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Wasserman Karl R.

Title(s)Professor Emeritus, RESPIRATORY & CRITICAL CARE PHYSIOLOGY & MEDICINE
SchoolLABioMed
Phone(310) 222-3803
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kisaka T, Stringer WW, Koike A, Agostoni P, Wasserman K. Mechanisms That Modulate Peripheral Oxygen Delivery during Exercise in Heart Failure. Ann Am Thorac Soc. 2017 Jul; 14(Supplement_1):S40-S47. PMID: 28679061.
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    2. Yao YX, Sun XG, Zheng Z, Wang GZ, Hansen JE, Stringer WW, Wasserman K, Hu SS. Better parameters of ventilation-CO2output relationship predict death in CHF patients. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Nov; 31(6):508-16. PMID: 27215018.
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    3. Wasserman K, Kisaka T, Luehrs RE, Bates ML, Kumar VH, Lopez-Barneo J, Zuo L, Zhou T, Ni L, Brain J, Banzett R, Chamoun N. Commentaries on Viewpoint: Why do some patients stop breathing after taking narcotics? Ventilatory chemosensitivity as a predictor of opioid-induced respiratory depression. J Appl Physiol (1985). 2015 Aug 15; 119(4):423-5. PMID: 26276975.
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    4. Kisaka T, Cox TA, Dumitrescu D, Wasserman K. CO2 pulse and acid-base status during increasing work rate exercise in health and disease. Respir Physiol Neurobiol. 2015 Nov; 218:46-56. PMID: 26226561.
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    5. Tomita Y, Kasai T, Kisaka T, Rossiter HB, Kihara Y, Wasserman K, Daida H. Altered breathing syndrome in heart failure: newer insights and treatment options. Curr Heart Fail Rep. 2015 Apr; 12(2):158-65. PMID: 25576448.
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    6. Kisaka T, Rossiter HB, Wasserman K, Kihara Y. Exercise oscillatory ventilation: ventilation-perfusion abnormality in heart failure. Int J Cardiol. 2015 Apr 15; 185:55. PMID: 25804348.
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    7. Nagayama O, Koike A, Himi T, Sakurada K, Kato Y, Suzuki S, Sato A, Yamashita T, Wasserman K, Aonuma K. Clinical significance of a spiral phenomenon in the plot of CO2 output versus O2 uptake during exercise in cardiac patients. Am J Cardiol. 2015 Mar 01; 115(5):691-6. PMID: 25591892.
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    8. Wasserman K, Cox TA, Sietsema KE. Ventilatory regulation of arterial H(+) (pH) during exercise. Respir Physiol Neurobiol. 2014 Jan 01; 190:142-8. PMID: 24369924.
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    9. Kato J, Koike A, Hoshimoto-Iwamoto M, Nagayama O, Sakurada K, Sato A, Yamashita T, Wasserman K, Aonuma K. Relation between oscillatory breathing and cardiopulmonary function during exercise in cardiac patients. Circ J. 2013; 77(3):661-6. PMID: 23229462.
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    10. Kano H, Koike A, Hoshimoto-Iwamoto M, Nagayama O, Sakurada K, Suzuki T, Tsuneoka H, Sawada H, Aizawa T, Wasserman K. Abnormal end-tidal PO(2) and PCO(2) at the anaerobic threshold correlate well with impaired exercise gas exchange in patients with left ventricular dysfunction. Circ J. 2012; 76(1):79-87. PMID: 22094908.
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    11. Yount NY, Cohen SE, Kupferwasser D, Waring AJ, Ruchala P, Sharma S, Wasserman K, Jung CL, Yeaman MR. Context mediates antimicrobial efficacy of kinocidin congener peptide RP-1. PLoS One. 2011; 6(11):e26727. PMID: 22073187; PMCID: PMC3208557.
    12. Wasserman K, Beaver WL, Sun XG, Stringer WW. Arterial H+ regulation during exercise in humans. Respir Physiol Neurobiol. 2011 Sep 15; 178(2):191-5. PMID: 21689788.
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    13. Boutou AK, Pitsiou GG, Trigonis I, Papakosta D, Kontou PK, Chavouzis N, Nakou C, Argyropoulou P, Wasserman K, Stanopoulos I. Exercise capacity in idiopathic pulmonary fibrosis: the effect of pulmonary hypertension. Respirology. 2011 Apr; 16(3):451-8. PMID: 21122030.
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    14. Dumitrescu D, Oudiz RJ, Karpouzas G, Hovanesyan A, Jayasinghe A, Hansen JE, Rosenkranz S, Wasserman K. Developing pulmonary vasculopathy in systemic sclerosis, detected with non-invasive cardiopulmonary exercise testing. PLoS One. 2010 Dec 13; 5(12):e14293. PMID: 21179195; PMCID: PMC3001444.
    15. Chaudhry S, Arena RA, Hansen JE, Lewis GD, Myers JN, Sperling LS, Labudde BD, Wasserman K. The utility of cardiopulmonary exercise testing to detect and track early-stage ischemic heart disease. Mayo Clin Proc. 2010 Oct; 85(10):928-32. PMID: 20884826.
