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Kaunitz Jonathan D.

TitleProfessor
InstitutionUniversity of California Los Angeles
DepartmentMedicine
AddressVA Greater LA Healthcare Sys Bldg 115
Los Angeles CA 90095
Phone310-268-4963
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Iwasaki M, Akiba Y, Kaunitz JD. Duodenal chemosensing. Curr Opin Gastroenterol. 2018 Aug 18. PMID: 30124472.
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    2. Bhattarai Y, Williams BB, Battaglioli EJ, Whitaker WR, Till L, Grover M, Linden DR, Akiba Y, Kandimalla KK, Zachos NC, Kaunitz JD, Sonnenburg JL, Fischbach MA, Farrugia G, Kashyap PC. Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe. 2018 Jun 13; 23(6):775-785.e5. PMID: 29902441.
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    3. Kaunitz JD. Magnetic Resonance Imaging: The Nuclear Option. Dig Dis Sci. 2018 May; 63(5):1100-1101. PMID: 29497905.
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    4. May FP, Yu C, Kaunitz J. High quality of cancer care in the Department of Veterans Affairs (VA). Am J Cancer Res. 2018; 8(4):761-762. PMID: 29736320.
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    5. Kaunitz JD, Akiba Y. A Tribute to Paul H. Guth, MD (1927-2017). Dig Dis Sci. 2018 Apr; 63(4):807-810. PMID: 29464586.
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    6. Akiba Y, Kaunitz JD. [Duodenal mucosal defense mechanisms;Current update on 'Duodenology']. Nihon Shokakibyo Gakkai Zasshi. 2018; 115(2):137-159. PMID: 29459558.
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    7. Kaji I, Kaunitz JD. Luminal chemosensing in the gastroduodenal mucosa. Curr Opin Gastroenterol. 2017 Nov; 33(6):439-445. PMID: 28806271.
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    8. Akiba Y, Maruta K, Narimatsu K, Said H, Kaji I, Kuri A, Iwamoto KI, Kuwahara A, Kaunitz JD. FFA2 activation combined with ulcerogenic COX inhibition induces duodenal mucosal injury via the 5-HT pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2017 Aug 01; 313(2):G117-G128. PMID: 28526687.
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    9. Said H, Akiba Y, Narimatsu K, Maruta K, Kuri A, Iwamoto KI, Kuwahara A, Kaunitz JD. FFA3 Activation Stimulates Duodenal Bicarbonate Secretion and Prevents NSAID-Induced Enteropathy via the GLP-2 Pathway in Rats. Dig Dis Sci. 2017 08; 62(8):1944-1952. PMID: 28523577.
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    10. Kaunitz JD. Development of Monoclonal Antibodies: The Dawn of mAb Rule. Dig Dis Sci. 2017 04; 62(4):831-832. PMID: 28181099.
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    11. Kaji I, Akiba Y, Kato I, Maruta K, Kuwahara A, Kaunitz JD. Xenin Augments Duodenal Anion Secretion via Activation of Afferent Neural Pathways. J Pharmacol Exp Ther. 2017 Apr; 361(1):151-161. PMID: 28115552.
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    12. Kaunitz JD. Welcome Associate Editors Ajay Goel, Aida Habtezion, and Walter Park. Dig Dis Sci. 2016 Nov; 61(11):3093-3094. PMID: 27696096.
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    13. Said H, Kaunitz JD. Gastrointestinal defense mechanisms. Curr Opin Gastroenterol. 2016 Nov; 32(6):461-466. PMID: 27653163.
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    14. Berg CJ, Kaunitz JD. Gut chemosensing: implications for disease pathogenesis. F1000Res. 2016; 5:2424. PMID: 27781093.
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    15. Kaunitz JD. DDS Elementary Style: A Brief Guide for Authors. Dig Dis Sci. 2016 08; 61(8):2147-50. PMID: 27312030.
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    16. Duboc H, Tolstanova G, Yuan PQ, Wu V, Kaji I, Biraud M, Akiba Y, Kaunitz J, Million M, Tache Y, Larauche M. Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT-777: role of submucosal neurons. Neurogastroenterol Motil. 2016 Nov; 28(11):1663-1676. PMID: 27259385.
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    17. Akiba Y, Kaunitz JD, Montrose MH. CFTR and pHi regulation. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1183. PMID: 27281734.
