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Sinsheimer Janet

Title(s)Professor, Biomathematics
Phone(310) 825-8685
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    Other Positions
    Title(s)Professor, Human Genetics


    Collapse Research 
    Collapse Research Activities and Funding
    Maternal/fetal genotype incompatibility in schizophrenia
    NIH/NIMH R21MH066001Aug 2, 2002 - Jul 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chuang YH, Paul KC, Sinsheimer JS, Bronstein JM, Bordelon YM, Ritz B. Genetic variants in nicotinic receptors and smoking cessation in Parkinson's disease. Parkinsonism Relat Disord. 2019 Feb 01. PMID: 30777653.
      View in: PubMed
    2. Lin LY, Chun Chang S, O'Hearn J, Hui ST, Seldin M, Gupta P, Bondar G, Deng M, Jauhiainen R, Kuusisto J, Laakso M, Sinsheimer JS, Deb A, Rau C, Ren S, Wang Y, Lusis AJ, Wang JJ, Huertas-Vazquez A. Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans. G3 (Bethesda). 2018 11 06; 8(11):3499-3506. PMID: 30201759.
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    3. Landeros A, Stutz T, Keys KL, Alekseyenko A, Sinsheimer JS, Lange K, Sehl ME. BioSimulator.jl: Stochastic simulation in Julia. Comput Methods Programs Biomed. 2018 Dec; 167:23-35. PMID: 30501857.
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    4. Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, Mohlke KL, Laakso M, Pajukanta P, Ko A. Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nat Commun. 2018 08 22; 9(1):3472. PMID: 30135520.
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    5. Lake JA, Larsen J, Tran DT, Sinsheimer JS. Uncovering the Genomic Origins of Life. Genome Biol Evol. 2018 07 01; 10(7):1705-1714. PMID: 29947758.
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    6. vonHoldt BM, Ji SS, Aardema ML, Stahler DR, Udell MAR, Sinsheimer JS. Activity of Genes with Functions in Human Williams-Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome. Genome Biol Evol. 2018 06 01; 10(6):1546-1553. PMID: 29860323.
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    7. Pan DZ, Garske KM, Alvarez M, Bhagat YV, Boocock J, Nikkola E, Miao Z, Raulerson CK, Cantor RM, Civelek M, Glastonbury CA, Small KS, Boehnke M, Lusis AJ, Sinsheimer JS, Mohlke KL, Laakso M, Pajukanta P, Ko A. Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS. Nat Commun. 2018 04 17; 9(1):1512. PMID: 29666371.
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    8. Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. NFE2L2, PPARGC1a, and pesticides and Parkinson's disease risk and progression. Mech Ageing Dev. 2018 07; 173:1-8. PMID: 29630901.
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    9. Gilbert PS, Wu J, Simon MW, Sinsheimer JS, Alfaro ME. Filtering nucleotide sites by phylogenetic signal to noise ratio increases confidence in the Neoaves phylogeny generated from ultraconserved elements. Mol Phylogenet Evol. 2018 09; 126:116-128. PMID: 29626666.
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    10. Palmer CGS, McConkie-Rosell A, Holm IA, LeBlanc K, Sinsheimer JS, Briere LC, Dorrani N, Herzog MR, Lincoln S, Schoch K, Spillmann RC, Brokamp E. Understanding Adult Participant and Parent Empowerment Prior to Evaluation in the Undiagnosed Diseases Network. J Genet Couns. 2018 Sep; 27(5):1087-1101. PMID: 29497923.
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    11. Boudreault P, Wolfson A, Berman B, Venne VL, Sinsheimer JS, Palmer C. Bilingual Cancer Genetic Education Modules for the Deaf Community: Development and Evaluation of the Online Video Material. J Genet Couns. 2018 Apr; 27(2):457-469. PMID: 29260487.
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    12. Kusters CDJ, Paul KC, Guella I, Bronstein JM, Sinsheimer JS, Farrer MJ, Ritz BR. Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson's disease. Parkinsonism Relat Disord. 2018 Feb; 47:39-44. PMID: 29191473.
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    13. vonHoldt BM, Shuldiner E, Koch IJ, Kartzinel RY, Hogan A, Brubaker L, Wanser S, Stahler D, Wynne CDL, Ostrander EA, Sinsheimer JS, Udell MAR. Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs. Sci Adv. 2017 Jul; 3(7):e1700398. PMID: 28776031.
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    14. Paul KC, Sinsheimer JS, Cockburn M, Bronstein JM, Bordelon Y, Ritz B. Organophosphate pesticides and PON1 L55M in Parkinson's disease progression. Environ Int. 2017 10; 107:75-81. PMID: 28689109.
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    15. Lorenzo Bermejo J, Boekstegers F, González Silos R, Marcelain K, Baez Benavides P, Barahona Ponce C, Müller B, Ferreccio C, Koshiol J, Fischer C, Peil B, Sinsheimer J, Fuentes Guajardo M, Barajas O, Gonzalez-Jose R, Bedoya G, Cátira Bortolini M, Canizales-Quinteros S, Gallo C, Ruiz Linares A, Rothhammer F. Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile. PLoS Genet. 2017 May; 13(5):e1006756. PMID: 28542165.
