Koehler Carla

TitleLab Director
InstitutionUniversity of California Los Angeles
DepartmentKoehler Lab
AddressMail Code: 156905
607 Charles Young Drive East
Los Angeles CA 90095
Phone1 (310) 825-8427
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    Other Positions


    Collapse Research 
    Collapse Research Activities and Funding
    Small Molecule Probes to Correct AGT Mistargeting in Primary Hyperoxaluria 1
    NIH/NIDDK R01DK101780Aug 21, 2015 - Jun 30, 2018
    Role: Principal Investigator
    Mitochondrial Assembly and Dynamics in Health and Disease
    NIH/NINDS R13NS066552Jul 1, 2009 - Jun 30, 2010
    Role: Principal Investigator
    Small molecule modulators for mitochondrial protein import
    NIH/NIDA R03DA027714Jun 1, 2009 - May 31, 2010
    Role: Principal Investigator
    Small Molecule Modulators for Redox Regulation in the Mitochondrial Intermembrane
    NIH/NIMH R03MH085683Sep 30, 2008 - Aug 31, 2009
    Role: Principal Investigator
    Multi-user fermentation facility upgrade
    NIH/NCRR S10RR023749May 1, 2008 - Apr 30, 2010
    Role: Principal Investigator
    2007 Protein Transport Across Membranes Gordon Conference
    NIH/NIGMS R13GM080876Apr 1, 2007 - Mar 31, 2008
    Role: Principal Investigator
    Cardiolipin remodeling and its role in mitochondrial function in Barth Syndrome
    NIH/NHLBI R21HL082801May 1, 2006 - Oct 31, 2009
    Role: Principal Investigator
    RNA trafficking in mitochondria
    NIH/NIGMS R01GM073981Jan 1, 2006 - Jun 30, 2018
    Role: Principal Investigator
    Fluorescent microscope and imaging system
    NIH/NCRR S10RR019009Apr 15, 2004 - Apr 14, 2005
    Role: Principal Investigator
    Mitochondrial biogenesis &neurodegenerative disorders
    NIH/NIDCD R21DC006663Apr 1, 2004 - Mar 31, 2006
    Role: Principal Investigator
    NIH/NCRR S10RR015955Apr 1, 2001 - Mar 31, 2002
    Role: Principal Investigator
    NIH/NIGMS R01GM061721Sep 1, 2000 - Jul 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Francois-Moutal L, Jahanbakhsh S, Nelson A, Ray D, Scott DD, Hennefarth M, Moutal A, Perez-Miller S, Ambrose AJ, Al-Shamari A, Coursodon P, Meechoovet B, Reiman R, Lyons E, Beilstein M, Chapman E, Morris QD, Van Keuren-Jensen K, Hughes TR, Khanna R, Koehler C, Jen J, Gokhale V, Khanna M. A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). ACS Chem Biol. 2018 Aug 24. PMID: 30141626.
      View in: PubMed
    2. Shimada E, Ahsan FM, Nili M, Huang D, Atamdede S, TeSlaa T, Case D, Yu X, Gregory BD, Perrin BJ, Koehler CM, Teitell MA. PNPase knockout results in mtDNA loss and an altered metabolic gene expression program. PLoS One. 2018; 13(7):e0200925. PMID: 30024931.
      View in: PubMed
    3. Steffen J, Koehler CM. ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. J Cell Biol. 2018 Jan 02; 217(1):15-17. PMID: 29259094.
      View in: PubMed
    4. Filipuzzi I, Steffen J, Germain M, Goepfert L, Conti MA, Potting C, Cerino R, Pfeifer M, Krastel P, Hoepfner D, Bastien J, Koehler CM, Helliwell SB. Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import. Nat Chem Biol. 2017 Dec; 13(12):1239-1244. PMID: 28991239.