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    18. Kaji I, Akiba Y, Konno K, Watanabe M, Kimura S, Iwanaga T, Kuri A, Iwamoto K, Kuwahara A, Kaunitz JD. Neural FFA3 activation inversely regulates anion secretion evoked by nicotinic ACh receptor activation in rat proximal colon. J Physiol. 2016 06 15; 594(12):3339-52. PMID: 26854275; PMCID: PMC4908031 [Available on 06/15/17].
    19. Kaunitz JD. The Doppler Effect: A Century from Red Shift to Red Spot. Dig Dis Sci. 2016 Feb; 61(2):340-1. PMID: 26745970; PMCID: PMC4832914 [Available on 02/01/17].
    20. Said H, Kaji I, Kaunitz JD. Gastroduodenal mucosal defense mechanisms. Curr Opin Gastroenterol. 2015 Nov; 31(6):486-91. PMID: 26376476; PMCID: PMC4711914 [Available on 11/01/16].
    21. Kaunitz J, Nayyar P. Bugs, genes, fatty acids, and serotonin: Unraveling inflammatory bowel disease? F1000Res. 2015; 4. PMID: 27508055; PMCID: PMC4963018.
    22. Kaunitz AM, Kaunitz JD. Compounded bioidentical hormone therapy: time for a reality check? Menopause. 2015 Sep; 22(9):919-20. PMID: 26035149.
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    23. Kaunitz JD. The Discovery of PCR: ProCuRement of Divine Power. Dig Dis Sci. 2015 Aug; 60(8):2230-1. PMID: 26077976; PMCID: PMC4501591.
    24. Watanabe C, Komoto S, Tomita K, Hokari R, Tanaka M, Hirata I, Hibi T, Kaunitz JD, Miura S. Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. J Gastroenterol. 2016 Apr; 51(4):327-36. PMID: 26216651; PMCID: PMC4805704.
    25. Ahnen DJ, Bresalier RS, Levin B, Kaunitz JD. CRC screening, past, present, and future: a tribute to Emmet Keeffe. Dig Dis Sci. 2015 Mar; 60(3):589-91. PMID: 25724168; PMCID: PMC4428673.
    26. Sakanaka T, Inoue T, Yorifuji N, Iguchi M, Fujiwara K, Narabayashi K, Kakimoto K, Nouda S, Okada T, Kuramoto T, Ishida K, Abe Y, Takeuchi T, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. The effects of a TGR5 agonist and a dipeptidyl peptidase IV inhibitor on dextran sulfate sodium-induced colitis in mice. J Gastroenterol Hepatol. 2015 Mar; 30 Suppl 1:60-5. PMID: 25827806; PMCID: PMC4874188.
    27. Akiba Y, Kaunitz JD, Million M. Peripheral corticotropin-releasing factor receptor type 2 activation increases colonic blood flow through nitric oxide pathway in rats. Dig Dis Sci. 2015 Apr; 60(4):858-67. PMID: 25701320; PMCID: PMC4501405.
    28. Akiba Y, Inoue T, Kaji I, Higashiyama M, Narimatsu K, Iwamoto K, Watanabe M, Guth PH, Engel E, Kuwahara A, Kaunitz JD. Short-chain fatty acid sensing in rat duodenum. J Physiol. 2015 Feb 01; 593(3):585-99. PMID: 25433076; PMCID: PMC4324707.
    29. Fujiwara K, Inoue T, Yorifuji N, Iguchi M, Sakanaka T, Narabayashi K, Kakimoto K, Nouda S, Okada T, Ishida K, Abe Y, Masuda D, Takeuchi T, Fukunishi S, Umegaki E, Akiba Y, Kaunitz JD, Higuchi K. Combined treatment with dipeptidyl peptidase 4 (DPP4) inhibitor sitagliptin and elemental diets reduced indomethacin-induced intestinal injury in rats via the increase of mucosal glucagon-like peptide-2 concentration. J Clin Biochem Nutr. 2015 Mar; 56(2):155-62. PMID: 25759522; PMCID: PMC4345177.
    30. Akiba Y, Kaunitz JD. Prostaglandin pathways in duodenal chemosensing. J Gastroenterol Hepatol. 2014 Dec; 29 Suppl 4:93-8. PMID: 25521740; PMCID: PMC4451058.
    31. Kaji I, Iwanaga T, Watanabe M, Guth PH, Engel E, Kaunitz JD, Akiba Y. SCFA transport in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 01; 308(3):G188-97. PMID: 25394661; PMCID: PMC4312951.