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    16. Crandall CJ, Manson JE, Hohensee C, Horvath S, Wactawski-Wende J, LeBlanc ES, Vitolins MZ, Nassir R, Sinsheimer JS. Association of genetic variation in the tachykinin receptor 3 locus with hot flashes and night sweats in the Women's Health Initiative Study. Menopause. 2017 03; 24(3):252-261. PMID: 28231077.
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    17. Clark MM, Chazara O, Sobel EM, Gjessing HK, Magnus P, Moffett A, Sinsheimer JS. Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes. Hum Hered. 2016; 81(4):181-193. PMID: 28214848.
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    18. Cybis GB, Sinsheimer JS, Bedford T, Rambaut A, Lemey P, Suchard MA. Bayesian nonparametric clustering in phylogenetics: modeling antigenic evolution in influenza. Stat Med. 2018 Jan 30; 37(2):195-206. PMID: 28098392.
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    19. Fejzo MS, Myhre R, Colodro-Conde L, MacGibbon KW, Sinsheimer JS, Reddy MVPL, Pajukanta P, Nyholt DR, Wright MJ, Martin NG, Engel SM, Medland SE, Magnus P, Mullin PM. Genetic analysis of hyperemesis gravidarum reveals association with intracellular calcium release channel (RYR2). Mol Cell Endocrinol. 2017 01 05; 439:308-316. PMID: 27663074.
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    20. Lee PC, Raaschou-Nielsen O, Lill CM, Bertram L, Sinsheimer JS, Hansen J, Ritz B. Gene-environment interactions linking air pollution and inflammation in Parkinson's disease. Environ Res. 2016 Nov; 151:713-720. PMID: 27640071.
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    21. Gatto NM, Paul KC, Sinsheimer JS, Bronstein JM, Bordelon Y, Rausch R, Ritz B. Vitamin D receptor gene polymorphisms and cognitive decline in Parkinson's disease. J Neurol Sci. 2016 Nov 15; 370:100-106. PMID: 27772736.
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    22. Palmer CG, Boudreault P, Berman BA, Wolfson A, Duarte L, Venne VL, Sinsheimer JS. Bilingual approach to online cancer genetics education for Deaf American Sign Language users produces greater knowledge and confidence than English text only: A randomized study. Disabil Health J. 2017 01; 10(1):23-32. PMID: 27594054.
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    23. Paul KC, Rausch R, Creek MM, Sinsheimer JS, Bronstein JM, Bordelon Y, Ritz B. APOE, MAPT, and COMT and Parkinson's Disease Susceptibility and Cognitive Symptom Progression. J Parkinsons Dis. 2016 04 02; 6(2):349-59. PMID: 27061069.
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    24. Lake JA, Larsen J, Sarna B, de la Haba RR, Pu Y, Koo H, Zhao J, Sinsheimer JS. Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria. Genome Biol Evol. 2016 Mar 10; 8(3):578. PMID: 26966240; PMCID: PMC4824009.
    25. Chuang YH, Lill CM, Lee PC, Hansen J, Lassen CF, Bertram L, Greene N, Sinsheimer JS, Ritz B. Gene-Environment Interaction in Parkinson's Disease: Coffee, ADORA2A, and CYP1A2. Neuroepidemiology. 2016; 47(3-4):192-200. PMID: 28135712.
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    26. Janowitz Koch I, Clark MM, Thompson MJ, Deere-Machemer KA, Wang J, Duarte L, Gnanadesikan GE, McCoy EL, Rubbi L, Stahler DR, Pellegrini M, Ostrander EA, Wayne RK, Sinsheimer JS, vonHoldt BM. The concerted impact of domestication and transposon insertions on methylation patterns between dogs and grey wolves. Mol Ecol. 2016 Apr; 25(8):1838-55. PMID: 27112634.
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    27. Lake JA, Larsen J, Sarna B, de la Haba RR, Pu Y, Koo H, Zhao J, Sinsheimer JS. Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria. Genome Biol Evol. 2015 Dec 10; 7(12):3434-42. PMID: 26659922; PMCID: PMC4700952.
    28. Levine AJ, Soontornniyomkij V, Achim CL, Masliah E, Gelman BB, Sinsheimer JS, Singer EJ, Moore DJ. Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV. J Neurovirol. 2016 08; 22(4):431-41. PMID: 26637429.
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    29. Clark MM, Blangero J, Dyer TD, Sobel EM, Sinsheimer JS. The Quantitative-MFG Test: A Linear Mixed Effect Model to Detect Maternal-Offspring Gene Interactions. Ann Hum Genet. 2016 Jan; 80(1):63-80. PMID: 26567478.
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    30. Narayan S, Sinsheimer JS, Paul KC, Liew Z, Cockburn M, Bronstein JM, Ritz B. Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease. Environ Res. 2015 Nov; 143(Pt A):98-106. PMID: 26457621; PMCID: PMC4911423 [Available on 11/01/16].
