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Whitelegge Julian

TitleAdjunct Professor
InstitutionUniversity of California Los Angeles
DepartmentPsychiatry and Biobehavioral Sciences
AddressDepartment of Psychiatry and Biobehavioral Sciences
760 Westwood Plaza
Room 68-146
Los Angeles CA 90095
Phone(310) 794-5156
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    Collapse Research 
    Collapse Research Activities and Funding
    Microfluidics for High-Throughput HDX-MS
    NIH/NIGMS R21GM104593Aug 20, 2012 - May 31, 2015
    Role: Principal Investigator
    Organ-specific NRF2-mediated protein signatures of radiation exposure & tissue da
    NIH/NIAID R01AI101888May 15, 2012 - Apr 30, 2017
    Role: Principal Investigator
    Peptide Biomarkers of drug exposure: from brain microdialysate to plasma
    NIH/NIDA R21DA027499Sep 1, 2009 - Aug 31, 2012
    Role: Co-Principal Investigator
    Proteomic Approaches to Protein Fatty Acylation
    NIH/NCRR R21RR023132Aug 15, 2009 - Jul 31, 2012
    Role: Principal Investigator
    Subtle Modification of Isotope Ratio Proteomics (SMIRP)
    NIH/NCRR R21RR021913Mar 22, 2008 - Feb 28, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Khachatoorian R, Cohn W, Buzzanco A, Riahi R, Arumugaswami V, Dasgupta A, Whitelegge J, French SW. HSP70 Copurifies with Zika Virus Particles. Virology. 2018 Jul 24; 522:228-233. PMID: 30053656.
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    2. Whitelegge J. Lipid Modulation of Membrane Protein Function. Cell Chem Biol. 2018 Jul 19; 25(7):803-804. PMID: 30028973.
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    3. Saelices L, Chung K, Lee JH, Cohn W, Whitelegge J, Benson MD, Eisenberg DS. Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition. Proc Natl Acad Sci U S A. 2018 Jun 28. PMID: 29954863.
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    4. Bömer M, O'Brien JA, Pérez-Salamó I, Krasauskas J, Finch P, Briones A, Daudi A, Souda P, Tsui TL, Whitelegge J, Paul Bolwell G, Devoto A. COI1-dependent jasmonate signalling affects growth, metabolite production and cell wall protein composition in arabidopsis. Ann Bot. 2018 Jun 19. PMID: 29924303.
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    5. Agarwal R, Whitelegge J, Saini S, Shrivastav AP. The S-layer biogenesis system of Synechocystis 6803: Role of Sll1180 and Sll1181 (E. coli HlyB and HlyD analogs) as type-I secretion components for Sll1951 export. Biochim Biophys Acta. 2018 Jul; 1860(7):1436-1446. PMID: 29678468.
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    6. Sallam T, Jones M, Thomas BJ, Wu X, Gilliland T, Qian K, Eskin A, Casero D, Zhang Z, Sandhu J, Salisbury D, Rajbhandari P, Civelek M, Hong C, Ito A, Liu X, Daniel B, Lusis AJ, Whitelegge J, Nagy L, Castrillo A, Smale S, Tontonoz P. Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA. Nat Med. 2018 Mar; 24(3):304-312. PMID: 29431742.
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    7. Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge J, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A. Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. Cell Mol Gastroenterol Hepatol. 2018; 5(4):479-497. PMID: 29930975.
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    8. Maggi M, Mittelman SD, Parmentier JH, Colombo G, Meli M, Whitmire JM, Merrell DS, Whitelegge J, Scotti C. A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep. 2017 Nov 03; 7(1):14479. PMID: 29101342.
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    9. Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z, Gukovsky I, Gukovskaya AS. Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models. Gastroenterology. 2018 02; 154(3):689-703. PMID: 29074451.
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    10. Rao NM, Capri J, Cohn W, Abdaljaleel M, Restrepo L, Gornbein JA, Yong WH, Liebeskind DS, Whitelegge J. Peptide Composition of Stroke Causing Emboli Correlate with Serum Markers of Atherosclerosis and Inflammation. Front Neurol. 2017; 8:427. PMID: 28919876.
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    11. Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, Herschman HR, Whitelegge J, Faull KF, Donahue TR, Czernin J, Radu CG. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nat Commun. 2017 08 14; 8(1):241. PMID: 28808226.
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    12. Kar UK, Simonian M, Whitelegge J. Integral membrane proteins: bottom-up, top-down and structural proteomics. Expert Rev Proteomics. 2017 08; 14(8):715-723. PMID: 28737967.
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    13. Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge J, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. PLoS One. 2017; 12(7):e0181577. PMID: 28732024.
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    14. Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge J, Coppola G, Khakh BS. Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence. Neuron. 2017 Aug 02; 95(3):531-549.e9. PMID: 28712653.
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    15. Budelier MM, Cheng WWL, Bergdoll L, Chen ZW, Janetka JW, Abramson J, Krishnan K, Mydock-McGrane L, Covey DF, Whitelegge J, Evers AS. Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1. J Biol Chem. 2017 06 02; 292(22):9294-9304. PMID: 28396346.
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    16. Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, Villanueva CJ, Lee SD, Nielsen R, Mandrup S, Reue K, Young SG, Whitelegge J, Saez E, Black DL, Tontonoz P. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017 Mar 01; 127(3):987-1004. PMID: 28192372.
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    17. Sarafian TA, Littlejohn K, Yuan S, Fernandez C, Cilluffo M, Koo BK, Whitelegge J, Watson JB. Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated a-synuclein. J Neurosci Res. 2017 Sep; 95(9):1871-1887. PMID: 28117497.
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    18. Capri J, Whitelegge J. Full Membrane Protein Coverage Digestion and Quantitative Bottom-Up Mass Spectrometry Proteomics. Methods Mol Biol. 2017; 1550:61-67. PMID: 28188523.
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    19. Ayers JI, McMahon B, Gill S, Lelie HL, Fromholt S, Brown H, Valentine JS, Whitelegge J, Borchelt DR. Relationship between mutant Cu/Zn superoxide dismutase 1 maturation and inclusion formation in cell models. J Neurochem. 2017 Jan; 140(1):140-150. PMID: 27727458.
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    20. Singh SK, Hasan SS, Zakharov SD, Naurin S, Cohn W, Ma J, Whitelegge J, Cramer WA. Trans-membrane Signaling in Photosynthetic State Transitions: REDOX- AND STRUCTURE-DEPENDENT INTERACTION IN VITRO BETWEEN STT7 KINASE AND THE CYTOCHROME b6f COMPLEX. J Biol Chem. 2016 Oct 07; 291(41):21740-21750. PMID: 27539852.
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    21. Sallam T, Jones MC, Gilliland T, Zhang L, Wu X, Eskin A, Sandhu J, Casero D, Vallim TQ, Hong C, Katz M, Lee R, Whitelegge J, Tontonoz P. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis. Nature. 2016 06 02; 534(7605):124-8. PMID: 27251289; PMCID: PMC4896091 [Available on 11/11/16].
    22. Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge J, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor a is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci Transl Med. 2016 Apr 13; 8(334):334ra54. PMID: 27075628.
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    23. Marcus EA, Tokhtaeva E, Turdikulova S, Capri J, Whitelegge J, Scott DR, Sachs G, Berditchevski F, Vagin O. Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells. Biochem J. 2016 06 15; 473(12):1703-18. PMID: 27048593; PMCID: PMC4903893 [Available on 06/15/17].
    24. Rajkovic A, Hummels KR, Witzky A, Erickson S, Gafken PR, Whitelegge J, Faull KF, Kearns DB, Ibba M. Translation Control of Swarming Proficiency in Bacillus subtilis by 5-Amino-pentanolylated Elongation Factor P. J Biol Chem. 2016 May 20; 291(21):10976-85. PMID: 27002156; PMCID: PMC4900249 [Available on 05/20/17].
    25. Cheung K, Senese S, Kuang J, Bui N, Ongpipattanakul C, Gholkar A, Cohn W, Capri J, Whitelegge J, Torres JZ. Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing. Mol Cell Proteomics. 2016 05; 15(5):1658-69. PMID: 26929214; PMCID: PMC4858946 [Available on 05/01/17].
    26. Barkhoudarian G, Whitelegge J, Kelly DF, Simonian M. Proteomics Analysis of Brain Meningiomas in Pursuit of Novel Biomarkers of the Aggressive Behavior. J Proteomics Bioinform. 2016; 9(2):53-57. PMID: 27019568.