    32. Kaunitz JD. The fruits of fiber: the invention of the flexible fiberoptic gastroscope. Dig Dis Sci. 2014 Nov; 59(11):2616-8. PMID: 25193388.
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    33. Kemmerly T, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2014 Nov; 30(6):583-8. PMID: 25229259; PMCID: PMC4238382.
    34. Kaunitz JD, Souza RF. Introduction to the "GRG profiles and perspectives" series. Dig Dis Sci. 2014 Sep; 59(9):2032. PMID: 25073957.
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    35. Rønnestad I, Akiba Y, Kaji I, Kaunitz JD. Duodenal luminal nutrient sensing. Curr Opin Pharmacol. 2014 Dec; 19:67-75. PMID: 25113991; PMCID: PMC4845631.
    36. Kaunitz JD. Priming the (proton) pump. Dig Dis Sci. 2014 Jul; 59(7):1356-7. PMID: 24627261; PMCID: PMC4844173.
    37. Kemmerly T, Vuong C, Kaunitz JD. A novel phosphorus repletion strategy in a patient with duodenal perforation. Nutr Clin Pract. 2014 Jun; 29(3):402-5. PMID: 24743045; PMCID: PMC4844180.
    38. Kaunitz JD. Paradigm shifts in perspective III: the discovery of tumor necrosis factor. Dig Dis Sci. 2014 Apr; 59(4):710-1. PMID: 24557574; PMCID: PMC4281172.
    39. Akiba Y, Kaunitz JD. Duodenal luminal chemosensing; acid, ATP, and nutrients. Curr Pharm Des. 2014; 20(16):2760-5. PMID: 23886391.
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    40. Inoue T, Higashiyama M, Kaji I, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats. Dig Dis Sci. 2014 Jun; 59(6):1286-95. PMID: 24379150; PMCID: PMC4196264.
    41. Ardecky RJ, Bobkova EV, Kiffer-Moreira T, Brown B, Ganji S, Zou J, Pass I, Narisawa S, Iano FG, Rosenstein C, Cheltsov A, Rascon J, Hedrick M, Gasior C, Forster A, Shi S, Dahl R, Vasile S, Su Y, Sergienko E, Chung TDY, Kaunitz J, Hoylaerts MF, Pinkerton AB, Millán JL. Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes. Bioorg Med Chem Lett. 2014 Feb 01; 24(3):1000-1004. PMID: 24412070; PMCID: PMC3943210.
    42. Kemmerly T, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2013 Nov; 29(6):642-9. PMID: 24100725.
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    43. Kaunitz JD. Bringing the Bacon home. Dig Dis Sci. 2013 Nov; 58(11):3070-1. PMID: 24122621; PMCID: PMC4281167.
    44. Soldavini J, Kaunitz JD. Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity. Dig Dis Sci. 2013 Oct; 58(10):2756-66. PMID: 23839339; PMCID: PMC4317286.
    45. Kaunitz JD. Introduction to the "paradigm shifts in perspective" series. Dig Dis Sci. 2013 Jul; 58(7):1825-6. PMID: 23756736; PMCID: PMC4327815.
    46. Kaunitz JD, Akiba Y. Wireless telemetry and cystic fibrosis: just the pHacts. Dig Dis Sci. 2013 Aug; 58(8):2129-30. PMID: 23748712; PMCID: PMC4197957.
    47. Souza RF, Kaunitz JD. Introduction to the "GRG Scholars Invited Reviews". Dig Dis Sci. 2013 May; 58(5):1175. PMID: 23579293; PMCID: PMC4847431.
    48. Palileo BM, Kaunitz JD. Covering digestive diseases and sciences: how to judge a journal by its cover. Dig Dis Sci. 2013 Mar; 58(3):592-5. PMID: 23504332.
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    49. Akiba Y, Kaunitz JD. May the truth be with you: lubiprostone as EP receptor agonist/ClC-2 internalizing "inhibitor". Dig Dis Sci. 2012 Nov; 57(11):2740-2. PMID: 23001408.
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    50. Al-Jiboury H, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2012 Nov; 28(6):594-601. PMID: 22954689.
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    51. Kaunitz JD. From bedside to bench: reverse engineering medical progress. Dig Dis Sci. 2012 Oct; 57(10):2481-3. PMID: 22983560; PMCID: PMC4281088.