    31. Paul KC, Sinsheimer JS, Rhodes SL, Cockburn M, Bronstein J, Ritz B. Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson's Disease, California (USA). Environ Health Perspect. 2016 05; 124(5):570-7. PMID: 26383258.
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    32. Gilbert PS, Chang J, Pan C, Sobel EM, Sinsheimer JS, Faircloth BC, Alfaro ME. Genome-wide ultraconserved elements exhibit higher phylogenetic informativeness than traditional gene markers in percomorph fishes. Mol Phylogenet Evol. 2015 Nov; 92:140-6. PMID: 26079130; PMCID: PMC4583375 [Available on 11/01/16].
    33. Cybis GB, Sinsheimer JS, Bedford T, Mather AE, Lemey P, Suchard MA. ASSESSING PHENOTYPIC CORRELATION THROUGH THE MULTIVARIATE PHYLOGENETIC LATENT LIABILITY MODEL. Ann Appl Stat. 2015 Jun; 9(2):969-991. PMID: 27053974.
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    34. Huertas-Vazquez A, Nelson CP, Sinsheimer JS, Reinier K, Uy-Evanado A, Teodorescu C, Ayala J, Hall AS, Gunson K, Jui J, Samani NJ, Chugh SS. Cumulative effects of common genetic variants on risk of sudden cardiac death. Int J Cardiol Heart Vasc. 2015 Jun 01; 7:88-91. PMID: 26114160.
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    35. Gatto NM, Sinsheimer JS, Cockburn M, Escobedo LA, Bordelon Y, Ritz B. Vitamin D receptor gene polymorphisms and Parkinson's disease in a population with high ultraviolet radiation exposure. J Neurol Sci. 2015 May 15; 352(1-2):88-93. PMID: 25890641; PMCID: PMC4478085.
    36. Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD. Acceleration of age-associated methylation patterns in HIV-1-infected adults. PLoS One. 2015; 10(3):e0119201. PMID: 25807146; PMCID: PMC4373843.
    37. Palmer CG, Boudreault P, Baldwin EE, Sinsheimer JS. Impact of genetic counseling and Connexin-26 and Connexin-30 testing on deaf identity and comprehension of genetic test results in a sample of deaf adults: a prospective, longitudinal study. PLoS One. 2014; 9(11):e111512. PMID: 25375116; PMCID: PMC4222828.
    38. Han E, Sinsheimer JS, Novembre J. Fast and accurate site frequency spectrum estimation from low coverage sequence data. Bioinformatics. 2015 Mar 01; 31(5):720-7. PMID: 25359894; PMCID: PMC4341071.
    39. Ngun TC, Ghahramani NM, Creek MM, Williams-Burris SM, Barseghyan H, Itoh Y, Sánchez FJ, McClusky R, Sinsheimer JS, Arnold AP, Vilain E. Feminized behavior and brain gene expression in a novel mouse model of Klinefelter Syndrome. Arch Sex Behav. 2014 Aug; 43(6):1043-57. PMID: 24923877; PMCID: PMC4371776.
    40. Anastasopoulos E, Coleman AL, Wilson MR, Sinsheimer JS, Yu F, Katafigiotis S, Founti P, Salonikiou A, Pappas T, Koskosas A, Katopodi T, Lambropoulos A, Topouzis F. Association of LOXL1 polymorphisms with pseudoexfoliation, glaucoma, intraocular pressure, and systemic diseases in a Greek population. The Thessaloniki eye study. Invest Ophthalmol Vis Sci. 2014 Jun 10; 55(7):4238-43. PMID: 24917141; PMCID: PMC4095722.
    41. Ko A, Cantor RM, Weissglas-Volkov D, Nikkola E, Reddy PM, Sinsheimer JS, Pasaniuc B, Brown R, Alvarez M, Rodriguez A, Rodriguez-Guillen R, Bautista IC, Arellano-Campos O, Muñoz-Hernández LL, Salomaa V, Kaprio J, Jula A, Jauhiainen M, Heliövaara M, Raitakari O, Lehtimäki T, Eriksson JG, Perola M, Lohmueller KE, Matikainen N, Taskinen MR, Rodriguez-Torres M, Riba L, Tusie-Luna T, Aguilar-Salinas CA, Pajukanta P. Amerindian-specific regions under positive selection harbour new lipid variants in Latinos. Nat Commun. 2014 Jun 02; 5:3983. PMID: 24886709; PMCID: PMC4062071.
    42. Arboleda VA, Fleming A, Barseghyan H, Délot E, Sinsheimer JS, Vilain E. Regulation of sex determination in mice by a non-coding genomic region. Genetics. 2014 Jul; 197(3):885-97. PMID: 24793290; PMCID: PMC4096368.
