Loading...

Feigon Juli

TitleLab Director
InstitutionUniversity of California Los Angeles
DepartmentFeigon Lab
Address607 Charles Young Dr. East
P.O. Box 951569
Los Angeles CA 90095
Phone1 (310) 206-3493
vCardDownload vCard
    Other Positions
    TitleProfessor

    TitleProfessor

    TitleStaff

    TitleStaff


    Collapse Research 
    Collapse Research Activities and Funding
    800 MHz NMR Console and Cryoprobe Replacement
    NIH S10OD025073Mar 6, 2018 - Mar 5, 2019
    Role: Principal Investigator
    Structure and Assembly of Regulatory RNPs
    NIH/NIGMS R01GM107567Sep 1, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Frontiers in NMR: A Celebration of the UCLA MRR
    NIH/NCRR R13RR019123Sep 30, 2003 - Sep 29, 2004
    Role: Principal Investigator
    PURCHASE OF 600MHZ NMR SPECTROMETER
    NIH/NCRR S10RR015754May 1, 2001 - Apr 30, 2002
    Role: Principal Investigator
    1995 GORDON CONFERENCE ON NUCLEIC ACIDS
    NIH/NIGMS R13GM053223Jun 1, 1995 - May 31, 1996
    Role: Principal Investigator
    Structure and Function of Human Telomerase
    NIH/NIGMS R01GM048123Aug 1, 1992 - Aug 31, 2019
    Role: Principal Investigator
    Conformational Variability of RNA
    NIH/NIGMS R01GM037254Jul 1, 1986 - Jun 30, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Eichhorn CD, Yang Y, Repeta L, Feigon J. Structural basis for recognition of human 7SK long noncoding RNA by the La-related protein Larp7. Proc Natl Acad Sci U S A. 2018 Jun 26. PMID: 29946027.
      View in: PubMed
    2. Jiang J, Wang Y, Sušac L, Chan H, Basu R, Zhou ZH, Feigon J. Structure of Telomerase with Telomeric DNA. Cell. 2018 May 17; 173(5):1179-1190.e13. PMID: 29775593.
      View in: PubMed
    3. Wang Y, Feigon J. Structural biology of telomerase and its interaction at telomeres. Curr Opin Struct Biol. 2017 12; 47:77-87. PMID: 28732250.
      View in: PubMed
    4. Chan H, Wang Y, Feigon J. Progress in Human and Tetrahymena Telomerase Structure Determination. Annu Rev Biophys. 2017 May 22; 46:199-225. PMID: 28301767.
      View in: PubMed
    5. Cash DD, Feigon J. Structure and folding of the Tetrahymena telomerase RNA pseudoknot. Nucleic Acids Res. 2017 Jan 09; 45(1):482-495. PMID: 27899638.
      View in: PubMed
    6. Upton HE, Chan H, Feigon J, Collins K. Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes. J Biol Chem. 2017 Jan 06; 292(1):217-228. PMID: 27895115.
      View in: PubMed
    7. Eichhorn CD, Chug R, Feigon J. hLARP7 C-terminal domain contains an xRRM that binds the 3' hairpin of 7SK RNA. Nucleic Acids Res. 2016 Nov 16; 44(20):9977-9989. PMID: 27679474.
      View in: PubMed
    8. Wang Y, Yesselman JD, Zhang Q, Kang M, Feigon J. Structural conservation in the template/pseudoknot domain of vertebrate telomerase RNA from teleost fish to human. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):E5125-34. PMID: 27531956.
      View in: PubMed
    9. Feigon J, Chan H, Jiang J. Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres. FEBS J. 2016 06; 283(11):2044-50. PMID: 26918633; PMCID: PMC4899323 [Available on 06/01/17].
    10. Jiang J, Chan H, Cash DD, Miracco EJ, Ogorzalek Loo RR, Upton HE, Cascio D, O'Brien Johnson R, Collins K, Loo JA, Zhou ZH, Feigon J. Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science. 2015 Oct 30; 350(6260):aab4070. PMID: 26472759; PMCID: PMC4687456.
    11. Feigon J. Back to the future of RNA structure. RNA. 2015 Apr; 21(4):611-2. PMID: 25780161; PMCID: PMC4371303.
    12. Singh M, Wang Z, Cascio D, Feigon J. Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1. J Mol Biol. 2015 Feb 27; 427(4):807-823. PMID: 25553844.
      View in: PubMed
    13. Eichhorn CD, Kang M, Feigon J. Structure and function of preQ1 riboswitches. Biochim Biophys Acta. 2014 Oct; 1839(10):939-950. PMID: 24798077.
