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Monbouquette Harold

TitleProfessor
InstitutionUniversity of California Los Angeles
DepartmentChemical and Biomolecular Engineering
AddressDepartment of Chemical Engineering
Box 951592
Los Angeles CA 90095
Phone(310) 206-4107
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    Collapse Research 
    Collapse Research Activities and Funding
    Multifunctional Microprobe for Multiple Neurotransmitter Sensing and Optogenetics
    NIH/NINDS R01NS087494Apr 1, 2014 - Mar 31, 2019
    Role: Principal Investigator
    PCR-independent Reagent-Free Nucleic Acid Detection
    NIH/NHGRI R21HG006157May 20, 2011 - Apr 30, 2014
    Role: Principal Investigator
    A Micromachined, Multielectrode Microprobe for Monitoring Glutamate and Dopamine
    NIH/NINDS R21NS064547Jul 16, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Unique Isoprenoid Biosynthesis Machinery of the Hyperthermophilic Archaea
    NIH/NIGMS R01GM077627Mar 4, 2006 - Feb 28, 2010
    Role: Principal Investigator
    Biotechnology Training in Biomedical Sciences and Engineering
    NIH/NIGMS T32GM067555Apr 1, 2003 - Jun 30, 2020
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wang B, Koo B, Huang LW, Monbouquette HG. Microbiosensor fabrication by polydimethylsiloxane stamping for combined sensing of glucose and choline. Analyst. 2018 Sep 18. PMID: 30226501.
      View in: PubMed
    2. Koo B, Yorita AM, Schmidt JJ, Monbouquette HG. Amplification-free, sequence-specific 16S rRNA detection at 1 aM. Lab Chip. 2018 Jul 10. PMID: 29987290.
      View in: PubMed
    3. Clay M, Monbouquette HG. A Detailed Model of Electroenzymatic Glutamate Biosensors To Aid in Sensor Optimization and in Applications in Vivo. ACS Chem Neurosci. 2018 02 21; 9(2):241-251. PMID: 29076724.
      View in: PubMed
    4. Wang B, Koo B, Monbouquette HG. Enzyme Deposition by Polydimethylsiloxane Stamping for Biosensor Fabrication. Electroanalysis. 2017 Oct; 29(10):2300-2306. PMID: 29628750.
      View in: PubMed
    5. Esfandiari L, Wang S, Wang S, Banda A, Lorenzini M, Kocharyan G, Monbouquette HG, Schmidt JJ. PCR-Independent Detection of Bacterial Species-Specific 16S rRNA at 10 fM by a Pore-Blockage Sensor. Biosensors (Basel). 2016 Jul 22; 6(3). PMID: 27455337.
      View in: PubMed
    6. Malvaez M, Greenfield VY, Wang AS, Yorita AM, Feng L, Linker KE, Monbouquette HG, Wassum KM. Corrigendum: Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions. Sci Rep. 2016 Feb 15; 6:20891. PMID: 26876785; PMCID: PMC4753403.
    7. Malvaez M, Greenfield VY, Wang AS, Yorita AM, Feng L, Linker KE, Monbouquette HG, Wassum KM. Basolateral amygdala rapid glutamate release encodes an outcome-specific representation vital for reward-predictive cues to selectively invigorate reward-seeking actions. Sci Rep. 2015 Jul 27; 5:12511. PMID: 26212790; PMCID: PMC4648450.
    8. Esfandiari L, Lorenzini M, Kocharyan G, Monbouquette HG, Schmidt JJ. Sequence-specific DNA detection at 10 fM by electromechanical signal transduction. Anal Chem. 2014 Oct 07; 86(19):9638-43. PMID: 25203740; PMCID: PMC4188267.
    9. Lo MK, Gard MN, Goldsmith BR, Garcia-Garibay MA, Monbouquette HG. Synthesis and micropatterning of photocatalytically reactive self-assembled monolayers covalently linked to Si(100) surfaces via a Si-C bond. Langmuir. 2012 Nov 20; 28(46):16156-66. PMID: 23083520.
      View in: PubMed
    10. Tolosa VM, Wassum KM, Maidment NT, Monbouquette HG. Electrochemically deposited iridium oxide reference electrode integrated with an electroenzymatic glutamate sensor on a multi-electrode array microprobe. Biosens Bioelectron. 2013 Apr 15; 42:256-60. PMID: 23208095.
      View in: PubMed
    11. Esfandiari L, Monbouquette HG, Schmidt JJ. Sequence-specific nucleic acid detection from binary pore conductance measurement. J Am Chem Soc. 2012 Sep 26; 134(38):15880-6. PMID: 22931376; PMCID: PMC3480342.