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    16. Sun XG, Hansen JE, Beshai JF, Wasserman K. Oscillatory breathing and exercise gas exchange abnormalities prognosticate early mortality and morbidity in heart failure. J Am Coll Cardiol. 2010 Apr 27; 55(17):1814-23. PMID: 20413031.
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    17. Oudiz RJ, Midde R, Hovenesyan A, Sun XG, Roveran G, Hansen JE, Wasserman K. Usefulness of right-to-left shunting and poor exercise gas exchange for predicting prognosis in patients with pulmonary arterial hypertension. Am J Cardiol. 2010 Apr 15; 105(8):1186-91. PMID: 20381675; PMCID: PMC3031421.
    18. Tin C, Wasserman K, Cherniack NS, Poon CS. Paradoxical potentiation of exercise hyperpnea in congestive heart failure contradicts Sherrington chemoreflex model and supports a respiratory optimization model. Adv Exp Med Biol. 2010; 669:69-72. PMID: 20217324.
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    19. Tajima A, Itoh H, Osada N, Omiya K, Maeda T, Ohkoshi N, Kawara T, Aizawa T, Wasserman K. Oxygen uptake kinetics during and after exercise are useful markers of coronary artery disease in patients with exercise electrocardiography suggesting myocardial ischemia. Circ J. 2009 Oct; 73(10):1864-70. PMID: 19661720.
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    20. Chaudhry S, Arena R, Wasserman K, Hansen JE, Lewis GD, Myers J, Belardinelli R, LaBudde B, Menasco N, Boden WE. The utility of cardiopulmonary exercise testing in the assessment of suspected microvascular ischemia. Int J Cardiol. 2011 Apr 01; 148(1):e7-9. PMID: 19233492.
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    21. Robbins JL, Duscha BD, Bensimhon DR, Wasserman K, Hansen JE, Houmard JA, Annex BH, Kraus WE. A sex-specific relationship between capillary density and anaerobic threshold. J Appl Physiol (1985). 2009 Apr; 106(4):1181-6. PMID: 19164774.
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    22. Chaudhry S, Arena R, Wasserman K, Hansen JE, Lewis GD, Myers J, Chronos N, Boden WE. Exercise-induced myocardial ischemia detected by cardiopulmonary exercise testing. Am J Cardiol. 2009 Mar 01; 103(5):615-9. PMID: 19231322.
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    23. Cattadori G, Wasserman K, Meloni C, Mustaq S, Contini M, Apostolo A, Andreini D, Magrì D, Sciomer S, Veglia F, Berna G, Introcaso G, Palermo P, Fiorentini C, Agostoni P. Alveolar membrane conductance decreases as BNP increases during exercise in heart failure. Rationale for BNP in the evaluation of dyspnea. J Card Fail. 2009 Mar; 15(2):136-44. PMID: 19254673.
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    24. Hansen JE, Sun XG, Adame D, Wasserman K. Argument for changing criteria for bronchodilator responsiveness. Respir Med. 2008 Dec; 102(12):1777-83. PMID: 18701269.
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    25. Hoshimoto-Iwamoto M, Koike A, Nagayama O, Tajima A, Uejima T, Adachi H, Aizawa T, Wasserman K. Determination of the V.E/V.CO2 slope from a constant work-rate exercise test in cardiac patients. J Physiol Sci. 2008 Aug; 58(4):291-5. PMID: 18647443.
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    26. Oudiz RJ, Roveran G, Hansen JE, Sun XG, Wasserman K. Effect of sildenafil on ventilatory efficiency and exercise tolerance in pulmonary hypertension. Eur J Heart Fail. 2007 Sep; 9(9):917-21. PMID: 17707133; PMCID: PMC2071948.
    27. Hansen JE, Ulubay G, Chow BF, Sun XG, Wasserman K. Mixed-expired and end-tidal CO2 distinguish between ventilation and perfusion defects during exercise testing in patients with lung and heart diseases. Chest. 2007 Sep; 132(3):977-83. PMID: 17573506.
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    28. Wasserman K, Sun XG, Hansen JE. Effect of biventricular pacing on the exercise pathophysiology of heart failure. Chest. 2007 Jul; 132(1):250-61. PMID: 17505041.
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    29. Hansen JE, Sun XG, Wasserman K. Spirometric criteria for airway obstruction: Use percentage of FEV1/FVC ratio below the fifth percentile, not < 70%. Chest. 2007 Feb; 131(2):349-55. PMID: 17296632.
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    30. Hansen JE, Sun XG, Wasserman K. Ethnic- and sex-free formulae for detection of airway obstruction. Am J Respir Crit Care Med. 2006 Sep 01; 174(5):493-8. PMID: 16778160.
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    31. Hansen JE, Sun XG, Wasserman K. Discriminating measures and normal values for expiratory obstruction. Chest. 2006 Feb; 129(2):369-77. PMID: 16478854.