      View in: PubMed
    14. Miracco EJ, Jiang J, Cash DD, Feigon J. Progress in structural studies of telomerase. Curr Opin Struct Biol. 2014 Feb; 24:115-24. PMID: 24508601; PMCID: PMC3984607.
    15. Kang M, Eichhorn CD, Feigon J. Structural determinants for ligand capture by a class II preQ1 riboswitch. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):E663-71. PMID: 24469808; PMCID: PMC3926045.
    16. Kim NK, Zhang Q, Feigon J. Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function. Nucleic Acids Res. 2014 Mar; 42(5):3395-408. PMID: 24335084; PMCID: PMC3950677.
    17. Shen K, Wang Y, Hwang Fu YH, Zhang Q, Feigon J, Shan SO. Molecular mechanism of GTPase activation at the signal recognition particle (SRP) RNA distal end. J Biol Chem. 2013 Dec 20; 288(51):36385-97. PMID: 24151069; PMCID: PMC3868752.
    18. Hong K, Upton H, Miracco EJ, Jiang J, Zhou ZH, Feigon J, Collins K. Tetrahymena telomerase holoenzyme assembly, activation, and inhibition by domains of the p50 central hub. Mol Cell Biol. 2013 Oct; 33(19):3962-71. PMID: 23918804; PMCID: PMC3811867.
    19. Cash DD, Cohen-Zontag O, Kim NK, Shefer K, Brown Y, Ulyanov NB, Tzfati Y, Feigon J. Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):10970-5. PMID: 23776224; PMCID: PMC3704002.
    20. Jiang J, Miracco EJ, Hong K, Eckert B, Chan H, Cash DD, Min B, Zhou ZH, Collins K, Feigon J. The architecture of Tetrahymena telomerase holoenzyme. Nature. 2013 Apr 11; 496(7444):187-92. PMID: 23552895; PMCID: PMC3817743.
    21. Singh M, Choi CP, Feigon J. xRRM: a new class of RRM found in the telomerase La family protein p65. RNA Biol. 2013 Mar; 10(3):353-9. PMID: 23328630; PMCID: PMC3672277.
    22. Hartman E, Wang Z, Zhang Q, Roy K, Chanfreau G, Feigon J. Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites. J Mol Biol. 2013 Feb 08; 425(3):546-62. PMID: 23201338; PMCID: PMC3557707.
    23. Kang M, Heuberger B, Chaput JC, Switzer C, Feigon J. Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4 T) in the presence of Cs+ ions. Angew Chem Int Ed Engl. 2012 Aug 06; 51(32):7952-5. PMID: 22767484.
      View in: PubMed
    24. Singh M, Wang Z, Koo BK, Patel A, Cascio D, Collins K, Feigon J. Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mol Cell. 2012 Jul 13; 47(1):16-26. PMID: 22705372; PMCID: PMC3398246.
    25. Hengesbach M, Kim NK, Feigon J, Stone MD. Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain. Angew Chem Int Ed Engl. 2012 Jun 11; 51(24):5876-9. PMID: 22544760; PMCID: PMC3483790.
    26. Zhang Q, Kim NK, Feigon J. Architecture of human telomerase RNA. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20325-32. PMID: 21844345; PMCID: PMC3251123.
    27. Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J. Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs. Structure. 2011 Jul 13; 19(7):999-1010. PMID: 21742266; PMCID: PMC3143303.
    28. Koo BK, Park CJ, Fernandez CF, Chim N, Ding Y, Chanfreau G, Feigon J. Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. J Mol Biol. 2011 Sep 02; 411(5):927-42. PMID: 21708174; PMCID: PMC3156286.
    29. Zhang Q, Kang M, Peterson RD, Feigon J. Comparison of solution and crystal structures of preQ1 riboswitch reveals calcium-induced changes in conformation and dynamics. J Am Chem Soc. 2011 Apr 13; 133(14):5190-3. PMID: 21410253; PMCID: PMC3085290.
    30. Zhang Q, Kim NK, Peterson RD, Wang Z, Feigon J. Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):18761-8. PMID: 20966348; PMCID: PMC2973926.
    31. Kim NK, Theimer CA, Mitchell JR, Collins K, Feigon J. Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res. 2010 Oct; 38(19):6746-56. PMID: 20554853; PMCID: PMC2965242.
    32. Kang M, Peterson R, Feigon J. Structural Insights into riboswitch control of the biosynthesis of queuosine, a modified nucleotide found in the anticodon of tRNA. Mol Cell. 2009 Mar 27; 33(6):784-90. PMID: 19285444.
