Eskin Eleazar

TitleAssociate Professor
InstitutionUniversity of California Los Angeles
DepartmentComputer Science
Address3532-J Boelter Hall
Los Angeles CA 90095
Phone(310) 206-4490
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    Other Positions
    TitleAssociate Professor

    Collapse Research 
    Collapse Research Activities and Funding
    Genetic pathways for impulsivity and drug reinforcement: DNA and transcriptome variation in mice
    NIH/NIDA U01DA041602Sep 15, 2017 - May 31, 2022
    Role: Co-Principal Investigator
    Undergraduate Research Experience in Neuropsychiatric Genomics
    NIH/NIMH R25MH109172Feb 1, 2016 - Nov 30, 2020
    Role: Co-Principal Investigator
    Mathematical and Computational Approaches in High-Throughput Genomics Training
    NIH/NIGMS R25GM112625Sep 1, 2015 - Jun 30, 2020
    Role: Principal Investigator
    Correcting for Population Structure in Gene-by-Environment Interaction Studies
    NIH/NIEHS R01ES022282Sep 1, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Discovering the Genetic Basis of Hypertension
    NIH/NHLBI K25HL080079Jun 1, 2006 - May 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Gai L, Eskin E. Finding associated variants in genome-wide association studies on multiple traits. Bioinformatics. 2018 Jul 01; 34(13):i467-i474. PMID: 29949991.
      View in: PubMed
    2. Gamazon ER, Segrè AV, van de Bunt M, Wen X, Xi HS, Hormozdiari F, Ongen H, Konkashbaev A, Derks EM, Aguet F, Quan J, Nicolae DL, Eskin E, Kellis M, Getz G, McCarthy MI, Dermitzakis ET, Cox NJ, Ardlie KG. Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation. Nat Genet. 2018 Jun 28. PMID: 29955180.
      View in: PubMed
    3. Hormozdiari F, Gazal S, van de Geijn B, Finucane HK, Ju CJ, Loh PR, Schoech A, Reshef Y, Liu X, O'Connor L, Gusev A, Eskin E, Price AL. Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Nat Genet. 2018 Jun 25. PMID: 29942083.
      View in: PubMed
    4. Kennedy EM, Goehring GN, Nichols MH, Robins C, Mehta D, Klengel T, Eskin E, Smith AK, Conneely KN. An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells. BMC Genomics. 2018 Jun 19; 19(1):476. PMID: 29914364.
      View in: PubMed
    5. Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. 2018 May 11. PMID: 29752291.
      View in: PubMed
    6. Olde Loohuis LM, Mangul S, Ori APS, Jospin G, Koslicki D, Yang HT, Wu T, Boks MP, Lomen-Hoerth C, Wiedau-Pazos M, Cantor RM, de Vos WM, Kahn RS, Eskin E, Ophoff RA. Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia. Transl Psychiatry. 2018 May 10; 8(1):96. PMID: 29743478.
      View in: PubMed
    7. Mangul S, Martin LS, Eskin E. Involving undergraduates in genomics research to narrow the education-research gap. Nat Biotechnol. 2018 Apr 05; 36(4):369-371. PMID: 29621227.
      View in: PubMed
    8. Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, Ophoff RA, Santana JR, Levanon EY, Woodruff PG, Burchard E, Seibold MA, Shifman S, Eskin E, Zaitlen N. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biol. 2018 Feb 15; 19(1):36. PMID: 29548336.
      View in: PubMed
    9. Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. An ancestry-based approach for detecting interactions. Genet Epidemiol. 2018 02; 42(1):49-63. PMID: 29114909.
      View in: PubMed
    10. Jasinska AJ, Zelaya I, Service SK, Peterson CB, Cantor RM, Choi OW, DeYoung J, Eskin E, Fairbanks LA, Fears S, Furterer AE, Huang YS, Ramensky V, Schmitt CA, Svardal H, Jorgensen MJ, Kaplan JR, Villar D, Aken BL, Flicek P, Nag R, Wong ES, Blangero J, Dyer TD, Bogomolov M, Benjamini Y, Weinstock GM, Dewar K, Sabatti C, Wilson RK, Jentsch JD, Warren W, Coppola G, Woods RP, Freimer NB. Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate. Nat Genet. 2017 Dec; 49(12):1714-1721. PMID: 29083405.
      View in: PubMed
    11. Crawford NG, Kelly DE, Hansen MEB, Beltrame MH, Fan S, Bowman SL, Jewett E, Ranciaro A, Thompson S, Lo Y, Pfeifer SP, Jensen JD, Campbell MC, Beggs W, Hormozdiari F, Mpoloka SW, Mokone GG, Nyambo T, Meskel DW, Belay G, Haut J, Rothschild H, Zon L, Zhou Y, Kovacs MA, Xu M, Zhang T, Bishop K, Sinclair J, Rivas C, Elliot E, Choi J, Li SA, Hicks B, Burgess S, Abnet C, Watkins-Chow DE, Oceana E, Song YS, Eskin E, Brown KM, Marks MS, Loftus SK, Pavan WJ, Yeager M, Chanock S, Tishkoff SA. Loci associated with skin pigmentation identified in African populations. Science. 2017 11 17; 358(6365). PMID: 29025994.
      View in: PubMed
    12. Ritchie MD, Davis JR, Aschard H, Battle A, Conti D, Du M, Eskin E, Fallin MD, Hsu L, Kraft P, Moore JH, Pierce BL, Bien SA, Thomas DC, Wei P, Montgomery SB. Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. Am J Epidemiol. 2017 Oct 01; 186(7):771-777. PMID: 28978191.