    43. Levine AJ, Reynolds S, Cox C, Miller EN, Sinsheimer JS, Becker JT, Martin E, Sacktor N. The longitudinal and interactive effects of HIV status, stimulant use, and host genotype upon neurocognitive functioning. J Neurovirol. 2014 Jun; 20(3):243-57. PMID: 24737013; PMCID: PMC4040160.
    44. Lange K, Papp JC, Sinsheimer JS, Sobel EM. Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data. Annu Rev Stat Appl. 2014 Jan 01; 1(1):279-300. PMID: 24955378.
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    45. Han E, Sinsheimer JS, Novembre J. Characterizing bias in population genetic inferences from low-coverage sequencing data. Mol Biol Evol. 2014 Mar; 31(3):723-35. PMID: 24288159; PMCID: PMC3935184.
    46. Kobayashi Y, Boudreault P, Hill K, Sinsheimer JS, Palmer CG. Using a social marketing framework to evaluate recruitment of a prospective study of genetic counseling and testing for the deaf community. BMC Med Res Methodol. 2013 Nov 25; 13:145. PMID: 24274380; PMCID: PMC3924226.
    47. Rhodes SL, Buchanan DD, Ahmed I, Taylor KD, Loriot MA, Sinsheimer JS, Bronstein JM, Elbaz A, Mellick GD, Rotter JI, Ritz B. Pooled analysis of iron-related genes in Parkinson's disease: association with transferrin. Neurobiol Dis. 2014 Feb; 62:172-8. PMID: 24121126; PMCID: PMC3968945.
    48. Narayan S, Liew Z, Paul K, Lee PC, Sinsheimer JS, Bronstein JM, Ritz B. Household organophosphorus pesticide use and Parkinson's disease. Int J Epidemiol. 2013 Oct; 42(5):1476-85. PMID: 24057998; PMCID: PMC3807617.
    49. Rhodes SL, Fitzmaurice AG, Cockburn M, Bronstein JM, Sinsheimer JS, Ritz B. Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson?s disease. Environ Res. 2013 Oct; 126:1-8. PMID: 23988235; PMCID: PMC3832349.
    50. Panos SE, Hinkin CH, Singer EJ, Thames AD, Patel SM, Sinsheimer JS, Del Re AC, Gelman BB, Morgello S, Moore DJ, Levine AJ. Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: the modulating effects of older age and disease severity. Neurobehav HIV Med. 2013; 5:11-22. PMID: 26617462.
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    51. Lange K, Papp JC, Sinsheimer JS, Sripracha R, Zhou H, Sobel EM. Mendel: the Swiss army knife of genetic analysis programs. Bioinformatics. 2013 Jun 15; 29(12):1568-70. PMID: 23610370; PMCID: PMC3673222.
    52. Lee PC, Rhodes SL, Sinsheimer JS, Bronstein J, Ritz B. Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure. Environ Int. 2013 Jun; 56:42-7. PMID: 23602893; PMCID: PMC3690300.
    53. Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Muñoz-Hernandez LL, Gomez-Munguia L, Ordoñez-Sánchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, Sinsheimer JS, Tusie-Luna T, Pajukanta P. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. J Med Genet. 2013 May; 50(5):298-308. PMID: 23505323; PMCID: PMC3917605.
    54. Palmer CG, Boudreault P, Baldwin EE, Fox M, Deignan JL, Kobayashi Y, Sininger Y, Grody W, Sinsheimer JS. Deaf genetic testing and psychological well-being in deaf adults. J Genet Couns. 2013 Aug; 22(4):492-507. PMID: 23430402; PMCID: PMC3701749.
    55. Cybis GB, Sinsheimer JS, Lemey P, Suchard MA. Graph hierarchies for phylogeography. Philos Trans R Soc Lond B Biol Sci. 2013 Mar 19; 368(1614):20120206. PMID: 23382428.
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    56. Lake JA, Sinsheimer JS. The deep roots of the rings of life. Genome Biol Evol. 2013; 5(12):2440-8. PMID: 24281049; PMCID: PMC3879980.
    57. Riley L, Zhou H, Lange K, Sinsheimer JS, Sehl ME. Determining duration of HER2-targeted therapy using stem cell extinction models. PLoS One. 2012; 7(12):e46613. PMID: 23284608; PMCID: PMC3532453.
    58. Reddy MV, Iatan I, Weissglas-Volkov D, Nikkola E, Haas BE, Juvonen M, Ruel I, Ruel MJ, Sinsheimer JS, Genest J, Pajukanta P. Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family. Circ Cardiovasc Genet. 2012 Oct 01; 5(5):538-46. PMID: 22923419; PMCID: PMC3515660.
    59. Anastasopoulos E, Kakoulidou A, Coleman AL, Sinsheimer JS, Wilson MR, Yu F, Salonikiou A, Koskosas A, Pappas T, Founti P, Lambropoulos A, Topouzis F. Association of sequence variation in the CX3CR1 gene with geographic atrophy age-related macular degeneration in a Greek population. Curr Eye Res. 2012 Dec; 37(12):1148-55. PMID: 22816662.