    12. Tseng TT, Monbouquette HG. Implantable Microprobe with Arrayed Microsensors for Combined Amperometric Monitoring of the Neurotransmitters, Glutamate and Dopamine. J Electroanal Chem (Lausanne). 2012 Aug 15; 682:141-146. PMID: 23139647.
      View in: PubMed
    13. Wassum KM, Tolosa VM, Tseng TC, Balleine BW, Monbouquette HG, Maidment NT. Transient extracellular glutamate events in the basolateral amygdala track reward-seeking actions. J Neurosci. 2012 Feb 22; 32(8):2734-46. PMID: 22357857; PMCID: PMC3548241.
    14. Chiu ML, Ytterberg AJ, Ogorzalek Loo RR, Loo JA, Monbouquette HG. Characterization of morphine-glucose-6-phosphate dehydrogenase conjugates by mass spectrometry. Bioconjug Chem. 2011 Aug 17; 22(8):1595-604. PMID: 21678975; PMCID: PMC3157545.
    15. Radhakrishnan C, Lo MK, Knobler CM, Garcia-Garibay MA, Monbouquette HG. Capping-ligand effect on the stability of CdSe quantum dot Langmuir monolayers. Langmuir. 2011 Mar 15; 27(6):2099-103. PMID: 21329375.
      View in: PubMed
    16. Chiu ML, Tseng TT, Monbouquette HG. A convenient homogeneous enzyme immunoassay for estradiol detection. Biotechnol Appl Biochem. 2011 Jan-Feb; 58(1):75-82. PMID: 21446962.
      View in: PubMed
    17. Chiu ML, Lai D, Monbouquette HG. An influenza hemagglutinin A peptide assay based on the enzyme-multiplied immunoassay technique. J Immunoassay Immunochem. 2011; 32(1):1-17. PMID: 21253966.
      View in: PubMed
    18. Galatsis K, Wang KL, Ozkan M, Ozkan CS, Huang Y, Chang JP, Monbouquette HG, Chen Y, Nealey P, Botros Y. Patterning and templating for nanoelectronics. Adv Mater. 2010 Feb 09; 22(6):769-78. PMID: 20217787.
      View in: PubMed
    19. Goldsmith LE, Pupols M, Kickhoefer VA, Rome LH, Monbouquette HG. Utilization of a protein "shuttle" to load vault nanocapsules with gold probes and proteins. ACS Nano. 2009 Oct 27; 3(10):3175-83. PMID: 19775119.
      View in: PubMed
    20. Lai D, Lluncor B, Schröder I, Gunsalus RP, Liao JC, Monbouquette HG. Reconstruction of the archaeal isoprenoid ether lipid biosynthesis pathway in Escherichia coli through digeranylgeranylglyceryl phosphate. Metab Eng. 2009 May; 11(3):184-91. PMID: 19558961; PMCID: PMC2726270.
    21. Lim S, Springstead JR, Yu M, Bartkowski W, Schröder I, Monbouquette HG. Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus. Extremophiles. 2009 Jan; 13(1):191-8. PMID: 19082689.
      View in: PubMed
    22. Ng BC, Yu M, Gopal A, Rome LH, Monbouquette HG, Tolbert SH. Encapsulation of semiconducting polymers in vault protein cages. Nano Lett. 2008 Oct; 8(10):3503-9. PMID: 18803422; PMCID: PMC3046045.
    23. Yu M, Ng BC, Rome LH, Tolbert SH, Monbouquette HG. Reversible pH lability of cross-linked vault nanocapsules. Nano Lett. 2008 Oct; 8(10):3510-5. PMID: 18803423; PMCID: PMC3046048.
    24. Chen HY, Lo MK, Yang G, Monbouquette HG, Yang Y. Nanoparticle-assisted high photoconductive gain in composites of polymer and fullerene. Nat Nanotechnol. 2008 Sep; 3(9):543-7. PMID: 18772915; PMCID: PMC3966304.
    25. Wassum KM, Tolosa VM, Wang J, Walker E, Monbouquette HG, Maidment NT. Silicon Wafer-Based Platinum Microelectrode Array Biosensor for Near Real-Time Measurement of Glutamate in Vivo. Sensors (Basel). 2008; 8(8):5023-5036. PMID: 19543440.
      View in: PubMed
    26. Lai D, Springstead JR, Monbouquette HG. Effect of growth temperature on ether lipid biochemistry in Archaeoglobus fulgidus. Extremophiles. 2008 Mar; 12(2):271-8. PMID: 18157503.