      View in: PubMed
    33. Singh M, Gonzales FA, Cascio D, Heckmann N, Chanfreau G, Feigon J. Structure and functional studies of the CS domain of the essential H/ACA ribonucleoparticle assembly protein SHQ1. J Biol Chem. 2009 Jan 16; 284(3):1906-16. PMID: 19019820; PMCID: PMC2615527.
    34. Kim NK, Zhang Q, Zhou J, Theimer CA, Peterson RD, Feigon J. Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA. J Mol Biol. 2008 Dec 31; 384(5):1249-61. PMID: 18950640; PMCID: PMC2660571.
    35. Theimer CA, Jády BE, Chim N, Richard P, Breece KE, Kiss T, Feigon J. Structural and functional characterization of human telomerase RNA processing and cajal body localization signals. Mol Cell. 2007 Sep 21; 27(6):869-81. PMID: 17889661.
      View in: PubMed
    36. Januszyk K, Li PW, Villareal V, Branciforte D, Wu H, Xie Y, Feigon J, Loo JA, Martin SL, Clubb RT. Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1. J Biol Chem. 2007 Aug 24; 282(34):24893-904. PMID: 17569664.
      View in: PubMed
    37. Wu H, Feigon J. H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6655-60. PMID: 17412831; PMCID: PMC1871841.
    38. Richards RJ, Wu H, Trantirek L, O'Connor CM, Collins K, Feigon J. Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. RNA. 2006 Aug; 12(8):1475-85. PMID: 16809815; PMCID: PMC1524899.
    39. Theimer CA, Feigon J. Structure and function of telomerase RNA. Curr Opin Struct Biol. 2006 Jun; 16(3):307-18. PMID: 16713250.
      View in: PubMed
    40. Richards RJ, Theimer CA, Finger LD, Feigon J. Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element. Nucleic Acids Res. 2006; 34(3):816-25. PMID: 16452301; PMCID: PMC1360744.
    41. Khanna M, Wu H, Johansson C, Caizergues-Ferrer M, Feigon J. Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA. RNA. 2006 Jan; 12(1):40-52. PMID: 16373493; PMCID: PMC1370884.
    42. Dingley AJ, Peterson RD, Grzesiek S, Feigon J. Characterization of the cation and temperature dependence of DNA quadruplex hydrogen bond properties using high-resolution NMR. J Am Chem Soc. 2005 Oct 19; 127(41):14466-72. PMID: 16218642.
      View in: PubMed
    43. Qin PZ, Feigon J, Hubbell WL. Site-directed spin labeling studies reveal solution conformational changes in a GAAA tetraloop receptor upon Mg(2+)-dependent docking of a GAAA tetraloop. J Mol Biol. 2005 Aug 05; 351(1):1-8. PMID: 15993422.
      View in: PubMed
    44. Henras AK, Sam M, Hiley SL, Wu H, Hughes TR, Feigon J, Chanfreau GF. Biochemical and genomic analysis of substrate recognition by the double-stranded RNA binding domain of yeast RNase III. RNA. 2005 Aug; 11(8):1225-37. PMID: 15987808; PMCID: PMC1370806.
    45. Theimer CA, Blois CA, Feigon J. Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function. Mol Cell. 2005 Mar 04; 17(5):671-82. PMID: 15749017.
      View in: PubMed
    46. Wu H, Finger LD, Feigon J. Structure determination of protein/RNA complexes by NMR. Methods Enzymol. 2005; 394:525-45. PMID: 15808236.
      View in: PubMed
    47. Kamionka M, Feigon J. Structure of the XPC binding domain of hHR23A reveals hydrophobic patches for protein interaction. Protein Sci. 2004 Sep; 13(9):2370-7. PMID: 15322280; PMCID: PMC2280024.
    48. Finger LD, Johansson C, Rinaldi B, Bouvet P, Feigon J. Contributions of the RNA-binding and linker domains and RNA structure to the specificity and affinity of the nucleolin RBD12/NRE interaction. Biochemistry. 2004 Jun 08; 43(22):6937-47. PMID: 15170331.
      View in: PubMed
    49. Wu H, Henras A, Chanfreau G, Feigon J. Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III. Proc Natl Acad Sci U S A. 2004 Jun 01; 101(22):8307-12. PMID: 15150409; PMCID: PMC420390.
    50. Johansson C, Finger LD, Trantirek L, Mueller TD, Kim S, Laird-Offringa IA, Feigon J. Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target. J Mol Biol. 2004 Apr 02; 337(4):799-816. PMID: 15033352.
      View in: PubMed
    51. Stefl R, Wu H, Ravindranathan S, Sklenár V, Feigon J. DNA A-tract bending in three dimensions: solving the dA4T4 vs. dT4A4 conundrum. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1177-82. PMID: 14739342; PMCID: PMC337026.