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    32. Oudiz RJ, Barst RJ, Hansen JE, Sun XG, Garofano R, Wu X, Wasserman K. Cardiopulmonary exercise testing and six-minute walk correlations in pulmonary arterial hypertension. Am J Cardiol. 2006 Jan 01; 97(1):123-6. PMID: 16377296.
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    33. Agostoni P, Cattadori G, Apostolo A, Contini M, Palermo P, Marenzi G, Wasserman K. Noninvasive measurement of cardiac output during exercise by inert gas rebreathing technique: a new tool for heart failure evaluation. J Am Coll Cardiol. 2005 Nov 01; 46(9):1779-81. PMID: 16256885.
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    34. Agostoni P, Bianchi M, Moraschi A, Palermo P, Cattadori G, La Gioia R, Bussotti M, Wasserman K. Work-rate affects cardiopulmonary exercise test results in heart failure. Eur J Heart Fail. 2005 Jun; 7(4):498-504. PMID: 15921786.
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    35. Yasunobu Y, Oudiz RJ, Sun XG, Hansen JE, Wasserman K. End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension. Chest. 2005 May; 127(5):1637-46. PMID: 15888840.
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    36. Stringer WW, Wasserman K. Statement on exercise: American College of Chest Physicians/American Thoracic Society--exercise for fun or profit? Chest. 2005 Mar; 127(3):1072-3; author reply 1073-4. PMID: 15764797.
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    37. Oudiz RJ, Wasserman K. Clinical efficacy of sildenafil in primary pulmonary hypertension. J Am Coll Cardiol. 2004 Dec 07; 44(11):2256; author reply 2256-7. PMID: 15582332.
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    38. Stringer WW, Whipp BJ, Wasserman K, Pórszász J, Christenson P, French WJ. Non-linear cardiac output dynamics during ramp-incremental cycle ergometry. Eur J Appl Physiol. 2005 Mar; 93(5-6):634-9. PMID: 15578205.
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    39. Hansen JE, Sun XG, Yasunobu Y, Garafano RP, Gates G, Barst RJ, Wasserman K. Reproducibility of cardiopulmonary exercise measurements in patients with pulmonary arterial hypertension. Chest. 2004 Sep; 126(3):816-24. PMID: 15364761.
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    40. Ong HY, O'Dochartaigh CS, Lovell S, Patterson VH, Wasserman K, Nicholls DP, Riley MS. Gas exchange responses to constant work-rate exercise in patients with glycogenosis type V and VII. Am J Respir Crit Care Med. 2004 Jun 01; 169(11):1238-44. PMID: 15070817.
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    41. Lau AC, Lo MK, Leung GT, Choi FP, Yam LY, Wasserman K. Altered exercise gas exchange as related to microalbuminuria in type 2 diabetic patients. Chest. 2004 Apr; 125(4):1292-8. PMID: 15078737.
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    42. Agostoni P, Cattadori G, Bianchi M, Wasserman K. Exercise-induced pulmonary edema in heart failure. Circulation. 2003 Nov 25; 108(21):2666-71. PMID: 14581402.
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    43. Barst RJ, McGoon M, McLaughlin V, Tapson V, Rich S, Rubin L, Wasserman K, Oudiz R, Shapiro S, Robbins IM, Channick R, Badesch D, Rayburn BK, Flinchbaugh R, Sigman J, Arneson C, Jeffs R. Beraprost therapy for pulmonary arterial hypertension. J Am Coll Cardiol. 2003 Jun 18; 41(12):2119-25. PMID: 12821234.
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    44. Sun XG, Hansen JE, Oudiz RJ, Wasserman K. Pulmonary function in primary pulmonary hypertension. J Am Coll Cardiol. 2003 Mar 19; 41(6):1028-35. PMID: 12651053.
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    45. Gitt AK, Wasserman K, Kilkowski C, Kleemann T, Kilkowski A, Bangert M, Schneider S, Schwarz A, Senges J. Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death. Circulation. 2002 Dec 10; 106(24):3079-84. PMID: 12473555.
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    46. Sun XG, Hansen JE, Garatachea N, Storer TW, Wasserman K. Ventilatory efficiency during exercise in healthy subjects. Am J Respir Crit Care Med. 2002 Dec 01; 166(11):1443-8. PMID: 12450934.
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    47. Chuang ML, Ting H, Otsuka T, Sun XG, Chiu FY, Hansen JE, Wasserman K. Muscle deoxygenation as related to work rate. Med Sci Sports Exerc. 2002 Oct; 34(10):1614-23. PMID: 12370563.
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    48. Wasserman K. Mitochondrial disorders and exertional intolerance: controversy continues. Am J Respir Crit Care Med. 2002 Jul 01; 166(1):118; author reply 119-20. PMID: 12118471.
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    49. Wasserman K. Exercise gas exchange, breath-by-breath. Am J Respir Crit Care Med. 2002 Feb 01; 165(3):325-6. PMID: 11818314.
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    50. Sun XG, Hansen JE, Oudiz RJ, Wasserman K. Gas exchange detection of exercise-induced right-to-left shunt in patients with primary pulmonary hypertension. Circulation. 2002 Jan 01; 105(1):54-60. PMID: 11772876.
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