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Spiegel Brennan

Title(s)Member, CTSI
SchoolCTSI
Phone310.268.4510
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    Other Positions
    Title(s)Director, Center for Outcomes Research and Education (CORE)

    Title(s)Professor In-Residence, Fielding School of Public Health

    Title(s)Professor In-Residence, Medicine

    Title(s)Professor, Health Policy and Management


    Collapse Research 
    Collapse Research Activities and Funding
    Development and Initial Validation of PROMIS GI Distress Scale
    NIH/NIAMS U01AR057936Sep 30, 2009 - Jun 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sarma KV, Spiegel BMR, Reid MW, Chen S, Merchant RM, Seltzer E, Arnold CW. Estimating the Health-Related Quality of Life of Twitter Users Using Semantic Processing. Stud Health Technol Inform. 2019 Aug 21; 264:1065-1069. PMID: 31438088.
      View in: PubMed
    2. Spiegel B, Fuller G, Lopez M, Dupuy T, Noah B, Howard A, Albert M, Tashjian V, Lam R, Ahn J, Dailey F, Rosen BT, Vrahas M, Little M, Garlich J, Dzubur E, IsHak W, Danovitch I. Virtual reality for management of pain in hospitalized patients: A randomized comparative effectiveness trial. PLoS One. 2019; 14(8):e0219115. PMID: 31412029.
      View in: PubMed
    3. Lacy BE, Spiegel B. Introduction to the Gut Microbiome Special Issue. Am J Gastroenterol. 2019 Jul; 114(7):1013. PMID: 31205134.
      View in: PubMed
    4. Gu P, Lew D, Oh SJ, Vipani A, Ko J, Hsu K, Mirakhor E, Pattisapu V, Bullen T, Fuller G, Spiegel BMR, Almario CV. Comparing the Real-World Effectiveness of Competing Colonoscopy Preparations: Results of a Prospective Trial. Am J Gastroenterol. 2019 Feb; 114(2):305-314. PMID: 30730859.
      View in: PubMed
    5. Daskivich TJ, Houman J, Lopez M, Luu M, Fleshner P, Zaghiyan K, Cunneen S, Burch M, Walsh C, Paiement G, Kremen T, Soukiasian H, Spitzer A, Jackson T, Kim HL, Li A, Spiegel B. Association of Wearable Activity Monitors With Assessment of Daily Ambulation and Length of Stay Among Patients Undergoing Major Surgery. JAMA Netw Open. 2019 Feb 01; 2(2):e187673. PMID: 30707226.
      View in: PubMed
    6. Dzubur E, Khalil C, Almario CV, Noah B, Minhas D, Ishimori M, Arnold C, Park Y, Kay J, Weisman MH, Spiegel BMR. Patient Concerns and Perceptions Regarding Biologic Therapies in Ankylosing Spondylitis: Insights From a Large-Scale Survey of Social Media Platforms. Arthritis Care Res (Hoboken). 2019 Feb; 71(2):323-330. PMID: 29781587.
      View in: PubMed
    7. Birckhead B, Khalil C, Liu X, Conovitz S, Rizzo A, Danovitch I, Bullock K, Spiegel B. Recommendations for Methodology of Virtual Reality Clinical Trials in Health Care by an International Working Group: Iterative Study. JMIR Ment Health. 2019 Jan 31; 6(1):e11973. PMID: 30702436.
      View in: PubMed
    8. Lacy BE, Spiegel B. Introduction to the 80% by 2018 Special Issue. Am J Gastroenterol. 2018 Dec; 113(12):1737-1738. PMID: 30377308.
      View in: PubMed
    9. Almario CV, Ballal ML, Chey WD, Nordstrom C, Khanna D, Spiegel BMR. Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans. Am J Gastroenterol. 2018 Nov; 113(11):1701-1710. PMID: 30323268.
      View in: PubMed
    10. Speier W, Dzubur E, Zide M, Shufelt C, Joung S, Van Eyk JE, Bairey Merz CN, Lopez M, Spiegel B, Arnold C. Evaluating utility and compliance in a patient-based eHealth study using continuous-time heart rate and activity trackers. J Am Med Inform Assoc. 2018 Oct 01; 25(10):1386-1391. PMID: 29850807.
      View in: PubMed
    11. Almario CV, Chen MS, Spiegel BMR. Reply to Johnson et al. Regarding Optimizing Selection of Biologics in Inflammatory Bowel Disease: Development of an Online Patient Decision Aid Using Conjoint Analysis. Am J Gastroenterol. 2018 Nov; 113(11):1721. PMID: 30214014.
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    12. Delshad SD, Almario CV, Fuller G, Luong D, Spiegel BMR. Erratum: Author Correction: Economic analysis of implementing virtual reality therapy for pain among hospitalized patients. NPJ Digit Med. 2018; 1:41. PMID: 31305585.
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    13. Fuller G, Green J, Litt Deculus C, Black J, Weingarten S, Ramirez G, Spiegel B. Validity of Physician and Administrator Peer Review for Selecting Specialist Narrow Network Participants. Popul Health Manag. 2019 Apr; 22(2):169-174. PMID: 30070963.
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    14. Gresham G, Hendifar AE, Spiegel B, Neeman E, Tuli R, Rimel BJ, Figlin RA, Meinert CL, Piantadosi S, Shinde AM. Wearable activity monitors to assess performance status and predict clinical outcomes in advanced cancer patients. NPJ Digit Med. 2018; 1:27. PMID: 31304309.
      View in: PubMed
    15. Delshad SD, Almario CV, Fuller G, Luong D, Spiegel BMR. Economic analysis of implementing virtual reality therapy for pain among hospitalized patients. NPJ Digit Med. 2018; 1:22. PMID: 31304304.
      View in: PubMed
    16. Keller MS, Mosadeghi S, Cohen ER, Kwan J, Spiegel BMR. Reproductive Health and Medication Concerns for Patients With Inflammatory Bowel Disease: Thematic and Quantitative Analysis Using Social Listening. J Med Internet Res. 2018 Jun 11; 20(6):e206. PMID: 29891471.
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    17. Daskivich TJ, Spiegel B. Response to Letter to the Editor. J Am Med Inform Assoc. 2018 Jun 01; 25(6):745. PMID: 29237028.
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    18. Spiegel BM. Virtual medicine: how virtual reality is easing pain, calming nerves and improving health. Med J Aust. 2018 Sep 17; 209(6):245-247. PMID: 29764343.
      View in: PubMed
    19. Daskivich T, Luu M, Noah B, Fuller G, Anger J, Spiegel B. Differences in Online Consumer Ratings of Health Care Providers Across Medical, Surgical, and Allied Health Specialties: Observational Study of 212,933 Providers. J Med Internet Res. 2018 May 09; 20(5):e176. PMID: 29743150.