      View in: PubMed
    13. Mangul S, Martin LS, Hoffmann A, Pellegrini M, Eskin E. Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX. Trends Biotechnol. 2017 10; 35(10):901-903. PMID: 28720283.
      View in: PubMed
    14. Duong D, Gai L, Snir S, Kang EY, Han B, Sul JH, Eskin E. Applying meta-analysis to genotype-tissue expression data from multiple tissues to identify eQTLs and increase the number of eGenes. Bioinformatics. 2017 Jul 15; 33(14):i67-i74. PMID: 28881962.
      View in: PubMed
    15. Buckley MT, Racimo F, Allentoft ME, Jensen MK, Jonsson A, Huang H, Hormozdiari F, Sikora M, Marnetto D, Eskin E, Jørgensen ME, Grarup N, Pedersen O, Hansen T, Kraft P, Willerslev E, Nielsen R. Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes. Mol Biol Evol. 2017 Jun 01; 34(6):1307-1318. PMID: 28333262.
      View in: PubMed
    16. Hormozdiari F, Zhu A, Kichaev G, Ju CJ, Segrè AV, Joo JWJ, Won H, Sankararaman S, Pasaniuc B, Shifman S, Eskin E. Widespread Allelic Heterogeneity in Complex Traits. Am J Hum Genet. 2017 May 04; 100(5):789-802. PMID: 28475861.
      View in: PubMed
    17. He D, Wang Z, Parida L, Eskin E. IPED2: Inheritance Path Based Pedigree Reconstruction Algorithm for Complicated Pedigrees. IEEE/ACM Trans Comput Biol Bioinform. 2017 Sep-Oct; 14(5):1094-1103. PMID: 28368828.
      View in: PubMed
    18. Mangul S, Yang TH, Hormozdiari F, Dainis AM, Tseng E, Ashley EA, Zelikovsky A, Eskin E. HapIso: An Accurate Method for the Haplotype- Specific Isoforms Reconstruction From Long Single-Molecule Reads. IEEE Trans Nanobioscience. 2017 03; 16(2):108-115. PMID: 28328508.
      View in: PubMed
    19. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nat Methods. 2017 02 28; 14(3):218-219. PMID: 28245214.
      View in: PubMed
    20. Bilow M, Crespo F, Pan Z, Eskin E, Eyheramendy S. Simultaneous Modeling of Disease Status and Clinical Phenotypes To Increase Power in Genome-Wide Association Studies. Genetics. 2017 03; 205(3):1041-1047. PMID: 28132020.
      View in: PubMed
    21. Artyomenko A, Wu NC, Mangul S, Eskin E, Sun R, Zelikovsky A. Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants. J Comput Biol. 2017 Jun; 24(6):558-570. PMID: 27901586.
      View in: PubMed
    22. Hormozdiari F, van de Bunt M, Segrè AV, Li X, Joo JWJ, Bilow M, Sul JH, Sankararaman S, Pasaniuc B, Eskin E. Colocalization of GWAS and eQTL Signals Detects Target Genes. Am J Hum Genet. 2016 Dec 01; 99(6):1245-1260. PMID: 27866706.
      View in: PubMed
    23. Joo JW, Kang EY, Org E, Furlotte N, Parks B, Hormozdiari F, Lusis AJ, Eskin E. Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure. Genetics. 2016 Dec; 204(4):1379-1390. PMID: 27770036.
      View in: PubMed
    24. Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. 2016 10 27; 538(7626):523-527. PMID: 27760116.
      View in: PubMed
    25. Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda). 2016 10 13; 6(10):3219-3228. PMID: 27520957.
      View in: PubMed
    26. Kang EY, Martin LJ, Mangul S, Isvilanonda W, Zou J, Ben-David E, Han B, Lusis AJ, Shifman S, Eskin E. Discovering Single Nucleotide Polymorphisms Regulating Human Gene Expression Using Allele Specific Expression from RNA-seq Data. Genetics. 2016 11; 204(3):1057-1064. PMID: 27765809.
      View in: PubMed
    27. Kichaev G, Roytman M, Johnson R, Eskin E, Lindström S, Kraft P, Pasaniuc B. Improved methods for multi-trait fine mapping of pleiotropic risk loci. Bioinformatics. 2017 01 15; 33(2):248-255. PMID: 27663501.
      View in: PubMed
    28. Main BJ, Lee Y, Ferguson HM, Kreppel KS, Kihonda A, Govella NJ, Collier TC, Cornel AJ, Eskin E, Kang EY, Nieman CC, Weakley AM, Lanzaro GC. The Genetic Basis of Host Preference and Resting Behavior in the Major African Malaria Vector, Anopheles arabiensis. PLoS Genet. 2016 Sep; 12(9):e1006303. PMID: 27631375; PMCID: PMC5025075.
    29. Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Brümmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife. 2016 09 13; 5. PMID: 27623010.
      View in: PubMed
    30. Kang EY, Park Y, Li X, Segrè AV, Han B, Eskin E. ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. G3 (Bethesda). 2016 07 07; 6(7):1793-8. PMID: 27194809; PMCID: PMC4938634.
    31. Duong D, Zou J, Hormozdiari F, Sul JH, Ernst J, Han B, Eskin E. Using genomic annotations increases statistical power to detect eGenes. Bioinformatics. 2016 06 15; 32(12):i156-i163. PMID: 27307612; PMCID: PMC4908356.
    32. Hormozdiari F, Kang EY, Bilow M, Ben-David E, Vulpe C, McLachlan S, Lusis AJ, Han B, Eskin E. Imputing Phenotypes for Genome-wide Association Studies. Am J Hum Genet. 2016 Jul 07; 99(1):89-103. PMID: 27292110; PMCID: PMC5005435 [Available on 01/07/17].
