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Reed Elaine

Title(s)Professor, Pathology and Laboratory Medicine
Phone(310) 794-4943
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    Other Positions
    Title(s)Director, Immunogenetics Center


    Collapse Research 
    Collapse Research Activities and Funding
    The role of HLA and its coreceptors in endothelial cell activation and leukocyte recruitment in antibody-mediated transplant rejection
    NIH/NIAID R01AI135201Sep 1, 2018 - Aug 31, 2023
    Role: Principal Investigator
    Mapping Immune Responses to CMV in Renal Transplant Recipients
    NIH/NIAID U19AI128913Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Anti-HLA Antibody Activation of Endothelial Cells in Cardiac Transplantation
    NIH/NHLBI R01HL090995May 1, 2008 - Mar 31, 2013
    Role: Principal Investigator
    Anti-MHC Effects on Endothelium
    NIH/NIAID R56AI042819Jan 1, 1999 - Feb 29, 2016
    Role: Principal Investigator
    Anti-MHC Effects on Endothelium
    NIH/NIAID R01AI042819Jan 1, 1999 - Dec 31, 2014
    Role: Principal Investigator
    INFLUENCE OF HLA ON ANTIBODIES AND TCR V GENE EXPRESSION
    NIH/NIAID R01AI033699Sep 30, 1993 - Jun 30, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Sosa RA, Rossetti M, Naini BV, Groysberg VM, Kaldas FM, Busuttil RW, Chang YL, Gjertson DW, Kupiec-Weglinski JW, Reed EF. Pattern Recognition Receptor-reactivity Screening of Liver Transplant Patients: Potential for Personalized and Precise Organ Matching to Reduce Risks of Ischemia-reperfusion Injury. Ann Surg. 2018 Nov 22. PMID: 30480558.
      View in: PubMed
    2. Schaenman JM, Rossetti M, Sidwell T, Groysberg V, Sunga G, Liang E, Vangala S, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. Association of pro-inflammatory cytokines and monocyte subtypes in older and younger patients on clinical outcomes after mechanical circulatory support device implantation. Hum Immunol. 2018 Nov 14. PMID: 30445099.
      View in: PubMed
    3. Chan LC, Rossetti M, Miller LS, Filler SG, Johnson CW, Lee HK, Wang H, Gjertson D, Fowler VG, Reed EF, Yeaman MR. Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):E11111-E11119. PMID: 30297395.
      View in: PubMed
    4. Zhang Q, Hickey M, Drogalis-Kim D, Zheng Y, Gjertson D, Cadeiras M, Khuu T, Baas AS, Depasquale EC, Halnon NJ, Perens G, Alejos J, Cruz D, Ali N, Shemin R, Kwon M, Fishbein MC, Ardehali A, Deng M, Reed EF. Understanding the Correlation Between DSA, Complement Activation, and Antibody-Mediated Rejection in Heart Transplant Recipients. Transplantation. 2018 Oct; 102(10):e431-e438. PMID: 29916988.
      View in: PubMed
    5. Guerra MR, Rossetti M, Zhang Z, Zhou X, Whang EC, Venick RS, Marcus EA, McDiarmid SV, Farmer DG, Reed EF, Wozniak LJ. Characterization of T cell immunophenotypes in intestinal transplantation: A pilot study. Transpl Immunol. 2018 12; 51:50-57. PMID: 30243797.
      View in: PubMed
    6. Kageyama S, Hirao H, Nakamura K, Ke B, Zhang M, Ito T, Aziz A, Oncel D, Kaldas FM, Busuttil RW, Sosa RA, Reed EF, Araujo JA, Kupiec-Weglinski JW. Recipient HO-1 inducibility is essential for posttransplant hepatic HO-1 expression and graft protection: From bench-to-bedside. Am J Transplant. 2018 Jul 30. PMID: 30059195.
      View in: PubMed
    7. Bouquegneau A, Loheac C, Aubert O, Bouatou Y, Viglietti D, Empana JP, Ulloa C, Murad MH, Legendre C, Glotz D, Jackson AM, Zeevi A, Schaub S, Taupin JL, Reed EF, Friedewald JJ, Tyan DB, Süsal C, Shapiro R, Woodle ES, Hidalgo LG, O'Leary J, Montgomery RA, Kobashigawa J, Jouven X, Jabre P, Lefaucheur C, Loupy A. Correction: Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis. PLoS Med. 2018 Jul; 15(7):e1002637. PMID: 30052664.
      View in: PubMed
    8. Bouquegneau A, Loheac C, Aubert O, Bouatou Y, Viglietti D, Empana JP, Ulloa C, Murad MH, Legendre C, Glotz D, Jackson AM, Zeevi A, Schaub S, Taupin JL, Reed EF, Friedewald JJ, Tyan DB, Süsal C, Shapiro R, Woodle ES, Hidalgo LG, O'Leary J, Montgomery RA, Kobashigawa J, Jouven X, Jabre P, Lefaucheur C, Loupy A. Complement-activating donor-specific anti-HLA antibodies and solid organ transplant survival: A systematic review and meta-analysis. PLoS Med. 2018 05; 15(5):e1002572. PMID: 29799874.
      View in: PubMed
    9. Tambur AR, Campbell P, Claas FH, Feng S, Gebel HM, Jackson AM, Mannon RB, Reed EF, Tinckam K, Askar M, Chandraker A, Chang PP, Colvin M, Demetris AJ, Diamond JM, Dipchand AI, Fairchild RL, Ford ML, Friedewald J, Gill RG, Glotz D, Goldberg H, Hachem R, Knechtle S, Kobashigawa J, Levine DJ, Levitsky J, Mengel M, Milford E, Newell KA, O'Leary JG, Palmer S, Randhawa P, Smith J, Snyder L, Starling RC, Sweet S, Taner T, Taylor CJ, Woodle S, Zeevi A, Nickerson P. Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report. Am J Transplant. 2018 Jul; 18(7):1604-1614. PMID: 29603613.
      View in: PubMed
    10. Kageyama S, Nakamura K, Fujii T, Ke B, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. Recombinant relaxin protects liver transplants from ischemia damage by hepatocyte glucocorticoid receptor: From bench-to-bedside. Hepatology. 2018 07; 68(1):258-273. PMID: 29350771.