      View in: PubMed
    20. Nangit A, Lin C, Ishimori ML, Spiegel BMR, Weisman MH. Causes and Predictors of Early Hospital Readmission in Systemic Lupus Erythematosus. J Rheumatol. 2018 Jul; 45(7):929-933. PMID: 29657150.
      View in: PubMed
    21. Noah B, Keller MS, Mosadeghi S, Stein L, Johl S, Delshad S, Tashjian VC, Lew D, Kwan JT, Jusufagic A, Spiegel BMR. Erratum: Author Correction: Impact of remote patient monitoring on clinical outcomes: an updated meta-analysis of randomized controlled trials. NPJ Digit Med. 2018; 1:17. PMID: 31305588.
      View in: PubMed
    22. Almario CV, Spiegel BMR. Employing Irritable Bowel Syndrome Patient-Reported Outcomes in the Clinical Trenches. Clin Gastroenterol Hepatol. 2018 Apr; 16(4):462-466.e2. PMID: 29555225.
      View in: PubMed
    23. Daskivich TJ, Houman J, Fuller G, Black JT, Kim HL, Spiegel B. Online physician ratings fail to predict actual performance on measures of quality, value, and peer review. J Am Med Inform Assoc. 2018 04 01; 25(4):401-407. PMID: 29025145.
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    24. Almario CV, Noah BD, Jusufagic A, Lew D, Spiegel BMR. Cost Effectiveness of Biomarker Tests for Irritable Bowel Syndrome With Diarrhea: A Framework for Payers. Clin Gastroenterol Hepatol. 2018 Sep; 16(9):1434-1441.e21. PMID: 29596984.
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    25. Ahmed S, Almario CV, Chey WD, Robbins LA, Chang B, Ahn J, Ko J, Gu P, Siu A, Spiegel BMR. Electronic patient agenda forms: comparing agreement between the reason for specialty consultation reported by referring providers and patients. Inform Health Soc Care. 2019 Jan; 44(1):105-113. PMID: 29509054.
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    26. Asanad K, Parameshwar PS, Houman J, Spiegel BM, Daskivich TJ, Anger JT. Online Physician Reviews in Female Pelvic Medicine and Reconstructive Surgery: What Do Patients Really Want? Female Pelvic Med Reconstr Surg. 2018 Mar/Apr; 24(2):109-114. PMID: 29474282.
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    27. Menees SB, Almario CV, Spiegel BMR, Chey WD. Prevalence of and Factors Associated With Fecal Incontinence: Results From a Population-Based Survey. Gastroenterology. 2018 05; 154(6):1672-1681.e3. PMID: 29408460.
      View in: PubMed
    28. Noah B, Keller MS, Mosadeghi S, Stein L, Johl S, Delshad S, Tashjian VC, Lew D, Kwan JT, Jusufagic A, Spiegel BMR. Impact of remote patient monitoring on clinical outcomes: an updated meta-analysis of randomized controlled trials. NPJ Digit Med. 2018; 1:20172. PMID: 31304346.
      View in: PubMed
    29. Gu P, Kapur A, Li D, Haritunians T, Vasiliauskas E, Shih DQ, Targan SR, Spiegel BM, Mcgovern DP, Black JT, Melmed GY. Serological, genetic and clinical associations with increased health-care resource utilization in inflammatory bowel disease. J Dig Dis. 2018 Jan; 19(1):15-23. PMID: 29251413.
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    30. Daskivich TJ, Abedi G, Kaplan SH, Skarecky D, Ahlering T, Spiegel B, Litwin MS, Greenfield S. Electronic health record problem lists: accurate enough for risk adjustment? Am J Manag Care. 2018 Jan 01; 24(1):e24-e29. PMID: 29350512.
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    31. Keller MS, Park HJ, Cunningham ME, Fouladian JE, Chen M, Spiegel BMR. Public Perceptions Regarding Use of Virtual Reality in Health Care: A Social Media Content Analysis Using Facebook. J Med Internet Res. 2017 Dec 19; 19(12):e419. PMID: 29258975.
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    32. Spiegel B, Lacy B. Putting Patients First. Am J Gastroenterol. 2018 Jan; 113(1):1. PMID: 29231191.
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    33. Almario CV, Keller MS, Chen M, Lasch K, Ursos L, Shklovskaya J, Melmed GY, Spiegel BMR. Optimizing Selection of Biologics in Inflammatory Bowel Disease: Development of an Online Patient Decision Aid Using Conjoint Analysis. Am J Gastroenterol. 2018 Jan; 113(1):58-71. PMID: 29206816.
      View in: PubMed
    34. Lacy BE, Spiegel B. No Results? No Problem! Why We Are Publishing Methods of a Landmark Study With Results Still Pending. Am J Gastroenterol. 2017 Nov; 112(11):1747-1748. PMID: 29109496.
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    35. Kochar B, Martin CF, Kappelman MD, Spiegel BM, Chen W, Sandler RS, Long MD. Evaluation of Gastrointestinal Patient Reported Outcomes Measurement Information System (GI-PROMIS) Symptom Scales in Subjects With Inflammatory Bowel Diseases. Am J Gastroenterol. 2018 Jan; 113(1):72-79. PMID: 28853727.
      View in: PubMed
    36. Martinez B, Dailey F, Almario CV, Keller MS, Desai M, Dupuy T, Mosadeghi S, Whitman C, Lasch K, Ursos L, Spiegel BMR. Patient Understanding of the Risks and Benefits of Biologic Therapies in Inflammatory Bowel Disease: Insights from a Large-scale Analysis of Social Media Platforms. Inflamm Bowel Dis. 2017 07; 23(7):1057-1064. PMID: 28410343.
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    37. Tashjian VC, Mosadeghi S, Howard AR, Lopez M, Dupuy T, Reid M, Martinez B, Ahmed S, Dailey F, Robbins K, Rosen B, Fuller G, Danovitch I, IsHak W, Spiegel B. Virtual Reality for Management of Pain in Hospitalized Patients: Results of a Controlled Trial. JMIR Ment Health. 2017 Mar 29; 4(1):e9. PMID: 28356241.
      View in: PubMed
    38. Almario CV, Almario AA, Cunningham ME, Fouladian J, Spiegel BMR. Old Farts - Fact or Fiction? Results From a Population-Based Survey of 16,000 Americans Examining the Association Between Age and Flatus. Clin Gastroenterol Hepatol. 2017 Aug; 15(8):1308-1310. PMID: 28344066.