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    60. Sinsheimer JS, Little RJ, Lake JA. Rooting gene trees without outgroups: EP rooting. Genome Biol Evol. 2012; 4(8):709-19. PMID: 22593551; PMCID: PMC3509888.
    61. Tom JA, Sinsheimer JS, Suchard MA. Does history repeat itself? Wavelets and the phylodynamics of influenza A. Mol Biol Evol. 2012 May; 29(5):1367-77. PMID: 22160768.
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    62. Zhou JJ, Ghazalpour A, Sobel EM, Sinsheimer JS, Lange K. Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses. Genetics. 2012 Feb; 190(2):459-73. PMID: 22143921; PMCID: PMC3276647.
    63. Deere KA, Grether GF, Sun A, Sinsheimer JS. Female mate preference explains countergradient variation in the sexual coloration of guppies (Poecilia reticulata). Proc Biol Sci. 2012 May 07; 279(1734):1684-90. PMID: 22113030.
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    64. Levine AJ, Sinsheimer JS, Bilder R, Shapshak P, Singer EJ. Functional polymorphisms in dopamine-related genes: effect on neurocognitive functioning in HIV+ adults. J Clin Exp Neuropsychol. 2012; 34(1):78-91. PMID: 22082040.
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    65. Childs EJ, Sobel EM, Palmer CG, Sinsheimer JS. Detection of intergenerational genetic effects with application to HLA-B matching as a risk factor for schizophrenia. Hum Hered. 2011; 72(3):161-72. PMID: 22004985; PMCID: PMC3721948.
    66. Sehl M, Zhou H, Sinsheimer JS, Lange KL. Extinction models for cancer stem cell therapy. Math Biosci. 2011 Dec; 234(2):132-46. PMID: 22001354; PMCID: PMC3312607.
    67. Sinsheimer J. "Statistics 101"--a primer for the genetics of complex human disease. Cold Spring Harb Protoc. 2011 Oct 01; 2011(10):1190-9. PMID: 21969626.
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    68. Baldwin EE, Boudreault P, Fox M, Sinsheimer JS, Palmer CG. Effect of pre-test genetic counseling for deaf adults on knowledge of genetic testing. J Genet Couns. 2012 Apr; 21(2):256-72. PMID: 21818696; PMCID: PMC3313024.
    69. Weissglas-Volkov D, Calkin AC, Tusie-Luna T, Sinsheimer JS, Zelcer N, Riba L, Tino AM, Ordoñez-Sánchez ML, Cruz-Bautista I, Aguilar-Salinas CA, Tontonoz P, Pajukanta P. The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans. J Clin Invest. 2011 Aug; 121(8):3062-71. PMID: 21765216; PMCID: PMC3148733.
    70. Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. Epigenetic predictor of age. PLoS One. 2011; 6(6):e14821. PMID: 21731603; PMCID: PMC3120753.
    71. Ghazalpour A, Bennett B, Petyuk VA, Orozco L, Hagopian R, Mungrue IN, Farber CR, Sinsheimer J, Kang HM, Furlotte N, Park CC, Wen PZ, Brewer H, Weitz K, Camp DG, Pan C, Yordanova R, Neuhaus I, Tilford C, Siemers N, Gargalovic P, Eskin E, Kirchgessner T, Smith DJ, Smith RD, Lusis AJ. Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet. 2011 Jun; 7(6):e1001393. PMID: 21695224; PMCID: PMC3111477.
    72. Suwanwela J, Lee J, Lin A, Ucer TC, Devlin H, Sinsheimer J, Garrett NR, Nishimura I. A genetic association study of single nucleotide polymorphisms in FGFR1OP2/wit3.0 and long-term atrophy of edentulous mandible. PLoS One. 2011 Jan 19; 6(1):e16204. PMID: 21283824; PMCID: PMC3023796.
    73. Rhodes SL, Sinsheimer JS, Bordelon Y, Bronstein JM, Ritz B. Replication of GWAS associations for GAK and MAPT in Parkinson's disease. Ann Hum Genet. 2011 Mar; 75(2):195-200. PMID: 21058943; PMCID: PMC3074465.
    74. Zhou H, Sehl ME, Sinsheimer JS, Lange K. Association screening of common and rare genetic variants by penalized regression. Bioinformatics. 2010 Oct 01; 26(19):2375-82. PMID: 20693321; PMCID: PMC3025646.
    75. Sinsheimer JS, Elston RC, Fu WJ. Gene-gene interaction in maternal and perinatal research. J Biomed Biotechnol. 2010; 2010. PMID: 20798776; PMCID: PMC2926762.
    76. Childs EJ, Palmer CG, Lange K, Sinsheimer JS. Modeling maternal-offspring gene-gene interactions: the extended-MFG test. Genet Epidemiol. 2010 Jul; 34(5):512-21. PMID: 20552637; PMCID: PMC3165170.