      View in: PubMed
    5. Neal SE, Dabir DV, Wijaya J, Boon C, Koehler CM. Osm1 facilitates the transfer of electrons from Erv1 to fumarate in the redox-regulated import pathway in the mitochondrial intermembrane space. Mol Biol Cell. 2017 Oct 15; 28(21):2773-2785. PMID: 28814504.
      View in: PubMed
    6. Sangwan S, Zhao A, Adams KL, Jayson CK, Sawaya MR, Guenther EL, Pan AC, Ngo J, Moore DM, Soriaga AB, Do TD, Goldschmidt L, Nelson R, Bowers MT, Koehler CM, Shaw DE, Novitch BG, Eisenberg DS. Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A. 2017 Aug 15; 114(33):8770-8775. PMID: 28760994.
      View in: PubMed
    7. Miyata N, Tang Z, Conti MA, Johnson ME, Douglas CJ, Hasson SA, Damoiseaux R, Chang CA, Koehler CM. Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. J Biol Chem. 2017 Mar 31; 292(13):5429-5442. PMID: 28167535.
      View in: PubMed
    8. Thangamani S, Maland M, Mohammad H, Pascuzzi PE, Avramova L, Koehler CM, Hazbun TR, Seleem MN. Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway. Front Cell Infect Microbiol. 2017; 7:4. PMID: 28149831.
      View in: PubMed
    9. Steffen J, Vashisht AA, Wan J, Jen JC, Claypool SM, Wohlschlegel JA, Koehler CM. Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. Mol Biol Cell. 2017 Mar 01; 28(5):600-612. PMID: 28057766.
      View in: PubMed
    10. Wan J, Steffen J, Yourshaw M, Mamsa H, Andersen E, Rudnik-Schöneborn S, Pope K, Howell KB, McLean CA, Kornberg AJ, Joseph J, Lockhart PJ, Zerres K, Ryan MM, Nelson SF, Koehler CM, Jen JC. Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia. Brain. 2016 11 01; 139(11):2877-2890. PMID: 27543974.
      View in: PubMed
    11. Wu TH, Sagullo E, Case D, Zheng X, Li Y, Hong JS, TeSlaa T, Patananan AN, McCaffery JM, Niazi K, Braas D, Koehler CM, Graeber TG, Chiou PY, Teitell MA. Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells. Cell Metab. 2016 May 10; 23(5):921-9. PMID: 27166949.
      View in: PubMed
    12. Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2016 Apr 15; 35(8):899. PMID: 27084758; PMCID: PMC4972131.
    13. Lu YW, Galbraith L, Herndon JD, Lu YL, Pras-Raves M, Vervaart M, Van Kampen A, Luyf A, Koehler CM, McCaffery JM, Gottlieb E, Vaz FM, Claypool SM. Defining functional classes of Barth syndrome mutation in humans. Hum Mol Genet. 2016 05 01; 25(9):1754-70. PMID: 26908608; PMCID: PMC4986330 [Available on 05/01/17].
    14. Setoguchi K, TeSlaa T, Koehler CM, Teitell MA. P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells. J Mol Biol. 2016 Apr 10; 428(7):1465-75. PMID: 26239243; PMCID: PMC4733597 [Available on 04/10/17].
    15. Neal SE, Dabir DV, Tienson HL, Horn DM, Glaeser K, Ogozalek Loo RR, Barrientos A, Koehler CM. Mia40 Protein Serves as an Electron Sink in the Mia40-Erv1 Import Pathway. J Biol Chem. 2015 Aug 21; 290(34):20804-14. PMID: 26085103; PMCID: PMC4543643.
    16. Wang G, Shimada E, Nili M, Koehler CM, Teitell MA. Mitochondria-targeted RNA import. Methods Mol Biol. 2015; 1264:107-16. PMID: 25631008; PMCID: PMC4439183.
    17. Steffen J, Koehler CM. The great escape: Mgr2 of the mitochondrial TIM23 translocon is a gatekeeper Tasked with releasing membrane proteins. Mol Cell. 2014 Dec 04; 56(5):613-4. PMID: 25479635.