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    27. Lu NT, Liu NM, Vu JQ, Patel D, Cohn W, Capri J, Ziegler M, Patel N, Tramontano A, Williams R, Whitelegge J, French SW. Phospho-Network Analysis Identifies and Quantifies Hepatitis C Virus (HCV)-induced Hepatocellular Carcinoma (HCC) Proteins Regulating Viral-mediated Tumor Growth. Cancer Genomics Proteomics. 2016 09-10; 13(5):339-57. PMID: 27566653.
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    28. Gholkar AA, Senese S, Lo YC, Vides E, Contreras E, Hodara E, Capri J, Whitelegge J, Torres JZ. The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division. Cell Rep. 2016 Jan 12; 14(2):180-8. PMID: 26748699; PMCID: PMC4724641.
    29. Yin JX, Maalouf M, Han P, Zhao M, Gao M, Dharshaun T, Ryan C, Whitelegge J, Wu J, Eisenberg D, Reiman EM, Schweizer FE, Shi J. Ketones block amyloid entry and improve cognition in an Alzheimer's model. Neurobiol Aging. 2016 Mar; 39:25-37. PMID: 26923399.
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    30. Chattopadhyay M, Nwadibia E, Strong CD, Gralla EB, Valentine JS, Whitelegge J. The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation. J Biol Chem. 2015 Dec 18; 290(51):30624-36. PMID: 26511321; PMCID: PMC4683282 [Available on 12/18/16].
    31. Saelices L, Johnson LM, Liang WY, Sawaya MR, Cascio D, Ruchala P, Whitelegge J, Jiang L, Riek R, Eisenberg DS. Uncovering the Mechanism of Aggregation of Human Transthyretin. J Biol Chem. 2015 Nov 27; 290(48):28932-43. PMID: 26459562; PMCID: PMC4661406.
    32. Dada LA, Trejo Bittar HE, Welch LC, Vagin O, Deiss-Yehiely N, Kelly AM, Baker MR, Capri J, Cohn W, Whitelegge J, Vadász I, Gruenbaum Y, Sznajder JI. High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation. Mol Cell Biol. 2015 Dec; 35(23):3962-73. PMID: 26370512; PMCID: PMC4628060.
    33. Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M, Jiang L, Arbing MA, Nannenga BL, Hattne J, Whitelegge J, Brewster AS, Messerschmidt M, Boutet S, Sauter NK, Gonen T, Eisenberg DS. Structure of the toxic core of a-synuclein from invisible crystals. Nature. 2015 Sep 24; 525(7570):486-90. PMID: 26352473; PMCID: PMC4791177.
    34. Micewicz ED, Ratikan JA, Waring AJ, Whitelegge J, McBride WH, Ruchala P. Lipid-conjugated Smac analogues. Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4419-27. PMID: 26384289; PMCID: PMC4592835 [Available on 10/15/16].
    35. Chim N, Torres R, Liu Y, Capri J, Batot G, Whitelegge J, Goulding CW. The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chem Biol. 2015 Aug 20; 22(8):1098-107. PMID: 26278184; PMCID: PMC4546533.
    36. Micewicz ED, Bahattab OS, Willars GB, Waring AJ, Navab M, Whitelegge J, McBride WH, Ruchala P. Small lipidated anti-obesity compounds derived from neuromedin U. Eur J Med Chem. 2015 Aug 28; 101:616-26. PMID: 26204509; PMCID: PMC4543588.
    37. Tanphaichitr N, Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, Souda P, Angel JB, Faull KF, Aitken RJ, Whitelegge J, Hardy D, Berger T, Baker M. Remodeling of the plasma membrane in preparation for sperm-egg recognition: roles of acrosomal proteins. Asian J Androl. 2015 Jul-Aug; 17(4):574-82. PMID: 25994642; PMCID: PMC4492047.
    38. Rajkovic A, Erickson S, Witzky A, Branson OE, Seo J, Gafken PR, Frietas MA, Whitelegge J, Faull KF, Navarre W, Darwin AJ, Ibba M. Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa. MBio. 2015 Jun 09; 6(3):e00823. PMID: 26060278; PMCID: PMC4471567.
    39. Agarwal R, Hasan SS, Jones LM, Stofleth JT, Ryan CM, Whitelegge J, Kehoe DM, Cramer WA. Role of domain swapping in the hetero-oligomeric cytochrome b6f lipoprotein complex. Biochemistry. 2015 May 26; 54(20):3151-63. PMID: 25928281; PMCID: PMC4672631.
    40. Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, Souda P, Angel JB, Faull KF, Aitken RJ, Whitelegge J, Hardy D, Berger T, Baker MA, Tanphaichitr N. Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Reveals Roles of Acrosomal Proteins in ZP3 Binding. J Cell Physiol. 2015 Feb; 230(2):449-63. PMID: 25078272.
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    41. Tokhtaeva E, Capri J, Marcus EA, Whitelegge J, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O. Septin dynamics are essential for exocytosis. J Biol Chem. 2015 Feb 27; 290(9):5280-97. PMID: 25575596; PMCID: PMC4342448.
    42. Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge J, Jackson PK, Torres JZ. Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. Cell Cycle. 2015; 14(7):1116-25. PMID: 25830415; PMCID: PMC4614626.
    43. Deng X, Kohanfars M, Hsu HM, Souda P, Capri J, Whitelegge J, Chang HR. Combined phosphoproteomics and bioinformatics strategy in deciphering drug resistant related pathways in triple negative breast cancer. Int J Proteomics. 2014; 2014:390781. PMID: 25478227; PMCID: PMC4247952.
    44. Veena MS, Wilken R, Zheng JY, Gholkar A, Venkatesan N, Vira D, Ahmed S, Basak SK, Dalgard CL, Ravichandran S, Batra RK, Kasahara N, Elashoff D, Fishbein MC, Whitelegge J, Torres JZ, Wang MB, Srivatsan ES. p16 Protein and gigaxonin are associated with the ubiquitination of NF?B in cisplatin-induced senescence of cancer cells. J Biol Chem. 2014 Dec 12; 289(50):34921-37. PMID: 25331947; PMCID: PMC4263890.
    45. Agarwal R, Zakharov S, Hasan SS, Ryan CM, Whitelegge J, Cramer WA. Structure-function of cyanobacterial outer-membrane protein, Slr1270: homolog of Escherichia coli drug export/colicin import protein, TolC. FEBS Lett. 2014 Nov 03; 588(21):3793-801. PMID: 25218435; PMCID: PMC4288923.
    46. Brumshtein B, Esswein SR, Landau M, Ryan CM, Whitelegge J, Phillips ML, Cascio D, Sawaya MR, Eisenberg DS. Formation of amyloid fibers by monomeric light chain variable domains. J Biol Chem. 2014 Oct 03; 289(40):27513-25. PMID: 25138218; PMCID: PMC4183792.
    47. Thompson MC, Wheatley NM, Jorda J, Sawaya MR, Gidaniyan SD, Ahmed H, Yang Z, McCarty KN, Whitelegge J, Yeates TO. Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein. J Mol Biol. 2014 Sep 23; 426(19):3287-3304. PMID: 25102080; PMCID: PMC4175982.
    48. Vagin O, Tokhtaeva E, Garay PE, Souda P, Bassilian S, Whitelegge J, Lewis R, Sachs G, Wheeler L, Aoki R, Fernandez-Salas E. Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability. J Cell Sci. 2014 Aug 01; 127(Pt 15):3294-308. PMID: 24928902.
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    49. Whitelegge J. Gas-phase structure of the E. coli OmpA dimer. Structure. 2014 May 06; 22(5):666-7. PMID: 24807077.
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    50. Patananan AN, Capri J, Whitelegge J, Clarke SG. Non-repair pathways for minimizing protein isoaspartyl damage in the yeast Saccharomyces cerevisiae. J Biol Chem. 2014 Jun 13; 289(24):16936-53. PMID: 24764295; PMCID: PMC4059137.
    51. Feng Y, Maity R, Whitelegge J, Hadjikyriacou A, Li Z, Zurita-Lopez C, Al-Hadid Q, Clark AT, Bedford MT, Masson JY, Clarke SG. Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions. J Biol Chem. 2013 Dec 27; 288(52):37010-25. PMID: 24247247; PMCID: PMC3873558.
