; 5(6):543-54. PMID: 23595026.
      View in: PubMed
    47. Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. ACS Nano. 2013 Feb 26; 7(2):994-1005. PMID: 23289892; PMCID: PMC3620006.
    48. Jiang S, Cheng R, Wang X, Xue T, Liu Y, Nel A, Huang Y, Duan X. Real-time electrical detection of nitric oxide in biological systems with sub-nanomolar sensitivity. Nat Commun. 2013; 4:2225. PMID: 23887829.
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    49. Bonnell DA, Buriak JM, Chan WC, Hafner JH, Hammond PT, Hersam MC, Javey A, Kotov NA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Weiss PS. We take it personally. ACS Nano. 2012 Dec 21; 6(12):10417-9. PMID: 23256549.
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    50. Xia T, Malasarn D, Lin S, Ji Z, Zhang H, Miller RJ, Keller AA, Nisbet RM, Harthorn BH, Godwin HA, Lenihan HS, Liu R, Gardea-Torresdey J, Cohen Y, Mädler L, Holden PA, Zink JI, Nel AE. Implementation of a multidisciplinary approach to solve complex nano EHS problems by the UC Center for the Environmental Implications of Nanotechnology. Small. 2013 May 27; 9(9-10):1428-43. PMID: 23027589.
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    51. Zhang H, Dunphy DR, Jiang X, Meng H, Sun B, Tarn D, Xue M, Wang X, Lin S, Ji Z, Li R, Garcia FL, Yang J, Kirk ML, Xia T, Zink JI, Nel A, Brinker CJ. Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic. J Am Chem Soc. 2012 Sep 26; 134(38):15790-804. PMID: 22924492; PMCID: PMC3505689.
    52. Nel A, Xia T, Meng H, Wang X, Lin S, Ji Z, Zhang H. Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Acc Chem Res. 2013 Mar 19; 46(3):607-21. PMID: 22676423.
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    53. Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE. Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano. 2012 May 22; 6(5):4349-68. PMID: 22502734; PMCID: PMC4139054.
    54. Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y. Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PLoS One. 2012; 7(4):e35014. PMID: 22506062; PMCID: PMC3323610.
    55. Clemens DL, Lee BY, Xue M, Thomas CR, Meng H, Ferris D, Nel AE, Zink JI, Horwitz MA. Targeted intracellular delivery of antituberculosis drugs to Mycobacterium tuberculosis-infected macrophages via functionalized mesoporous silica nanoparticles. Antimicrob Agents Chemother. 2012 May; 56(5):2535-45. PMID: 22354311; PMCID: PMC3346638.
    56. Meng H, Xue M, Zink JI, Nel AE. Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles Platform. J Phys Chem Lett. 2012 Feb 02; 3(3):358-9. PMID: 26285851.
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    57. Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE. High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS Nano. 2011 Sep 27; 5(9):7284-95. PMID: 21851096.
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    58. Li N, Nel AE. Feasibility of biomarker studies for engineered nanoparticles: what can be learned from air pollution research. J Occup Environ Med. 2011 Jun; 53(6 Suppl):S74-9. PMID: 21654422.
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    59. Meng H, Yang S, Li Z, Xia T, Chen J, Ji Z, Zhang H, Wang X, Lin S, Huang C, Zhou ZH, Zink JI, Nel AE. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. ACS Nano. 2011 Jun 28; 5(6):4434-47. PMID: 21563770.
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    60. Meng H, Xue M, Xia T, Ji Z, Tarn DY, Zink JI, Nel AE. Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica nanoparticles in a murine xenograft tumor model. ACS Nano. 2011 May 24; 5(5):4131-44. PMID: 21524062; PMCID: PMC3905975.
    61. Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, Nel AE. Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. ACS Nano. 2011 Apr 26; 5(4):2756-2769. PMID: 21366263; PMCID: PMC3896548.
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    110. Li N, Hao M, Phalen RF, Hinds WC, Nel AE. Particulate air pollutants and asthma. A paradigm for the role of oxidative stress in PM-induced adverse health effects. Clin Immunol. 2003 Dec; 109(3):250-65. PMID: 14697739.
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    113. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect. 2003 Apr; 111(4):455-60. PMID: 12676598.
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    114. Li N, Wang M, Oberley TD, Sempf JM, Nel AE. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J Immunol. 2002 Oct 15; 169(8):4531-41. PMID: 12370390.
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    115. Zhang K, Zhang L, Zhu D, Bae D, Nel A, Saxon A. CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE. J Allergy Clin Immunol. 2002 Sep; 110(3):421-8. PMID: 12209089.
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    116. Nel AE, Slaughter N. T-cell activation through the antigen receptor. Part 2: role of signaling cascades in T-cell differentiation, anergy, immune senescence, and development of immunotherapy. J Allergy Clin Immunol. 2002 Jun; 109(6):901-15. PMID: 12063516.
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    119. Whitekus MJ, Li N, Zhang M, Wang M, Horwitz MA, Nelson SK, Horwitz LD, Brechun N, Diaz-Sanchez D, Nel AE. Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. J Immunol. 2002 Mar 01; 168(5):2560-7. PMID: 11859152.
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    120. Yuan J, Bae D, Cantrell D, Nel AE, Rozengurt E. Protein kinase D is a downstream target of protein kinase Ctheta. Biochem Biophys Res Commun. 2002 Mar 01; 291(3):444-52. PMID: 11855809.
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