    52. Mueller TD, Kamionka M, Feigon J. Specificity of the interaction between ubiquitin-associated domains and ubiquitin. J Biol Chem. 2004 Mar 19; 279(12):11926-36. PMID: 14707125.
      View in: PubMed
    53. Peterson RD, Theimer CA, Wu H, Feigon J. New applications of 2D filtered/edited NOESY for assignment and structure elucidation of RNA and RNA-protein complexes. J Biomol NMR. 2004 Jan; 28(1):59-67. PMID: 14739639.
      View in: PubMed
    54. Theimer CA, Finger LD, Feigon J. YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA. RNA. 2003 Dec; 9(12):1446-55. PMID: 14624001; PMCID: PMC1370499.
    55. Finger LD, Trantirek L, Johansson C, Feigon J. Solution structures of stem-loop RNAs that bind to the two N-terminal RNA-binding domains of nucleolin. Nucleic Acids Res. 2003 Nov 15; 31(22):6461-72. PMID: 14602904; PMCID: PMC275560.
    56. Mueller TD, Feigon J. Structural determinants for the binding of ubiquitin-like domains to the proteasome. EMBO J. 2003 Sep 15; 22(18):4634-45. PMID: 12970176; PMCID: PMC212733.
    57. Qin PZ, Hideg K, Feigon J, Hubbell WL. Monitoring RNA base structure and dynamics using site-directed spin labeling. Biochemistry. 2003 Jun 10; 42(22):6772-83. PMID: 12779332.
      View in: PubMed
    58. Theimer CA, Finger LD, Trantirek L, Feigon J. Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):449-54. PMID: 12525685; PMCID: PMC141015.
    59. Masse JE, Wong B, Yen YM, Allain FH, Johnson RC, Feigon J. The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding. J Mol Biol. 2002 Oct 18; 323(2):263-84. PMID: 12381320.
      View in: PubMed
    60. Hud NV, Feigon J. Characterization of divalent cation localization in the minor groove of the A(n)T(n) and T(n)A(n) DNA sequence elements by (1)H NMR spectroscopy and manganese(II). Biochemistry. 2002 Aug 06; 41(31):9900-10. PMID: 12146955.
      View in: PubMed
    61. Mueller TD, Feigon J. Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions. J Mol Biol. 2002 Jun 21; 319(5):1243-55. PMID: 12079361.
      View in: PubMed
    62. Trantírek L, Stefl R, Masse JE, Feigon J, Sklenár V. Determination of the glycosidic torsion angles in uniformly 13C-labeled nucleic acids from vicinal coupling constants 3J(C2)/4-H1' and 3J(C6)/8-H1'. J Biomol NMR. 2002 May; 23(1):1-12. PMID: 12061713.
      View in: PubMed
    63. Wong B, Masse JE, Yen YM, Giannikopoulos P, Feigon J, Johnson RC, Giannikoupolous P. Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A. Biochemistry. 2002 Apr 30; 41(17):5404-14. PMID: 11969400.
      View in: PubMed
    64. Wu H, Yang PK, Butcher SE, Kang S, Chanfreau G, Feigon J. A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J. 2001 Dec 17; 20(24):7240-9. PMID: 11743000; PMCID: PMC125782.
    65. Zídek L, Wu H, Feigon J, Sklenár V. Measurement of small scalar and dipolar couplings in purine and pyrimidine bases. J Biomol NMR. 2001 Oct; 21(2):153-60. PMID: 11727978.
      View in: PubMed
    66. Qin PZ, Butcher SE, Feigon J, Hubbell WL. Quantitative analysis of the isolated GAAA tetraloop/receptor interaction in solution: a site-directed spin labeling study. Biochemistry. 2001 Jun 12; 40(23):6929-36. PMID: 11389608.
      View in: PubMed
    67. Bouvet P, Allain FH, Finger LD, Dieckmann T, Feigon J. Recognition of pre-formed and flexible elements of an RNA stem-loop by nucleolin. J Mol Biol. 2001 Jun 08; 309(3):763-75. PMID: 11397095.
      View in: PubMed
    68. Barfield M, Dingley AJ, Feigon J, Grzesiek S. A DFT study of the interresidue dependencies of scalar J-coupling and magnetic shielding in the hydrogen-bonding regions of a DNA triplex. J Am Chem Soc. 2001 May 02; 123(17):4014-22. PMID: 11457152.
      View in: PubMed
    69. Feigon J, Butcher SE, Finger LD, Hud NV. Solution nuclear magnetic resonance probing of cation binding sites on nucleic acids. Methods Enzymol. 2001; 338:400-20. PMID: 11460560.