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    39. Khanna D, Hays RD, Shreiner AB, Melmed GY, Chang L, Khanna PP, Bolus R, Whitman C, Paz SH, Hays T, Reise SP, Spiegel B. Responsiveness to Change and Minimally Important Differences of the Patient-Reported Outcomes Measurement Information System Gastrointestinal Symptoms Scales. Dig Dis Sci. 2017 05; 62(5):1186-1192. PMID: 28251500.
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    40. Almario CV, Spiegel BM. Does endoscopist fatigue impact adenoma detection rate? A review of the evidence to date. Gastrointest Endosc. 2017 03; 85(3):611-613. PMID: 28215770.
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    41. Dascal J, Reid M, IsHak WW, Spiegel B, Recacho J, Rosen B, Danovitch I. Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials. Innov Clin Neurosci. 2017 Jan-Feb; 14(1-2):14-21. PMID: 28386517.
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    42. Fuller G, Bolus R, Whitman C, Talley J, Erder MH, Joseph A, Silberg DG, Spiegel B. PRISM, a Patient-Reported Outcome Instrument, Accurately Measures Symptom Change in Refractory Gastroesophageal Reflux Disease. Dig Dis Sci. 2017 03; 62(3):593-606. PMID: 28116591.
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    43. May FP, Glenn BA, Crespi CM, Ponce N, Spiegel BMR, Bastani R. Decreasing Black-White Disparities in Colorectal Cancer Incidence and Stage at Presentation in the United States. Cancer Epidemiol Biomarkers Prev. 2017 05; 26(5):762-768. PMID: 28035021.
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    44. Pevnick JM, Fuller G, Duncan R, Spiegel BM. A Large-Scale Initiative Inviting Patients to Share Personal Fitness Tracker Data with Their Providers: Initial Results. PLoS One. 2016; 11(11):e0165908. PMID: 27846287.
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    45. Siegel CA, Whitman CB, Spiegel BMR, Feagan B, Sands B, Loftus EV, Panaccione R, D'Haens G, Bernstein CN, Gearry R, Ng SC, Mantzaris GJ, Sartor B, Silverberg MS, Riddell R, Koutroubakis IE, O'Morain C, Lakatos PL, McGovern DPB, Halfvarson J, Reinisch W, Rogler G, Kruis W, Tysk C, Schreiber S, Danese S, Sandborn W, Griffiths A, Moum B, Gasche C, Pallone F, Travis S, Panes J, Colombel JF, Hanauer S, Peyrin-Biroulet L. Development of an index to define overall disease severity in IBD. Gut. 2018 02; 67(2):244-254. PMID: 27780886.
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    46. Kwan J, Stein L, Delshad S, Johl S, Park H, Martinez B, Topp L, Spiegel BM. Does "Decision Fatigue" Impact Manuscript Acceptance? An Analysis of Editorial Decisions by the American Journal of Gastroenterology. Am J Gastroenterol. 2016 Nov; 111(11):1511-1512. PMID: 27725653.
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    47. Spiegel B, Lacy BE. Negative Is Positive. Am J Gastroenterol. 2016 Nov; 111(11):1505. PMID: 27698387.
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    48. May FP, Reid MW, Cohen S, Dailey F, Spiegel BM. Predictive overbooking and active recruitment increases uptake of endoscopy appointments among African American patients. Gastrointest Endosc. 2017 Apr; 85(4):700-705. PMID: 27623103.
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    49. May FP, Whitman CB, Varlyguina K, Bromley EG, Spiegel BM. Addressing Low Colorectal Cancer Screening in African Americans: Using Focus Groups to Inform the Development of Effective Interventions. J Cancer Educ. 2016 09; 31(3):567-74. PMID: 25963898.
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    50. Daskivich TJ, Spiegel B, Kim HL. Online Ratings Systems for Physicians and Institutions: Limitations of the Current State of the Art. Eur Urol. 2017 03; 71(3):311-312. PMID: 27567211.
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    51. Almario CV, Chey WD, Khanna D, Mosadeghi S, Ahmed S, Afghani E, Whitman C, Fuller G, Reid M, Bolus R, Dennis B, Encarnacion R, Martinez B, Soares J, Modi R, Agarwal N, Lee A, Kubomoto S, Sharma G, Bolus S, Spiegel BM. Impact of National Institutes of Health Gastrointestinal PROMIS Measures in Clinical Practice: Results of a Multicenter Controlled Trial. Am J Gastroenterol. 2016 Nov; 111(11):1546-1556. PMID: 27481311.
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    52. Reid MW, May FP, Martinez B, Cohen S, Wang H, Williams DL, Spiegel BM. Preventing Endoscopy Clinic No-Shows: Prospective Validation of a Predictive Overbooking Model. Am J Gastroenterol. 2016 09; 111(9):1267-73. PMID: 27377518.
      View in: PubMed
    53. Almario CV, May FP, Maxwell AE, Ren W, Ponce NA, Spiegel BM. Persistent racial and ethnic disparities in flu vaccination coverage: Results from a population-based study. Am J Infect Control. 2016 09 01; 44(9):1004-9. PMID: 27372226.
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    54. Chiang AL, Vartabedian B, Spiegel B. Harnessing the Hashtag: A Standard Approach to GI Dialogue on Social Media. Am J Gastroenterol. 2016 Aug; 111(8):1082-4. PMID: 27349338.
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    55. Mosadeghi S, Reid MW, Martinez B, Rosen BT, Spiegel BM. Feasibility of an Immersive Virtual Reality Intervention for Hospitalized Patients: An Observational Cohort Study. JMIR Ment Health. 2016 Jun 27; 3(2):e28. PMID: 27349654.
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    56. Dominitz JA, Spiegel B. Editorial: On the Quality of Quality Metrics: Rethinking What Defines a Good Colonoscopy. Am J Gastroenterol. 2016 05; 111(5):730-2. PMID: 27151122.
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    57. Irvine EJ, Tack J, Crowell MD, Gwee KA, Ke M, Schmulson MJ, Whitehead WE, Spiegel B. Design of Treatment Trials for Functional Gastrointestinal Disorders. Gastroenterology. 2016 May; 150(6):1469-1480.e1. PMID: 27147123.
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    58. Spiegel B. 2015 American Journal of Gastroenterology Lecture: How Digital Health Will Transform Gastroenterology. Am J Gastroenterol. 2016 05; 111(5):624-30. PMID: 27045930.
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    59. Palsson OS, Whitehead WE, van Tilburg MA, Chang L, Chey W, Crowell MD, Keefer L, Lembo AJ, Parkman HP, Rao SS, Sperber A, Spiegel B, Tack J, Vanner S, Walker LS, Whorwell P, Yang Y. Rome IV Diagnostic Questionnaires and Tables for Investigators and Clinicians. Gastroenterology. 2016 Feb 13. PMID: 27144634.