      View in: PubMed
    18. Xie Y, Zhang J, Lin Y, Gaeta X, Meng X, Wisidagama DR, Cinkornpumin J, Koehler CM, Malone CS, Teitell MA, Lowry WE. Defining the role of oxygen tension in human neural progenitor fate. Stem Cell Reports. 2014 Nov 11; 3(5):743-57. PMID: 25418722; PMCID: PMC4235163.
    19. Miyata N, Steffen J, Johnson ME, Fargue S, Danpure CJ, Koehler CM. Pharmacologic rescue of an enzyme-trafficking defect in primary hyperoxaluria 1. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):14406-11. PMID: 25237136; PMCID: PMC4210028.
    20. Yien YY, Robledo RF, Schultz IJ, Takahashi-Makise N, Gwynn B, Bauer DE, Dass A, Yi G, Li L, Hildick-Smith GJ, Cooney JD, Pierce EL, Mohler K, Dailey TA, Miyata N, Kingsley PD, Garone C, Hattangadi SM, Huang H, Chen W, Keenan EM, Shah DI, Schlaeger TM, DiMauro S, Orkin SH, Cantor AB, Palis J, Koehler CM, Lodish HF, Kaplan J, Ward DM, Dailey HA, Phillips JD, Peters LL, Paw BH. TMEM14C is required for erythroid mitochondrial heme metabolism. J Clin Invest. 2014 Oct; 124(10):4294-304. PMID: 25157825; PMCID: PMC4191016.
    21. Hildick-Smith GJ, Cooney JD, Garone C, Kremer LS, Haack TB, Thon JN, Miyata N, Lieber DS, Calvo SE, Akman HO, Yien YY, Huston NC, Branco DS, Shah DI, Freedman ML, Koehler CM, Italiano JE, Merkenschlager A, Beblo S, Strom TM, Meitinger T, Freisinger P, Donati MA, Prokisch H, Mootha VK, DiMauro S, Paw BH. Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4. Am J Hum Genet. 2013 Nov 07; 93(5):906-14. PMID: 24119684; PMCID: PMC3824126.
    22. Herndon JD, Claypool SM, Koehler CM. The Taz1p transacylase is imported and sorted into the outer mitochondrial membrane via a membrane anchor domain. Eukaryot Cell. 2013 Dec; 12(12):1600-8. PMID: 24078306; PMCID: PMC3889572.
    23. Koehler C. Carla Koehler: Small TIMs are a big deal. Interviewed by Caitlin Sedwick. J Cell Biol. 2013 Apr 29; 201(3):358-9. PMID: 23629962; PMCID: PMC3639390.
    24. Dabir DV, Hasson SA, Setoguchi K, Johnson ME, Wongkongkathep P, Douglas CJ, Zimmerman J, Damoiseaux R, Teitell MA, Koehler CM. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15; 25(1):81-92. PMID: 23597483; PMCID: PMC3726224.
    25. Arango NA, Li L, Dabir D, Nicolau F, Pieretti-Vanmarcke R, Koehler C, McCarrey JR, Lu N, Donahoe PK. Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice. Biol Reprod. 2013 Mar; 88(3):76. PMID: 23269666; PMCID: PMC4013860.
    26. Levesque MP, Krauss J, Koehler C, Boden C, Harris MP. New tools for the identification of developmentally regulated enhancer regions in embryonic and adult zebrafish. Zebrafish. 2013 Mar; 10(1):21-9. PMID: 23461416; PMCID: PMC3670562.
    27. Zhang J, Nuebel E, Daley GQ, Koehler CM, Teitell MA. Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. Cell Stem Cell. 2012 Nov 02; 11(5):589-95. PMID: 23122286; PMCID: PMC3492890.
    28. von Ameln S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C. A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet. 2012 Nov 02; 91(5):919-27. PMID: 23084290; PMCID: PMC3487123.