    33. Schweiger R, Kaufman S, Laaksonen R, Kleber ME, März W, Eskin E, Rosset S, Halperin E. Fast and Accurate Construction of Confidence Intervals for Heritability. Am J Hum Genet. 2016 06 02; 98(6):1181-1192. PMID: 27259052.
      View in: PubMed
    34. Peterson CB, Service SK, Jasinska AJ, Gao F, Zelaya I, Teshiba TM, Bearden CE, Cantor RM, Reus VI, Macaya G, López-Jaramillo C, Bogomolov M, Benjamini Y, Eskin E, Coppola G, Freimer NB, Sabatti C. Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder. PLoS Genet. 2016 May; 12(5):e1006046. PMID: 27176483; PMCID: PMC4866754.
    35. Lusis AJ, Seldin MM, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber CR, Hui S, Mehrabian M, Norheim F, Pan C, Parks B, Rau CD, Smith DJ, Vallim T, Wang Y, Wang J. The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res. 2016 06; 57(6):925-42. PMID: 27099397; PMCID: PMC4878195 [Available on 06/01/17].
    36. Joo JW, Hormozdiari F, Han B, Eskin E. Multiple testing correction in linear mixed models. Genome Biol. 2016 Apr 01; 17:62. PMID: 27039378; PMCID: PMC4818520.
    37. Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nat Methods. 2016 05; 13(5):443-5. PMID: 27018579.
      View in: PubMed
    38. Sul JH, Bilow M, Yang WY, Kostem E, Furlotte N, He D, Eskin E. Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models. PLoS Genet. 2016 Mar; 12(3):e1005849. PMID: 26943367; PMCID: PMC4778803.
    39. Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Sevag Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ. Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. PLoS Genet. 2016 Mar; 12(3):e1005913. PMID: 26934746; PMCID: PMC4775237.
    40. Han B, Duong D, Sul JH, de Bakker PI, Eskin E, Raychaudhuri S. A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping. Hum Mol Genet. 2016 05 01; 25(9):1857-66. PMID: 26908615; PMCID: PMC4986332 [Available on 05/01/17].
    41. Bennett BJ, Davis RC, Civelek M, Orozco L, Wu J, Qi H, Pan C, Packard RR, Eskin E, Yan M, Kirchgessner T, Wang Z, Li X, Gregory JC, Hazen SL, Gargalovic PS, Lusis AJ. Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains. PLoS Genet. 2015 Dec; 11(12):e1005711. PMID: 26694027; PMCID: PMC4687930.
    42. Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants. G3 (Bethesda). 2015 Sep 04; 5(11):2329-39. PMID: 26342000; PMCID: PMC4632053.
    43. Org E, Parks BW, Joo JW, Emert B, Schwartzman W, Kang EY, Mehrabian M, Pan C, Knight R, Gunsalus R, Drake TA, Eskin E, Lusis AJ. Genetic and environmental control of host-gut microbiota interactions. Genome Res. 2015 Oct; 25(10):1558-69. PMID: 26260972; PMCID: PMC4579341.
    44. Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ. High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. G3 (Bethesda). 2015 Jul 28; 5(10):2021-6. PMID: 26224782; PMCID: PMC4592984.
    45. Nanda V, Gutman B, Bar E, Alghamdi S, Tetradis S, Lusis AJ, Eskin E, Moon W. Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application. Prog Orthod. 2015; 16:21. PMID: 26133934; PMCID: PMC4488234.
    46. Hormozdiari F, Kichaev G, Yang WY, Pasaniuc B, Eskin E. Identification of causal genes for complex traits. Bioinformatics. 2015 Jun 15; 31(12):i206-13. PMID: 26072484; PMCID: PMC4542778.
    47. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss. PLoS Genet. 2015 Jun; 11(6):e1005293. PMID: 26068505; PMCID: PMC4465750.
    48. Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BJ, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. 2015 Jul 14; 5(1):125-38. PMID: 26050929; PMCID: PMC4618249.
    49. Sul JH, Raj T, de Jong S, de Bakker PI, Raychaudhuri S, Ophoff RA, Stranger BE, Eskin E, Han B. Accurate and fast multiple-testing correction in eQTL studies. Am J Hum Genet. 2015 Jun 04; 96(6):857-68. PMID: 26027500; PMCID: PMC4457958.
    50. Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. PLoS Genet. 2015 Apr; 11(4):e1005094. PMID: 25880434; PMCID: PMC4399881.
    51. Wang Z, Sul JH, Snir S, Lozano JA, Eskin E. Gene-Gene Interactions Detection Using a Two-stage Model. J Comput Biol. 2015 Jun; 22(6):563-76. PMID: 25871811; PMCID: PMC4449719.
    52. Furlotte NA, Eskin E. Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model. Genetics. 2015 May; 200(1):59-68. PMID: 25724382; PMCID: PMC4423381.
    53. Yang WY, Hormozdiari F, Eskin E, Pasaniuc B. A spatial haplotype copying model with applications to genotype imputation. J Comput Biol. 2015 May; 22(5):451-62. PMID: 25526526; PMCID: PMC4425418.
    54. Hormozdiari F, Eskin E. Memory efficient assembly of human genome. J Bioinform Comput Biol. 2015 Apr; 13(2):1550008. PMID: 25603998.
      View in: PubMed
    55. He D, Eskin E. IPED2X: a robust pedigree reconstruction algorithm for complicated pedigrees. J Bioinform Comput Biol. 2014 Dec; 12(6):1442007. PMID: 25553812.