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    60. Lacy BE, Spiegel B. The American Journal of Gastroenterology in 2016: Where Have We Been? Where Are We Going? Am J Gastroenterol. 2016 Jan; 111(1):1-3. PMID: 26753890.
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    61. Reid MW, Cohen S, Wang H, Kaung A, Patel A, Tashjian V, Williams DL, Martinez B, Spiegel BM. Preventing patient absenteeism: validation of a predictive overbooking model. Am J Manag Care. 2015 Dec; 21(12):902-10. PMID: 26671702.
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    62. Almario CV, May FP, Shaheen NJ, Murthy R, Gupta K, Jamil LH, Lo SK, Spiegel BM. Cost Utility of Competing Strategies to Prevent Endoscopic Transmission of Carbapenem-Resistant Enterobacteriaceae. Am J Gastroenterol. 2015 Dec; 110(12):1666-74. PMID: 26526083.
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    63. Kaneshiro M, Kaiser W, Pourmorady J, Fleshner P, Russell M, Zaghiyan K, Lin A, Martinez B, Patel A, Nguyen A, Singh D, Zegarski V, Reid M, Dailey F, Xu J, Robbins K, Spiegel B. Postoperative Gastrointestinal Telemetry with an Acoustic Biosensor Predicts Ileus vs. Uneventful GI Recovery. J Gastrointest Surg. 2016 Jan; 20(1):132-9; discussion 139. PMID: 26408329.
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    64. Whitman CB, Reid MW, Arnold C, Patel H, Ursos L, Sa'adon R, Pourmorady J, Spiegel BM. Balancing opioid-induced gastrointestinal side effects with pain management: Insights from the online community. J Opioid Manag. 2015 Sep-Oct; 11(5):383-91. PMID: 26535966.
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    65. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The Effect of Dietary Intervention on Irritable Bowel Syndrome: A Systematic Review. Clin Transl Gastroenterol. 2015 Aug 20; 6:e107. PMID: 26291435; PMCID: PMC4816279.
    66. Almario CV, Chey WD, Iriana S, Dailey F, Robbins K, Patel AV, Reid M, Whitman C, Fuller G, Bolus R, Dennis B, Encarnacion R, Martinez B, Soares J, Modi R, Agarwal N, Lee A, Kubomoto S, Sharma G, Bolus S, Chang L, Spiegel BM. Computer versus physician identification of gastrointestinal alarm features. Int J Med Inform. 2015 Dec; 84(12):1111-7. PMID: 26254875.
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    67. May FP, Almario CV, Ponce N, Spiegel BM. Racial minorities are more likely than whites to report lack of provider recommendation for colon cancer screening. Am J Gastroenterol. 2015 Oct; 110(10):1388-94. PMID: 25964227.
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    68. Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Corrigendum: development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. Am J Gastroenterol. 2015 Apr; 110(4):608. PMID: 25853211.
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    69. Almario CV, May FP, Ponce NA, Spiegel BM. Racial and Ethnic Disparities in Colonoscopic Examination of Individuals With a Family History of Colorectal Cancer. Clin Gastroenterol Hepatol. 2015 Aug; 13(8):1487-95. PMID: 25737445.
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    70. Jensen RE, Rothrock NE, DeWitt EM, Spiegel B, Tucker CA, Crane HM, Forrest CB, Patrick DL, Fredericksen R, Shulman LM, Cella D, Crane PK. The role of technical advances in the adoption and integration of patient-reported outcomes in clinical care. Med Care. 2015 Feb; 53(2):153-9. PMID: 25588135.
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    71. Bromley EG, May FP, Federer L, Spiegel BM, van Oijen MG. Explaining persistent under-use of colonoscopic cancer screening in African Americans: a systematic review. Prev Med. 2015 Feb; 71:40-8. PMID: 25481094.
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    72. Almario CV, Chey W, Kaung A, Whitman C, Fuller G, Reid M, Nguyen K, Bolus R, Dennis B, Encarnacion R, Martinez B, Talley J, Modi R, Agarwal N, Lee A, Kubomoto S, Sharma G, Bolus S, Chang L, Spiegel BM. Computer-generated vs. physician-documented history of present illness (HPI): results of a blinded comparison. Am J Gastroenterol. 2015 Jan; 110(1):170-9. PMID: 25461620.
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    73. Nagaraja V, Hays RD, Khanna PP, Spiegel BM, Chang L, Melmed GY, Bolus R, Khanna D. Construct validity of the Patient-Reported Outcomes Measurement Information System gastrointestinal symptom scales in systemic sclerosis. Arthritis Care Res (Hoboken). 2014 Nov; 66(11):1725-30. PMID: 24692332; PMCID: PMC4182150.
    74. Spiegel BM, Hays RD, Bolus R, Melmed GY, Chang L, Whitman C, Khanna PP, Paz SH, Hays T, Reise S, Khanna D. Development of the NIH Patient-Reported Outcomes Measurement Information System (PROMIS) gastrointestinal symptom scales. Am J Gastroenterol. 2014 Nov; 109(11):1804-14. PMID: 25199473; PMCID: PMC4285435.
    75. Spiegel BM, Kaneshiro M, Russell MM, Lin A, Patel A, Tashjian VC, Zegarski V, Singh D, Cohen SE, Reid MW, Whitman CB, Talley J, Martinez BM, Kaiser W. Validation of an acoustic gastrointestinal surveillance biosensor for postoperative ileus. J Gastrointest Surg. 2014 Oct; 18(10):1795-803. PMID: 25091837.
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    76. Ford AC, Moayyedi P, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Quigley EM. American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation. Am J Gastroenterol. 2014 Aug; 109 Suppl 1:S2-26; quiz S27. PMID: 25091148.
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    77. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol. 2014 Oct; 109(10):1547-61; quiz 1546, 1562. PMID: 25070051.
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    78. Moayyedi P, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Ford AC. The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109(9):1367-74. PMID: 25070054.
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    79. Spiegel BM, Reid MW, Bolus R, Whitman CB, Talley J, Dea S, Shahedi K, Karsan H, Teal C, Melmed GY, Cohen E, Fuller G, Yen L, Hodgkins P, Erder MH. Development and validation of a disease-targeted quality of life instrument for chronic diverticular disease: the DV-QOL. Qual Life Res. 2015 Jan; 24(1):163-79. PMID: 25059533.
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    80. Ford AC, Quigley EM, Lacy BE, Lembo AJ, Saito YA, Schiller LR, Soffer EE, Spiegel BM, Moayyedi P. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2014 Sep; 109(9):1350-65; quiz 1366. PMID: 24935275.