      View in: PubMed
    11. Lan JH, Gjertson D, Zheng Y, Clark S, Reed EF, Cecka MJ. Clinical utility of complement-dependent C3d assay in kidney recipients presenting with late allograft dysfunction. Am J Transplant. 2018 Dec; 18(12):2934-2944. PMID: 29659162.
      View in: PubMed
    12. Roux A, Thomas KA, Sage E, Suberbielle-Boissel C, Beaumont-Azuar L, Parquin F, Le Guen M, Harre N, Hamid AM, Reed EF. Donor-specific HLA antibody-mediated complement activation is a significant indicator of antibody-mediated rejection and poor long-term graft outcome during lung transplantation: a single center cohort study. Transpl Int. 2018 07; 31(7):761-772. PMID: 29537702.
      View in: PubMed
    13. Bakir M, Jackson NJ, Han SX, Bui A, Chang E, Liem DA, Ardehali A, Ardehali R, Baas AS, Press MC, Cruz D, Deng MC, DePasquale EC, Fonarow GC, Khuu T, Kwon MH, Kubak BM, Nsair A, Phung JL, Reed EF, Schaenman JM, Shemin RJ, Zhang QJ, Tseng CH, Cadeiras M. Clinical phenomapping and outcomes after heart transplantation. J Heart Lung Transplant. 2018 Aug; 37(8):956-966. PMID: 29802085.
      View in: PubMed
    14. Jin YP, Valenzuela NM, Zhang X, Rozengurt E, Reed EF. HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. J Immunol. 2018 Apr 01; 200(7):2372-2390. PMID: 29475988.
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    15. Liang EC, Rossetti M, Sidwell T, Groysberg V, Sunga G, Korin Y, Vangala S, Abdalla B, Lum E, Bunnapradist S, Pham PT, Danovitch G, Reed EF, Schaenman J. Differences in Proinflammatory Cytokines and Monocyte Subtypes in Older as Compared With Younger Kidney Transplant Recipients. Transplant Direct. 2018 Mar; 4(3):e348. PMID: 29707619.
      View in: PubMed
    16. Schaenman JM, Rossetti M, Korin Y, Sidwell T, Groysberg V, Liang E, Vangala S, Wisniewski N, Chang E, Bakir M, Bondar G, Cadeiras M, Kwon M, Reed EF, Deng M. T cell dysfunction and patient age are associated with poor outcomes after mechanical circulatory support device implantation. Hum Immunol. 2018 Apr; 79(4):203-212. PMID: 29409843.
      View in: PubMed
    17. Kobashigawa J, Colvin M, Potena L, Dragun D, Crespo-Leiro MG, Delgado JF, Olymbios M, Parameshwar J, Patel J, Reed E, Reinsmoen N, Rodriguez ER, Ross H, Starling RC, Tyan D, Urschel S, Zuckermann A. The management of antibodies in heart transplantation: An ISHLT consensus document. J Heart Lung Transplant. 2018 May; 37(5):537-547. PMID: 29452978.
      View in: PubMed
    18. Guerra MR, Naini BV, Scapa JV, Reed EF, Busuttil RW, Cheng EY, Farmer DG, Vargas JH, Venick RS, McDiarmid SV, Wozniak LJ. Obliterative portal venopathy: A histopathologic finding associated with chronic antibody-mediated rejection in pediatric liver allografts. Pediatr Transplant. 2018 03; 22(2). PMID: 29363222.
      View in: PubMed
    19. Reed EF, Nickerson PW. The Cutting Edge of HLA Diagnostics. Transplantation. 2018 01; 102(1):13-14. PMID: 29271868.
      View in: PubMed
    20. Valenzuela N, Soe NN, Li F, Zhang X, Jin YP, Reed EF. HLA Class I and Class II-Induced Intracellular Signaling and Molecular Associations in Primary Human Endothelial Cells. Methods Mol Biol. 2018; 1788:23-41. PMID: 28994032.
      View in: PubMed
    21. Nakamura K, Kageyama S, Yue S, Huang J, Fujii T, Ke B, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. Heme oxygenase-1 regulates sirtuin-1-autophagy pathway in liver transplantation: From mouse to human. Am J Transplant. 2018 May; 18(5):1110-1121. PMID: 29136322.
      View in: PubMed
    22. Bondar G, Togashi R, Cadeiras M, Schaenman J, Cheng RK, Masukawa L, Hai J, Bao TM, Chu D, Chang E, Bakir M, Kupiec-Weglinski S, Groysberg V, Grogan T, Meltzer J, Kwon M, Rossetti M, Elashoff D, Reed E, Ping PP, Deng MC. Association between preoperative peripheral blood mononuclear cell gene expression profiles, early postoperative organ function recovery potential and long-term survival in advanced heart failure patients undergoing mechanical circulatory support. PLoS One. 2017; 12(12):e0189420. PMID: 29236770.
      View in: PubMed
    23. Salehi S, Sosa RA, Jin YP, Kageyama S, Fishbein MC, Rozengurt E, Kupiec-Weglinski JW, Reed EF. Outside-in HLA class I signaling regulates ICAM-1 clustering and endothelial cell-monocyte interactions via mTOR in transplant antibody-mediated rejection. Am J Transplant. 2018 May; 18(5):1096-1109. PMID: 29045076.
      View in: PubMed
    24. Roedder S, Sigdel T, Hsieh SC, Cheeseman J, Metes D, Macedo C, Reed EF, Gritsch HA, Zeevi A, Shapiro R, Kirk AD, Sarwal MM. Expression of Mitochondrial-Encoded Genes in Blood Differentiate Acute Renal Allograft Rejection. Front Med (Lausanne). 2017; 4:185. PMID: 29164120.
      View in: PubMed
    25. Nakamura K, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW. Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human. Liver Transpl. 2017 10; 23(10):1282-1293. PMID: 28719070.