    52. Ayers J, Lelie H, Workman A, Prudencio M, Brown H, Fromholt S, Valentine J, Whitelegge J, Borchelt D. Distinctive features of the D101N and D101G variants of superoxide dismutase 1; two mutations that produce rapidly progressing motor neuron disease. J Neurochem. 2014 Jan; 128(2):305-14. PMID: 24032979; PMCID: PMC3971632.
    53. Puppione D, Whitelegge J. Proteogenomic Review of the Changes in Primate apoC-I during Evolution. Front Biol (Beijing). 2013 Oct; 8(5):533-548. PMID: 28757862.
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    54. Hinman JD, Rao NM, Yallapragada A, Capri J, Souda P, Whitelegge J, Yong WH, Jahan R, Quinones-Baldrich W, Saver JL. Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli. Front Neurol. 2013; 4:104. PMID: 23908644; PMCID: PMC3725951.
    55. Chan PK, Chattopadhyay M, Sharma S, Souda P, Gralla EB, Borchelt DR, Whitelegge J, Valentine JS. Structural similarity of wild-type and ALS-mutant superoxide dismutase-1 fibrils using limited proteolysis and atomic force microscopy. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):10934-9. PMID: 23781106; PMCID: PMC3704032.
    56. Sarafian TA, Ryan CM, Souda P, Masliah E, Kar UK, Vinters HV, Mathern GW, Faull KF, Whitelegge J, Watson JB. Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human a-synuclein. PLoS One. 2013; 8(5):e63557. PMID: 23667637.
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    57. Whitelegge J. Intact protein mass spectrometry and top-down proteomics. Expert Rev Proteomics. 2013 Apr; 10(2):127-9. PMID: 23573779.
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    58. Yang H, Yung M, Li L, Hoch JA, Ryan CM, Kar UK, Souda P, Whitelegge J, Miller JH. Evidence that YycJ is a novel 5'-3' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair. DNA Repair (Amst). 2013 May 01; 12(5):334-46. PMID: 23491602.
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    59. Whitelegge J. Integral membrane proteins and bilayer proteomics. Anal Chem. 2013 Mar 05; 85(5):2558-68. PMID: 23301778; PMCID: PMC3664232.
    60. Howery AE, Elvington S, Abraham SJ, Choi KH, Dworschak-Simpson S, Phillips S, Ryan CM, Sanford RL, Almqvist J, Tran K, Chew TA, Zachariae U, Andersen OS, Whitelegge J, Matulef K, Du Bois J, Maduke MC. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chem Biol. 2012 Nov 21; 19(11):1460-70. PMID: 23177200; PMCID: PMC3508466.
    61. Nazmi AR, Ozorowski G, Pejic M, Whitelegge J, Gerke V, Luecke H. N-terminal acetylation of annexin A2 is required for S100A10 binding. Biol Chem. 2012 Oct; 393(10):1141-50. PMID: 23091277.
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    62. Ozorowski G, Ryan CM, Whitelegge J, Luecke H. Withaferin A binds covalently to the N-terminal domain of annexin A2. Biol Chem. 2012 Oct; 393(10):1151-63. PMID: 23091278.
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    63. Whelan SA, He J, Lu M, Souda P, Saxton RE, Faull KF, Whitelegge J, Chang HR. Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid. J Proteome Res. 2012 Oct 05; 11(10):5034-45. PMID: 22934887; PMCID: PMC3521600.
    64. Ahuja U, Liu M, Tomida S, Park J, Souda P, Whitelegge J, Li H, Harvill ET, Parkhill J, Miller JF. Phenotypic and genomic analysis of hypervirulent human-associated Bordetella bronchiseptica. BMC Microbiol. 2012 Aug 06; 12:167. PMID: 22863321; PMCID: PMC3462115.
    65. Fluman N, Ryan CM, Whitelegge J, Bibi E. Dissection of mechanistic principles of a secondary multidrug efflux protein. Mol Cell. 2012 Sep 14; 47(5):777-87. PMID: 22841484.
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    66. Halgand F, Zabrouskov V, Bassilian S, Souda P, Loo JA, Faull KF, Wong DT, Whitelegge J. Defining intact protein primary structures from saliva: a step toward the human proteome project. Anal Chem. 2012 May 15; 84(10):4383-95. PMID: 22509742; PMCID: PMC3367462.
    67. Prudencio M, Lelie H, Brown HH, Whitelegge J, Valentine JS, Borchelt DR. A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo. J Neurochem. 2012 May; 121(3):475-85. PMID: 22332887; PMCID: PMC3705958.
    68. Laganowsky A, Liu C, Sawaya MR, Whitelegge J, Park J, Zhao M, Pensalfini A, Soriaga AB, Landau M, Teng PK, Cascio D, Glabe C, Eisenberg D. Atomic view of a toxic amyloid small oligomer. Science. 2012 Mar 09; 335(6073):1228-31. PMID: 22403391; PMCID: PMC3959867.
    69. Puppione DL, Della Donna L, Bassilian S, Souda P, MacDonald MH, Whitelegge J. Mass spectral measurements of the apoHDL in horse (Equus caballus) cerebrospinal fluid. Comp Biochem Physiol Part D Genomics Proteomics. 2012 Jun; 7(2):172-4. PMID: 22377539.
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    70. O'Brien JA, Daudi A, Finch P, Butt VS, Whitelegge J, Souda P, Ausubel FM, Bolwell GP. A peroxidase-dependent apoplastic oxidative burst in cultured Arabidopsis cells functions in MAMP-elicited defense. Plant Physiol. 2012 Apr; 158(4):2013-27. PMID: 22319074; PMCID: PMC3320203.
    71. Ziegler ME, Souda P, Jin YP, Whitelegge J, Reed EF. Characterization of the endothelial cell cytoskeleton following HLA class I ligation. PLoS One. 2012; 7(1):e29472. PMID: 22247778; PMCID: PMC3256144.
    72. Sheng Y, Chattopadhyay M, Whitelegge J, Valentine JS. SOD1 aggregation and ALS: role of metallation states and disulfide status. Curr Top Med Chem. 2012; 12(22):2560-72. PMID: 23339308.
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    73. Hajagos BE, Turetzky JM, Peng ED, Cheng SJ, Ryan CM, Souda P, Whitelegge J, Lebrun M, Dubremetz JF, Bradley PJ. Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1. Traffic. 2012 Feb; 13(2):292-304. PMID: 22035499; PMCID: PMC3375832.
    74. Cramer WA, Zakharov SD, Saif Hasan S, Zhang H, Baniulis D, Zhalnina MV, Soriano GM, Sharma O, Rochet JC, Ryan C, Whitelegge J, Kurisu G, Yamashita E. Membrane proteins in four acts: function precedes structure determination. Methods. 2011 Dec; 55(4):415-20. PMID: 22079407; PMCID: PMC3282554.
    75. He J, Whelan SA, Lu M, Shen D, Chung DU, Saxton RE, Faull KF, Whitelegge J, Chang HR. Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response. Int J Proteomics. 2011; 2011:896476. PMID: 22110952; PMCID: PMC3202144.
    76. Whitelegge J. Structural biology. Up close with membrane lipid-protein complexes. Science. 2011 Oct 21; 334(6054):320-1. PMID: 22021848.
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    77. Nally JE, Monahan AM, Miller IS, Bonilla-Santiago R, Souda P, Whitelegge J. Comparative proteomic analysis of differentially expressed proteins in the urine of reservoir hosts of leptospirosis. PLoS One. 2011; 6(10):e26046. PMID: 22043303; PMCID: PMC3197145.
    78. Della Donna L, Bassilian S, Souda P, Nebbia C, Whitelegge J, Puppione DL. Mass spectrometric measurements of the apolipoproteins of bovine (Bos taurus) HDL. Comp Biochem Physiol Part D Genomics Proteomics. 2012 Mar; 7(1):9-13. PMID: 22056023.
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    79. Souda P, Ryan CM, Cramer WA, Whitelegge J. Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry. Methods. 2011 Dec; 55(4):330-6. PMID: 21982782; PMCID: PMC3498814.
    80. Hasan SS, Yamashita E, Ryan CM, Whitelegge J, Cramer WA. Conservation of lipid functions in cytochrome bc complexes. J Mol Biol. 2011 Nov 18; 414(1):145-62. PMID: 21978667; PMCID: PMC3215850.
    81. Tokhtaeva E, Sachs G, Souda P, Bassilian S, Whitelegge J, Shoshani L, Vagin O. Epithelial junctions depend on intercellular trans-interactions between the Na,K-ATPase ß1 subunits. J Biol Chem. 2011 Jul 22; 286(29):25801-12. PMID: 21642423; PMCID: PMC3138299.