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    81. Cohen E, Spiegel B. Reply: To PMID 23524129. Clin Gastroenterol Hepatol. 2014 Jul; 12(7):1200. PMID: 24842668.
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    82. Cohen E, Bolus R, Khanna D, Hays RD, Chang L, Melmed GY, Khanna P, Spiegel B. GERD symptoms in the general population: prevalence and severity versus care-seeking patients. Dig Dis Sci. 2014 Oct; 59(10):2488-96. PMID: 24811245; PMCID: PMC4275099.
    83. May FP, Bromley EG, Reid MW, Baek M, Yoon J, Cohen E, Lee A, van Oijen MG, Spiegel BM. Low uptake of colorectal cancer screening among African Americans in an integrated Veterans Affairs health care network. Gastrointest Endosc. 2014 Aug; 80(2):291-8. PMID: 24674351.
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    84. Lackner JM, Gudleski GD, Thakur ER, Stewart TJ, Iacobucci GJ, Spiegel BM. The impact of physical complaints, social environment, and psychological functioning on IBS patients' health perceptions: looking beyond GI symptom severity. Am J Gastroenterol. 2014 Feb; 109(2):224-33. PMID: 24419481.
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    85. Khanna P, Agarwal N, Khanna D, Hays RD, Chang L, Bolus R, Melmed G, Whitman CB, Kaplan RM, Ogawa R, Snyder B, Spiegel BM. Development of an online library of patient-reported outcome measures in gastroenterology: the GI-PRO database. Am J Gastroenterol. 2014 Feb; 109(2):234-48. PMID: 24343547; PMCID: PMC4275098.
    86. Cohen E, Spiegel B. Reply: To PMID 23524129. Clin Gastroenterol Hepatol. 2013 Nov; 11(11):1521-2. PMID: 23954651.
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    87. Whitman CB, Shreay S, Gitlin M, van Oijen MG, Spiegel BM. Clinical factors and the decision to transfuse chronic dialysis patients. Clin J Am Soc Nephrol. 2013 Nov; 8(11):1942-51. PMID: 23929931; PMCID: PMC3817895.
    88. Shahedi K, Fuller G, Bolus R, Cohen E, Vu M, Shah R, Agarwal N, Kaneshiro M, Atia M, Sheen V, Kurzbard N, van Oijen MG, Yen L, Hodgkins P, Erder MH, Spiegel B. Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clin Gastroenterol Hepatol. 2013 Dec; 11(12):1609-13. PMID: 23856358.
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    89. Spiegel B. Diagnostic testing in extraesophageal GERD: another case of "furor medicus"? Am J Gastroenterol. 2013 Jun; 108(6):912-4. PMID: 23735914.
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    90. Spiegel BM. Patient-reported outcomes in gastroenterology: clinical and research applications. J Neurogastroenterol Motil. 2013 Apr; 19(2):137-48. PMID: 23667745; PMCID: PMC3644650.
    91. Cohen E, Fuller G, Bolus R, Modi R, Vu M, Shahedi K, Shah R, Atia M, Kurzbard N, Sheen V, Agarwal N, Kaneshiro M, Yen L, Hodgkins P, Erder MH, Spiegel B. Increased risk for irritable bowel syndrome after acute diverticulitis. Clin Gastroenterol Hepatol. 2013 Dec; 11(12):1614-9. PMID: 23524129.
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    92. Melmed GY, Siegel CA, Spiegel BM, Allen JI, Cima R, Colombel JF, Dassopoulos T, Denson LA, Dudley-Brown S, Garb A, Hanauer SB, Kappelman MD, Lewis JD, Lynch I, Moynihan A, Rubin DT, Sartor RB, Schwartz RM, Wolf DC, Ullman TA. Quality indicators for inflammatory bowel disease: development of process and outcome measures. Inflamm Bowel Dis. 2013 Mar; 19(3):662-8. PMID: 23388547.
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    93. Wang HS, Pisegna J, Modi R, Liang LJ, Atia M, Nguyen M, Cohen H, Ohning G, van Oijen M, Spiegel BM. Adenoma detection rate is necessary but insufficient for distinguishing high versus low endoscopist performance. Gastrointest Endosc. 2013 Jan; 77(1):71-8. PMID: 23261096.
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    94. Surti B, Spiegel B, Ippoliti A, Vasiliauskas EA, Simpson P, Shih DQ, Targan SR, McGovern DP, Melmed GY. Assessing health status in inflammatory bowel disease using a novel single-item numeric rating scale. Dig Dis Sci. 2013 May; 58(5):1313-21. PMID: 23250673; PMCID: PMC4161217.
    95. Spiegel BM. Burden of illness in irritable bowel syndrome: looking beyond the patient. Clin Gastroenterol Hepatol. 2013 Feb; 11(2):156-7. PMID: 23103826.
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    96. Strate LL, Modi R, Cohen E, Spiegel BM. Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights. Am J Gastroenterol. 2012 Oct; 107(10):1486-93. PMID: 22777341.
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    97. Spiegel BM. Treatment center characteristics associated with better outcomes: a role for the medical director? Semin Dial. 2012 May; 25(3):296-8. PMID: 22607212.
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    98. Khanna D, Krishnan E, Dewitt EM, Khanna PP, Spiegel B, Hays RD. The future of measuring patient-reported outcomes in rheumatology: Patient-Reported Outcomes Measurement Information System (PROMIS). Arthritis Care Res (Hoboken). 2011 Nov; 63 Suppl 11:S486-90. PMID: 22588770; PMCID: PMC3302685.
    99. Khanna D, Maranian P, Rothrock N, Cella D, Gershon R, Khanna PP, Spiegel B, Furst DE, Clements PJ, Bechtel A, Hays RD. Feasibility and construct validity of PROMIS and "legacy" instruments in an academic scleroderma clinic. Value Health. 2012 Jan; 15(1):128-34. PMID: 22264980; PMCID: PMC3457915.
    100. Foster T, Hon H, Kanwal F, Han S, Spiegel B. Screening high risk individuals for hepatitis B: physician knowledge, attitudes, and beliefs. Dig Dis Sci. 2011 Dec; 56(12):3471-87. PMID: 22001940.
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    101. Huang ES, Karsan S, Kanwal F, Singh I, Makhani M, Spiegel BM. Impact of nasogastric lavage on outcomes in acute GI bleeding. Gastrointest Endosc. 2011 Nov; 74(5):971-80. PMID: 21737077.
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    102. Au K, Singh MK, Bodukam V, Bae S, Maranian P, Ogawa R, Spiegel B, McMahon M, Hahn B, Khanna D. Atherosclerosis in systemic sclerosis: a systematic review and meta-analysis. Arthritis Rheum. 2011 Jul; 63(7):2078-90. PMID: 21480189.