    77. Boudreault P, Baldwin EE, Fox M, Dutton L, Tullis L, Linden J, Kobayashi Y, Zhou J, Sinsheimer JS, Sininger Y, Grody WW, Palmer CG. Deaf adults' reasons for genetic testing depend on cultural affiliation: results from a prospective, longitudinal genetic counseling and testing study. J Deaf Stud Deaf Educ. 2010; 15(3):209-27. PMID: 20488870; PMCID: PMC2902357.
    78. van Nas A, Ingram-Drake L, Sinsheimer JS, Wang SS, Schadt EE, Drake T, Lusis AJ. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics. 2010 Jul; 185(3):1059-68. PMID: 20439777; PMCID: PMC2907192.
    79. Cantor RM, Lange K, Sinsheimer JS. Prioritizing GWAS results: A review of statistical methods and recommendations for their application. Am J Hum Genet. 2010 Jan; 86(1):6-22. PMID: 20074509; PMCID: PMC2801749.
    80. Tom JA, Sinsheimer JS, Suchard MA. Reuse, Recycle, Reweigh: Combating Influenza through Efficient Sequential Bayesian Computation for Massive Data. Ann Appl Stat. 2010; 4(4):1722-1748. PMID: 26681992.
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    81. Sehl ME, Sinsheimer JS, Zhou H, Lange KL. Differential destruction of stem cells: implications for targeted cancer stem cell therapy. Cancer Res. 2009 Dec 15; 69(24):9481-9. PMID: 19996291; PMCID: PMC2844253.
    82. Weissglas-Volkov D, Aguilar-Salinas CA, Sinsheimer JS, Riba L, Huertas-Vazquez A, Ordoñez-Sánchez ML, Rodriguez-Guillen R, Cantor RM, Tusie-Luna T, Pajukanta P. Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circ Cardiovasc Genet. 2010 Feb; 3(1):31-8. PMID: 20160193; PMCID: PMC2827864.
    83. Weissglas-Volkov D, Plaisier CL, Huertas-Vazquez A, Cruz-Bautista I, Riaño-Barros D, Herrera-Hernandez M, Riba L, Cantor RM, Sinsheimer JS, Aguilar-Salinas CA, Tusie-Luna T, Pajukanta P. Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arterioscler Thromb Vasc Biol. 2010 Feb; 30(2):353-9. PMID: 19965785; PMCID: PMC2809779.
    84. Levine AJ, Singer EJ, Sinsheimer JS, Hinkin CH, Papp J, Dandekar S, Giovanelli A, Shapshak P. CCL3 genotype and current depression increase risk of HIV-associated dementia. Neurobehav HIV Med. 2009 Nov; 1:1-7. PMID: 20725607.
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    85. Meex SJ, Weissglas-Volkov D, van der Kallen CJ, Thuerauf DJ, van Greevenbroek MM, Schalkwijk CG, Stehouwer CD, Feskens EJ, Heldens L, Ayoubi TA, Hofker MH, Wouters BG, Vlietinck R, Sinsheimer JS, Taskinen MR, Kuusisto J, Laakso M, de Bruin TW, Pajukanta P, Glembotski CC. The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels. Arterioscler Thromb Vasc Biol. 2009 Sep; 29(9):1322-7. PMID: 19667116; PMCID: PMC2756089.
    86. Sinsheimer J. Statistical genetic approaches for mapping ophthalmic trait and disease genes. Am J Ophthalmol. 2009 Aug; 148(2):183-5. PMID: 19619719; PMCID: PMC2753187.
    87. Crandall CJ, Sehl ME, Crawford SL, Gold EB, Habel LA, Butler LM, Sowers MR, Greendale GA, Sinsheimer JS. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. Breast Cancer Res. 2009; 11(4):R51. PMID: 19630952; PMCID: PMC2750112.
    88. Zhou JJ, Lange K, Papp JC, Sinsheimer JS. A heterozygote-homozygote test of Hardy-Weinberg equilibrium. Eur J Hum Genet. 2009 Nov; 17(11):1495-500. PMID: 19367317; PMCID: PMC2986695.
    89. Sehl ME, Langer LR, Papp JC, Kwan L, Seldon JL, Arellano G, Reiss J, Reed EF, Dandekar S, Korin Y, Sinsheimer JS, Zhang ZF, Ganz PA. Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer. Clin Cancer Res. 2009 Mar 15; 15(6):2192-203. PMID: 19276285.
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    90. Plaisier CL, Kyttälä M, Weissglas-Volkov D, Sinsheimer JS, Huertas-Vazquez A, Riba L, Ramírez-Jiménez S, de Bruin TW, Tusié-Luna T, Aouizerat BE, Pullinger CR, Malloy MJ, Kane JP, Cruz-Bautista I, Herrera MF, Aguilar-Salinas C, Kuusisto J, Laakso M, Taskinen MR, van der Kallen CJ, Pajukanta P. Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler Thromb Vasc Biol. 2009 Jan; 29(1):147-52. PMID: 18988886; PMCID: PMC2650822.
    91. Bauman LE, Sinsheimer JS, Sobel EM, Lange K. Mixed effects models for quantitative trait loci mapping with inbred strains. Genetics. 2008 Nov; 180(3):1743-61. PMID: 18791243; PMCID: PMC2581972.