    82. Whitelegge J, Komatsu S, Jorrin-Novo J. Diverse facets of plant proteomics. Phytochemistry. 2011 Jul; 72(10):961-2. PMID: 21543094.
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    83. Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge J, Horwitz MA, Goulding CW. Discovery and characterization of a unique mycobacterial heme acquisition system. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):5051-6. PMID: 21383189; PMCID: PMC3064333.
    84. Nowaczyk MM, Wulfhorst H, Ryan CM, Souda P, Zhang H, Cramer WA, Whitelegge J. NdhP and NdhQ: two novel small subunits of the cyanobacterial NDH-1 complex. Biochemistry. 2011 Feb 22; 50(7):1121-4. PMID: 21244052; PMCID: PMC3040284.
    85. Thangaraj B, Jolley CC, Sarrou I, Bultema JB, Greyslak J, Whitelegge J, Lin S, Kouril R, Subramanyam R, Boekema EJ, Fromme P. Efficient light harvesting in a dark, hot, acidic environment: the structure and function of PSI-LHCI from Galdieria sulphuraria. Biophys J. 2011 Jan 05; 100(1):135-43. PMID: 21190665; PMCID: PMC3010194.
    86. Leuchter AF, Cook IA, Hamilton SP, Narr KL, Toga A, Hunter AM, Faull K, Whitelegge J, Andrews AM, Loo J, Way B, Nelson SF, Horvath S, Lebowitz BD. Biomarkers to predict antidepressant response. Curr Psychiatry Rep. 2010 Dec; 12(6):553-62. PMID: 20963521; PMCID: PMC2965366.
    87. Marques PX, O'Donovan J, Souda P, Gutierrez J, Williams EJ, Worrall S, McElroy M, Proctor A, Brady C, Sammin D, Basset H, Whitelegge J, Markey BK, Nally JE. Amniotic and allantoic fluids from experimentally infected sheep contain immunoglobulin specific for Chlamydophila abortus. Vet Immunol Immunopathol. 2011 Mar 15; 140(1-2):1-9. PMID: 21126774.
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    88. Lelie HL, Liba A, Bourassa MW, Chattopadhyay M, Chan PK, Gralla EB, Miller LM, Borchelt DR, Valentine JS, Whitelegge J. Copper and zinc metallation status of copper-zinc superoxide dismutase from amyotrophic lateral sclerosis transgenic mice. J Biol Chem. 2011 Jan 28; 286(4):2795-806. PMID: 21068388; PMCID: PMC3024775.
    89. de Vries S, Momcilovic M, Strampraad MJ, Whitelegge J, Baghai A, Schröder I. Adaptation to a high-tungsten environment: Pyrobaculum aerophilum contains an active tungsten nitrate reductase. Biochemistry. 2010 Nov 16; 49(45):9911-21. PMID: 20863064.
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    90. Thangaraj B, Ryan CM, Souda P, Krause K, Faull KF, Weber AP, Fromme P, Whitelegge J. Data-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex: photosystem II from Galdieria sulphuraria. Proteomics. 2010 Oct; 10(20):3644-56. PMID: 20845333; PMCID: PMC3517113.
    91. Prudencio M, Durazo A, Whitelegge J, Borchelt DR. An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1. Hum Mol Genet. 2010 Dec 15; 19(24):4774-89. PMID: 20871097; PMCID: PMC2989888.
    92. Webb KJ, Zurita-Lopez CI, Al-Hadid Q, Laganowsky A, Young BD, Lipson RS, Souda P, Faull KF, Whitelegge J, Clarke SG. A novel 3-methylhistidine modification of yeast ribosomal protein Rpl3 is dependent upon the YIL110W methyltransferase. J Biol Chem. 2010 Nov 26; 285(48):37598-606. PMID: 20864530; PMCID: PMC2988365.
    93. Liu X, Inbar Y, Dorrestein PC, Wynne C, Edwards N, Souda P, Whitelegge J, Bafna V, Pevzner PA. Deconvolution and database search of complex tandem mass spectra of intact proteins: a combinatorial approach. Mol Cell Proteomics. 2010 Dec; 9(12):2772-82. PMID: 20855543; PMCID: PMC3101958.
    94. Lu M, Whelan SA, He J, Saxton RE, Faull KF, Whitelegge J, Chang HR. Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer. Clin Proteomics. 2010 Sep; 6(3):93-103. PMID: 20930921.
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    95. Keire DA, Whitelegge J, Souda P, Faull KF, Bassilian S, Reidelberger RD, Haver AC, Reeve JR. PYY(1-36) is the major form of PYY in rat distal small intestine: quantification using high-resolution mass spectrometry. Regul Pept. 2010 Dec 10; 165(2-3):151-7. PMID: 20615437; PMCID: PMC3971906.
    96. Webb KJ, Lipson RS, Al-Hadid Q, Whitelegge J, Clarke SG. Identification of protein N-terminal methyltransferases in yeast and humans. Biochemistry. 2010 Jun 29; 49(25):5225-35. PMID: 20481588; PMCID: PMC2890028.
    97. Marques PX, Souda P, O'Donovan J, Gutierrez J, Gutierrez EJ, Worrall S, McElroy M, Proctor A, Brady C, Sammin D, Basset HF, Whitelegge J, Markey BE, Nally JE. Identification of immunologically relevant proteins of Chlamydophila abortus using sera from experimentally infected pregnant ewes. Clin Vaccine Immunol. 2010 Aug; 17(8):1274-81. PMID: 20554807; PMCID: PMC2916250.
    98. Srikanth S, Jung HJ, Kim KD, Souda P, Whitelegge J, Gwack Y. A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. Nat Cell Biol. 2010 May; 12(5):436-46. PMID: 20418871; PMCID: PMC2875865.
    99. Gundersen CB, Kohan SA, Souda P, Whitelegge J, Umbach JA. Cysteine string protein beta is prominently associated with nerve terminals and secretory organelles in mouse brain. Brain Res. 2010 May 21; 1332:1-11. PMID: 20338151.
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    100. Crofts AJ, Crofts N, Whitelegge J, Okita TW. Isolation and identification of cytoskeleton-associated prolamine mRNA binding proteins from developing rice seeds. Planta. 2010 May; 231(6):1261-76. PMID: 20217123.
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    101. Puppione DL, Ryan CM, Bassilian S, Souda P, Xiao X, Ryder OA, Whitelegge J. Detection of two distinct forms of apoC-I in great apes. Comp Biochem Physiol Part D Genomics Proteomics. 2010 Mar; 5(1):73-9. PMID: 20209111.
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    102. Shoemaker LD, Orozco NM, Geschwind DH, Whitelegge J, Faull KF, Kornblum HI. Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors. PLoS One. 2010 Feb 09; 5(2):e9121. PMID: 20161753; PMCID: PMC2817745.
    103. Ryan CM, Souda P, Halgand F, Wong DT, Loo JA, Faull KF, Whitelegge J. Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry. J Am Soc Mass Spectrom. 2010 Jun; 21(6):908-17. PMID: 20189825; PMCID: PMC2873128.
    104. Halgand F, Zabrouskov V, Bassilian S, Souda P, Wong DT, Loo JA, Faull KF, Whitelegge J. Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry. J Am Soc Mass Spectrom. 2010 May; 21(5):868-77. PMID: 20185333.
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    105. Lu M, Whitelegge J, Whelan SA, He J, Saxton RE, Faull KF, Chang HR. Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer. J Proteomics Bioinform. 2010 Jan 22; 3(2):1-10. PMID: 20596302.
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    106. Ryan CM, Souda P, Bassilian S, Ujwal R, Zhang J, Abramson J, Ping P, Durazo A, Bowie JU, Hasan SS, Baniulis D, Cramer WA, Faull KF, Whitelegge J. Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation. Mol Cell Proteomics. 2010 May; 9(5):791-803. PMID: 20093275; PMCID: PMC2871414.
    107. Chim N, Riley R, The J, Im S, Segelke B, Lekin T, Yu M, Hung LW, Terwilliger T, Whitelegge J, Goulding CW. An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. J Mol Biol. 2010 Mar 12; 396(5):1211-26. PMID: 20060836; PMCID: PMC2883863.
    108. Shaw BF, Moustakas DT, Whitelegge J, Faull KF. Taking charge of proteins from neurodegeneration to industrial biotechnology. Adv Protein Chem Struct Biol. 2010; 79:127-64. PMID: 20621283.