    29. Bourens M, Dabir DV, Tienson HL, Sorokina I, Koehler CM, Barrientos A. Role of twin Cys-Xaa9-Cys motif cysteines in mitochondrial import of the cytochrome C oxidase biogenesis factor Cmc1. J Biol Chem. 2012 Sep 07; 287(37):31258-69. PMID: 22767599; PMCID: PMC3438957.
    30. Zhang J, Nuebel E, Wisidagama DR, Setoguchi K, Hong JS, Van Horn CM, Imam SS, Vergnes L, Malone CS, Koehler CM, Teitell MA. Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. Nat Protoc. 2012 May 10; 7(6):1068-85. PMID: 22576106; PMCID: PMC3819135.
    31. Wang G, Shimada E, Zhang J, Hong JS, Smith GM, Teitell MA, Koehler CM. Correcting human mitochondrial mutations with targeted RNA import. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4840-5. PMID: 22411789; PMCID: PMC3323963.
    32. Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2011 Nov 15; 30(24):4860-73. PMID: 22085932; PMCID: PMC3243621.
    33. Claypool SM, Koehler CM. The complexity of cardiolipin in health and disease. Trends Biochem Sci. 2012 Jan; 37(1):32-41. PMID: 22014644; PMCID: PMC3259273.
    34. Wang G, Shimada E, Koehler CM, Teitell MA. PNPASE and RNA trafficking into mitochondria. Biochim Biophys Acta. 2012 Sep-Oct; 1819(9-10):998-1007. PMID: 22023881; PMCID: PMC3267854.
    35. Claypool SM, Whited K, Srijumnong S, Han X, Koehler CM. Barth syndrome mutations that cause tafazzin complex lability. J Cell Biol. 2011 Feb 07; 192(3):447-62. PMID: 21300850; PMCID: PMC3101092.
    36. Wang G, Chen HW, Oktay Y, Zhang J, Allen EL, Smith GM, Fan KC, Hong JS, French SW, McCaffery JM, Lightowlers RN, Morse HC, Koehler CM, Teitell MA. PNPASE regulates RNA import into mitochondria. Cell. 2010 Aug 06; 142(3):456-67. PMID: 20691904.
      View in: PubMed
    37. Curado S, Ober EA, Walsh S, Cortes-Hernandez P, Verkade H, Koehler CM, Stainier DY. The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model. Dis Model Mech. 2010 Jul-Aug; 3(7-8):486-95. PMID: 20483998; PMCID: PMC2898538.
    38. Hasson SA, Damoiseaux R, Glavin JD, Dabir DV, Walker SS, Koehler CM. Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9578-83. PMID: 20457929; PMCID: PMC2906835.
    39. Zaltsman Y, Shachnai L, Yivgi-Ohana N, Schwarz M, Maryanovich M, Houtkooper RH, Vaz FM, De Leonardis F, Fiermonte G, Palmieri F, Gillissen B, Daniel PT, Jimenez E, Walsh S, Koehler CM, Roy SS, Walter L, Hajnóczky G, Gross A. MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria. Nat Cell Biol. 2010 Jun; 12(6):553-562. PMID: 20436477; PMCID: PMC4070879.
    40. Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon LA, Schon EA. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol. 2009 Nov; 175(5):1810-6. PMID: 19834068; PMCID: PMC2774047.
    41. Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell. 2009 Aug 21; 138(4):628-44. PMID: 19703392; PMCID: PMC4099469.
    42. Tienson HL, Dabir DV, Neal SE, Loo R, Hasson SA, Boontheung P, Kim SK, Loo JA, Koehler CM. Reconstitution of the mia40-erv1 oxidative folding pathway for the small tim proteins. Mol Biol Cell. 2009 Aug; 20(15):3481-90. PMID: 19477928; PMCID: PMC2719566.
    43. Lu G, Sun H, Korge P, Koehler CM, Weiss JN, Wang Y. Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation. Methods Enzymol. 2009; 457:255-73. PMID: 19426872; PMCID: PMC3705213.