      View in: PubMed
    56. Yang WY, Platt A, Chiang CW, Eskin E, Novembre J, Pasaniuc B. Spatial localization of recent ancestors for admixed individuals. G3 (Bethesda). 2014 Nov 03; 4(12):2505-18. PMID: 25371484; PMCID: PMC4267945.
    57. Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P, Pasaniuc B. Integrating functional data to prioritize causal variants in statistical fine-mapping studies. PLoS Genet. 2014 Oct; 10(10):e1004722. PMID: 25357204; PMCID: PMC4214605.
    58. Hormozdiari F, Kostem E, Kang EY, Pasaniuc B, Eskin E. Identifying causal variants at loci with multiple signals of association. Genetics. 2014 Oct; 198(2):497-508. PMID: 25104515; PMCID: PMC4196608.
    59. Hormozdiari F, Joo JW, Wadia A, Guan F, Ostrosky R, Sahai A, Eskin E. Privacy preserving protocol for detecting genetic relatives using rare variants. Bioinformatics. 2014 Jun 15; 30(12):i204-11. PMID: 24931985; PMCID: PMC4058916.
    60. Mangul S, Wu NC, Mancuso N, Zelikovsky A, Sun R, Eskin E. Accurate viral population assembly from ultra-deep sequencing data. Bioinformatics. 2014 Jun 15; 30(12):i329-37. PMID: 24932001; PMCID: PMC4058922.
    61. Hasin-Brumshtein Y, Hormozdiari F, Martin L, van Nas A, Eskin E, Lusis AJ, Drake TA. Allele-specific expression and eQTL analysis in mouse adipose tissue. BMC Genomics. 2014 Jun 13; 15:471. PMID: 24927774; PMCID: PMC4089026.
    62. Joo JW, Sul JH, Han B, Ye C, Eskin E. Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies. Genome Biol. 2014 Apr 07; 15(4):r61. PMID: 24708878; PMCID: PMC4053820.
    63. He D, Furlotte NA, Hormozdiari F, Joo JW, Wadia A, Ostrovsky R, Sahai A, Eskin E. Identifying genetic relatives without compromising privacy. Genome Res. 2014 Apr; 24(4):664-72. PMID: 24614977; PMCID: PMC3975065.
    64. Ohmen J, Kang EY, Li X, Joo JW, Hormozdiari F, Zheng QY, Davis RC, Lusis AJ, Eskin E, Friedman RA. Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis. J Assoc Res Otolaryngol. 2014 Jun; 15(3):335-52. PMID: 24570207; PMCID: PMC4010595.
    65. Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22; 63(15):1542-55. PMID: 24509276; PMCID: PMC3992204.
    66. Marsden CD, Lee Y, Kreppel K, Weakley A, Cornel A, Ferguson HM, Eskin E, Lanzaro GC. Diversity, differentiation, and linkage disequilibrium: prospects for association mapping in the malaria vector Anopheles arabiensis. G3 (Bethesda). 2014 Jan 10; 4(1):121-31. PMID: 24281424; PMCID: PMC3887528.
    67. Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. PLoS Genet. 2014 Jan; 10(1):e1004022. PMID: 24415945; PMCID: PMC3886926.
    68. Han B, Kang EY, Raychaudhuri S, de Bakker PI, Eskin E. Fast pairwise IBD association testing in genome-wide association studies. Bioinformatics. 2014 Jan 15; 30(2):206-13. PMID: 24158599; PMCID: PMC3892684.
    69. Eskin I, Hormozdiari F, Conde L, Riby J, Skibola CF, Eskin E, Halperin E. eALPS: estimating abundance levels in pooled sequencing using available genotyping data. J Comput Biol. 2013 Nov; 20(11):861-77. PMID: 24144111; PMCID: PMC4013753.
    70. He D, Wang Z, Han B, Parida L, Eskin E. IPED: inheritance path-based pedigree reconstruction algorithm using genotype data. J Comput Biol. 2013 Oct; 20(10):780-91. PMID: 24093229; PMCID: PMC3791035.
    71. Kostem E, Eskin E. Efficiently identifying significant associations in genome-wide association studies. J Comput Biol. 2013 Oct; 20(10):817-30. PMID: 24033261; PMCID: PMC3791046.
    72. Lagarrigue S, Martin L, Hormozdiari F, Roux PF, Pan C, van Nas A, Demeure O, Cantor R, Ghazalpour A, Eskin E, Lusis AJ. Analysis of allele-specific expression in mouse liver by RNA-Seq: a comparison with Cis-eQTL identified using genetic linkage. Genetics. 2013 Nov; 195(3):1157-66. PMID: 24026101; PMCID: PMC3813844.
    73. Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, Eskin E, You M, Kaminski N, Prows DR, Knoell DL, Fabisiak JP. Functional genomic assessment of phosgene-induced acute lung injury in mice. Am J Respir Cell Mol Biol. 2013 Sep; 49(3):368-83. PMID: 23590305; PMCID: PMC3824050.
    74. Yang WY, Hormozdiari F, Wang Z, He D, Pasaniuc B, Eskin E. Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data. Bioinformatics. 2013 Sep 15; 29(18):2245-52. PMID: 23825370; PMCID: PMC3753566.
    75. Sul JH, Han B, Ye C, Choi T, Eskin E. Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches. PLoS Genet. 2013 Jun; 9(6):e1003491. PMID: 23785294; PMCID: PMC3681686.
    76. Navon O, Sul JH, Han B, Conde L, Bracci PM, Riby J, Skibola CF, Eskin E, Halperin E. Rare variant association testing under low-coverage sequencing. Genetics. 2013 Jul; 194(3):769-79. PMID: 23636738; PMCID: PMC3697979.