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    26. Pearl MH, Zhang Q, Palma Diaz MF, Grotts J, Rossetti M, Elashoff D, Gjertson DW, Weng P, Reed EF, Tsai Chambers E. Angiotensin II Type 1 receptor antibodies are associated with inflammatory cytokines and poor clinical outcomes in pediatric kidney transplantation. Kidney Int. 2018 01; 93(1):260-269. PMID: 28927645.
      View in: PubMed
    27. Nakamura K, Zhang M, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Araujo JA, Kupiec-Weglinski JW. Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury. J Hepatol. 2017 Dec; 67(6):1232-1242. PMID: 28842295.
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    28. Weng PL, Alejos JC, Halnon N, Zhang Q, Reed EF, Tsai Chambers E. Long-term outcomes of simultaneous heart and kidney transplantation in pediatric recipients. Pediatr Transplant. 2017 Nov; 21(7). PMID: 28727227.
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    29. Valenzuela NM, Thomas KA, Mulder A, Parry GC, Panicker S, Reed EF. Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003. Transplantation. 2017 07; 101(7):1559-1572. PMID: 28640789.
      View in: PubMed
    30. Valenzuela NM, Reed EF. Antibody-mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies. J Clin Invest. 2017 Jun 30; 127(7):2492-2504. PMID: 28604384.
      View in: PubMed
    31. Schaenman JM, Korin Y, Sidwell T, Kandarian F, Harre N, Gjertson D, Lum EL, Reddy U, Huang E, Pham PT, Bunnapradist S, Danovitch GM, Veale J, Gritsch HA, Reed EF. Increased Frequency of BK Virus-Specific Polyfunctional CD8+ T Cells Predict Successful Control of BK Viremia After Kidney Transplantation. Transplantation. 2017 06; 101(6):1479-1487. PMID: 27391197.
      View in: PubMed
    32. Boudreau JE, Giglio F, Gooley TA, Stevenson PA, Le Luduec JB, Shaffer BC, Rajalingam R, Hou L, Hurley CK, Noreen H, Reed EF, Yu N, Vierra-Green C, Haagenson M, Malkki M, Petersdorf EW, Spellman S, Hsu KC. KIR3DL1/ HL A-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation. J Clin Oncol. 2017 Jul 10; 35(20):2268-2278. PMID: 28520526.
      View in: PubMed
    33. Butler CL, Valenzuela NM, Thomas KA, Reed EF. Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. J Immunol Res. 2017; 2017:7903471. PMID: 28373996.
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    34. Sosa RA, Zarrinpar A, Rossetti M, Lassman CR, Naini BV, Datta N, Rao P, Harre N, Zheng Y, Spreafico R, Hoffmann A, Busuttil RW, Gjertson DW, Zhai Y, Kupiec-Weglinski JW, Reed EF. Early cytokine signatures of ischemia/reperfusion injury in human orthotopic liver transplantation. JCI Insight. 2016 12 08; 1(20):e89679. PMID: 27942590.
      View in: PubMed
    35. Hickey MJ, Zheng Y, Valenzuela N, Zhang Q, Krystal C, Lum E, Tsai EW, Lipshutz GS, Gritsch HA, Danovitch G, Veale J, Gjertson D, Cecka M, Reed EF. New priorities: Analysis of the New Kidney Allocation System on UCLA patients transplanted from the deceased donor waitlist. Hum Immunol. 2017 Jan; 78(1):41-48. PMID: 27818166.
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    36. Yin Y, Lan JH, Nguyen D, Valenzuela N, Takemura P, Bolon YT, Springer B, Saito K, Zheng Y, Hague T, Pasztor A, Horvath G, Rigo K, Reed EF, Zhang Q. Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples. PLoS One. 2016; 11(10):e0165810. PMID: 27798706.
      View in: PubMed
    37. Valenzuela NM, Hickey MJ, Reed EF. Antibody Subclass Repertoire and Graft Outcome Following Solid Organ Transplantation. Front Immunol. 2016; 7:433. PMID: 27822209.
      View in: PubMed
    38. Wozniak LJ, Naini BV, Hickey MJ, Bhattacharyya S, Reed EF, Busuttil RW, Farmer DG, Vargas JH, Venick RS, McDiarmid SV. Acute antibody-mediated rejection in ABO-compatible pediatric liver transplant recipients: case series and review of the literature. Pediatr Transplant. 2017 Feb; 21(1). PMID: 27597379.
      View in: PubMed
    39. Zhang Q, Reed EF. The importance of non-HLA antibodies in transplantation. Nat Rev Nephrol. 2016 08; 12(8):484-95. PMID: 27345243.
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    40. Pizzo HP, Ettenger RB, Gjertson DW, Reed EF, Zhang J, Gritsch HA, Tsai EW. Sirolimus and tacrolimus coefficient of variation is associated with rejection, donor-specific antibodies, and nonadherence. Pediatr Nephrol. 2016 12; 31(12):2345-2352. PMID: 27286686.
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    41. Pearl MH, Nayak AB, Ettenger RB, Puliyanda D, Palma Diaz MF, Zhang Q, Reed EF, Tsai EW. Bortezomib may stabilize pediatric renal transplant recipients with antibody-mediated rejection. Pediatr Nephrol. 2016 08; 31(8):1341-8. PMID: 27048228.
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    42. Finak G, Langweiler M, Jaimes M, Malek M, Taghiyar J, Korin Y, Raddassi K, Devine L, Obermoser G, Pekalski ML, Pontikos N, Diaz A, Heck S, Villanova F, Terrazzini N, Kern F, Qian Y, Stanton R, Wang K, Brandes A, Ramey J, Aghaeepour N, Mosmann T, Scheuermann RH, Reed E, Palucka K, Pascual V, Blomberg BB, Nestle F, Nussenblatt RB, Brinkman RR, Gottardo R, Maecker H, McCoy JP. Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium. Sci Rep. 2016 Feb 10; 6:20686. PMID: 26861911; PMCID: PMC4748244.
    43. Hickey MJ, Valenzuela NM, Reed EF. Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen. Front Immunol. 2016; 7:30. PMID: 26870045.
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    44. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Correction: Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand. PLoS One. 2015; 10(12):e0146008. PMID: 26699875; PMCID: PMC4689571.