    44. Claypool SM, Boontheung P, McCaffery JM, Loo JA, Koehler CM. The cardiolipin transacylase, tafazzin, associates with two distinct respiratory components providing insight into Barth syndrome. Mol Biol Cell. 2008 Dec; 19(12):5143-55. PMID: 18799610; PMCID: PMC2592642.
    45. Claypool SM, Oktay Y, Boontheung P, Loo JA, Koehler CM. Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane. J Cell Biol. 2008 Sep 08; 182(5):937-50. PMID: 18779372; PMCID: PMC2528576.
    46. Koehler CM, Tienson HL. Redox regulation of protein folding in the mitochondrial intermembrane space. Biochim Biophys Acta. 2009 Jan; 1793(1):139-45. PMID: 18761382; PMCID: PMC4099470.
    47. Walsh S, Koehler CM. Gazing at translocation in the mitochondrion. Cell. 2008 Aug 08; 134(3):382-3. PMID: 18692459.
      View in: PubMed
    48. Beverly KN, Sawaya MR, Schmid E, Koehler CM. The Tim8-Tim13 complex has multiple substrate binding sites and binds cooperatively to Tim23. J Mol Biol. 2008 Oct 24; 382(5):1144-56. PMID: 18706423; PMCID: PMC2651516.
    49. Gebert N, Chacinska A, Wagner K, Guiard B, Koehler CM, Rehling P, Pfanner N, Wiedemann N. Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase. EMBO Rep. 2008 Jun; 9(6):548-54. PMID: 18421298; PMCID: PMC2427372.
    50. Chen HW, Koehler CM, Teitell MA. Human polynucleotide phosphorylase: location matters. Trends Cell Biol. 2007 Dec; 17(12):600-8. PMID: 17983748.
      View in: PubMed
    51. Dabir DV, Leverich EP, Kim SK, Tsai FD, Hirasawa M, Knaff DB, Koehler CM. A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1. EMBO J. 2007 Nov 28; 26(23):4801-11. PMID: 17972915; PMCID: PMC2099471.
    52. Hwang DK, Claypool SM, Leuenberger D, Tienson HL, Koehler CM. Tim54p connects inner membrane assembly and proteolytic pathways in the mitochondrion. J Cell Biol. 2007 Sep 24; 178(7):1161-75. PMID: 17893242; PMCID: PMC2064651.
    53. Sedivá A, Smith CI, Asplund AC, Hadac J, Janda A, Zeman J, Hansíková H, Dvoráková L, Mrázová L, Velbri S, Koehler C, Roesch K, Sullivan KE, Futatani T, Ochs HD. Contiguous X-chromosome deletion syndrome encompassing the BTK, TIMM8A, TAF7L, and DRP2 genes. J Clin Immunol. 2007 Nov; 27(6):640-6. PMID: 17851739.
      View in: PubMed
    54. Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev. 2007 Apr 01; 21(7):784-96. PMID: 17374715; PMCID: PMC1838530.
    55. Stuart RA, Koehler CM. In vitro analysis of yeast mitochondrial protein import. Curr Protoc Cell Biol. 2007 Mar; Chapter 11:Unit 11.19. PMID: 18228496.
      View in: PubMed
    56. Chen HW, Rainey RN, Balatoni CE, Dawson DW, Troke JJ, Wasiak S, Hong JS, McBride HM, Koehler CM, Teitell MA, French SW. Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol. 2006 Nov; 26(22):8475-87. PMID: 16966381; PMCID: PMC1636764.
    57. Rainey RN, Glavin JD, Chen HW, French SW, Teitell MA, Koehler CM. A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space. Mol Cell Biol. 2006 Nov; 26(22):8488-97. PMID: 16966379; PMCID: PMC1636789.
    58. French SW, Dawson DW, Chen HW, Rainey RN, Sievers SA, Balatoni CE, Wong L, Troke JJ, Nguyen MT, Koehler CM, Teitell MA. The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity. Cancer Lett. 2007 Apr 18; 248(2):198-210. PMID: 16934922.