    77. Kostem E, Eskin E. Improving the accuracy and efficiency of partitioning heritability into the contributions of genomic regions. Am J Hum Genet. 2013 Apr 04; 92(4):558-64. PMID: 23561845; PMCID: PMC3617385.
    78. Sul JH, Eskin E. Mixed models can correct for population structure for genomic regions under selection. Nat Rev Genet. 2013 Apr; 14(4):300. PMID: 23438871.
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    79. Wang Z, Hormozdiari F, Yang WY, Halperin E, Eskin E. CNVeM: copy number variation detection using uncertainty of read mapping. J Comput Biol. 2013 Mar; 20(3):224-36. PMID: 23421794; PMCID: PMC3590897.
    80. Davis RC, van Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. Genome-wide association mapping of blood cell traits in mice. Mamm Genome. 2013 Apr; 24(3-4):105-18. PMID: 23417284; PMCID: PMC3933005.
    81. Lagarrigue S, Hormozdiari F, Martin LJ, Lecerf F, Hasin Y, Rau C, Hagopian R, Xiao Y, Yan J, Drake TA, Ghazalpour A, Eskin E, Lusis AJ. Limited RNA editing in exons of mouse liver and adipose. Genetics. 2013 Apr; 193(4):1107-15. PMID: 23410828; PMCID: PMC3606090.
    82. He D, Han B, Eskin E. Hap-seq: an optimal algorithm for haplotype phasing with imputation using sequencing data. J Comput Biol. 2013 Feb; 20(2):80-92. PMID: 23383995; PMCID: PMC3576919.
    83. Parrish N, Sudakov B, Eskin E. Genome reassembly with high-throughput sequencing data. BMC Genomics. 2013; 14 Suppl 1:S8. PMID: 23368744; PMCID: PMC3549812.
    84. Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, Mehrabian M, Ursell LK, He A, Castellani LW, Zinker B, Kirby M, Drake TA, Drevon CA, Knight R, Gargalovic P, Kirchgessner T, Eskin E, Lusis AJ. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab. 2013 Jan 08; 17(1):141-52. PMID: 23312289; PMCID: PMC3545283.
    85. Calabrese G, Bennett BJ, Orozco L, Kang HM, Eskin E, Dombret C, De Backer O, Lusis AJ, Farber CR. Systems genetic analysis of osteoblast-lineage cells. PLoS Genet. 2012; 8(12):e1003150. PMID: 23300464; PMCID: PMC3531492.
    86. He D, Eskin E. Hap-seqX: expedite algorithm for haplotype phasing with imputation using sequence data. Gene. 2013 Apr 10; 518(1):2-6. PMID: 23269365.
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    87. Miller MB, Basu S, Cunningham J, Eskin E, Malone SM, Oetting WS, Schork N, Sul JH, Iacono WG, McGue M. The Minnesota Center for Twin and Family Research genome-wide association study. Twin Res Hum Genet. 2012 Dec; 15(6):767-74. PMID: 23363460; PMCID: PMC3561927.
    88. Flint J, Eskin E. Genome-wide association studies in mice. Nat Rev Genet. 2012 Nov; 13(11):807-17. PMID: 23044826.
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    89. Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012 Oct; 23(9-10):680-92. PMID: 22892838; PMCID: PMC3586763.
    90. Weiss JN, Karma A, MacLellan WR, Deng M, Rau CD, Rees CM, Wang J, Wisniewski N, Eskin E, Horvath S, Qu Z, Wang Y, Lusis AJ. "Good enough solutions" and the genetics of complex diseases. Circ Res. 2012 Aug 03; 111(4):493-504. PMID: 22859671; PMCID: PMC3428228.
    91. Hersch M, Peter B, Kang HM, Schüpfer F, Abriel H, Pedrazzini T, Eskin E, Beckmann JS, Bergmann S, Maurer F. Mapping genetic variants associated with beta-adrenergic responses in inbred mice. PLoS One. 2012; 7(7):e41032. PMID: 22859963; PMCID: PMC3409184.
    92. Bennett BJ, Orozco L, Kostem E, Erbilgin A, Dallinga M, Neuhaus I, Guan B, Wang X, Eskin E, Lusis AJ. High-resolution association mapping of atherosclerosis loci in mice. Arterioscler Thromb Vasc Biol. 2012 Aug; 32(8):1790-8. PMID: 22723443; PMCID: PMC3519423.
    93. Darnell G, Duong D, Han B, Eskin E. Incorporating prior information into association studies. Bioinformatics. 2012 Jun 15; 28(12):i147-53. PMID: 22689754; PMCID: PMC3371867.
    94. Friese RS, Ye C, Nievergelt CM, Schork AJ, Mahapatra NR, Rao F, Napolitan PS, Waalen J, Ehret GB, Munroe PB, Schmid-Schönbein GW, Eskin E, O'Connor DT. Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome. Circ Cardiovasc Genet. 2012 Aug 01; 5(4):430-40. PMID: 22670052; PMCID: PMC3467001.
    95. Listgarten J, Lippert C, Kadie CM, Davidson RI, Eskin E, Heckerman D. Improved linear mixed models for genome-wide association studies. Nat Methods. 2012 May 30; 9(6):525-6. PMID: 22669648; PMCID: PMC3597090.
    96. Yang WY, Novembre J, Eskin E, Halperin E. A model-based approach for analysis of spatial structure in genetic data. Nat Genet. 2012 May 20; 44(6):725-31. PMID: 22610118; PMCID: PMC3592563.