    45. Wallace WD, Li N, Andersen CB, Arrossi AV, Askar M, Berry GJ, DeNicola MM, Neil DA, Pavlisko EN, Reed EF, Remmelink M, Weigt SS, Weynand B, Zhang JQ, Budev MM, Farver CF. Banff study of pathologic changes in lung allograft biopsy specimens with donor-specific antibodies. J Heart Lung Transplant. 2016 Jan; 35(1):40-8. PMID: 26601715.
      View in: PubMed
    46. Kim JY, Balamurugan A, Azari K, Hofmann C, Ng HL, Reed EF, McDiarmid S, Yang OO. Clonal CD8+ T Cell Persistence and Variable Gene Usage Bias in a Human Transplanted Hand. PLoS One. 2015; 10(8):e0136235. PMID: 26287728; PMCID: PMC4546120.
    47. Salehi S, Reed EF. The divergent roles of macrophages in solid organ transplantation. Curr Opin Organ Transplant. 2015 Aug; 20(4):446-53. PMID: 26154913; PMCID: PMC4520531.
    48. Reed EF. Technical and conceptual advances in histocompatibility and immunogenetics inform on mechanisms of transplant rejection and pave the way to development of novel therapies. Curr Opin Organ Transplant. 2015 Aug; 20(4):444-5. PMID: 26126199.
      View in: PubMed
    49. Wozniak LJ, Hickey MJ, Venick RS, Vargas JH, Farmer DG, Busuttil RW, McDiarmid SV, Reed EF. Donor-specific HLA Antibodies Are Associated With Late Allograft Dysfunction After Pediatric Liver Transplantation. Transplantation. 2015 Jul; 99(7):1416-22. PMID: 26038872.
      View in: PubMed
    50. Valenzuela NM, Reed EF. Antibodies to HLA Molecules Mimic Agonistic Stimulation to Trigger Vascular Cell Changes and Induce Allograft Injury. Curr Transplant Rep. 2015 Sep; 2(3):222-232. PMID: 28344919.
      View in: PubMed
    51. Pearl MH, Leuchter RK, Reed EF, Zhang Q, Ettenger RB, Tsai EW. Accelerated rejection, thrombosis, and graft failure with angiotensin II type 1 receptor antibodies. Pediatr Nephrol. 2015 Aug; 30(8):1371-4. PMID: 25956702.
      View in: PubMed
    52. Thomas KA, Valenzuela NM, Reed EF. The perfect storm: HLA antibodies, complement, Fc?Rs, and endothelium in transplant rejection. Trends Mol Med. 2015 May; 21(5):319-29. PMID: 25801125; PMCID: PMC4424065.
    53. Nayak AB, Ettenger RB, McGuire S, Lipshutz GS, Reed EF, Veale J, Tsai EW. Optimizing HLA matching in a highly sensitized pediatric patient using ABO-incompatible and paired exchange kidney transplantation. Pediatr Nephrol. 2015 May; 30(5):855-8. PMID: 25750074.
      View in: PubMed
    54. Khuu T, Cadeiras M, Wisniewski N, Reed EF, Deng MC. Reduced HLA Class II antibody response to proteasome inhibition in heart transplantation. J Heart Lung Transplant. 2015 Jun; 34(6):863-5. PMID: 25816969.
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    55. Kwon MH, Zhang JQ, Schaenman JM, Cadeiras M, Gjertson DW, Krystal CA, Laks H, Ardehali A, Deng MC, Shemin RJ, Reed EF. Characterization of ventricular assist device-mediated sensitization in the bridge-to-heart-transplantation patient. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):1161-6. PMID: 25702320.
      View in: PubMed
    56. Lan JH, Yin Y, Reed EF, Moua K, Thomas K, Zhang Q. Impact of three Illumina library construction methods on GC bias and HLA genotype calling. Hum Immunol. 2015 Mar; 76(2-3):166-75. PMID: 25543015.
      View in: PubMed
    57. Bondar G, Cadeiras M, Wisniewski N, Maque J, Chittoor J, Chang E, Bakir M, Starling C, Shahzad K, Ping P, Reed E, Deng M. Comparison of whole blood and peripheral blood mononuclear cell gene expression for evaluation of the perioperative inflammatory response in patients with advanced heart failure. PLoS One. 2014; 9(12):e115097. PMID: 25517110; PMCID: PMC4269402.
    58. Roedder S, Sigdel T, Salomonis N, Hsieh S, Dai H, Bestard O, Metes D, Zeevi A, Zeevi A, Gritsch A, Cheeseman J, Macedo C, Peddy R, Medeiros M, Vincenti F, Asher N, Salvatierra O, Shapiro R, Kirk A, Reed EF, Reed E, Sarwal MM. The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study. PLoS Med. 2014 Nov; 11(11):e1001759. PMID: 25386950; PMCID: PMC4227654.
    59. Li F, Wei J, Valenzuela NM, Lai C, Zhang Q, Gjertson D, Fishbein MC, Kobashigawa JA, Deng M, Reed EF. Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts. J Heart Lung Transplant. 2015 Apr; 34(4):580-587. PMID: 25511749; PMCID: PMC4402106.
    60. Valenzuela NM, McNamara JT, Reed EF. Antibody-mediated graft injury: complement-dependent and complement-independent mechanisms. Curr Opin Organ Transplant. 2014 Feb; 19(1):33-40. PMID: 24316758; PMCID: PMC4080796.
    61. Deng M, Cadeiras M, Reed EF. The multidimensional perspective of cardiac allograft rejection. Curr Opin Organ Transplant. 2013 Oct; 18(5):569-72. PMID: 23995374.
      View in: PubMed
    62. Reed EF, Rao P, Zhang Z, Gebel H, Bray RA, Guleria I, Lunz J, Mohanakumar T, Nickerson P, Tambur AR, Zeevi A, Heeger PS, Gjertson D. Comprehensive assessment and standardization of solid phase multiplex-bead arrays for the detection of antibodies to HLA. Am J Transplant. 2013 Jul; 13(7):1859-70. PMID: 23763485; PMCID: PMC3967448.