    52. Inoue T, Wang JH, Higashiyama M, Rudenkyy S, Higuchi K, Guth PH, Engel E, Kaunitz JD, Akiba Y. Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid-induced bicarbonate secretion in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2012 Oct; 303(7):G810-6. PMID: 22821947; PMCID: PMC3469594.
    53. Palileo C, Kaunitz JD. Gastrointestinal defense mechanisms. Curr Opin Gastroenterol. 2011 Oct; 27(6):543-8. PMID: 21897225.
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    54. Wang JH, Inoue T, Higashiyama M, Guth PH, Engel E, Kaunitz JD, Akiba Y. Umami receptor activation increases duodenal bicarbonate secretion via glucagon-like peptide-2 release in rats. J Pharmacol Exp Ther. 2011 Nov; 339(2):464-73. PMID: 21846840; PMCID: PMC3199979.
    55. Hershcovici T, Poh CH, Fass OZ, Ashpole N, Akiba Y, Guillén-Rodríguez JM, Kaunitz JD, Fass R. Oesophageal sensation in response to high PCO(2) and acidic solutions in nonerosive reflux disease. Eur J Clin Invest. 2012 Feb; 42(2):195-202. PMID: 21679182.
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    56. Akiba Y, Kaunitz JD. Duodenal chemosensing and mucosal defenses. Digestion. 2011; 83 Suppl 1:25-31. PMID: 21389725; PMCID: PMC3202924.
    57. Kaunitz JD, Akiba Y. Purinergic regulation of duodenal surface pH and ATP concentration: implications for mucosal defence, lipid uptake and cystic fibrosis. Acta Physiol (Oxf). 2011 Jan; 201(1):109-16. PMID: 20560899; PMCID: PMC4196383.
    58. Akiba Y, Kaunitz JD. Duodenal chemosensing: master control for epigastric sensation? J Gastroenterol Hepatol. 2011 Jan; 26(1):6-7. PMID: 21073675.
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    59. Goo T, Akiba Y, Kaunitz JD. Mechanisms of intragastric pH sensing. Curr Gastroenterol Rep. 2010 Dec; 12(6):465-70. PMID: 20938760; PMCID: PMC2974196.
    60. deFoneska A, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2010 Nov; 26(6):604-10. PMID: 20948371.
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    61. Akiba Y, Kaunitz JD. Lafutidine, a protective H2 receptor antagonist, enhances mucosal defense in rat esophagus. Dig Dis Sci. 2010 Nov; 55(11):3063-9. PMID: 20824506; PMCID: PMC2958262.
    62. Ham M, Mizumori M, Watanabe C, Wang JH, Inoue T, Nakano T, Guth PH, Engel E, Kaunitz JD, Akiba Y. Endogenous luminal surface adenosine signaling regulates duodenal bicarbonate secretion in rats. J Pharmacol Exp Ther. 2010 Dec; 335(3):607-13. PMID: 20805305; PMCID: PMC2993549.
    63. Bergmann LL, Zimmerman P, Kaunitz JD. Unusual complication: superior mesenteric artery syndrome and closed loop gastroduodenal obstruction after adjustable gastric banding. Surg Obes Relat Dis. 2011 Mar-Apr; 7(2):237-9. PMID: 21130049.
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    64. Zhu A, Kaneshiro M, Kaunitz JD. Evaluation and treatment of iron deficiency anemia: a gastroenterological perspective. Dig Dis Sci. 2010 Mar; 55(3):548-59. PMID: 20108038; PMCID: PMC2822907.
    65. deFonseka A, Kaunitz J. Gut sensing mechanisms. Curr Gastroenterol Rep. 2009 Dec; 11(6):442-7. PMID: 19903419.
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    66. Nayeb-Hashemi H, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2009 Nov; 25(6):537-43. PMID: 19654540.
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    67. Mizumori M, Akiba Y, Kaunitz JD. Lubiprostone stimulates duodenal bicarbonate secretion in rats. Dig Dis Sci. 2009 Oct; 54(10):2063-9. PMID: 19657734; PMCID: PMC2737111.
    68. Akiba Y, Watanabe C, Mizumori M, Kaunitz JD. Luminal L-glutamate enhances duodenal mucosal defense mechanisms via multiple glutamate receptors in rats. Am J Physiol Gastrointest Liver Physiol. 2009 Oct; 297(4):G781-91. PMID: 19643955; PMCID: PMC2763813.
    69. Akiba Y, Kaunitz JD. Luminal chemosensing and upper gastrointestinal mucosal defenses. Am J Clin Nutr. 2009 Sep; 90(3):826S-831S. PMID: 19571224; PMCID: PMC3136009.
    70. Mizumori M, Ham M, Guth PH, Engel E, Kaunitz JD, Akiba Y. Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum. J Physiol. 2009 Jul 15; 587(Pt 14):3651-63. PMID: 19451200; PMCID: PMC2742288.
    71. Nakano T, Inoue I, Alpers DH, Akiba Y, Katayama S, Shinozaki R, Kaunitz JD, Ohshima S, Akita M, Takahashi S, Koyama I, Matsushita M, Komoda T. Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration. Am J Physiol Gastrointest Liver Physiol. 2009 Jul; 297(1):G207-14. PMID: 19407215; PMCID: PMC3817256.
    72. Zhu A, Kaunitz J. Gastroduodenal mucosal defense. Curr Gastroenterol Rep. 2008 Dec; 10(6):548-54. PMID: 19006609.
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    73. Ham M, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2008 Nov; 24(6):665-73. PMID: 19122513.
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    74. Kaunitz JD, Yamaguchi DT. TNAP, TrAP, ecto-purinergic signaling, and bone remodeling. J Cell Biochem. 2008 Oct 15; 105(3):655-62. PMID: 18773425.
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    75. Mizumori M, Choi Y, Guth PH, Engel E, Kaunitz JD, Akiba Y. CFTR inhibition augments NHE3 activity during luminal high CO2 exposure in rat duodenal mucosa. Am J Physiol Gastrointest Liver Physiol. 2008 Jun; 294(6):G1318-27. PMID: 18420826.
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    76. Guth PH, Kaunitz JD. Personal reminiscences about Morton Grossman and the founding of the Center for Ulcer Research and Education (CURE). Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1109-13. PMID: 18356532.
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    77. Ham M, Kaunitz JD. Gastroduodenal defense. Curr Opin Gastroenterol. 2007 Nov; 23(6):607-16. PMID: 17906436.
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    78. Akiba Y, Mizumori M, Guth PH, Engel E, Kaunitz JD. Duodenal brush border intestinal alkaline phosphatase activity affects bicarbonate secretion in rats. Am J Physiol Gastrointest Liver Physiol. 2007 Dec; 293(6):G1223-33. PMID: 17916646.
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    79. Ham M, Horton K, Kaunitz J. Fistuloclysis: case report and literature review. Nutr Clin Pract. 2007 Oct; 22(5):553-7. PMID: 17906279.
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    80. Minagawa N, Nagata J, Shibao K, Masyuk AI, Gomes DA, Rodrigues MA, Lesage G, Akiba Y, Kaunitz JD, Ehrlich BE, Larusso NF, Nathanson MH. Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile. Gastroenterology. 2007 Nov; 133(5):1592-602. PMID: 17916355; PMCID: PMC2128713.
    81. Kaunitz JD. NKCC1: tales from the dark side of the crypt. J Physiol. 2007 Jul 15; 582(Pt 2):477. PMID: 17525110; PMCID: PMC2075318.
    82. Smith JP, Dong MH, Kaunitz JD. Evaluation of a pharmacist-managed hepatitis C care clinic. Am J Health Syst Pharm. 2007 Mar 15; 64(6):632-6. PMID: 17353572.
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    83. Kaunitz JD, Akiba Y. Review article: duodenal bicarbonate - mucosal protection, luminal chemosensing and acid-base balance. Aliment Pharmacol Ther. 2006 Dec; 24 Suppl 4:169-76. PMID: 17209861.
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    84. Dong MH, Kaunitz JD. Gastroduodenal mucosal defense. Curr Opin Gastroenterol. 2006 Nov; 22(6):599-606. PMID: 17053436.
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    85. Kaunitz JD, Akiba Y. Duodenal carbonic anhydrase: mucosal protection, luminal chemosensing, and gastric acid disposal. Keio J Med. 2006 Sep; 55(3):96-106. PMID: 17008801.
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    86. Akiba Y, Ghayouri S, Takeuchi T, Mizumori M, Guth PH, Engel E, Swenson ER, Kaunitz JD. Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum. Gastroenterology. 2006 Jul; 131(1):142-52. PMID: 16831598.
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    87. Kaunitz JD. Membrane transport proteins: not just for transport anymore. Am J Physiol Renal Physiol. 2006 May; 290(5):F995-6. PMID: 16601299.
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    88. Mizumori M, Meyerowitz J, Takeuchi T, Lim S, Lee P, Supuran CT, Guth PH, Engel E, Kaunitz JD, Akiba Y. Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa. J Physiol. 2006 Jun 15; 573(Pt 3):827-42. PMID: 16556652; PMCID: PMC1779739.
    89. Akiba Y, Jung M, Ouk S, Kaunitz JD. A novel small molecule CFTR inhibitor attenuates HCO3- secretion and duodenal ulcer formation in rats. Am J Physiol Gastrointest Liver Physiol. 2005 Oct; 289(4):G753-9. PMID: 15905414.
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    90. Kawakubo K, Akiba Y, Adelson D, Guth PH, Engel E, Taché Y, Kaunitz JD. Role of gastric mast cells in the regulation of central TRH analog-induced hyperemia in rats. Peptides. 2005 Sep; 26(9):1580-9. PMID: 16112396.
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    91. Kaunitz JD, Akiba Y. Gastroduodenal mucosal defense: role of endogenous mediators. Curr Opin Gastroenterol. 2004 Nov; 20(6):526-32. PMID: 15703677.
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    92. Furukawa O, Hirokawa M, Zhang L, Takeuchi T, Bi LC, Guth PH, Engel E, Akiba Y, Kaunitz JD. Mechanism of augmented duodenal HCO(3)(-) secretion after elevation of luminal CO(2). Am J Physiol Gastrointest Liver Physiol. 2005 Mar; 288(3):G557-63. PMID: 15499081.
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    93. Hirokawa M, Takeuchi T, Chu S, Akiba Y, Wu V, Guth PH, Engel E, Montrose MH, Kaunitz JD. Cystic fibrosis gene mutation reduces epithelial cell acidification and injury in acid-perfused mouse duodenum. Gastroenterology. 2004 Oct; 127(4):1162-73. PMID: 15480994.
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    94. Hirokawa M, Furukawa O, Guth PH, Engel E, Kaunitz JD. Low-dose PGE2 mimics the duodenal secretory response to luminal acid in mice. Am J Physiol Gastrointest Liver Physiol. 2004 Jun; 286(6):G891-8. PMID: 14764447.
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    95. Kaunitz JD, Akiba Y. Acid-sensing protective mechanisms of duodenum. J Physiol Pharmacol. 2003 Dec; 54 Suppl 4:19-26. PMID: 15075446.
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    96. Bi LC, Kaunitz JD. Gastroduodenal mucosal defense: an integrated protective response. Curr Opin Gastroenterol. 2003 Nov; 19(6):526-32. PMID: 15703600.
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    97. Furukawa O, Bi LC, Guth PH, Engel E, Hirokawa M, Kaunitz JD. NHE3 inhibition activates duodenal bicarbonate secretion in the rat. Am J Physiol Gastrointest Liver Physiol. 2004 Jan; 286(1):G102-9. PMID: 12881227.
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    98. Furukawa O, Hirokawa M, Guth PH, Engel E, Kaunitz JD. Role of protein kinases on acid-induced duodenal bicarbonate secretion in rats. Pharmacology. 2003 Feb; 67(2):99-105. PMID: 12566854.
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    99. Akiba Y, Nakamura M, Nagata H, Kaunitz JD, Ishii H. Acid-sensing pathways in rat gastrointestinal mucosa. J Gastroenterol. 2002 Nov; 37 Suppl 14:133-8. PMID: 12572881.
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    100. Guha S, Kaunitz JD. Gastroduodenal mucosal defense: an integrated protective response. Curr Opin Gastroenterol. 2002 Nov; 18(6):650-7. PMID: 17033343.
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    101. Kaunitz JD, Akiba Y. Luminal acid elicits a protective duodenal mucosal response. Keio J Med. 2002 Mar; 51(1):29-35. PMID: 11951376.
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    102. Kaunitz JD, Akiba Y. Integrated duodenal protective response to acid. Life Sci. 2001 Nov 09; 69(25-26):3073-81. PMID: 11758832.
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    103. Kaunitz JD, Akiba Y. Duodenal intracellular bicarbonate and the 'CF paradox'. JOP. 2001 Jul; 2(4 Suppl):268-73. PMID: 11875270.
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    104. Kaunitz JD. Barrier function of gastric mucus. Keio J Med. 1999 Jun; 48(2):63-8. PMID: 10405521.
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