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    109. Puppione DL, Donna LD, Laganowsky AD, Bassilian S, Souda P, Ryder OA, Whitelegge J. Mass spectral analyses of the two major apolipoproteins of great ape high density lipoproteins. Comp Biochem Physiol Part D Genomics Proteomics. 2009 Dec; 4(4):305-9. PMID: 21298813.
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    110. Averette KM, Pratt MR, Yang Y, Bassilian S, Whitelegge J, Loo JA, Muir TW, Bradley KA. Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent. PLoS One. 2009 Nov 18; 4(11):e7913. PMID: 19924255; PMCID: PMC2775945.
    111. Budzik JM, Poor CB, Faull KF, Whitelegge J, He C, Schneewind O. Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A. 2009 Nov 24; 106(47):19992-7. PMID: 19903875; PMCID: PMC2785280.
    112. Yuan Q, Kaylor JJ, Miu A, Bassilian S, Whitelegge J, Travis GH. Rpe65 isomerase associates with membranes through an electrostatic interaction with acidic phospholipid headgroups. J Biol Chem. 2010 Jan 08; 285(2):988-99. PMID: 19892706; PMCID: PMC2801300.
    113. Sun S, La Scola B, Bowman VD, Ryan CM, Whitelegge J, Raoult D, Rossmann MG. Structural studies of the Sputnik virophage. J Virol. 2010 Jan; 84(2):894-7. PMID: 19889775; PMCID: PMC2798384.
    114. Durazo A, Shaw BF, Chattopadhyay M, Faull KF, Nersissian AM, Valentine JS, Whitelegge J. Metal-free superoxide dismutase-1 and three different amyotrophic lateral sclerosis variants share a similar partially unfolded beta-barrel at physiological temperature. J Biol Chem. 2009 Dec 04; 284(49):34382-9. PMID: 19805550; PMCID: PMC2797206.
    115. He J, Shen D, Chung DU, Saxton RE, Whitelegge J, Faull KF, Chang HR. Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy. Int J Oncol. 2009 Oct; 35(4):683-92. PMID: 19724903.
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    116. Joh NH, Oberai A, Yang D, Whitelegge J, Bowie JU. Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J Am Chem Soc. 2009 Aug 12; 131(31):10846-7. PMID: 19603754; PMCID: PMC2744480.
    117. Whelan SA, Lu M, He J, Yan W, Saxton RE, Faull KF, Whitelegge J, Chang HR. Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. J Proteome Res. 2009 Aug; 8(8):4151-60. PMID: 19522481; PMCID: PMC2761014.
    118. Millar DJ, Whitelegge J, Bindschedler LV, Rayon C, Boudet AM, Rossignol M, Borderies G, Bolwell GP. The cell wall and secretory proteome of a tobacco cell line synthesising secondary wall. Proteomics. 2009 May; 9(9):2355-72. PMID: 19402043.
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    119. Laganowsky A, Gómez SM, Whitelegge J, Nishio JN. Hydroponics on a chip: analysis of the Fe deficient Arabidopsis thylakoid membrane proteome. J Proteomics. 2009 Apr 13; 72(3):397-415. PMID: 19367733.
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    120. Erales J, Gontero B, Whitelegge J, Halgand F. Mapping of a copper-binding site on the small CP12 chloroplastic protein of Chlamydomonas reinhardtii using top-down mass spectrometry and site-directed mutagenesis. Biochem J. 2009 Apr 01; 419(1):75-82, 4 p following 82. PMID: 19099541.
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    121. Baniulis D, Yamashita E, Whitelegge J, Zatsman AI, Hendrich MP, Hasan SS, Ryan CM, Cramer WA. Structure-Function, Stability, and Chemical Modification of the Cyanobacterial Cytochrome b6f Complex from Nostoc sp. PCC 7120. J Biol Chem. 2009 Apr 10; 284(15):9861-9. PMID: 19189962; PMCID: PMC2665108.
    122. Doolittle MH, Ben-Zeev O, Bassilian S, Whitelegge J, Péterfy M, Wong H. Hepatic lipase maturation: a partial proteome of interacting factors. J Lipid Res. 2009 Jun; 50(6):1173-84. PMID: 19136429; PMCID: PMC2681399.
    123. Prudencio M, Durazo A, Whitelegge J, Borchelt DR. Modulation of mutant superoxide dismutase 1 aggregation by co-expression of wild-type enzyme. J Neurochem. 2009 Feb; 108(4):1009-18. PMID: 19077113; PMCID: PMC2801375.
    124. Chattopadhyay M, Durazo A, Sohn SH, Strong CD, Gralla EB, Whitelegge J, Valentine JS. Initiation and elongation in fibrillation of ALS-linked superoxide dismutase. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18663-8. PMID: 19022905.
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    125. Webb KJ, Laganowsky A, Whitelegge J, Clarke SG. Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab. J Biol Chem. 2008 Dec 19; 283(51):35561-8. PMID: 18957409; PMCID: PMC2602916.
    126. Puppione DL, Bassilian S, Souda P, MacDonald MH, Halgand F, Hagland F, Whitelegge J. Mass spectral analysis of the apolipoproteins on dog (Canis lupus familiaris) high density lipoproteins. Detection of apolipoprotein A-II. Comp Biochem Physiol Part D Genomics Proteomics. 2008 Dec; 3(4):290-6. PMID: 20483223.
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    127. Budzik JM, Marraffini LA, Souda P, Whitelegge J, Faull KF, Schneewind O. Amide bonds assemble pili on the surface of bacilli. Proc Natl Acad Sci U S A. 2008 Jul 22; 105(29):10215-20. PMID: 18621716; PMCID: PMC2481347.
    128. Lu H, Zong C, Wang Y, Young GW, Deng N, Souda P, Li X, Whitelegge J, Drews O, Yang PY, Ping P. Revealing the dynamics of the 20 S proteasome phosphoproteome: a combined CID and electron transfer dissociation approach. Mol Cell Proteomics. 2008 Nov; 7(11):2073-89. PMID: 18579562; PMCID: PMC2577207.
    129. Joh NH, Min A, Faham S, Whitelegge J, Yang D, Woods VL, Bowie JU. Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature. 2008 Jun 26; 453(7199):1266-70. PMID: 18500332; PMCID: PMC2734483.
    130. Shaw BF, Schneider GF, Bilgiçer B, Kaufman GK, Neveu JM, Lane WS, Whitelegge J, Whitesides GM. Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation. Protein Sci. 2008 Aug; 17(8):1446-55. PMID: 18451358; PMCID: PMC2492826.
    131. Keire DA, Whitelegge J, Bassilian S, Faull KF, Wiggins BW, Mehdizadeh OB, Reidelberger RD, Haver AC, Sayegh AI, Reeve JR. A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36). Regul Pept. 2008 Nov 29; 151(1-3):61-70. PMID: 18501442.
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    132. Denny P, Hagen FK, Hardt M, Liao L, Yan W, Arellanno M, Bassilian S, Bedi GS, Boontheung P, Cociorva D, Delahunty CM, Denny T, Dunsmore J, Faull KF, Gilligan J, Gonzalez-Begne M, Halgand F, Hall SC, Han X, Henson B, Hewel J, Hu S, Jeffrey S, Jiang J, Loo JA, Ogorzalek Loo RR, Malamud D, Melvin JE, Miroshnychenko O, Navazesh M, Niles R, Park SK, Prakobphol A, Ramachandran P, Richert M, Robinson S, Sondej M, Souda P, Sullivan MA, Takashima J, Than S, Wang J, Whitelegge J, Witkowska HE, Wolinsky L, Xie Y, Xu T, Yu W, Ytterberg J, Wong DT, Yates JR, Fisher SJ. The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res. 2008 May; 7(5):1994-2006. PMID: 18361515; PMCID: PMC2839126.
    133. Shaw BF, Lelie HL, Durazo A, Nersissian AM, Xu G, Chan PK, Gralla EB, Tiwari A, Hayward LJ, Borchelt DR, Valentine JS, Whitelegge J. Detergent-insoluble aggregates associated with amyotrophic lateral sclerosis in transgenic mice contain primarily full-length, unmodified superoxide dismutase-1. J Biol Chem. 2008 Mar 28; 283(13):8340-50. PMID: 18192269; PMCID: PMC2276386.
