Bajaj Madhu

Title(s)Assistant Professor, David Geffen School of Medicine at UCLA
Phone(310) 825-8061
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    Collapse Research 
    Collapse Research Activities and Funding
    Efficacy of Kunitz Domain 1 variants of TFPI-2 as novel antifibrinolytic agents
    NIH/NHLBI R21HL089661Apr 1, 2009 - Mar 31, 2012
    Role: Principal Investigator
    NIH/NHLBI K08HL003237Jul 1, 1996 - Jun 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Vadivel K, Kumar Y, Bunce MW, Camire RM, Bajaj MS, Bajaj SP. Interaction of factor V B-domain acidic region with its basic region and with TFPI/TFPI2: Structural insights from molecular modeling studies. Int Biol Rev. 2017 May; 1(1). PMID: 28845483.
      View in: PubMed
    2. Vadivel K, Ponnuraj SM, Kumar Y, Zaiss AK, Bunce MW, Camire RM, Wu L, Evseenko D, Herschman HR, Bajaj MS, Bajaj SP. Platelets contain tissue factor pathway inhibitor-2 derived from megakaryocytes and inhibits fibrinolysis. J Biol Chem. 2014 Nov 07; 289(45):31647-61. PMID: 25262870; PMCID: PMC4223360.
    3. Kumar Y, Vadivel K, Schmidt AE, Ogueli GI, Ponnuraj SM, Rannulu N, Loo JA, Bajaj MS, Bajaj SP. Decoy plasminogen receptor containing a selective Kunitz-inhibitory domain. Biochemistry. 2014 Jan 28; 53(3):505-17. PMID: 24383758; PMCID: PMC3985851.
    4. Vadivel K, Agah S, Messer AS, Cascio D, Bajaj MS, Krishnaswamy S, Esmon CT, Padmanabhan K, Bajaj SP. Structural and functional studies of ?-carboxyglutamic acid domains of factor VIIa and activated Protein C: role of magnesium at physiological calcium. J Mol Biol. 2013 Jun 12; 425(11):1961-1981. PMID: 23454357.
      View in: PubMed
    5. Bajaj MS, Ogueli GI, Kumar Y, Vadivel K, Lawson G, Shanker S, Schmidt AE, Bajaj SP. Engineering kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variant. J Biol Chem. 2011 Feb 11; 286(6):4329-40. PMID: 21115497; PMCID: PMC3039392.
    6. Bajaj MS, Ghosh M, Bajaj SP. Fibronectin-adherent monocytes express tissue factor and tissue factor pathway inhibitor whereas endotoxin-stimulated monocytes primarily express tissue factor: physiologic and pathologic implications. J Thromb Haemost. 2007 Jul; 5(7):1493-9. PMID: 17470199.
      View in: PubMed
    7. Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25; 281(34):24873-88. PMID: 16757484.
      View in: PubMed
    8. Espiritu JD, Creer MH, Miklos AZ, Bajaj MS. Fatal tumor thrombosis due to an inferior vena cava leiomyosarcoma in a patient with antiphospholipid antibody syndrome. Mayo Clin Proc. 2002 Jun; 77(6):595-9. PMID: 12059132.
      View in: PubMed
    9. Zhong D, Bajaj MS, Schmidt AE, Bajaj SP. The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor. J Biol Chem. 2002 Feb 01; 277(5):3622-31. PMID: 11723140.
      View in: PubMed