      View in: PubMed
    70. Ravindranathan S, Butcher SE, Feigon J. Adenine protonation in domain B of the hairpin ribozyme. Biochemistry. 2000 Dec 26; 39(51):16026-32. PMID: 11123930.
      View in: PubMed
    71. Allain FH, Bouvet P, Dieckmann T, Feigon J. Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin. EMBO J. 2000 Dec 15; 19(24):6870-81. PMID: 11118222; PMCID: PMC305906.
    72. Withers-Ward ES, Mueller TD, Chen IS, Feigon J. Biochemical and structural analysis of the interaction between the UBA(2) domain of the DNA repair protein HHR23A and HIV-1 Vpr. Biochemistry. 2000 Nov 21; 39(46):14103-12. PMID: 11087358.
      View in: PubMed
    73. Allain FH, Gilbert DE, Bouvet P, Feigon J. Solution structure of the two N-terminal RNA-binding domains of nucleolin and NMR study of the interaction with its RNA target. J Mol Biol. 2000 Oct 20; 303(2):227-41. PMID: 11023788.
      View in: PubMed
    74. Dingley AJ, Masse JE, Feigon J, Grzesiek S. Characterization of the hydrogen bond network in guanosine quartets by internucleotide 3hJ(NC)' and 2hJ(NN) scalar couplings. J Biomol NMR. 2000 Apr; 16(4):279-89. PMID: 10826880.
      View in: PubMed
    75. Butcher SE, Allain FH, Feigon J. Determination of metal ion binding sites within the hairpin ribozyme domains by NMR. Biochemistry. 2000 Mar 07; 39(9):2174-82. PMID: 10694382.
      View in: PubMed
    76. Schultze P, Hud NV, Smith FW, Feigon J. The effect of sodium, potassium and ammonium ions on the conformation of the dimeric quadruplex formed by the Oxytricha nova telomere repeat oligonucleotide d(G(4)T(4)G(4)). Nucleic Acids Res. 1999 Aug 01; 27(15):3018-28. PMID: 10454595; PMCID: PMC148525.
    77. Gilbert DE, Feigon J. Multistranded DNA structures. Curr Opin Struct Biol. 1999 Jun; 9(3):305-14. PMID: 10361092.
      View in: PubMed
    78. Allain FH, Yen YM, Masse JE, Schultze P, Dieckmann T, Johnson RC, Feigon J. Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding. EMBO J. 1999 May 04; 18(9):2563-79. PMID: 10228169; PMCID: PMC1171337.
    79. Sklenár V, Masse JE, Feigon J. HCCCH experiment for through-bond correlation of thymine resonances in 13C-labeled DNA oligonucleotides. J Magn Reson. 1999 Apr; 137(2):345-9. PMID: 10089168.
      View in: PubMed
    80. Butcher SE, Allain FH, Feigon J. Solution structure of the loop B domain from the hairpin ribozyme. Nat Struct Biol. 1999 Mar; 6(3):212-6. PMID: 10074938.
      View in: PubMed
    81. Hud NV, Sklenár V, Feigon J. Localization of ammonium ions in the minor groove of DNA duplexes in solution and the origin of DNA A-tract bending. J Mol Biol. 1999 Feb 26; 286(3):651-60. PMID: 10024440.
      View in: PubMed
    82. Hud NV, Schultze P, Sklenár V, Feigon J. Binding sites and dynamics of ammonium ions in a telomere repeat DNA quadruplex. J Mol Biol. 1999 Jan 08; 285(1):233-43. PMID: 9878402.
      View in: PubMed
    83. Dieckmann T, Withers-Ward ES, Jarosinski MA, Liu CF, Chen IS, Feigon J. Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr. Nat Struct Biol. 1998 Dec; 5(12):1042-7. PMID: 9846873.
      View in: PubMed
    84. Masse JE, Bortmann P, Dieckmann T, Feigon J. Simple, efficient protocol for enzymatic synthesis of uniformly 13C, 15N-labeled DNA for heteronuclear NMR studies. Nucleic Acids Res. 1998 Jun 01; 26(11):2618-24. PMID: 9592146; PMCID: PMC147604.
    85. Tarköy M, Phipps AK, Schultze P, Feigon J. Solution structure of an intramolecular DNA triplex linked by hexakis(ethylene glycol) units: d(AGAGAGAA-(EG)6-TTCTCTCT-(EG)6-TCTCTCTT). Biochemistry. 1998 Apr 28; 37(17):5810-9. PMID: 9558314.
      View in: PubMed
    86. Phipps AK, Tarköy M, Schultze P, Feigon J. Solution structure of an intramolecular DNA triplex containing 5-(1-propynyl)-2'-deoxyuridine residues in the third strand. Biochemistry. 1998 Apr 28; 37(17):5820-30. PMID: 9558315.