    134. Grintsevich EE, Benchaar SA, Warshaviak D, Boontheung P, Halgand F, Whitelegge J, Faull KF, Loo RR, Sept D, Loo JA, Reisler E. Mapping the cofilin binding site on yeast G-actin by chemical cross-linking. J Mol Biol. 2008 Mar 21; 377(2):395-409. PMID: 18258262; PMCID: PMC3052258.
    135. Fujishige NA, Lum MR, De Hoff PL, Whitelegge J, Faull KF, Hirsch AM. Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 2008 Feb; 67(3):504-15. PMID: 18086203.
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    136. Farrokhi N, Whitelegge J, Brusslan JA. Plant peptides and peptidomics. Plant Biotechnol J. 2008 Feb; 6(2):105-34. PMID: 18069950.
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    137. Whitelegge J, Zabrouskov V, Halgand F, Souda P, Bassilian S, Yan W, Wolinsky L, Loo JA, Wong DT, Faull KF. Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry. Int J Mass Spectrom. 2007 Dec 01; 268(2-3):190-197. PMID: 19050733.
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    138. Lu M, Faull KF, Whitelegge J, He J, Shen D, Saxton RE, Chang HR. Proteomics and mass spectrometry for cancer biomarker discovery. Biomark Insights. 2007 Oct 03; 2:347-60. PMID: 19662217; PMCID: PMC2717808.
    139. Nally JE, Whitelegge J, Carroll JA. Proteomic strategies to elucidate pathogenic mechanisms of spirochetes. Proteomics Clin Appl. 2007 Sep; 1(9):1185-97. PMID: 21136767.
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    140. Taylor CF, Paton NW, Lilley KS, Binz PA, Julian RK, Jones AR, Zhu W, Apweiler R, Aebersold R, Deutsch EW, Dunn MJ, Heck AJ, Leitner A, Macht M, Mann M, Martens L, Neubert TA, Patterson SD, Ping P, Seymour SL, Souda P, Tsugita A, Vandekerckhove J, Vondriska TM, Whitelegge J, Wilkins MR, Xenarios I, Yates JR, Hermjakob H. The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol. 2007 Aug; 25(8):887-93. PMID: 17687369.
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    141. Bortz E, Wang L, Jia Q, Wu TT, Whitelegge J, Deng H, Zhou ZH, Sun R. Murine gammaherpesvirus 68 ORF52 encodes a tegument protein required for virion morphogenesis in the cytoplasm. J Virol. 2007 Sep; 81(18):10137-50. PMID: 17634243; PMCID: PMC2045416.
    142. Xie J, Marusich MF, Souda P, Whitelegge J, Capaldi RA. The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11. FEBS Lett. 2007 Jul 24; 581(18):3545-9. PMID: 17624330.
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    143. Banci L, Bertini I, Durazo A, Girotto S, Gralla EB, Martinelli M, Valentine JS, Vieru M, Whitelegge J. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11263-7. PMID: 17592131; PMCID: PMC1899188.
    144. Watanabe J, Chou KJ, Liao JC, Miao Y, Meng HH, Ge H, Grijalva V, Hama S, Kozak K, Buga G, Whitelegge J, Lee TD, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST. Differential association of hemoglobin with proinflammatory high density lipoproteins in atherogenic/hyperlipidemic mice. A novel biomarker of atherosclerosis. J Biol Chem. 2007 Aug 10; 282(32):23698-707. PMID: 17556366.
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    145. Zabrouskov V, Whitelegge J. Increased coverage in the transmembrane domain with activated-ion electron capture dissociation for top-down Fourier-transform mass spectrometry of integral membrane proteins. J Proteome Res. 2007 Jun; 6(6):2205-10. PMID: 17441748.
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    146. Boutz DR, Cascio D, Whitelegge J, Perry LJ, Yeates TO. Discovery of a thermophilic protein complex stabilized by topologically interlinked chains. J Mol Biol. 2007 May 18; 368(5):1332-44. PMID: 17395198; PMCID: PMC1955483.
    147. Waldron RT, Whitelegge J, Faull KF, Rozengurt E. Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D. Biochem Biophys Res Commun. 2007 May 04; 356(2):361-7. PMID: 17359934; PMCID: PMC2765859.
    148. Porras-Yakushi TR, Whitelegge J, Clarke S. Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs. J Biol Chem. 2007 Apr 27; 282(17):12368-76. PMID: 17327221.
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    149. Kawaguchi R, Yu J, Honda J, Hu J, Whitelegge J, Ping P, Wiita P, Bok D, Sun H. A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A. Science. 2007 Feb 09; 315(5813):820-5. PMID: 17255476.
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    150. He J, Gornbein J, Shen D, Lu M, Rovai LE, Shau H, Katz J, Whitelegge J, Faull KF, Chang HR. Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry. Int J Oncol. 2007 Jan; 30(1):145-54. PMID: 17143523.
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    151. Whitelegge J, Halgand F, Souda P, Zabrouskov V. Top-down mass spectrometry of integral membrane proteins. Expert Rev Proteomics. 2006 Dec; 3(6):585-96. PMID: 17181473.
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    152. Nally JE, Whitelegge J, Bassilian S, Blanco DR, Lovett MA. Characterization of the outer membrane proteome of Leptospira interrogans expressed during acute lethal infection. Infect Immun. 2007 Feb; 75(2):766-73. PMID: 17101664; PMCID: PMC1828474.
    153. Porras-Yakushi TR, Whitelegge J, Clarke S. A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10. J Biol Chem. 2006 Nov 24; 281(47):35835-45. PMID: 17005568.
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    154. Ding Q, Vaynman S, Souda P, Whitelegge J, Gomez-Pinilla F. Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis. Eur J Neurosci. 2006 Sep; 24(5):1265-76. PMID: 16987214.
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    155. Puppione DL, Yam LM, Bassilian S, Souda P, Castellani LW, Schumaker VN, Whitelegge J. Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications. Biochim Biophys Acta. 2006 Aug; 1764(8):1363-71. PMID: 16876491.
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    156. Shaw BF, Durazo A, Nersissian AM, Whitelegge J, Faull KF, Valentine JS. Local unfolding in a destabilized, pathogenic variant of superoxide dismutase 1 observed with H/D exchange and mass spectrometry. J Biol Chem. 2006 Jun 30; 281(26):18167-76. PMID: 16644738.
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    157. Whitelegge J, Laganowsky A, Nishio J, Souda P, Zhang H, Cramer WA. Sequencing covalent modifications of membrane proteins. J Exp Bot. 2006; 57(7):1515-22. PMID: 16574746.
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    158. Bindschedler LV, Whitelegge J, Millar DJ, Bolwell GP. A two component chitin-binding protein from French bean -- association of a proline-rich protein with a cysteine-rich polypeptide. FEBS Lett. 2006 Mar 06; 580(6):1541-6. PMID: 16480721.
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    159. Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU. Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site. EMBO J. 2006 Jan 11; 25(1):70-9. PMID: 16362034; PMCID: PMC1356365.
    160. Kozak KR, Su F, Whitelegge J, Faull K, Reddy S, Farias-Eisner R. Characterization of serum biomarkers for detection of early stage ovarian cancer. Proteomics. 2005 Nov; 5(17):4589-96. PMID: 16237736.
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    161. Puppione DL, Whitelegge J, Yam LM, Bassilian S, Schumaker VN, MacDonald MH. Mass spectral analysis of domestic and wild equine apoA-I and A-II: detection of unique dimeric forms of apoA-II. Comp Biochem Physiol B Biochem Mol Biol. 2005 Dec; 142(4):369-73. PMID: 16230041.
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    162. Porras-Yakushi TR, Whitelegge J, Miranda TB, Clarke S. A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. J Biol Chem. 2005 Oct 14; 280(41):34590-8. PMID: 16096273.
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    163. Berhane BT, Zong C, Liem DA, Huang A, Le S, Edmondson RD, Jones RC, Qiao X, Whitelegge J, Ping P, Vondriska TM. Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project pilot phase. Proteomics. 2005 Aug; 5(13):3520-30. PMID: 16052623.
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    164. Norris AJ, Whitelegge J, Yaghoubian A, Alattia JR, Privé GG, Toyokuni T, Sun H, Brooks MN, Panza L, Matto P, Compostella F, Remmel N, Klingenstein R, Sandhoff K, Fluharty C, Fluharty A, Faull KF. A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A. J Lipid Res. 2005 Oct; 46(10):2254-64. PMID: 16061947.