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    103. Spiegel B. Two weeks of rifaximin relieves global symptoms and bloating in people with IBS without constipation. Evid Based Med. 2011 Oct; 16(5):156-7. PMID: 21515920.
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    104. Spiegel BM, Talley J, Shekelle P, Agarwal N, Snyder B, Bolus R, Kurzbard N, Chan M, Ho A, Kaneshiro M, Cordasco K, Cohen H. Development and validation of a novel patient educational booklet to enhance colonoscopy preparation. Am J Gastroenterol. 2011 May; 106(5):875-83. PMID: 21483463.
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    105. Spiegel BM. Questioning the bacterial overgrowth hypothesis of irritable bowel syndrome: an epidemiologic and evolutionary perspective. Clin Gastroenterol Hepatol. 2011 Jun; 9(6):461-9; quiz e59. PMID: 21397724.
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    106. Spiegel BM. Does time of day affect polyp detection rates from colonoscopy? Gastrointest Endosc. 2011 Mar; 73(3):476-9. PMID: 21353844.
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    107. Agarwal N, Spiegel BM. The effect of irritable bowel syndrome on health-related quality of life and health care expenditures. Gastroenterol Clin North Am. 2011 Mar; 40(1):11-9. PMID: 21333898.
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    108. Spiegel BM, Khanna D, Bolus R, Agarwal N, Khanna P, Chang L. Understanding gastrointestinal distress: a framework for clinical practice. Am J Gastroenterol. 2011 Mar; 106(3):380-5. PMID: 21378758.
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    109. Spiegel BM. How and when to prepare for the GI board examination. Gastrointest Endosc. 2010 Dec; 72(6):1250-2. PMID: 21111875.
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    110. Kaneshiro M, Ho A, Chan M, Cohen H, Spiegel BM. Colonoscopy yields fewer polyps as the day progresses despite using social influence theory to reverse the trend. Gastrointest Endosc. 2010 Dec; 72(6):1233-40. PMID: 21111873.
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    111. Spiegel BM. Treatment strategies for acid reflux: EncomPASSing practical solutions for primary care. Am J Gastroenterol. 2010 Nov; 105(11):2347-9. PMID: 21048680.
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    112. Spiegel B, Bolus R, Desai AA, Zagar P, Parker T, Moran J, Solomon MD, Khawar O, Gitlin M, Talley J, Nissenson A. Dialysis practices that distinguish facilities with below- versus above-expected mortality. Clin J Am Soc Nephrol. 2010 Nov; 5(11):2024-33. PMID: 20876677.
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    113. Chang L, Lacy BE, Spiegel BM. An Evidence-based Approach to Therapy in IBS-D: A Case Study Compendium. Gastroenterol Hepatol (N Y). 2010 Sep; 6(9 Suppl 15):1-12. PMID: 22570639.
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    114. Kanwal F, Barkun A, Gralnek IM, Asch SM, Kuipers EJ, Bardou M, Sung J, Enns R, Agreus L, Armstrong D, Spiegel BM. Measuring quality of care in patients with nonvariceal upper gastrointestinal hemorrhage: development of an explicit quality indicator set. Am J Gastroenterol. 2010 Aug; 105(8):1710-8. PMID: 20686458.
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    115. Spiegel BM, Bolus R, Desai AA, Zager P, Parker T, Moran J, Bolus S, Solomon MD, Khawar O, Gitlin M, Sul H, Talley J, Nissenson A. Dialysis practices that distinguish top- versus bottom-performing facilities by hemoglobin outcomes. Am J Kidney Dis. 2010 Jul; 56(1):86-94. PMID: 20493604.
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    116. Melmed GY, Spiegel BM, Bressler B, Cheifetz AS, Devlin SM, Harrell LE, Irving PM, Jones J, Kaplan GG, Kozuch PL, Velayos FS, Baidoo L, Sparrow MP, Siegel CA. The appropriateness of concomitant immunomodulators with anti-tumor necrosis factor agents for Crohn's disease: one size does not fit all. Clin Gastroenterol Hepatol. 2010 Aug; 8(8):655-9. PMID: 20451665.
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    117. Kanwal F, Kramer J, Asch SM, El-Serag H, Spiegel BM, Edmundowicz S, Sanyal AJ, Dominitz JA, McQuaid KR, Martin P, Keeffe EB, Friedman LS, Ho SB, Durazo F, Bacon BR. An explicit quality indicator set for measurement of quality of care in patients with cirrhosis. Clin Gastroenterol Hepatol. 2010 Aug; 8(8):709-17. PMID: 20385251.
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    118. Chey WD, Spiegel B. Proton pump inhibitors, irritable bowel syndrome, and small intestinal bacterial overgrowth: coincidence or Newton's third law revisited? Clin Gastroenterol Hepatol. 2010 Jun; 8(6):480-2. PMID: 20304096.
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    119. Spiegel BM, Farid M, Esrailian E, Talley J, Chang L. Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts. Am J Gastroenterol. 2010 Apr; 105(4):848-58. PMID: 20197761.
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    120. Laine L, Spiegel B, Rostom A, Moayyedi P, Kuipers EJ, Bardou M, Sung J, Barkun AN. Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommendations from an international consensus conference. Am J Gastroenterol. 2010 Mar; 105(3):540-50. PMID: 20029415.
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    121. Weinberg BM, Spiegel BM, Tomlinson JS, Farrell JJ. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology. 2010 Feb; 138(2):531-40. PMID: 19818780; PMCID: PMC2949077.
    122. Spiegel B, Camilleri M, Bolus R, Andresen V, Chey WD, Fehnel S, Mangel A, Talley NJ, Whitehead WE. Psychometric evaluation of patient-reported outcomes in irritable bowel syndrome randomized controlled trials: a Rome Foundation report. Gastroenterology. 2009 Dec; 137(6):1944-53.e1-3. PMID: 19706292.
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    123. Ford AC, Spiegel BM, Talley NJ, Moayyedi P. Small intestinal bacterial overgrowth in irritable bowel syndrome: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2009 Dec; 7(12):1279-86. PMID: 19602448.
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    124. Spiegel BM. The burden of IBS: looking at metrics. Curr Gastroenterol Rep. 2009 Aug; 11(4):265-9. PMID: 19615301.
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    125. Spiegel BM. Endoscopy for acute upper GI tract hemorrhage: sooner is better. Gastrointest Endosc. 2009 Aug; 70(2):236-9. PMID: 19631802.
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    126. Chan MY, Cohen H, Spiegel BM. Fewer polyps detected by colonoscopy as the day progresses at a Veteran's Administration teaching hospital. Clin Gastroenterol Hepatol. 2009 Nov; 7(11):1217-23; quiz 1143. PMID: 19631284.