    92. Palmer CG, Mallery E, Turunen JA, Hsieh HJ, Peltonen L, Lonnqvist J, Woodward JA, Sinsheimer JS. Effect of Rhesus D incompatibility on schizophrenia depends on offspring sex. Schizophr Res. 2008 Sep; 104(1-3):135-45. PMID: 18692992.
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    93. Nikolova G, Sinsheimer JS, Eicher EM, Vilain E. The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice. Genetics. 2008 May; 179(1):419-27. PMID: 18458101; PMCID: PMC2390620.
    94. Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF. A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers. Int J Cancer. 2008 Apr 01; 122(7):1630-8. PMID: 18059021; PMCID: PMC2676936.
    95. Seitzman RL, Mahajan VB, Mangione C, Cauley JA, Ensrud KE, Stone KL, Cummings SR, Hochberg MC, Hillier TA, Sinsheimer JS, Yu F, Coleman AL. Estrogen receptor alpha and matrix metalloproteinase 2 polymorphisms and age-related maculopathy in older women. Am J Epidemiol. 2008 May 15; 167(10):1217-25. PMID: 18359774.
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    96. Sinsheimer JS, Plaisier CL, Huertas-Vazquez A, Aguilar-Salinas C, Tusie-Luna T, Pajukanta P, Lange K. Estimating ethnic admixture from pedigree data. Am J Hum Genet. 2008 Mar; 82(3):748-55. PMID: 18319077; PMCID: PMC2427215.
    97. Hsieh HJ, Palmer CG, Harney S, Chen HW, Bauman L, Brown MA, Sinsheimer JS. Using the maternal-fetal genotype incompatibility test to assess non-inherited maternal HLA-DRB1 antigen coding alleles as rheumatoid arthritis risk factors. BMC Proc. 2007; 1 Suppl 1:S124. PMID: 18466466; PMCID: PMC2367472.
    98. Lee JC, Weissglas-Volkov D, Kyttälä M, Sinsheimer JS, Jokiaho A, de Bruin TW, Lusis AJ, Brennan ML, van Greevenbroek MM, van der Kallen CJ, Hazen SL, Pajukanta P. USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arterioscler Thromb Vasc Biol. 2007 Oct; 27(10):2222-7. PMID: 17673701.
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    99. Wahner AD, Sinsheimer JS, Bronstein JM, Ritz B. Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease. Arch Neurol. 2007 Jun; 64(6):836-40. PMID: 17562931.
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    100. Loughlin J, Meulenbelt I, Min J, Mustafa Z, Sinsheimer JS, Carr A, Slagboom PE. Genetic association analysis of RHOB and TXNDC3 in osteoarthritis. Am J Hum Genet. 2007 Feb; 80(2):383-6; author reply 386-7. PMID: 17304710; PMCID: PMC1785353.
    101. Hsieh HJ, Palmer CG, Sinsheimer JS. Allowing for missing data at highly polymorphic genes when testing for maternal, offspring and maternal-fetal genotype incompatibility effects. Hum Hered. 2006; 62(3):165-74. PMID: 17065817.
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    102. Nikolova G, Lee H, Berkovitz S, Nelson S, Sinsheimer J, Vilain E, Rodríguez LV. Sequence variant in the laminin gamma1 (LAMC1) gene associated with familial pelvic organ prolapse. Hum Genet. 2007 Feb; 120(6):847-56. PMID: 17021862.
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    103. Kim S, Kim Y, Liang T, Sinsheimer JS, Chow SA. A high-throughput method for cloning and sequencing human immunodeficiency virus type 1 integration sites. J Virol. 2006 Nov; 80(22):11313-21. PMID: 16971446; PMCID: PMC1642152.
    104. Palmer CG, Hsieh HJ, Reed EF, Lonnqvist J, Peltonen L, Woodward JA, Sinsheimer JS. HLA-B maternal-fetal genotype matching increases risk of schizophrenia. Am J Hum Genet. 2006 Oct; 79(4):710-5. PMID: 16960807; PMCID: PMC1592576.
    105. Hsieh HJ, Palmer CG, Harney S, Newton JL, Wordsworth P, Brown MA, Sinsheimer JS. The v-MFG test: investigating maternal, offspring and maternal-fetal genetic incompatibility effects on disease and viability. Genet Epidemiol. 2006 May; 30(4):333-47. PMID: 16607625.
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    106. Mustafa Z, Dowling B, Chapman K, Sinsheimer JS, Carr A, Loughlin J. Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population. Arthritis Rheum. 2005 Nov; 52(11):3502-6. PMID: 16255042.
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    107. Suchard MA, Weiss RE, Sinsheimer JS. Models for estimating bayes factors with applications to phylogeny and tests of monophyly. Biometrics. 2005 Sep; 61(3):665-73. PMID: 16135017.