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    165. Kozak NA, Mattoo S, Foreman-Wykert AK, Whitelegge J, Miller JF. Interactions between partner switcher orthologs BtrW and BtrV regulate type III secretion in Bordetella. J Bacteriol. 2005 Aug; 187(16):5665-76. PMID: 16077112; PMCID: PMC1196064.
    166. Lu M, Zhang L, Maul RS, Sartippour MR, Norris A, Whitelegge J, Rao JY, Brooks MN. The novel gene EG-1 stimulates cellular proliferation. Cancer Res. 2005 Jul 15; 65(14):6159-66. PMID: 16024617.
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    167. Gomes AV, Zong C, Edmondson RD, Berhane BT, Wang GW, Le S, Young G, Zhang J, Vondriska TM, Whitelegge J, Jones RC, Joshua IG, Thyparambil S, Pantaleon D, Qiao J, Loo J, Ping P. The murine cardiac 26S proteasome: an organelle awaiting exploration. Ann N Y Acad Sci. 2005 Jun; 1047:197-207. PMID: 16093497.
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    168. Puppione DL, Whitelegge J, Yam LM, Schumaker VN. Mass spectral analysis of pig (Sus scrofa) apo HDL: Identification of pig apoA-II, a dimeric apolipoprotein. Comp Biochem Physiol B Biochem Mol Biol. 2005 May; 141(1):89-94. PMID: 15820138.
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    169. Blanco DR, Champion CI, Dooley A, Cox DL, Whitelegge J, Faull K, Lovett MA. A monoclonal antibody that conveys in vitro killing and partial protection in experimental syphilis binds a phosphorylcholine surface epitope of Treponema pallidum. Infect Immun. 2005 May; 73(5):3083-95. PMID: 15845516; PMCID: PMC1087381.
    170. Whitelegge J. Mass spectrometry for high throughput quantitative proteomics in plant research: lessons from thylakoid membranes. Plant Physiol Biochem. 2004 Dec; 42(12):919-27. PMID: 15707830.
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    171. Liu C, Willmund F, Whitelegge J, Hawat S, Knapp B, Lodha M, Schroda M. J-domain protein CDJ2 and HSP70B are a plastidic chaperone pair that interacts with vesicle-inducing protein in plastids 1. Mol Biol Cell. 2005 Mar; 16(3):1165-77. PMID: 15635096; PMCID: PMC551482.
    172. Nally JE, Whitelegge J, Aguilera R, Pereira MM, Blanco DR, Lovett MA. Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni. Proteomics. 2005 Jan; 5(1):144-52. PMID: 15672460.
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    173. Weinglass AB, Soskine M, Vazquez-Ibar JL, Whitelegge J, Faull KF, Kaback HR, Schuldiner S. Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry. J Biol Chem. 2005 Mar 04; 280(9):7487-92. PMID: 15623511.
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    174. Barwe SP, Anilkumar G, Moon SY, Zheng Y, Whitelegge J, Rajasekaran SA, Rajasekaran AK. Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell. 2005 Mar; 16(3):1082-94. PMID: 15616195; PMCID: PMC551475.
    175. Chun HH, Cary RB, Lansigan F, Whitelegge J, Rawlings DJ, Gatti RA. ATM protein purified from vaccinia virus expression system: DNA binding requirements for kinase activation. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):74-81. PMID: 15313175.
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    176. Crother TR, Champion CI, Whitelegge J, Aguilera R, Wu XY, Blanco DR, Miller JN, Lovett MA. Temporal analysis of the antigenic composition of Borrelia burgdorferi during infection in rabbit skin. Infect Immun. 2004 Sep; 72(9):5063-72. PMID: 15321999; PMCID: PMC517453.
    177. Weinglass AB, Whitelegge J, Kaback HR. Integrating mass spectrometry into membrane protein drug discovery. Curr Opin Drug Discov Devel. 2004 Sep; 7(5):589-99. PMID: 15503862.
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    178. Yohannan S, Yang D, Faham S, Boulting G, Whitelegge J, Bowie JU. Proline substitutions are not easily accommodated in a membrane protein. J Mol Biol. 2004 Jul 30; 341(1):1-6. PMID: 15312757.
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    179. Weinglass A, Whitelegge J, Faull KF, Kaback HR. Monitoring conformational rearrangements in the substrate-binding site of a membrane transport protein by mass spectrometry. J Biol Chem. 2004 Oct 01; 279(40):41858-65. PMID: 15272008.
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    180. Puppione DL, Fischer WH, Park M, Whitelegge J, Schumaker VN, Golfeiz S, MacDonald MH. Sequence of horse (Equus caballus) apoA-II. Another example of a dimer forming apolipoprotein. Comp Biochem Physiol B Biochem Mol Biol. 2004 Jul; 138(3):213-20. PMID: 15253869.
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    181. Whitelegge J, Katz JE, Pihakari KA, Hale R, Aguilera R, Gómez SM, Faull KF, Vavilin D, Vermaas W. Subtle modification of isotope ratio proteomics; an integrated strategy for expression proteomics. Phytochemistry. 2004 Jun; 65(11):1507-15. PMID: 15276448.
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    182. Tu X, Huang A, Bae D, Slaughter N, Whitelegge J, Crother T, Bickel PE, Nel A. Proteome analysis of lipid rafts in Jurkat cells characterizes a raft subset that is involved in NF-kappaB activation. J Proteome Res. 2004 May-Jun; 3(3):445-54. PMID: 15253425.
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    183. Norris AJ, Whitelegge J, Strouse MJ, Faull KF, Toyokuni T. Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism. Bioorg Med Chem Lett. 2004 Feb 09; 14(3):571-3. PMID: 14741245.
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    184. Yohannan S, Faham S, Yang D, Whitelegge J, Bowie JU. The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc Natl Acad Sci U S A. 2004 Jan 27; 101(4):959-63. PMID: 14732697; PMCID: PMC327124.
    185. Faham S, Yang D, Bare E, Yohannan S, Whitelegge J, Bowie JU. Side-chain contributions to membrane protein structure and stability. J Mol Biol. 2004 Jan 02; 335(1):297-305. PMID: 14659758.
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    186. Whitelegge J. HPLC and mass spectrometry of intrinsic membrane proteins. Methods Mol Biol. 2004; 251:323-40. PMID: 14704455.
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    187. Bortz E, Whitelegge J, Jia Q, Zhou ZH, Stewart JP, Wu TT, Sun R. Identification of proteins associated with murine gammaherpesvirus 68 virions. J Virol. 2003 Dec; 77(24):13425-32. PMID: 14645600; PMCID: PMC296060.
    188. Gómez SM, Bil' KY, Aguilera R, Nishio JN, Faull KF, Whitelegge J. Transit peptide cleavage sites of integral thylakoid membrane proteins. Mol Cell Proteomics. 2003 Oct; 2(10):1068-85. PMID: 12902551.
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    189. Slaughter N, Laux I, Tu X, Whitelegge J, Zhu X, Effros R, Bickel P, Nel A. The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation. Clin Immunol. 2003 Aug; 108(2):138-51. PMID: 12921760.
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    190. Shau H, Chandler GS, Whitelegge J, Gornbein JA, Faull KF, Chang HR. Proteomic profiling of cancer biomarkers. Brief Funct Genomic Proteomic. 2003 Jul; 2(2):147-58. PMID: 15239937.
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    191. Whitelegge J, Ahn V, Norris AJ, Sung H, Waring A, Stevens RL, Fluharty CB, Prive G, Faull KF, Fluharty AL. Characterization of a recombinant molecule covalently indistinguishable from human cerebroside-sulfate activator protein (CSAct or Saposin B). Cell Mol Biol (Noisy-le-grand). 2003 Jul; 49(5):799-807. PMID: 14528917.
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    192. Kinzie SD, Thevis M, Ngo K, Whitelegge J, Loo JA, Abu-Omar MM. Posttranslational hydroxylation of human phenylalanine hydroxylase is a novel example of enzyme self-repair within the second coordination sphere of catalytic iron. J Am Chem Soc. 2003 Apr 23; 125(16):4710-1. PMID: 12696880.
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    193. Weinglass AB, Whitelegge J, Hu Y, Verner GE, Faull KF, Kaback HR. Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry. EMBO J. 2003 Apr 01; 22(7):1467-77. PMID: 12660154; PMCID: PMC152890.
    194. Whitelegge J. Thylakoid membrane proteomics. Photosynth Res. 2003; 78(3):265-77. PMID: 16245055.
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    195. Whitelegge J, Gómez SM, Faull KF. Proteomics of membrane proteins. Adv Protein Chem. 2003; 65:271-307. PMID: 12964373.