    63. Blumberg JM, Gritsch HA, Reed EF, Cecka JM, Lipshutz GS, Danovitch GM, McGuire S, Gjertson DW, Veale JL. Kidney paired donation in the presence of donor-specific antibodies. Kidney Int. 2013 Nov; 84(5):1009-16. PMID: 23715120; PMCID: PMC3913053.
    64. Valenzuela NM, Mulder A, Reed EF. HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging Fc?Rs. J Immunol. 2013 Jun 15; 190(12):6635-50. PMID: 23690477; PMCID: PMC3885237.
    65. Tait BD, Süsal C, Gebel HM, Nickerson PW, Zachary AA, Claas FH, Reed EF, Bray RA, Campbell P, Chapman JR, Coates PT, Colvin RB, Cozzi E, Doxiadis II, Fuggle SV, Gill J, Glotz D, Lachmann N, Mohanakumar T, Suciu-Foca N, Sumitran-Holgersson S, Tanabe K, Taylor CJ, Tyan DB, Webster A, Zeevi A, Opelz G. Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation. 2013 Jan 15; 95(1):19-47. PMID: 23238534.
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    66. DeNicola MM, Weigt SS, Belperio JA, Reed EF, Ross DJ, Wallace WD. Pathologic findings in lung allografts with anti-HLA antibodies. J Heart Lung Transplant. 2013 Mar; 32(3):326-32. PMID: 23313559; PMCID: PMC3878303.
    67. Valenzuela NM, Reed EF. Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury. Methods Mol Biol. 2013; 1034:41-70. PMID: 23775730; PMCID: PMC3879955.
    68. Vierra-Green C, Roe D, Hou L, Hurley CK, Rajalingam R, Reed E, Lebedeva T, Yu N, Stewart M, Noreen H, Hollenbach JA, Guethlein LA, Wang T, Spellman S, Maiers M. Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals. PLoS One. 2012; 7(11):e47491. PMID: 23139747; PMCID: PMC3489906.
    69. Reed EF. Mechanisms of action and effects of antibodies on the cells of the allograft. Hum Immunol. 2012 Dec; 73(12):1211-2. PMID: 23041459.
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    70. Shino MY, Weigt SS, Saggar R, Elashoff D, Derhovanessian A, Gregson AL, Saggar R, Reed EF, Kubak BM, Lynch JP, Belperio JA, Ardehali A, Ross DJ. Usefulness of immune monitoring in lung transplantation using adenosine triphosphate production in activated lymphocytes. J Heart Lung Transplant. 2012 Sep; 31(9):996-1002. PMID: 22884386; PMCID: PMC4204735.
    71. Wei F, Cheng S, Korin Y, Reed EF, Gjertson D, Ho CM, Gritsch HA, Veale J. Serum creatinine detection by a conducting-polymer-based electrochemical sensor to identify allograft dysfunction. Anal Chem. 2012 Sep 18; 84(18):7933-7. PMID: 22881369; PMCID: PMC4364383.
    72. Ziegler ME, Jin YP, Young SH, Rozengurt E, Reed EF. HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells. Am J Physiol Cell Physiol. 2012 Oct 15; 303(8):C872-82. PMID: 22914643; PMCID: PMC3469712.
    73. Zhang X, Valenzuela NM, Reed EF. HLA class I antibody-mediated endothelial and smooth muscle cell activation. Curr Opin Organ Transplant. 2012 Aug; 17(4):446-51. PMID: 22710387; PMCID: PMC3880156.
    74. Zhang X, Reed EF. HLA class I: an unexpected role in integrin ß4 signaling in endothelial cells. Hum Immunol. 2012 Dec; 73(12):1239-44. PMID: 22789625; PMCID: PMC3485417.
    75. Ziegler ME, Souda P, Jin YP, Whitelegge JP, Reed EF. Characterization of the endothelial cell cytoskeleton following HLA class I ligation. PLoS One. 2012; 7(1):e29472. PMID: 22247778; PMCID: PMC3256144.
    76. Patel J, Everly M, Chang D, Kittleson M, Reed E, Kobashigawa J. Reduction of alloantibodies via proteasome inhibition in cardiac transplantation. J Heart Lung Transplant. 2011 Dec; 30(12):1320-6. PMID: 21968130.
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    77. Li F, Zhang X, Jin YP, Mulder A, Reed EF. Antibody ligation of human leukocyte antigen class I molecules stimulates migration and proliferation of smooth muscle cells in a focal adhesion kinase-dependent manner. Hum Immunol. 2011 Dec; 72(12):1150-9. PMID: 22001078; PMCID: PMC3563264.
    78. Ziegler ME, Chen T, LeBlanc JF, Wei X, Gjertson DW, Li KC, Khalighi MA, Lassman CR, Veale JL, Gritsch HA, Reed EF. Apolipoprotein A1 and C-terminal fragment of a-1 antichymotrypsin are candidate plasma biomarkers associated with acute renal allograft rejection. Transplantation. 2011 Aug 27; 92(4):388-95. PMID: 21730889; PMCID: PMC3878300.
    79. Valenzuela NM, Reed EF. The link between major histocompatibility complex antibodies and cell proliferation. Transplant Rev (Orlando). 2011 Oct; 25(4):154-66. PMID: 21803559; PMCID: PMC3177030.
    80. Zhang Q, Cecka JM, Gjertson DW, Ge P, Rose ML, Patel JK, Ardehali A, Kobashigawa JA, Fishbein MC, Reed EF. HLA and MICA: targets of antibody-mediated rejection in heart transplantation. Transplantation. 2011 May 27; 91(10):1153-8. PMID: 21544036; PMCID: PMC3563270.
    81. Yang OO, Lewis MJ, Reed EF, Gjertson DW, Kalilani-Phiri L, Mkandawire J, Helleringer S, Kohler HP. Human leukocyte antigen class I haplotypes of human immunodeficiency virus-1-infected persons on Likoma Island, Malawi. Hum Immunol. 2011 Oct; 72(10):877-80. PMID: 21663781; PMCID: PMC3175254.