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    108. Lange K, Sinsheimer JS, Sobel E. Association testing with Mendel. Genet Epidemiol. 2005 Jul; 29(1):36-50. PMID: 15834862.
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    109. Kraft P, Hsieh HJ, Cordell HJ, Sinsheimer J. A conditional-on-exchangeable-parental-genotypes likelihood that remains unbiased at the causal locus under multiple-affected-sibling ascertainment. Genet Epidemiol. 2005 Jul; 29(1):87-90. PMID: 15712221.
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    110. Minassian SL, Palmer CG, Sinsheimer JS. An exact maternal-fetal genotype incompatibility (MFG) test. Genet Epidemiol. 2005 Jan; 28(1):83-95. PMID: 15368616.
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    111. Fang G, Kuiken C, Weiser B, Rowland-Jones S, Plummer F, Chen CH, Kaul R, Anzala AO, Bwayo J, Kimani J, Philpott SM, Kitchen C, Sinsheimer JS, Gaschen B, Lang D, Shi B, Kemal KS, Rostron T, Brunner C, Beddows S, Sattenau Q, Paxinos E, Oyugi J, Burger H. Long-term survivors in Nairobi: complete HIV-1 RNA sequences and immunogenetic associations. J Infect Dis. 2004 Aug 15; 190(4):697-701. PMID: 15272396.
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    112. Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ. Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ Res. 2004 Apr 16; 94(7):993-9. PMID: 15001527.
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    113. Kraft P, Palmer CG, Woodward AJ, Turunen JA, Minassian S, Paunio T, Lönnqvist J, Peltonen L, Sinsheimer JS. RHD maternal-fetal genotype incompatibility and schizophrenia: extending the MFG test to include multiple siblings and birth order. Eur J Hum Genet. 2004 Mar; 12(3):192-8. PMID: 14735156.
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    114. Pajukanta P, Lilja HE, Sinsheimer JS, Cantor RM, Lusis AJ, Gentile M, Duan XJ, Soro-Paavonen A, Naukkarinen J, Saarela J, Laakso M, Ehnholm C, Taskinen MR, Peltonen L. Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nat Genet. 2004 Apr; 36(4):371-6. PMID: 14991056.
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    115. Lange K, Sinsheimer JS. The pedigree trimming problem. Hum Hered. 2004; 58(2):108-11. PMID: 15711090.
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    116. Suchard MA, Kitchen CM, Sinsheimer JS, Weiss RE. Hierarchical phylogenetic models for analyzing multipartite sequence data. Syst Biol. 2003 Oct; 52(5):649-64. PMID: 14530132.
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    117. Duncan EL, Cardon LR, Sinsheimer JS, Wass JA, Brown MA. Site and gender specificity of inheritance of bone mineral density. J Bone Miner Res. 2003 Aug; 18(8):1531-8. PMID: 12929944.
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    118. Suchard MA, Weiss RE, Sinsheimer JS. Testing a molecular clock without an outgroup: derivations of induced priors on branch-length restrictions in a Bayesian framework. Syst Biol. 2003 Feb; 52(1):48-54. PMID: 12554439.
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    119. Sinsheimer JS, Suchard MA, Dorman KS, Fang F, Weiss RE. Are you my mother? Bayesian phylogenetic inference of recombination among putative parental strains. Appl Bioinformatics. 2003; 2(3):131-44. PMID: 15130798.
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    120. Sinsheimer JS, Palmer CG, Woodward JA. Detecting genotype combinations that increase risk for disease: maternal-fetal genotype incompatibility test. Genet Epidemiol. 2003 Jan; 24(1):1-13. PMID: 12508251.
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    121. Palmer CG, Turunen JA, Sinsheimer JS, Minassian S, Paunio T, Lönnqvist J, Peltonen L, Woodward JA. RHD maternal-fetal genotype incompatibility increases schizophrenia susceptibility. Am J Hum Genet. 2002 Dec; 71(6):1312-9. PMID: 12439825; PMCID: PMC378569.
    122. Suchard MA, Weiss RE, Dorman KS, Sinsheimer JS. Oh brother, where art thou? A Bayes factor test for recombination with uncertain heritage. Syst Biol. 2002 Oct; 51(5):715-28. PMID: 12396586.
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    123. Schadt EE, Sinsheimer JS, Lange K. Applications of codon and rate variation models in molecular phylogeny. Mol Biol Evol. 2002 Sep; 19(9):1550-62. PMID: 12200482.
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    124. Auranen M, Vanhala R, Varilo T, Ayers K, Kempas E, Ylisaukko-Oja T, Sinsheimer JS, Peltonen L, Järvelä I. A genomewide screen for autism-spectrum disorders: evidence for a major susceptibility locus on chromosome 3q25-27. Am J Hum Genet. 2002 Oct; 71(4):777-90. PMID: 12192642; PMCID: PMC378535.
    125. Dorman KS, Kaplan AH, Sinsheimer JS. Bootstrap confidence levels for HIV-1 recombination. J Mol Evol. 2002 Feb; 54(2):200-9. PMID: 11821913.
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