    97. Furlotte NA, Eskin E, Eyheramendy S. Genome-wide association mapping with longitudinal data. Genet Epidemiol. 2012 Jul; 36(5):463-71. PMID: 22581622; PMCID: PMC3625633.
    98. Furlotte NA, Kang EY, Van Nas A, Farber CR, Lusis AJ, Eskin E. Increasing association mapping power and resolution in mouse genetic studies through the use of meta-analysis for structured populations. Genetics. 2012 Jul; 191(3):959-67. PMID: 22505625; PMCID: PMC3389987.
    99. Han B, Eskin E. Interpreting meta-analyses of genome-wide association studies. PLoS Genet. 2012; 8(3):e1002555. PMID: 22396665; PMCID: PMC3291559.
    100. Sul JH, Han B, Eskin E. Increasing power of groupwise association test with likelihood ratio test. J Comput Biol. 2011 Nov; 18(11):1611-24. PMID: 21919745; PMCID: PMC3216097.
    101. Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, Goodson M, Furlotte NA, Eskin E, Nellåker C, Whitley H, Cleak J, Janowitz D, Hernandez-Pliego P, Edwards A, Belgard TG, Oliver PL, McIntyre RE, Bhomra A, Nicod J, Gan X, Yuan W, van der Weyden L, Steward CA, Bala S, Stalker J, Mott R, Durbin R, Jackson IJ, Czechanski A, Guerra-Assunção JA, Donahue LR, Reinholdt LG, Payseur BA, Ponting CP, Birney E, Flint J, Adams DJ. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature. 2011 Sep 14; 477(7364):289-94. PMID: 21921910.
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    102. Parrish N, Hormozdiari F, Eskin E. Assembly of non-unique insertion content using next-generation sequencing. BMC Bioinformatics. 2011; 12 Suppl 6:S3. PMID: 21989261; PMCID: PMC3194191.
    103. He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. Genotyping common and rare variation using overlapping pool sequencing. BMC Bioinformatics. 2011; 12 Suppl 6:S2. PMID: 21989232; PMCID: PMC3194190.
    104. Furlotte NA, Kang HM, Ye C, Eskin E. Mixed-model coexpression: calculating gene coexpression while accounting for expression heterogeneity. Bioinformatics. 2011 Jul 01; 27(13):i288-94. PMID: 21685083; PMCID: PMC3117390.
    105. Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet. 2011 Jun; 7(6):e1001393. PMID: 21695224; PMCID: PMC3111477.
    106. Han B, Eskin E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am J Hum Genet. 2011 May 13; 88(5):586-98. PMID: 21565292; PMCID: PMC3146723.
    107. Van Tyne D, Park DJ, Schaffner SF, Neafsey DE, Angelino E, Cortese JF, Barnes KG, Rosen DM, Lukens AK, Daniels RF, Milner DA, Johnson CA, Shlyakhter I, Grossman SR, Becker JS, Yamins D, Karlsson EK, Ndiaye D, Sarr O, Mboup S, Happi C, Furlotte NA, Eskin E, Kang HM, Hartl DL, Birren BW, Wiegand RC, Lander ES, Wirth DF, Volkman SK, Sabeti PC. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011 Apr; 7(4):e1001383. PMID: 21533027; PMCID: PMC3080868.
    108. He D, Hormozdiari F, Furlotte N, Eskin E. Efficient algorithms for tandem copy number variation reconstruction in repeat-rich regions. Bioinformatics. 2011 Jun 01; 27(11):1513-20. PMID: 21505028; PMCID: PMC3102223.
    109. Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet. 2011 Apr; 7(4):e1002038. PMID: 21490954; PMCID: PMC3072371.
    110. Kostem E, Lozano JA, Eskin E. Increasing power of genome-wide association studies by collecting additional single-nucleotide polymorphisms. Genetics. 2011 Jun; 188(2):449-60. PMID: 21467568; PMCID: PMC3122306.
    111. Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol. 2011 Mar 16; 5:43. PMID: 21410935; PMCID: PMC3070648.
    112. Sul JH, Han B, He D, Eskin E. An optimal weighted aggregated association test for identification of rare variants involved in common diseases. Genetics. 2011 May; 188(1):181-8. PMID: 21368279; PMCID: PMC3120154.
    113. Han B, Hackel BM, Eskin E. Postassociation cleaning using linkage disequilibrium information. Genet Epidemiol. 2011 Jan; 35(1):1-10. PMID: 21181893.
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    114. He D, Furlotte N, Eskin E. Detection and reconstruction of tandemly organized de novo copy number variations. BMC Bioinformatics. 2010 Dec 14; 11 Suppl 11:S12. PMID: 21172047; PMCID: PMC3024866.
    115. Kenny EE, Kim M, Gusev A, Lowe JK, Salit J, Smith JG, Kovvali S, Kang HM, Newton-Cheh C, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Eskin E, Breslow JL, Pe'er I. Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population. Hum Mol Genet. 2011 Feb 15; 20(4):827-39. PMID: 21118897; PMCID: PMC3024042.
    116. McLachlan S, Lee SM, Steele TM, Hawthorne PL, Zapala MA, Eskin E, Schork NJ, Anderson GJ, Vulpe CD. In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiol Genomics. 2011 Feb 11; 43(3):136-47. PMID: 21062905; PMCID: PMC3055709.
    117. Zaitlen N, Eskin E. Imputation aware meta-analysis of genome-wide association studies. Genet Epidemiol. 2010 Sep; 34(6):537-42. PMID: 20717975; PMCID: PMC3102182.
    118. Santana R, Mendiburu A, Zaitlen N, Eskin E, Lozano JA. Multi-marker tagging single nucleotide polymorphism selection using estimation of distribution algorithms. Artif Intell Med. 2010 Nov; 50(3):193-201. PMID: 20650616.