      View in: PubMed
    59. Claypool SM, McCaffery JM, Koehler CM. Mitochondrial mislocalization and altered assembly of a cluster of Barth syndrome mutant tafazzins. J Cell Biol. 2006 Jul 31; 174(3):379-90. PMID: 16880272; PMCID: PMC2064234.
    60. Koehler CM, Beverly KN, Leverich EP. Redox pathways of the mitochondrion. Antioxid Redox Signal. 2006 May-Jun; 8(5-6):813-22. PMID: 16771672.
      View in: PubMed
    61. Claypool SM, Koehler CM. Hereditary spastic paraplegia: respiratory choke or unactivated substrate? Cell. 2005 Oct 21; 123(2):183-5. PMID: 16239134.
      View in: PubMed
    62. Likic VA, Perry A, Hulett J, Derby M, Traven A, Waller RF, Keeling PJ, Koehler CM, Curran SP, Gooley PR, Lithgow T. Patterns that define the four domains conserved in known and novel isoforms of the protein import receptor Tom20. J Mol Biol. 2005 Mar 18; 347(1):81-93. PMID: 15733919.
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    63. Curran SP, Leverich EP, Koehler CM, Larsen PL. Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development. J Biol Chem. 2004 Dec 24; 279(52):54655-62. PMID: 15485840.
      View in: PubMed
    64. Curran SP, Leuenberger D, Leverich EP, Hwang DK, Beverly KN, Koehler CM. The role of Hot13p and redox chemistry in the mitochondrial TIM22 import pathway. J Biol Chem. 2004 Oct 15; 279(42):43744-51. PMID: 15294910.
      View in: PubMed
    65. Roesch K, Hynds PJ, Varga R, Tranebjaerg L, Koehler CM. The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a-TIMM13 complex. Hum Mol Genet. 2004 Sep 15; 13(18):2101-11. PMID: 15254020.
      View in: PubMed
    66. Koehler CM. New developments in mitochondrial assembly. Annu Rev Cell Dev Biol. 2004; 20:309-35. PMID: 15473843.
      View in: PubMed
    67. Koehler CM. The small Tim proteins and the twin Cx3C motif. Trends Biochem Sci. 2004 Jan; 29(1):1-4. PMID: 14729324.
      View in: PubMed
    68. van der Bliek AM, Koehler CM. A mitochondrial rhomboid protease. Dev Cell. 2003 Jun; 4(6):769-70. PMID: 12791261.
      View in: PubMed
    69. Dyall SD, Lester DC, Schneider RE, Delgadillo-Correa MG, Plümper E, Martinez A, Koehler CM, Johnson PJ. Trichomonas vaginalis Hmp35, a putative pore-forming hydrogenosomal membrane protein, can form a complex in yeast mitochondria. J Biol Chem. 2003 Aug 15; 278(33):30548-61. PMID: 12766161.
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    70. Leuenberger D, Curran SP, Wong D, Koehler CM. The role of Tim9p in the assembly of the TIM22 import complexes. Traffic. 2003 Mar; 4(3):144-52. PMID: 12656987.
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    71. Curran SP, Leuenberger D, Schmidt E, Koehler CM. The role of the Tim8p-Tim13p complex in a conserved import pathway for mitochondrial polytopic inner membrane proteins. J Cell Biol. 2002 Sep 16; 158(6):1017-27. PMID: 12221072; PMCID: PMC2173223.
    72. Curran SP, Leuenberger D, Oppliger W, Koehler CM. The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. EMBO J. 2002 Mar 01; 21(5):942-53. PMID: 11867522; PMCID: PMC125908.
    73. Roesch K, Curran SP, Tranebjaerg L, Koehler CM. Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex. Hum Mol Genet. 2002 Mar 01; 11(5):477-86. PMID: 11875042.
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