      View in: PubMed
    87. Sklenár V, Dieckmann T, Butcher SE, Feigon J. Optimization of triple-resonance HCN experiments for application to larger RNA oligonucleotides. J Magn Reson. 1998 Jan; 130(1):119-24. PMID: 9469906.
      View in: PubMed
    88. Butcher SE, Dieckmann T, Feigon J. Solution structure of a GAAA tetraloop receptor RNA. EMBO J. 1997 Dec 15; 16(24):7490-9. PMID: 9405377; PMCID: PMC1170348.
    89. Dieckmann T, Butcher SE, Sassanfar M, Szostak JW, Feigon J. Mutant ATP-binding RNA aptamers reveal the structural basis for ligand binding. J Mol Biol. 1997 Oct 24; 273(2):467-78. PMID: 9344753.
      View in: PubMed
    90. Uhlenbeck OC, Pardi A, Feigon J. RNA structure comes of age. Cell. 1997 Sep 05; 90(5):833-40. PMID: 9298895.
      View in: PubMed
    91. Butcher SE, Dieckmann T, Feigon J. Solution structure of the conserved 16 S-like ribosomal RNA UGAA tetraloop. J Mol Biol. 1997 May 02; 268(2):348-58. PMID: 9159475.
      View in: PubMed
    92. Dieckmann T, Feigon J. Assignment methodology for larger RNA oligonucleotides: application to an ATP-binding RNA aptamer. J Biomol NMR. 1997 Apr; 9(3):259-72. PMID: 9204555.
      View in: PubMed
    93. Koshlap KM, Schultze P, Brunar H, Dervan PB, Feigon J. Solution structure of an intramolecular DNA triplex containing an N7-glycosylated guanine which mimics a protonated cytosine. Biochemistry. 1997 Mar 04; 36(9):2659-68. PMID: 9054573.
      View in: PubMed
    94. Peterson RD, Feigon J. Structural change in Rev responsive element RNA of HIV-1 on binding Rev peptide. J Mol Biol. 1996 Dec 20; 264(5):863-77. PMID: 9000617.
      View in: PubMed
    95. Hud NV, Smith FW, Anet FA, Feigon J. The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR. Biochemistry. 1996 Dec 03; 35(48):15383-90. PMID: 8952490.
      View in: PubMed
    96. Feigon J, Dieckmann T, Smith FW. Aptamer structures from A to zeta. Chem Biol. 1996 Aug; 3(8):611-7. PMID: 8807893.
      View in: PubMed
    97. Fahrner RL, Dieckmann T, Harwig SS, Lehrer RI, Eisenberg D, Feigon J. Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes. Chem Biol. 1996 Jul; 3(7):543-50. PMID: 8807886.
      View in: PubMed
    98. Dieckmann T, Suzuki E, Nakamura GK, Feigon J. Solution structure of an ATP-binding RNA aptamer reveals a novel fold. RNA. 1996 Jul; 2(7):628-40. PMID: 8756406; PMCID: PMC1369402.
    99. Wang E, Koshlap KM, Gillespie P, Dervan PB, Feigon J. Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3. J Mol Biol. 1996 Apr 19; 257(5):1052-69. PMID: 8632468.
      View in: PubMed
    100. Kelly JA, Feigon J, Yeates TO. Reconciliation of the X-ray and NMR structures of the thrombin-binding aptamer d(GGTTGGTGTGGTTGG). J Mol Biol. 1996 Mar 01; 256(3):417-22. PMID: 8604127.
      View in: PubMed
    101. Sklenár V, Dieckmann T, Butcher SE, Feigon J. Through-bond correlation of imino and aromatic resonances in 13C-, 15N-labeled RNA via heteronuclear TOCSY. J Biomol NMR. 1996 Jan; 7(1):83-7. PMID: 8720835.
      View in: PubMed
    102. Smith FW, Schultze P, Feigon J. Solution structures of unimolecular quadruplexes formed by oligonucleotides containing Oxytricha telomere repeats. Structure. 1995 Oct 15; 3(10):997-1008. PMID: 8590010.
      View in: PubMed
    103. Schneider DJ, Feigon J, Hostomsky Z, Gold L. High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus. Biochemistry. 1995 Jul 25; 34(29):9599-610. PMID: 7542922.
      View in: PubMed
    104. Feigon J, Koshlap KM, Smith FW. 1H NMR spectroscopy of DNA triplexes and quadruplexes. Methods Enzymol. 1995; 261:225-55. PMID: 8569497.