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    119. He D, Choi A, Pipatsrisawat K, Darwiche A, Eskin E. Optimal algorithms for haplotype assembly from whole-genome sequence data. Bioinformatics. 2010 Jun 15; 26(12):i183-90. PMID: 20529904; PMCID: PMC2881399.
    120. Zhang K, Weder AB, Eskin E, O'Connor DT. Genome-wide case/control studies in hypertension: only the 'tip of the iceberg'. J Hypertens. 2010 Jun; 28(6):1115-23. PMID: 20216088; PMCID: PMC2873167.
    121. Kirby A, Kang HM, Wade CM, Cotsapas C, Kostem E, Han B, Furlotte N, Kang EY, Rivas M, Bogue MA, Frazer KA, Johnson FM, Beilharz EJ, Cox DR, Eskin E, Daly MJ. Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics. 2010 Jul; 185(3):1081-95. PMID: 20439770; PMCID: PMC2907194.
    122. Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nat Genet. 2010 Apr; 42(4):348-54. PMID: 20208533; PMCID: PMC3092069.
    123. Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ, Leow AD, Toga AW, Sul JH, Kang HM, Eskin E, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, Webster J, DeChairo BM, Potkin SG, Jack CR, Weiner MW, Thompson PM. Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease. Neuroimage. 2010 Jun; 51(2):542-54. PMID: 20197096; PMCID: PMC2856746.
    124. Kang HM, Zaitlen NA, Eskin E. EMINIM: an adaptive and memory-efficient algorithm for genotype imputation. J Comput Biol. 2010 Mar; 17(3):547-60. PMID: 20377463; PMCID: PMC3198882.
    125. Kang EY, Ye C, Shpitser I, Eskin E. Detecting the presence and absence of causal relationships between expression of yeast genes with very few samples. J Comput Biol. 2010 Mar; 17(3):533-46. PMID: 20377462; PMCID: PMC3198891.
    126. Bennett BJ, Farber CR, Orozco L, Kang HM, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, Truong A, Yang WP, He A, Kayne P, Gargalovic P, Kirchgessner T, Pan C, Castellani LW, Kostem E, Furlotte N, Drake TA, Eskin E, Lusis AJ. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res. 2010 Feb; 20(2):281-90. PMID: 20054062; PMCID: PMC2813484.
    127. Yang IV, Wade CM, Kang HM, Alper S, Rutledge H, Lackford B, Eskin E, Daly MJ, Schwartz DA. Identification of novel genes that mediate innate immunity using inbred mice. Genetics. 2009 Dec; 183(4):1535-44. PMID: 19805818; PMCID: PMC2787437.
    128. Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, Schork NJ, O'Connor DT, Taylor P. Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs. J Pharmacol Exp Ther. 2009 Nov; 331(2):419-28. PMID: 19671882; PMCID: PMC2775266.
    129. Han B, Kang HM, Eskin E. Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet. 2009 Apr; 5(4):e1000456. PMID: 19381255; PMCID: PMC2663787.
    130. Zaitlen N, Kang HM, Eskin E. Linkage effects and analysis of finite sample errors in the HapMap. Hum Hered. 2009; 68(2):73-86. PMID: 19365134; PMCID: PMC2874737.
    131. Ye C, Galbraith SJ, Liao JC, Eskin E. Using network component analysis to dissect regulatory networks mediated by transcription factors in yeast. PLoS Comput Biol. 2009 Mar; 5(3):e1000311. PMID: 19300475; PMCID: PMC2649002.
    132. Kang HM, Ye C, Eskin E. Accurate discovery of expression quantitative trait loci under confounding from spurious and genuine regulatory hotspots. Genetics. 2008 Dec; 180(4):1909-25. PMID: 18791227; PMCID: PMC2600931.
    133. Ghazalpour A, Doss S, Kang H, Farber C, Wen PZ, Brozell A, Castellanos R, Eskin E, Smith DJ, Drake TA, Lusis AJ. High-resolution mapping of gene expression using association in an outbred mouse stock. PLoS Genet. 2008 Aug 08; 4(8):e1000149. PMID: 18688273; PMCID: PMC2483929.
    134. Eskin E. Increasing power in association studies by using linkage disequilibrium structure and molecular function as prior information. Genome Res. 2008 Apr; 18(4):653-60. PMID: 18353808; PMCID: PMC2279252.
    135. Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E. Efficient control of population structure in model organism association mapping. Genetics. 2008 Mar; 178(3):1709-23. PMID: 18385116; PMCID: PMC2278096.
    136. Olshen AB, Gold B, Lohmueller KE, Struewing JP, Satagopan J, Stefanov SA, Eskin E, Kirchhoff T, Lautenberger JA, Klein RJ, Friedman E, Norton L, Ellis NA, Viale A, Lee CS, Borgen PI, Clark AG, Offit K, Boyd J. Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping. BMC Genet. 2008 Feb 05; 9:14. PMID: 18251999; PMCID: PMC2259380.
    137. Barrett TB, Emberton JE, Nievergelt CM, Liang SG, Hauger RL, Eskin E, Schork NJ, Kelsoe JR. Further evidence for association of GRK3 to bipolar disorder suggests a second disease mutation. Psychiatr Genet. 2007 Dec; 17(6):315-22. PMID: 18075471.
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    138. Frazer KA, Eskin E, Kang HM, Bogue MA, Hinds DA, Beilharz EJ, Gupta RV, Montgomery J, Morenzoni MM, Nilsen GB, Pethiyagoda CL, Stuve LL, Johnson FM, Daly MJ, Wade CM, Cox DR. A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature. 2007 Aug 30; 448(7157):1050-3. PMID: 17660834.