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    196. Ahn VE, Faull KF, Whitelegge J, Higginson J, Fluharty AL, Privé GG. Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B. Protein Expr Purif. 2003 Jan; 27(1):186-93. PMID: 12510003.
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    197. Ahn VE, Faull KF, Whitelegge J, Fluharty AL, Privé GG. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):38-43. PMID: 12518053; PMCID: PMC140876.
    198. Behnam K, Murray SS, Whitelegge J, Brochmann EJ. Identification of the molecular chaperone alpha B-crystallin in demineralized bone powder and osteoblast-like cells. J Orthop Res. 2002 Nov; 20(6):1190-6. PMID: 12472228.
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    199. Whitelegge J, Zhang H, Aguilera R, Taylor RM, Cramer WA. Full subunit coverage liquid chromatography electrospray ionization mass spectrometry (LCMS+) of an oligomeric membrane protein: cytochrome b(6)f complex from spinach and the cyanobacterium Mastigocladus laminosus. Mol Cell Proteomics. 2002 Oct; 1(10):816-27. PMID: 12438564.
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    200. Whitelegge J. Plant proteomics: BLASTing out of a MudPIT. Proc Natl Acad Sci U S A. 2002 Sep 03; 99(18):11564-6. PMID: 12195024; PMCID: PMC129307.
    201. Gómez SM, Nishio JN, Faull KF, Whitelegge J. The chloroplast grana proteome defined by intact mass measurements from liquid chromatography mass spectrometry. Mol Cell Proteomics. 2002 Jan; 1(1):46-59. PMID: 12096140.
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    202. Norris AJ, Whitelegge J, Faull KF, Toyokuni T. Kinetic characterization of enzyme inhibitors using electrospray-ionization mass spectrometry coupled with multiple reaction monitoring. Anal Chem. 2001 Dec 15; 73(24):6024-9. PMID: 11791575.
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    203. Schroda M, Vallon O, Whitelegge J, Beck CF, Wollman FA. The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differential splicing. Plant Cell. 2001 Dec; 13(12):2823-39. PMID: 11752390; PMCID: PMC139491.
    204. Zhang H, Whitelegge J, Cramer WA. Ferredoxin:NADP+ oxidoreductase is a subunit of the chloroplast cytochrome b6f complex. J Biol Chem. 2001 Oct 12; 276(41):38159-65. PMID: 11483610.
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    205. Suhr ST, Senut MC, Whitelegge J, Faull KF, Cuizon DB, Gage FH. Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression. J Cell Biol. 2001 Apr 16; 153(2):283-94. PMID: 11309410; PMCID: PMC2169460.
    206. Norris AJ, Whitelegge J, Faull KF, Toyokuni T. Analysis of enzyme kinetics using electrospray ionization mass spectrometry and multiple reaction monitoring: fucosyltransferase V. Biochemistry. 2001 Apr 03; 40(13):3774-9. PMID: 11300757.
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    207. Whitelegge J, le Coutre J. Proteomics. Making sense of genomic information for drug discovery. Am J Pharmacogenomics. 2001; 1(1):29-35. PMID: 12173311.
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    208. Fluharty CB, Johnson J, Whitelegge J, Faull KF, Fluharty AL. Comparative lipid binding study on the cerebroside sulfate activator (saposin B). J Neurosci Res. 2001 Jan 01; 63(1):82-9. PMID: 11169617.
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    209. Faull KF, Johnson J, Kim MJ, To T, Whitelegge J, Stevens RL, Fluharty CB, Fluharty AL. Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein. J Mass Spectrom. 2000 Dec; 35(12):1416-24. PMID: 11180632.
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    210. Whitelegge J, Penn B, To T, Johnson J, Waring A, Sherman M, Stevens RL, Fluharty CB, Faull KF, Fluharty AL. Methionine oxidation within the cerebroside-sulfate activator protein (CSAct or Saposin B). Protein Sci. 2000 Sep; 9(9):1618-30. PMID: 11045609; PMCID: PMC2144706.
    211. Turk E, Kim O, le Coutre J, Whitelegge J, Eskandari S, Lam JT, Kreman M, Zampighi G, Faull KF, Wright EM. Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters. J Biol Chem. 2000 Aug 18; 275(33):25711-6. PMID: 10835424.
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    212. le Coutre J, Whitelegge J, Gross A, Turk E, Wright EM, Kaback HR, Faull KF. Proteomics on full-length membrane proteins using mass spectrometry. Biochemistry. 2000 Apr 18; 39(15):4237-42. PMID: 10757971.
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    213. Faull KF, Higginson J, Waring AJ, Johnson J, To T, Whitelegge J, Stevens RL, Fluharty CB, Fluharty AL. Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity or alpha-helical content but is necessary for trypsin resistance and strong ligand binding. Arch Biochem Biophys. 2000 Apr 15; 376(2):266-74. PMID: 10775412.
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    214. Faull KF, Higginson J, Waring AJ, To T, Whitelegge J, Stevens RL, Fluharty CB, Fluharty AL. Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein. J Mass Spectrom. 2000 Mar; 35(3):392-401. PMID: 10767769.
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    215. Fluharty AL, Lombardo C, Louis A, Stevens RL, Whitelegge J, Waring AJ, To T, Fluharty CB, Faull KF. Preparation of the cerebroside sulfate activator (CSAct or saposin B) from human urine. Mol Genet Metab. 1999 Nov; 68(3):391-403. PMID: 10562467.
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    216. Faull KF, Whitelegge J, Higginson J, To T, Johnson J, Krutchinsky AN, Standing KG, Waring AJ, Stevens RL, Fluharty CB, Fluharty AL. Cerebroside sulfate activator protein (Saposin B): chromatographic and electrospray mass spectrometric properties. J Mass Spectrom. 1999 Oct; 34(10):1040-54. PMID: 10510427.
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    217. Whitelegge J, le Coutre J, Lee JC, Engel CK, Privé GG, Faull KF, Kaback HR. Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins. Proc Natl Acad Sci U S A. 1999 Sep 14; 96(19):10695-8. PMID: 10485888; PMCID: PMC17945.
    218. Blanco DR, Whitelegge J, Miller JN, Lovett MA. Demonstration by mass spectrometry that purified native Treponema pallidum rare outer membrane protein 1 (Tromp1) has a cleaved signal peptide. J Bacteriol. 1999 Aug; 181(16):5094-8. PMID: 10438785; PMCID: PMC94002.
    219. Mastrogiacomo A, Kohan SA, Whitelegge J, Gundersen CB. Intrinsic membrane association of Drosophila cysteine string proteins. FEBS Lett. 1998 Sep 25; 436(1):85-91. PMID: 9771899.
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    220. Whitelegge J, Gundersen CB, Faull KF. Electrospray-ionization mass spectrometry of intact intrinsic membrane proteins. Protein Sci. 1998 Jun; 7(6):1423-30. PMID: 9655347; PMCID: PMC2144037.
    221. Whitelegge J, Koo D, Diner BA, Domian I, Erickson JM. Assembly of the Photosystem II oxygen-evolving complex is inhibited in psbA site-directed mutants of Chlamydomonas reinhardtii. Aspartate 170 of the D1 polypeptide. J Biol Chem. 1995 Jan 06; 270(1):225-35. PMID: 7814379.
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    222. Whitelegge J, Jewess P, Pickering MG, Gerrish C, Camilleri P, Bowyer JR. Sequence analysis of photoaffinity-labelled peptides derived by proteolysis of photosystem-2 reaction centres from thylakoid membranes treated with [14C]azidoatrazine. Eur J Biochem. 1992 Aug 01; 207(3):1077-84. PMID: 1499553.
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    223. Bowyer JR, Packer JC, McCormack BA, Whitelegge J, Robinson C, Taylor MA. Carboxyl-terminal processing of the D1 protein and photoactivation of water-splitting in photosystem II. Partial purification and characterization of the processing enzyme from Scenedesmus obliquus and Pisum sativum. J Biol Chem. 1992 Mar 15; 267(8):5424-33. PMID: 1544920.
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    224. Bowyer J, Hilton M, Whitelegge J, Jewess P, Camilleri P, Crofts A, Robinson H. Molecular modelling studies on the binding of phenylurea inhibitors to the D 1 protein of photosystem II. Z Naturforsch C. 1990 May; 45(5):379-87. PMID: 2116126.
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