    82. Lipshutz GS, McGuire S, Zhu Q, Ziman A, Davis R, Goldfinger D, Reed EF, Wilkinson AH, Danovitch GM, Pham PT. ABO blood type-incompatible kidney transplantation and access to organs. Arch Surg. 2011 Apr; 146(4):453-8. PMID: 21502455.
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    83. Kobashigawa J, Crespo-Leiro MG, Ensminger SM, Reichenspurner H, Angelini A, Berry G, Burke M, Czer L, Hiemann N, Kfoury AG, Mancini D, Mohacsi P, Patel J, Pereira N, Platt JL, Reed EF, Reinsmoen N, Rodriguez ER, Rose ML, Russell SD, Starling R, Suciu-Foca N, Tallaj J, Taylor DO, Van Bakel A, West L, Zeevi A, Zuckermann A. Report from a consensus conference on antibody-mediated rejection in heart transplantation. J Heart Lung Transplant. 2011 Mar; 30(3):252-69. PMID: 21300295; PMCID: PMC3829685.
    84. Narayan S, Tsai EW, Zhang Q, Wallace WD, Reed EF, Ettenger RB. Acute rejection associated with donor-specific anti-MICA antibody in a highly sensitized pediatric renal transplant recipient. Pediatr Transplant. 2011 Feb; 15(1):E1-7. PMID: 21199204; PMCID: PMC3878296.
    85. Zhang X, Rozengurt E, Reed EF. HLA class I molecules partner with integrin ß4 to stimulate endothelial cell proliferation and migration. Sci Signal. 2010 Nov 23; 3(149):ra85. PMID: 21098729; PMCID: PMC3878299.
    86. Shah GJ, Veale JL, Korin Y, Reed EF, Gritsch HA, Kim CJ. Specific binding and magnetic concentration of CD8+ T-lymphocytes on electrowetting-on-dielectric platform. Biomicrofluidics. 2010 Nov 10; 4(4):44106. PMID: 21139700; PMCID: PMC2998035.
    87. Maecker HT, McCoy JP, Amos M, Elliott J, Gaigalas A, Wang L, Aranda R, Banchereau J, Boshoff C, Braun J, Korin Y, Reed E, Cho J, Hafler D, Davis M, Fathman CG, Robinson W, Denny T, Weinhold K, Desai B, Diamond B, Gregersen P, Di Meglio P, DiMeglio P, Nestle FO, Nestle F, Peakman M, Villanova F, Villnova F, Ferbas J, Field E, Kantor A, Kawabata T, Komocsar W, Lotze M, Nepom J, Ochs H, O'Lone R, Phippard D, Plevy S, Rich S, Roederer M, Rotrosen D, Yeh JH. A model for harmonizing flow cytometry in clinical trials. Nat Immunol. 2010 Nov; 11(11):975-8. PMID: 20959798.
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    88. Tsai EW, Wallace WD, Gjertson DW, Reed EF, Ettenger RB. Significance of intragraft CD138+ lymphocytes and p-S6RP in pediatric kidney transplant biopsies. Transplantation. 2010 Oct 27; 90(8):875-81. PMID: 20736897; PMCID: PMC2959153.
    89. Kobashigawa JA, Patel JK, Kittleson MM, Kawano MA, Kiyosaki KK, Davis SN, Moriguchi JD, Reed EF, Ardehali AA. The long-term outcome of treated sensitized patients who undergo heart transplantation. Clin Transplant. 2011 Jan-Feb; 25(1):E61-7. PMID: 20973825; PMCID: PMC3829691.
    90. Zhang Q, Reed EF. Non-MHC antigenic targets of the humoral immune response in transplantation. Curr Opin Immunol. 2010 Oct; 22(5):682-8. PMID: 20833523; PMCID: PMC2967651.
    91. Bonagura VR, Du Z, Ashouri E, Luo L, Hatam LJ, DeVoti JA, Rosenthal DW, Steinberg BM, Abramson AL, Gjertson DW, Reed EF, Rajalingam R. Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis. Hum Immunol. 2010 Feb; 71(2):212-9. PMID: 19861144; PMCID: PMC2815039.
    92. Li F, Atz ME, Reed EF. Human leukocyte antigen antibodies in chronic transplant vasculopathy-mechanisms and pathways. Curr Opin Immunol. 2009 Oct; 21(5):557-62. PMID: 19748769; PMCID: PMC2761494.
    93. Ashouri E, Farjadian S, Reed EF, Ghaderi A, Rajalingam R. KIR gene content diversity in four Iranian populations. Immunogenetics. 2009 Jul; 61(7):483-92. PMID: 19521696; PMCID: PMC2706385.
    94. Wu GW, Kobashigawa JA, Fishbein MC, Patel JK, Kittleson MM, Reed EF, Kiyosaki KK, Ardehali A. Asymptomatic antibody-mediated rejection after heart transplantation predicts poor outcomes. J Heart Lung Transplant. 2009 May; 28(5):417-22. PMID: 19416767; PMCID: PMC3829690.
    95. Sehl ME, Langer LR, Papp JC, Kwan L, Seldon JL, Arellano G, Reiss J, Reed EF, Dandekar S, Korin Y, Sinsheimer JS, Zhang ZF, Ganz PA. Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer. Clin Cancer Res. 2009 Mar 15; 15(6):2192-203. PMID: 19276285.
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    96. Kobashigawa J, Mehra M, West L, Kerman R, George J, Rose M, Zeevi A, Reinsmoen N, Patel J, Reed EF. Report from a consensus conference on the sensitized patient awaiting heart transplantation. J Heart Lung Transplant. 2009 Mar; 28(3):213-25. PMID: 19285611; PMCID: PMC3878294.
    97. Li X, Quigg RJ, Zhou J, Gu W, Nagesh Rao P, Reed EF. Clinical utility of microarrays: current status, existing challenges and future outlook. Curr Genomics. 2008 Nov; 9(7):466-74. PMID: 19506735.
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    98. Levinson RD, Du Z, Luo L, Holland GN, Rao NA, Reed EF, Rajalingam R. KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease. Hum Immunol. 2008 Jun; 69(6):349-53. PMID: 18571006.