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    139. Eskin E, Snir S. Incorporating homologues into sequence embeddings for protein analysis. J Bioinform Comput Biol. 2007 Jun; 5(3):717-38. PMID: 17688313.
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    140. Rao F, Wen G, Gayen JR, Das M, Vaingankar SM, Rana BK, Mahata M, Kennedy BP, Salem RM, Stridsberg M, Abel K, Smith DW, Eskin E, Schork NJ, Hamilton BA, Ziegler MG, Mahata SK, O'Connor DT. Catecholamine release-inhibitory peptide catestatin (chromogranin A(352-372)): naturally occurring amino acid variant Gly364Ser causes profound changes in human autonomic activity and alters risk for hypertension. Circulation. 2007 May 01; 115(17):2271-81. PMID: 17438154.
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    141. Zaitlen N, Kang HM, Eskin E, Halperin E. Leveraging the HapMap correlation structure in association studies. Am J Hum Genet. 2007 Apr; 80(4):683-91. PMID: 17357074; PMCID: PMC1852710.
    142. Ye C, Eskin E. Discovering tightly regulated and differentially expressed gene sets in whole genome expression data. Bioinformatics. 2007 Jan 15; 23(2):e84-90. PMID: 17237110.
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    143. Eskin E, Sharan R, Halperin E. A note on phasing long genomic regions using local haplotype predictions. J Bioinform Comput Biol. 2006 Jun; 4(3):639-47. PMID: 16960967.
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    144. O'Rourke S, Chechik G, Friedman R, Eskin E. Discrete profile comparison using information bottleneck. BMC Bioinformatics. 2006 Mar 20; 7 Suppl 1:S8. PMID: 16723011; PMCID: PMC1810319.
    145. Marchini J, Cutler D, Patterson N, Stephens M, Eskin E, Halperin E, Lin S, Qin ZS, Munro HM, Abecasis GR, Donnelly P. A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet. 2006 Mar; 78(3):437-50. PMID: 16465620; PMCID: PMC1380287.
    146. Riddle EL, Rana BK, Murthy KK, Rao F, Eskin E, O'Connor DT, Insel PA. Polymorphisms and haplotypes of the regulator of G protein signaling-2 gene in normotensives and hypertensives. Hypertension. 2006 Mar; 47(3):415-20. PMID: 16432041.
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    147. Zaitlen NA, Kang HM, Feolo ML, Sherry ST, Halperin E, Eskin E. Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP. Genome Res. 2005 Nov; 15(11):1594-600. PMID: 16251470; PMCID: PMC1310648.
    148. Zhang S, Haas B, Eskin E, Bafna V. Searching genomes for noncoding RNA using FastR. IEEE/ACM Trans Comput Biol Bioinform. 2005 Oct-Dec; 2(4):366-79. PMID: 17044173.
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    149. Hinds DA, Stuve LL, Nilsen GB, Halperin E, Eskin E, Ballinger DG, Frazer KA, Cox DR. Whole-genome patterns of common DNA variation in three human populations. Science. 2005 Feb 18; 307(5712):1072-9. PMID: 15718463.
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    150. Tompa M, Li N, Bailey TL, Church GM, De Moor B, Eskin E, Favorov AV, Frith MC, Fu Y, Kent WJ, Makeev VJ, Mironov AA, Noble WS, Pavesi G, Pesole G, Régnier M, Simonis N, Sinha S, Thijs G, van Helden J, Vandenbogaert M, Weng Z, Workman C, Ye C, Zhu Z. Assessing computational tools for the discovery of transcription factor binding sites. Nat Biotechnol. 2005 Jan; 23(1):137-44. PMID: 15637633.
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    151. Price AL, Eskin E, Pevzner PA. Whole-genome analysis of Alu repeat elements reveals complex evolutionary history. Genome Res. 2004 Nov; 14(11):2245-52. PMID: 15520288; PMCID: PMC525682.
    152. Halperin E, Eskin E. Haplotype reconstruction from genotype data using Imperfect Phylogeny. Bioinformatics. 2004 Aug 12; 20(12):1842-9. PMID: 14988101.
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    153. Leslie CS, Eskin E, Cohen A, Weston J, Noble WS. Mismatch string kernels for discriminative protein classification. Bioinformatics. 2004 Mar 01; 20(4):467-76. PMID: 14990442.
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    154. Eskin E, Halperin E, Karp RM. Efficient reconstruction of haplotype structure via perfect phylogeny. J Bioinform Comput Biol. 2003 Apr; 1(1):1-20. PMID: 15290779.
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    155. Eskin E, Keich U, Gelfand MS, Pevzner PA. Genome-wide analysis of bacterial promoter regions. Pac Symp Biocomput. 2003; 29-40. PMID: 12603015.
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    156. Eskin E, Noble WS, Singer Y. Protein family classification using sparse markov transducers. J Comput Biol. 2003; 10(2):187-213. PMID: 12804091.
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    157. Leslie C, Eskin E, Noble WS. The spectrum kernel: a string kernel for SVM protein classification. Pac Symp Biocomput. 2002; 564-75. PMID: 11928508.
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    158. Eskin E, Pevzner PA. Finding composite regulatory patterns in DNA sequences. Bioinformatics. 2002; 18 Suppl 1:S354-63. PMID: 12169566.
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    159. Eskin E, Noble WS, Singer Y. Using substitution matrices to estimate probability distributions for biological sequences. J Comput Biol. 2002; 9(6):775-91. PMID: 12614546.
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