      View in: PubMed
    27. Walker E, Wang J, Hamdi N, Monbouquette HG, Maidment NT. Selective detection of extracellular glutamate in brain tissue using microelectrode arrays coated with over-oxidized polypyrrole. Analyst. 2007 Nov; 132(11):1107-11. PMID: 17955144.
      View in: PubMed
    28. Goldsmith LE, Yu M, Rome LH, Monbouquette HG. Vault nanocapsule dissociation into halves triggered at low pH. Biochemistry. 2007 Mar 13; 46(10):2865-75. PMID: 17302392.
      View in: PubMed
    29. Radhakrishnan C, Lo MK, Warrier MV, Garcia-Garibay MA, Monbouquette HG. Photocatalytic reduction of an azide-terminated self-assembled monolayer using CdS quantum dots. Langmuir. 2006 May 23; 22(11):5018-24. PMID: 16700589.
      View in: PubMed
    30. Ko FH, Monbouquette HG. Photometric and electrochemical enzyme-multiplied assay techniques using beta-galactosidase as reporter enzyme. Biotechnol Prog. 2006 May-Jun; 22(3):860-5. PMID: 16739972.
      View in: PubMed
    31. Schröder I, Vadas A, Johnson E, Lim S, Monbouquette HG. A novel archaeal alanine dehydrogenase homologous to ornithine cyclodeaminase and mu-crystallin. J Bacteriol. 2004 Nov; 186(22):7680-9. PMID: 15516582; PMCID: PMC524889.
    32. Gallagher DT, Monbouquette HG, Schröder I, Robinson H, Holden MJ, Smith NN. Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin. J Mol Biol. 2004 Sep 03; 342(1):119-30. PMID: 15313611.
      View in: PubMed
    33. Lim S, Schröder I, Monbouquette HG. A thermostable shikimate 5-dehydrogenase from the archaeon Archaeoglobus fulgidus. FEMS Microbiol Lett. 2004 Sep 01; 238(1):101-6. PMID: 15336409.
      View in: PubMed
    34. Warrier M, Lo MK, Monbouquette H, Garcia-Garibay MA. Photocatalytic reduction of aromatic azides to amines using CdS and CdSe nanoparticles. Photochem Photobiol Sci. 2004 Sep; 3(9):859-63. PMID: 15346187.
      View in: PubMed
    35. Vadas AJ, Schröder I, Monbouquette HG. Room-temperature synthesis of L-alanine using the alanine dehydrogenase of the hyperthermophilic archaeon Archaeoglobus fulgidus. Biotechnol Prog. 2002 Jul-Aug; 18(4):909-11. PMID: 12153329.
      View in: PubMed
    36. Vadas A, Monbouquette HG, Johnson E, Schröder I. Identification and characterization of a novel ferric reductase from the hyperthermophilic Archaeon Archaeoglobus fulgidus. J Biol Chem. 1999 Dec 17; 274(51):36715-21. PMID: 10593977.
      View in: PubMed
    37. Korgel BA, van Zanten JH, Monbouquette HG. Vesicle size distributions measured by flow field-flow fractionation coupled with multiangle light scattering. Biophys J. 1998 Jun; 74(6):3264-72. PMID: 9635780; PMCID: PMC1299667.
    38. Kinnear KT, Monbouquette HG. An amperometric fructose biosensor based on fructose dehydrogenase immobilized in a membrane mimetic layer on gold. Anal Chem. 1997 May 01; 69(9):1771-5. PMID: 21639302.
      View in: PubMed
    39. Kinnear KT, Monbouquette HG. Electroenzymology in membrane-mimetic media. Ann N Y Acad Sci. 1994 Nov 30; 745:232-9. PMID: 7832512.
      View in: PubMed
    40. Pepper CB, Monbouquette HG. Issues in the culture of the extremely thermophilic methanogen, Methanothermus fervidus. Biotechnol Bioeng. 1993 Apr 25; 41(10):970-8. PMID: 18601279.
      View in: PubMed
    41. van Zanten JH, Monbouquette HG. Biomimetic metal-sorbing vesicles: Cd2+ uptake by phosphatidylcholine vesicles doped with ionophore A23187. Biotechnol Prog. 1992 Nov-Dec; 8(6):546-52. PMID: 1369037.
      View in: PubMed
    42. Monbouquette HG. Modeling high-biomass-density cell recycle fermentors. Biotechnol Bioeng. 1992 Mar 05; 39(5):498-503. PMID: 18600975.
      View in: PubMed
    43. Korgel BA, Rotem A, Monbouquette HG. Effective diffusivity of galactose in calcium alginate gels containing immobilized Zymomonas mobilis. Biotechnol Prog. 1992 Mar-Apr; 8(2):111-7. PMID: 1368005.
      View in: PubMed