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    99. Rajalingam R, Du Z, Meenagh A, Luo L, Kavitha VJ, Pavithra-Arulvani R, Vidhyalakshmi A, Sharma SK, Balazs I, Reed EF, Pitchappan RM, Middleton D. Distinct diversity of KIR genes in three southern Indian populations: comparison with world populations revealed a link between KIR gene content and pre-historic human migrations. Immunogenetics. 2008 May; 60(5):207-17. PMID: 18369612.
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    100. Jindra PT, Jin YP, Jacamo R, Rozengurt E, Reed EF. MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway. Biochem Biophys Res Commun. 2008 May 02; 369(2):781-7. PMID: 18312854; PMCID: PMC2376207.
    101. Jindra PT, Jin YP, Rozengurt E, Reed EF. HLA class I antibody-mediated endothelial cell proliferation via the mTOR pathway. J Immunol. 2008 Feb 15; 180(4):2357-66. PMID: 18250445.
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    102. Jindra PT, Hsueh A, Hong L, Gjertson D, Shen XD, Gao F, Dang J, Mischel PS, Baldwin WM, Fishbein MC, Kupiec-Weglinski JW, Reed EF. Anti-MHC class I antibody activation of proliferation and survival signaling in murine cardiac allografts. J Immunol. 2008 Feb 15; 180(4):2214-24. PMID: 18250428; PMCID: PMC3883756.
    103. Atz ME, Reed EF. Role of anti-MHC class I antibody in facilitating transplant accommodation. Crit Rev Immunol. 2008; 28(6):485-511. PMID: 19265506.
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    104. Stewart S, Fishbein MC, Snell GI, Berry GJ, Boehler A, Burke MM, Glanville A, Gould FK, Magro C, Marboe CC, McNeil KD, Reed EF, Reinsmoen NL, Scott JP, Studer SM, Tazelaar HD, Wallwork JL, Westall G, Zamora MR, Zeevi A, Yousem SA. Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection. J Heart Lung Transplant. 2007 Dec; 26(12):1229-42. PMID: 18096473.
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    105. Lin J, Ziring D, Desai S, Kim S, Wong M, Korin Y, Braun J, Reed E, Gjertson D, Singh RR. TNFalpha blockade in human diseases: an overview of efficacy and safety. Clin Immunol. 2008 Jan; 126(1):13-30. PMID: 17916445; PMCID: PMC2291511.
    106. Wong M, Ziring D, Korin Y, Desai S, Kim S, Lin J, Gjertson D, Braun J, Reed E, Singh RR. TNFalpha blockade in human diseases: mechanisms and future directions. Clin Immunol. 2008 Feb; 126(2):121-36. PMID: 17916444; PMCID: PMC2291518.
    107. Luo L, Du Z, Sharma SK, Cullen R, Spellman S, Reed EF, Rajalingam R. Chain-terminating natural mutations affect the function of activating KIR receptors 3DS1 and 2DS3. Immunogenetics. 2007 Oct; 59(10):779-92. PMID: 17646980.
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    108. Jin YP, Korin Y, Zhang X, Jindra PT, Rozengurt E, Reed EF. RNA interference elucidates the role of focal adhesion kinase in HLA class I-mediated focal adhesion complex formation and proliferation in human endothelial cells. J Immunol. 2007 Jun 15; 178(12):7911-22. PMID: 17548629.
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    109. Cano P, Klitz W, Mack SJ, Maiers M, Marsh SG, Noreen H, Reed EF, Senitzer D, Setterholm M, Smith A, Fernández-Viña M. Common and well-documented HLA alleles: report of the Ad-Hoc committee of the american society for histocompatiblity and immunogenetics. Hum Immunol. 2007 May; 68(5):392-417. PMID: 17462507.
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    110. Casarez TW, Perens G, Williams RJ, Kutay E, Fishbein MC, Reed EF, Alejos JC, Levi DS. Humoral rejection in pediatric orthotopic heart transplantation. J Heart Lung Transplant. 2007 Feb; 26(2):114-9. PMID: 17258143.
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    111. Tsai EW, Rianthavorn P, Gjertson DW, Wallace WD, Reed EF, Ettenger RB. CD20+ lymphocytes in renal allografts are associated with poor graft survival in pediatric patients. Transplantation. 2006 Dec 27; 82(12):1769-73. PMID: 17198274.
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    112. Du Z, Gjertson DW, Reed EF, Rajalingam R. Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans. Immunogenetics. 2007 Jan; 59(1):1-15. PMID: 17103212.
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    113. Kowalski RJ, Post DR, Mannon RB, Sebastian A, Wright HI, Sigle G, Burdick J, Elmagd KA, Zeevi A, Lopez-Cepero M, Daller JA, Gritsch HA, Reed EF, Jonsson J, Hawkins D, Britz JA. Assessing relative risks of infection and rejection: a meta-analysis using an immune function assay. Transplantation. 2006 Sep 15; 82(5):663-8. PMID: 16969290.
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    114. Palmer CG, Hsieh HJ, Reed EF, Lonnqvist J, Peltonen L, Woodward JA, Sinsheimer JS. HLA-B maternal-fetal genotype matching increases risk of schizophrenia. Am J Hum Genet. 2006 Oct; 79(4):710-5. PMID: 16960807; PMCID: PMC1592576.
    115. Veale JL, Liang LW, Zhang Q, Gjertson DW, Du Z, Bloomquist EW, Jia J, Qian L, Wilkinson AH, Danovitch GM, Pham PT, Rosenthal JT, Lassman CR, Braun J, Reed EF, Gritsch HA. Noninvasive diagnosis of cellular and antibody-mediated rejection by perforin and granzyme B in renal allografts. Hum Immunol. 2006 Oct; 67(10):777-86. PMID: 17055354.
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    116. Jindra PT, Zhang X, Mulder A, Claas F, Veale J, Jin YP, Reed EF. Anti-HLA antibodies can induce endothelial cell survival or proliferation depending on their concentration. Transplantation. 2006 Jul 15; 82(1 Suppl):S33-5. PMID: 16829793.