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    127. Desai AA, Nissenson A, Chertow GM, Farid M, Singh I, Van Oijen MG, Esrailian E, Solomon MD, Spiegel BM. The relationship between laboratory-based outcome measures and mortality in end-stage renal disease: a systematic review. Hemodial Int. 2009 Jul; 13(3):347-59. PMID: 19583604.
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    128. Spiegel B, Harris L, Lucak S, Mayer E, Naliboff B, Bolus R, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Dulai G, Talley J, Chang L. Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF Cohort. Am J Gastroenterol. 2009 Aug; 104(8):1984-91. PMID: 19491835; PMCID: PMC3839573.
    129. Ford AC, Chey WD, Talley NJ, Malhotra A, Spiegel BM, Moayyedi P. Yield of diagnostic tests for celiac disease in individuals with symptoms suggestive of irritable bowel syndrome: systematic review and meta-analysis. Arch Intern Med. 2009 Apr 13; 169(7):651-8. PMID: 19364994.
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    130. Desai AA, Bolus R, Nissenson A, Chertow GM, Bolus S, Solomon MD, Khawar OS, Talley J, Spiegel BM. Is there "cherry picking" in the ESRD Program? Perceptions from a Dialysis Provider Survey. Clin J Am Soc Nephrol. 2009 Apr; 4(4):772-7. PMID: 19339407; PMCID: PMC2666440.
    131. Kanwal F, Gralnek IM, Hays RD, Zeringue A, Durazo F, Han SB, Saab S, Bolus R, Spiegel BM. Health-related quality of life predicts mortality in patients with advanced chronic liver disease. Clin Gastroenterol Hepatol. 2009 Jul; 7(7):793-9. PMID: 19306949.
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    132. Brandt LJ, Chey WD, Foxx-Orenstein AE, Schiller LR, Schoenfeld PS, Spiegel BM, Talley NJ, Quigley EM. An evidence-based position statement on the management of irritable bowel syndrome. Am J Gastroenterol. 2009 Jan; 104 Suppl 1:S1-35. PMID: 19521341.
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    133. Spiegel BM, Chey WD, Chang L. Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors? Am J Gastroenterol. 2008 Dec; 103(12):2972-6. PMID: 19086951.
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    134. Greengold B, Nyamathi A, Kominski G, Wiley D, Lewis MA, Hodge F, Singer M, Spiegel B. Cost-effectiveness analysis of behavioral interventions to improve vaccination compliance in homeless adults. Vaccine. 2009 Jan 29; 27(5):718-25. PMID: 19041351; PMCID: PMC2772200.
    135. Ford AC, Talley NJ, Spiegel BM, Foxx-Orenstein AE, Schiller L, Quigley EM, Moayyedi P. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ. 2008 Nov 13; 337:a2313. PMID: 19008265; PMCID: PMC2583392.
    136. Spiegel BM, Melmed G, Robbins S, Esrailian E. Biomarkers and health-related quality of life in end-stage renal disease: a systematic review. Clin J Am Soc Nephrol. 2008 Nov; 3(6):1759-68. PMID: 18832106; PMCID: PMC2572281.
    137. Spiegel BM, Ho W, Esrailian E, Targan S, Higgins PD, Siegel CA, Dubinsky M, Melmed GY. Controversies in ulcerative colitis: a survey comparing decision making of experts versus community gastroenterologists. Clin Gastroenterol Hepatol. 2009 Feb; 7(2):168-74, 174.e1. PMID: 18952199; PMCID: PMC3804428.
    138. Ho W, Spiegel BM. The relationship between obesity and functional gastrointestinal disorders: causation, association, or neither? Gastroenterol Hepatol (N Y). 2008 Aug; 4(8):572-8. PMID: 21960939; PMCID: PMC3096111.
    139. Spiegel B, Strickland A, Naliboff BD, Mayer EA, Chang L. Predictors of patient-assessed illness severity in irritable bowel syndrome. Am J Gastroenterol. 2008 Oct; 103(10):2536-43. PMID: 18637089.
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    140. Desai AA, Bolus R, Nissenson A, Bolus S, Solomon MD, Khawar O, Gitlin M, Talley J, Spiegel BM. Identifying best practices in dialysis care: results of cognitive interviews and a national survey of dialysis providers. Clin J Am Soc Nephrol. 2008 Jul; 3(4):1066-76. PMID: 18417745; PMCID: PMC2440275.
    141. Slavenburg S, van Oijen MG, Spiegel BM. Comparison of health-related quality of life between populations. Liver Int. 2008 Feb; 28(2):285-6; author reply 286-7. PMID: 18251985.
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    142. Kanwal F, Hoang T, Spiegel BM, Eisen S, Dominitz JA, Gifford A, Goetz M, Asch SM. Predictors of treatment in patients with chronic hepatitis C infection - role of patient versus nonpatient factors. Hepatology. 2007 Dec; 46(6):1741-9. PMID: 18046707.
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    143. Spiegel BM, Esrailian E, Eisen G. The budget impact of endoscopic screening for esophageal varices in cirrhosis. Gastrointest Endosc. 2007 Oct; 66(4):679-92. PMID: 17905009.
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    144. Spiegel BM, Bolus R, Han S, Tong M, Esrailian E, Talley J, Tran T, Smith J, Karsan HA, Durazo F, Bacon B, Martin P, Younossi Z, Hwa-Ong S, Kanwal F. Development and validation of a disease-targeted quality of life instrument in chronic hepatitis B: the hepatitis B quality of life instrument, version 1.0. Hepatology. 2007 Jul; 46(1):113-21. PMID: 17596882.
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    145. Spiegel BM. Do physicians follow evidence-based guidelines in the diagnostic work-up of IBS? Nat Clin Pract Gastroenterol Hepatol. 2007 Jun; 4(6):296-7. PMID: 17541444.
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    146. Spiegel BM, Esrailian E, Laine L, Chamberlain MC. Clinical impact of adjuvant chemotherapy in glioblastoma multiforme : a meta-analysis. CNS Drugs. 2007; 21(9):775-87. PMID: 17696576.
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    147. Gralnek IM, Dulai GS, Fennerty MB, Spiegel BM. Esomeprazole versus other proton pump inhibitors in erosive esophagitis: a meta-analysis of randomized clinical trials. Clin Gastroenterol Hepatol. 2006 Dec; 4(12):1452-8. PMID: 17162239.
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    148. Singh H, Latosinsky S, Spiegel BM, Targownik LE. The cost-effectiveness of colonic stenting as a bridge to curative surgery in patients with acute left-sided malignant colonic obstruction: a Canadian perspective. Can J Gastroenterol. 2006 Dec; 20(12):779-85. PMID: 17171197; PMCID: PMC2660835.