      View in: PubMed
    105. Addess KJ, Feigon J. NMR investigation of Hoogsteen base pairing in quinoxaline antibiotic--DNA complexes: comparison of 2:1 echinomycin, triostin A and [N-MeCys3,N-MeCys7] TANDEM complexes with DNA oligonucleotides. Nucleic Acids Res. 1994 Dec 11; 22(24):5484-91. PMID: 7816641; PMCID: PMC332104.
    106. Smith FW, Lau FW, Feigon J. d(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformations. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10546-50. PMID: 7937991; PMCID: PMC45058.
    107. Addess KJ, Feigon J. Sequence specificity of quinoxaline antibiotics. 2. NMR studies of the binding of [N-MeCys3,N-MeCys7]TANDEM and triostin A to DNA containing a CpI step. Biochemistry. 1994 Oct 18; 33(41):12397-404. PMID: 7918462.
      View in: PubMed
    108. Addess KJ, Feigon J. Sequence specificity of quinoxaline antibiotics. 1. Solution structure of a 1:1 complex between triostin A and [d(GACGTC)]2 and comparison with the solution structure of the [N-MeCys3,N-MeCys7]TANDEM-[d(GATATC)]2 complex. Biochemistry. 1994 Oct 18; 33(41):12386-96. PMID: 7918461.
      View in: PubMed
    109. Peterson RD, Bartel DP, Szostak JW, Horvath SJ, Feigon J. 1H NMR studies of the high-affinity Rev binding site of the Rev responsive element of HIV-1 mRNA: base pairing in the core binding element. Biochemistry. 1994 May 10; 33(18):5357-66. PMID: 8180157.
      View in: PubMed
    110. Schultze P, Smith FW, Feigon J. Refined solution structure of the dimeric quadruplex formed from the Oxytricha telomeric oligonucleotide d(GGGGTTTTGGGG). Structure. 1994 Mar 15; 2(3):221-33. PMID: 8069635.
      View in: PubMed
    111. Schultze P, Macaya RF, Feigon J. Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG). J Mol Biol. 1994 Feb 04; 235(5):1532-47. PMID: 8107090.
      View in: PubMed
    112. Sklenár V, Peterson RD, Rejante MR, Feigon J. Correlation of nucleotide base and sugar protons in a 15N-labeled HIV-1 RNA oligonucleotide by 1H-15N HSQC experiments. J Biomol NMR. 1994 Jan; 4(1):117-22. PMID: 8130637.
      View in: PubMed
    113. Sklenár V, Peterson RD, Rejante MR, Feigon J. Two- and three-dimensional HCN experiments for correlating base and sugar resonances in 15N,13C-labeled RNA oligonucleotides. J Biomol NMR. 1993 Nov; 3(6):721-7. PMID: 7509218.
      View in: PubMed
    114. Feigon J. A new DNA quadruplex. Curr Biol. 1993 Sep 01; 3(9):611-3. PMID: 15335679.
      View in: PubMed
    115. Smith FW, Feigon J. Strand orientation in the DNA quadruplex formed from the Oxytricha telomere repeat oligonucleotide d(G4T4G4) in solution. Biochemistry. 1993 Aug 24; 32(33):8682-92. PMID: 8357810.
      View in: PubMed
    116. Macaya RF, Schultze P, Smith FW, Roe JA, Feigon J. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3745-9. PMID: 8475124; PMCID: PMC46378.
    117. Addess KJ, Sinsheimer JS, Feigon J. Solution structure of a complex between [N-MeCys3,N-MeCys7]TANDEM and [d(GATATC)]2. Biochemistry. 1993 Mar 16; 32(10):2498-508. PMID: 8448108.
      View in: PubMed
    118. Macaya R, Wang E, Schultze P, Sklenár V, Feigon J. Proton nuclear magnetic resonance assignments and structural characterization of an intramolecular DNA triplex. J Mol Biol. 1992 Jun 05; 225(3):755-73. PMID: 1318385.
      View in: PubMed
    119. Wang E, Malek S, Feigon J. Structure of a G.T.A triplet in an intramolecular DNA triplex. Biochemistry. 1992 May 26; 31(20):4838-46. PMID: 1591244.
      View in: PubMed
    120. Gilbert DE, Feigon J. Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites. Nucleic Acids Res. 1992 May 25; 20(10):2411-20. PMID: 1598199; PMCID: PMC312372.
    121. Smith FW, Feigon J. Quadruplex structure of Oxytricha telomeric DNA oligonucleotides. Nature. 1992 Mar 12; 356(6365):164-8. PMID: 1545871.