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    117. Khanna D, Wu H, Park G, Gersuk V, Gold RH, Nepom GT, Wong WK, Sharp JT, Reed EF, Paulus HE, Tsao BP. Association of tumor necrosis factor alpha polymorphism, but not the shared epitope, with increased radiographic progression in a seropositive rheumatoid arthritis inception cohort. Arthritis Rheum. 2006 Apr; 54(4):1105-16. PMID: 16572445.
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    118. Zhang Q, Reed EF. Array-based methods for diagnosis and prevention of transplant rejection. Expert Rev Mol Diagn. 2006 Mar; 6(2):165-78. PMID: 16512777.
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    119. Reed EF, Demetris AJ, Hammond E, Itescu S, Kobashigawa JA, Reinsmoen NL, Rodriguez ER, Rose M, Stewart S, Suciu-Foca N, Zeevi A, Fishbein MC. Acute antibody-mediated rejection of cardiac transplants. J Heart Lung Transplant. 2006 Feb; 25(2):153-9. PMID: 16446213.
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    120. Korin YD, Lee C, Gjertson DW, Wilkinson AH, Pham TP, Danovitch GM, Gritsch HA, Reed EF. A novel flow assay for the detection of cytokine secreting alloreactive T cells: application to immune monitoring. Hum Immunol. 2005 Nov; 66(11):1110-24. PMID: 16571412.
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    121. Wallace WD, Reed EF, Ross D, Lassman CR, Fishbein MC. C4d staining of pulmonary allograft biopsies: an immunoperoxidase study. J Heart Lung Transplant. 2005 Oct; 24(10):1565-70. PMID: 16210131.
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    122. Stewart S, Winters GL, Fishbein MC, Tazelaar HD, Kobashigawa J, Abrams J, Andersen CB, Angelini A, Berry GJ, Burke MM, Demetris AJ, Hammond E, Itescu S, Marboe CC, McManus B, Reed EF, Reinsmoen NL, Rodriguez ER, Rose AG, Rose M, Suciu-Focia N, Zeevi A, Billingham ME. Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant. 2005 Nov; 24(11):1710-20. PMID: 16297770.
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    123. Cecka JM, Zhang Q, Reed EF. Preformed cytotoxic antibodies in potential allograft recipients: recent data. Hum Immunol. 2005 Apr; 66(4):343-9. PMID: 15866696.
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    124. Zhang Q, Liang LW, Gjertson DW, Lassman C, Wilkinson AH, Kendrick E, Pham PT, Danovitch GM, Gritsch HA, Reed EF. Development of posttransplant antidonor HLA antibodies is associated with acute humoral rejection and early graft dysfunction. Transplantation. 2005 Mar 15; 79(5):591-8. PMID: 15753849.
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    125. Jin YP, Jindra PT, Gong KW, Lepin EJ, Reed EF. Anti-HLA class I antibodies activate endothelial cells and promote chronic rejection. Transplantation. 2005 Feb 15; 79(3 Suppl):S19-21. PMID: 15699739.
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    126. Levinson RD, See RF, Rajalingam R, Reed EF, Park MS, Rao NA, Holland GN. HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California. Hum Immunol. 2004 Dec; 65(12):1477-82. PMID: 15603876.
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    127. Lepin EJ, Jin YP, Barwe SP, Rozengurt E, Reed EF. HLA class I signal transduction is dependent on Rho GTPase and ROK. Biochem Biophys Res Commun. 2004 Oct 08; 323(1):213-7. PMID: 15351723.
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    128. Levinson RD, Rajalingam R, Park MS, Reed EF, Gjertson DW, Kappel PJ, See RF, Rao NA, Holland GN. Human leukocyte antigen A29 subtypes associated with birdshot retinochoroidopathy. Am J Ophthalmol. 2004 Oct; 138(4):631-4. PMID: 15488792.
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    129. Bonagura VR, Vambutas A, DeVoti JA, Rosenthal DW, Steinberg BM, Abramson AL, Shikowitz MJ, Gjertson DW, Reed EF. HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosis. Hum Immunol. 2004 Aug; 65(8):773-82. PMID: 15336778.
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    130. Rajalingam R, Ge P, Reed EF. A sequencing-based typing method for HLA-DQA1 alleles. Hum Immunol. 2004 Apr; 65(4):373-9. PMID: 15120193.
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    131. Jin YP, Fishbein MC, Said JW, Jindra PT, Rajalingam R, Rozengurt E, Reed EF. Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells. Hum Immunol. 2004 Apr; 65(4):291-302. PMID: 15120184.
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    132. Vambutas A, Bonagura VR, Reed EF, Abramson AL, Mullooly V, DeVoti J, Gjertson DW, Steinberg BM. Polymorphism of transporter associated with antigen presentation 1 as a potential determinant for severity of disease in recurrent respiratory papillomatosis caused by human papillomavirus types 6 and 11. J Infect Dis. 2004 Mar 01; 189(5):871-9. PMID: 14976605.
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    133. Levinson RD, Park MS, Rikkers SM, Reed EF, Smith JR, Martin TM, Rosenbaum JT, Foster CS, Sherman MD, Holland GN. Strong associations between specific HLA-DQ and HLA-DR alleles and the tubulointerstitial nephritis and uveitis syndrome. Invest Ophthalmol Vis Sci. 2003 Feb; 44(2):653-7. PMID: 12556395.
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    134. Michaels PJ, Espejo ML, Kobashigawa J, Alejos JC, Burch C, Takemoto S, Reed EF, Fishbein MC. Humoral rejection in cardiac transplantation: risk factors, hemodynamic consequences and relationship to transplant coronary artery disease. J Heart Lung Transplant. 2003 Jan; 22(1):58-69. PMID: 12531414.
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    135. Reed EF. Signal transduction via MHC class I molecules in endothelial and smooth muscle cells. Crit Rev Immunol. 2003; 23(1-2):109-28. PMID: 12906262.
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    136. Jin YP, Singh RP, Du ZY, Rajasekaran AK, Rozengurt E, Reed EF. Ligation of HLA class I molecules on endothelial cells induces phosphorylation of Src, paxillin, and focal adhesion kinase in an actin-dependent manner. J Immunol. 2002 Jun 01; 168(11):5415-23. PMID: 12023334.
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