    149. Kanwal F, Farid M, Martin P, Chen G, Gralnek IM, Dulai GS, Spiegel BM. Treatment alternatives for hepatitis B cirrhosis: a cost-effectiveness analysis. Am J Gastroenterol. 2006 Sep; 101(9):2076-89. PMID: 16968510.
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    150. Spiegel BM, Dulai GS, Lim BS, Mann N, Kanwal F, Gralnek IM. The cost-effectiveness and budget impact of intravenous versus oral proton pump inhibitors in peptic ulcer hemorrhage. Clin Gastroenterol Hepatol. 2006 Aug; 4(8):988-997. PMID: 16844422.
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    151. Spiegel BM, Farid M, Dulai GS, Gralnek IM, Kanwal F. Comparing rates of dyspepsia with Coxibs vs NSAID+PPI: a meta-analysis. Am J Med. 2006 May; 119(5):448.e27-36. PMID: 16651060.
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    152. Spiegel BM, Gralnek IM, Bolus R, Chang L, Dulai GS, Naliboff B, Mayer EA. Is a negative colonoscopy associated with reassurance or improved health-related quality of life in irritable bowel syndrome? Gastrointest Endosc. 2005 Dec; 62(6):892-9. PMID: 16301033.
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    153. Spiegel BM, Kanwal F, Naliboff B, Mayer E. The impact of somatization on the use of gastrointestinal health-care resources in patients with irritable bowel syndrome. Am J Gastroenterol. 2005 Oct; 100(10):2262-73. PMID: 16181379.
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    154. Spiegel BM, Chen K, Chiou CF, Robbins S, Younossi ZM. Erythropoietic growth factors for treatment-induced anemia in hepatitis C: a cost-effectiveness analysis. Clin Gastroenterol Hepatol. 2005 Oct; 3(10):1034-42. PMID: 16234051.
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    155. Kanwal F, Gralnek IM, Hays RD, Dulai GS, Spiegel BM, Bozzette S, Asch S. Impact of chronic viral hepatitis on health-related quality of life in HIV: results from a nationally representative sample. Am J Gastroenterol. 2005 Sep; 100(9):1984-94. PMID: 16128943.
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    156. Kanwal F, Gralnek IM, Martin P, Dulai GS, Farid M, Spiegel BM. Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis. Ann Intern Med. 2005 May 17; 142(10):821-31. PMID: 15897532.
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    157. Spiegel BM, Chiou CF, Ofman JJ. Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups. Arthritis Rheum. 2005 Apr 15; 53(2):185-97. PMID: 15818647.
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    158. Bloom MA, Barghout V, Kahler KH, Bentkover J, Kurth H, Gralnek IM, Spiegel BM. Budget impact of tegaserod on a managed care organization formulary. Am J Manag Care. 2005 Apr; 11(1 Suppl):S27-34. PMID: 15926761.
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    159. Spiegel BM, Younossi ZM, Hays RD, Revicki D, Robbins S, Kanwal F. Impact of hepatitis C on health related quality of life: a systematic review and quantitative assessment. Hepatology. 2005 Apr; 41(4):790-800. PMID: 15791608.
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    160. Dulai GS, Shekelle PG, Jensen DM, Spiegel BM, Chen J, Oh D, Kahn KL. Dysplasia and risk of further neoplastic progression in a regional Veterans Administration Barrett's cohort. Am J Gastroenterol. 2005 Apr; 100(4):775-83. PMID: 15784018.
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    161. Karsan HA, Morton SC, Shekelle PG, Spiegel BM, Suttorp MJ, Edelstein MA, Gralnek IM. Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysis. Dig Dis Sci. 2005 Feb; 50(2):399-406. PMID: 15745108.
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    162. Targownik LE, Spiegel BM, Sack J, Hines OJ, Dulai GS, Gralnek IM, Farrell JJ. Colonic stent vs. emergency surgery for management of acute left-sided malignant colonic obstruction: a decision analysis. Gastrointest Endosc. 2004 Dec; 60(6):865-74. PMID: 15604999.
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    163. Spiegel BM, Gralnek IM, Bolus R, Chang L, Dulai GS, Mayer EA, Naliboff B. Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch Intern Med. 2004 Sep 13; 164(16):1773-80. PMID: 15364671.
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    164. Spiegel BM, Targownik LE, Kanwal F, Derosa V, Dulai GS, Gralnek IM, Chiou CF. The quality of published health economic analyses in digestive diseases: a systematic review and quantitative appraisal. Gastroenterology. 2004 Aug; 127(2):403-11. PMID: 15300571.
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    165. Targownik LE, Spiegel BM, Dulai GS, Karsan HA, Gralnek IM. The cost-effectiveness of hepatic venous pressure gradient monitoring in the prevention of recurrent variceal hemorrhage. Am J Gastroenterol. 2004 Jul; 99(7):1306-15. PMID: 15233670.
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    166. Spiegel BM, DeRosa VP, Gralnek IM, Wang V, Dulai GS. Testing for celiac sprue in irritable bowel syndrome with predominant diarrhea: a cost-effectiveness analysis. Gastroenterology. 2004 Jun; 126(7):1721-32. PMID: 15188167.
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    167. Targownik LE, Gralnek IM, Dulai GS, Spiegel BM, Oei T, Bernstein CN. Management of acute nonvariceal upper gastrointestinal hemorrhage: comparison of an American and a Canadian medical centre. Can J Gastroenterol. 2003 Aug; 17(8):489-95. PMID: 12945010.
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    168. Spiegel BM, Targownik L, Dulai GS, Gralnek IM. The cost-effectiveness of cyclooxygenase-2 selective inhibitors in the management of chronic arthritis. Ann Intern Med. 2003 May 20; 138(10):795-806. PMID: 12755551.
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    169. Spiegel BM, Targownik L, Dulai GS, Karsan HA, Gralnek IM. Endoscopic screening for esophageal varices in cirrhosis: Is it ever cost effective? Hepatology. 2003 Feb; 37(2):366-77. PMID: 12540787.
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    170. Spiegel BM, Ofman JJ, Woods K, Vakil NB. Minimizing recurrent peptic ulcer hemorrhage after endoscopic hemostasis: the cost-effectiveness of competing strategies. Am J Gastroenterol. 2003 Jan; 98(1):86-97. PMID: 12526942.
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    171. Spiegel BM, Vakil NB, Ofman JJ. Dyspepsia management in primary care: a decision analysis of competing strategies. Gastroenterology. 2002 May; 122(5):1270-85. PMID: 11984514.
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