      View in: PubMed
    122. Addess KJ, Gilbert DE, Olsen RK, Feigon J. Proton NMR studies of [N-MeCys3,N-MeCys7]TANDEM binding to DNA oligonucleotides: sequence-specific binding at the TpA site. Biochemistry. 1992 Jan 21; 31(2):339-50. PMID: 1731892.
      View in: PubMed
    123. Feigon J, Sklenár V, Wang E, Gilbert DE, Macaya RF, Schultze P. 1H NMR spectroscopy of DNA. Methods Enzymol. 1992; 211:235-53. PMID: 1328824.
      View in: PubMed
    124. Macaya RF, Gilbert DE, Malek S, Sinsheimer JS, Feigon J. Structure and stability of X.G.C mismatches in the third strand of intramolecular triplexes. Science. 1991 Oct 11; 254(5029):270-4. PMID: 1925581.
      View in: PubMed
    125. Gilbert DE, Feigon J. The DNA sequence at echinomycin binding sites determines the structural changes induced by drug binding: NMR studies of echinomycin binding to [d(ACGTACGT)]2 and [d(TCGATCGA)]2. Biochemistry. 1991 Mar 05; 30(9):2483-94. PMID: 2001374.
      View in: PubMed
    126. Sklenár V, Feigon J. Formation of a stable triplex from a single DNA strand. Nature. 1990 Jun 28; 345(6278):836-8. PMID: 2359461.
      View in: PubMed
    127. Hua N, van der Marel GA, van Boom JH, Feigon J. Non-contiguous regions of Z-DNA in a DNA dodecamer. Nucleic Acids Res. 1989 Oct 11; 17(19):7923-44. PMID: 2798135; PMCID: PMC334897.
    128. Rajagopal P, Feigon J. NMR studies of triple-strand formation from the homopurine-homopyrimidine deoxyribonucleotides d(GA)4 and d(TC)4. Biochemistry. 1989 Sep 19; 28(19):7859-70. PMID: 2611217.
      View in: PubMed
    129. Rajagopal P, Feigon J. Triple-strand formation in the homopurine:homopyrimidine DNA oligonucleotides d(G-A)4 and d(T-C)4. Nature. 1989 Jun 22; 339(6226):637-40. PMID: 2733796.
      View in: PubMed
    130. Gilbert DE, van der Marel GA, van Boom JH, Feigon J. Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex. Proc Natl Acad Sci U S A. 1989 May; 86(9):3006-10. PMID: 2717609; PMCID: PMC287053.
    131. Ellison MJ, Feigon J, Kelleher RJ, Wang AH, Habener JF, Rich A. An assessment of the Z-DNA forming potential of alternating dA-dT stretches in supercoiled plasmids. Biochemistry. 1986 Jun 17; 25(12):3648-55. PMID: 3718951.
      View in: PubMed
    132. Feigon J, Wang AH, van der Marel GA, Van Boom JH, Rich A. A one- and two-dimensional NMR study of the B to Z transition of (m5dC-dG)3 in methanolic solution. Nucleic Acids Res. 1984 Jan 25; 12(2):1243-63. PMID: 6694910; PMCID: PMC318570.
    133. Feigon J, Denny WA, Leupin W, Kearns DR. Proton nuclear magnetic resonance investigation of the conformation and dynamics in the synthetic deoxyribonucleic acid decamers d(ATATCGATAT) and d(ATATGCATAT). Biochemistry. 1983 Dec 06; 22(25):5930-42. PMID: 6661417.
      View in: PubMed
    134. Feigon J, Leupin W, Denny WA, Kearns DR. Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2. Biochemistry. 1983 Dec 06; 22(25):5943-51. PMID: 6661418.
      View in: PubMed
    135. Feigon J, Wright JM, Denny WA, Leupin W, Kearns DR. Application of multiple-pulse H-NMR techniques to the study of two synthetic DNA decamers. Cold Spring Harb Symp Quant Biol. 1983; 47 Pt 1:207-17. PMID: 6574841.
      View in: PubMed
    136. Feigon J, Leupin W, Denny WA, Kearns DR. Binding of ethidium derivatives to natural DNA: a 300 MHz 1H NMR study. Nucleic Acids Res. 1982 Jan 22; 10(2):749-62. PMID: 7063414; PMCID: PMC326183.
    137. Granot J, Feigon J, Kearns DR. Interactions of DNA with divalent metal ions. I. 31P-NMR studies. Biopolymers. 1982 Jan; 21(1):181-201. PMID: 7055631.
      View in: PubMed
    138. Feigon J, Kearns DR. 1H NMR investigation of the conformational states of DNA in nucleosome core particles. Nucleic Acids Res. 1979; 6(6):2327-37. PMID: 461191; PMCID: PMC327853.
    Juli's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _