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Ajijola Olujimi A

Title(s)Member, CTSI
Phone3102066433
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    Other Positions
    Title(s)Member, Molecular Cellular & Integrative Physiology GPB Home Area

    Title(s)Assistant Professor In-Residence, UCLA Cardiac Arrhythmia Center


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nguyen KL, Shao J, Ghodrati VK, Ajijola OA, Dharmakumar R, Finn JP, Hu P. Ferumoxytol-Enhanced CMR for Vasodilator Stress Testing: A Feasibility Study. JACC Cardiovasc Imaging. 2019 Mar 08. PMID: 30878418.
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    2. Williams CS, Iness AN, Baron RM, Ajijola OA, Hu PJ, Vyas JM, Baiocchi R, Adami AJ, Lever JM, Klein PS, Demer L, Madaio M, Geraci M, Brass LF, Blanchard M, Salata R, Zaidi M. Training the physician-scientist: views from program directors and aspiring young investigators. JCI Insight. 2018 Dec 06; 3(23). PMID: 30518696.
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    3. Wunderly K, Yousef Z, Bonny A, Weatherwax KJ, Lavan B, Allmendinger C, Wasserman B, Samson G, Davis S, Nel G, Russell J, Akwanalo C, Sani MU, Chin A, Ajijola OA, Mayosi BM, Eagle KA, Crawford TC. Using reconditioned pacemakers to treat bradycardia in Africa. Nat Rev Cardiol. 2018 Dec; 15(12):725-726. PMID: 30209354.
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    4. Chadda KR, Ajijola OA, Vaseghi M, Shivkumar K, Huang CL, Jeevaratnam K. Ageing, the autonomic nervous system and arrhythmia: From brain to heart. Ageing Res Rev. 2018 Dec; 48:40-50. PMID: 30300712.
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    5. Bardsley EN, Davis H, Ajijola OA, Buckler KJ, Ardell JL, Shivkumar K, Paterson DJ. RNA Sequencing Reveals Novel Transcripts from Sympathetic Stellate Ganglia During Cardiac Sympathetic Hyperactivity. Sci Rep. 2018 Jun 05; 8(1):8633. PMID: 29872217.
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    6. Liu K, Li D, Hao G, McCaffary D, Neely O, Woodward L, Ioannides D, Lu CJ, Brescia M, Zaccolo M, Tandri H, Ajijola OA, Ardell JL, Shivkumar K, Paterson DJ. Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity. JCI Insight. 2018 May 03; 3(9). PMID: 29720569.
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    7. Dusi V, Ajijola OA. Estimating Cardiac Sympathetic Activity From Subcutaneous Nerve Recordings: More Than Skin Deep? JACC Clin Electrophysiol. 2018 May; 4(5):696-698. PMID: 29798800.
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    8. Meng L, Shivkumar K, Ajijola O. Autonomic Regulation and Ventricular Arrhythmias. Curr Treat Options Cardiovasc Med. 2018 Apr 07; 20(5):38. PMID: 29627871.
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    9. Huang WA, Wassie MA, Ajijola OA. Permanent His Bundle Pacing for Cardiac Resynchronization. Curr Treat Options Cardiovasc Med. 2018 Mar 06; 20(3):23. PMID: 29508149.
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    10. Kwon OJ, Pendekanti S, Fox JN, Yanagawa J, Fishbein MC, Shivkumar K, Lambert HW, Ajijola OA. Morphological Spectra of Adult Human Stellate Ganglia: Implications for Thoracic Sympathetic Denervation. Anat Rec (Hoboken). 2018 Feb 16. PMID: 29451372.
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    11. Bradfield JS, Ajijola OA, Vaseghi M, Shivkumar K. Mechanisms and management of refractory ventricular arrhythmias in the age of autonomic modulation. Heart Rhythm. 2018 08; 15(8):1252-1260. PMID: 29454137.
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    12. Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA. Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress. Am J Physiol Heart Circ Physiol. 2018 05 01; 314(5):H954-H966. PMID: 29351450.
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    13. Li A, Hayase J, Do D, Buch E, Vaseghi M, Ajijola OA, Macias C, Krokhaleva Y, Khakpour H, Boyle NG, Benharash P, Biniwale R, Shivkumar K, Bradfield JS. Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation. Heart Rhythm. 2018 04; 15(4):512-519. PMID: 29132931.
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    14. Do DH, Bradfield J, Ajijola OA, Vaseghi M, Le J, Rahman S, Mahajan A, Nogami A, Boyle NG, Shivkumar K. Thoracic Epidural Anesthesia Can Be Effective for the Short-Term Management of Ventricular Tachycardia Storm. J Am Heart Assoc. 2017 Oct 27; 6(11). PMID: 29079570.
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    15. Yoshie K, Ajijola OA. Managing ventricular arrhythmias after failed catheter ablation: Interrupting the reentrant loop of repeat ablation. Heart Rhythm. 2018 01; 15(1):63-64. PMID: 28958931.
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    16. Ajijola OA, Hoover DB, Simerly TM, Brown TC, Yanagawa J, Biniwale RM, Lee JM, Sadeghi A, Khanlou N, Ardell JL, Shivkumar K. Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm. JCI Insight. 2017 Sep 21; 2(18). PMID: 28931760.
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    17. Meng L, Tseng CH, Shivkumar K, Ajijola O. Efficacy of Stellate Ganglion Blockade in Managing Electrical Storm: A Systematic Review. JACC Clin Electrophysiol. 2017 Sep; 3(9):942-949. PMID: 29270467.
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    18. Hanna P, Rajendran PS, Ajijola OA, Vaseghi M, Andrew Armour J, Ardell JL, Shivkumar K. Cardiac neuroanatomy - Imaging nerves to define functional control. Auton Neurosci. 2017 Nov; 207:48-58. PMID: 28802636.
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    19. Romero J, Ajijola O, Shivkumar K, Tung R. Characterization of Aortic Valve Closure Artifact During Outflow Tract Mapping: Correlation With Hemodynamics and Mechanical Valves. Circ Arrhythm Electrophysiol. 2017 Jun; 10(6). PMID: 28630170.
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    20. Ajijola OA, Upadhyay GA, Macias C, Shivkumar K, Tung R. Permanent His-bundle pacing for cardiac resynchronization therapy: Initial feasibility study in lieu of left ventricular lead. Heart Rhythm. 2017 09; 14(9):1353-1361. PMID: 28400315.
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    21. Hamon D, Rajendran PS, Chui RW, Ajijola OA, Irie T, Talebi R, Salavatian S, Vaseghi M, Bradfield JS, Armour JA, Ardell JL, Shivkumar K. Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping. Circ Arrhythm Electrophysiol. 2017 Apr; 10(4). PMID: 28408652.
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    22. Ajijola OA, Lux RL, Khahera A, Kwon O, Aliotta E, Ennis DB, Fishbein MC, Ardell JL, Shivkumar K. Sympathetic modulation of electrical activation in normal and infarcted myocardium: implications for arrhythmogenesis. Am J Physiol Heart Circ Physiol. 2017 Mar 01; 312(3):H608-H621. PMID: 28087519.
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    23. Ajijola OA, Shivkumar K, Habecker BA. Natriuretic peptides and peripheral autonomic neurotransmission: back to the A, B, and C's. Cardiovasc Res. 2016 12; 112(3):619-621. PMID: 27979809.
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    24. Teng AE, Massoud L, Ajijola OA. Physiological mechanisms of QRS narrowing in bundle branch block patients undergoing permanent His bundle pacing. J Electrocardiol. 2016 Sep-Oct; 49(5):644-8. PMID: 27485351.
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    25. Tung R, Kim S, Yagishita D, Vaseghi M, Ennis DB, Ouadah S, Ajijola OA, Bradfield JS, Mahapatra S, Finn P, Shivkumar K. Scar voltage threshold determination using ex vivo magnetic resonance imaging integration in a porcine infarct model: Influence of interelectrode distances and three-dimensional spatial effects of scar. Heart Rhythm. 2016 10; 13(10):1993-2002. PMID: 27392944.
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    26. Shivkumar K, Ajijola OA, Anand I, Armour JA, Chen PS, Esler M, De Ferrari GM, Fishbein MC, Goldberger JJ, Harper RM, Joyner MJ, Khalsa SS, Kumar R, Lane R, Mahajan A, Po S, Schwartz PJ, Somers VK, Valderrabano M, Vaseghi M, Zipes DP. Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. J Physiol. 2016 07 15; 594(14):3911-54. PMID: 27114333; PMCID: PMC4945719 [Available on 07/15/17].
    27. Teng AE, Lustgarten DL, Vijayaraman P, Tung R, Shivkumar K, Wagner GS, Ajijola OA. Usefulness of His Bundle Pacing to Achieve Electrical Resynchronization in Patients With Complete Left Bundle Branch Block and the Relation Between Native QRS Axis, Duration, and Normalization. Am J Cardiol. 2016 08 15; 118(4):527-34. PMID: 27344272.
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    28. Nakamura K, Ajijola OA, Aliotta E, Armour JA, Ardell JL, Shivkumar K. Pathological effects of chronic myocardial infarction on peripheral neurons mediating cardiac neurotransmission. Auton Neurosci. 2016 05; 197:34-40. PMID: 27209472.
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    29. Mukku RB, Fonarow GC, Watson KE, Ajijola OA, Depasquale EC, Nsair A, Baas AS, Deng MC, Yang EH. Heart Failure Therapies for End-Stage Chemotherapy-Induced Cardiomyopathy. J Card Fail. 2016 Jun; 22(6):439-48. PMID: 27109619.
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    30. Te Riele AS, Ajijola OA, Shivkumar K, Tandri H. Role of Bilateral Sympathectomy in the Treatment of Refractory Ventricular Arrhythmias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy. Circ Arrhythm Electrophysiol. 2016 Apr; 9(4):e003713. PMID: 27030701.
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    31. Ajijola OA, Hamon D. NON-INVASIVE NEUROMODULATION VIA TRAGAL STIMULATION: TIME TO LEND AN EAR? JACC Clin Electrophysiol. 2016 Jun; 2(3):340-342. PMID: 27725967.
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    32. Rajendran PS, Nakamura K, Ajijola OA, Vaseghi M, Armour JA, Ardell JL, Shivkumar K. Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system. J Physiol. 2016 Jan 15; 594(2):321-41. PMID: 26572244; PMCID: PMC4713729 [Available on 01/15/17].
    33. Yamakawa K, Howard-Quijano K, Zhou W, Rajendran P, Yagishita D, Vaseghi M, Ajijola OA, Armour JA, Shivkumar K, Ardell JL, Mahajan A. Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology. Am J Physiol Regul Integr Comp Physiol. 2016 Mar 01; 310(5):R414-21. PMID: 26661096; PMCID: PMC4796738 [Available on 03/01/17].
    34. Romero J, Ajijola OA, Boyle N, Shivkumar K, Tung R. Prolonged high-power endocardial ablation of epicardial microreentrant VT from the LV summit in a patient with nonischemic cardiomyopathy. HeartRhythm Case Rep. 2015 Nov; 1(6):464-468. PMID: 28491608.
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    35. Ajijola OA, Romero J, Vorobiof G, Suh WM, Shivkumar K, Tung R. Hyper-response to cardiac resynchronization with permanent His bundle pacing: Is parahisian pacing sufficient? HeartRhythm Case Rep. 2015 Nov; 1(6):429-433. PMID: 27722091.
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    36. Tung R, Bauer B, Schelbert H, Lynch JP, Auerbach M, Gupta P, Schiepers C, Chan S, Ferris J, Barrio M, Ajijola O, Bradfield J, Shivkumar K. Incidence of abnormal positron emission tomography in patients with unexplained cardiomyopathy and ventricular arrhythmias: The potential role of occult inflammation in arrhythmogenesis. Heart Rhythm. 2015 Dec; 12(12):2488-98. PMID: 26272522; PMCID: PMC4656080 [Available on 12/01/16].
    37. Ajijola OA. Sudden cardiac death: We are not there yet. Trends Cardiovasc Med. 2016 Jan; 26(1):34-5. PMID: 25983074.
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    38. Ajijola OA, Boyle NG, Shivkumar K. Detecting and monitoring arrhythmia recurrence following catheter ablation of atrial fibrillation. Front Physiol. 2015; 6:90. PMID: 25870562; PMCID: PMC4376077.
    39. Irie T, Yu R, Bradfield JS, Vaseghi M, Buch EF, Ajijola O, Macias C, Fujimura O, Mandapati R, Boyle NG, Shivkumar K, Tung R. Relationship between sinus rhythm late activation zones and critical sites for scar-related ventricular tachycardia: systematic analysis of isochronal late activation mapping. Circ Arrhythm Electrophysiol. 2015 Apr; 8(2):390-9. PMID: 25740836.
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    40. Ajijola OA, Howard-Quijano K, Scovotti J, Vaseghi M, Lee C, Mahajan A, Shivkumar K. Augmentation of cardiac sympathetic tone by percutaneous low-level stellate ganglion stimulation in humans: a feasibility study. Physiol Rep. 2015 Mar; 3(3). PMID: 25804262; PMCID: PMC4393162.
    41. Ajijola OA, Yagishita D, Reddy NK, Yamakawa K, Vaseghi M, Downs AM, Hoover DB, Ardell JL, Shivkumar K. Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: Neuropeptide and morphologic changes. Heart Rhythm. 2015 May; 12(5):1027-35. PMID: 25640636; PMCID: PMC4411181.
    42. Yagishita D, Chui RW, Yamakawa K, Rajendran PS, Ajijola OA, Nakamura K, So EL, Mahajan A, Shivkumar K, Vaseghi M. Sympathetic nerve stimulation, not circulating norepinephrine, modulates T-peak to T-end interval by increasing global dispersion of repolarization. Circ Arrhythm Electrophysiol. 2015 Feb; 8(1):174-85. PMID: 25532528; PMCID: PMC4405126.
    43. Krishnamoorthi S, Perotti LE, Borgstrom NP, Ajijola OA, Frid A, Ponnaluri AV, Weiss JN, Qu Z, Klug WS, Ennis DB, Garfinkel A. Simulation Methods and Validation Criteria for Modeling Cardiac Ventricular Electrophysiology. PLoS One. 2014; 9(12):e114494. PMID: 25493967.
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    44. Truong QA, Januzzi JL, Szymonifka J, Thai WE, Wai B, Lavender Z, Sharma U, Sandoval RM, Grunau ZS, Basnet S, Babatunde A, Ajijola OA, Min JK, Singh JP. Coronary sinus biomarker sampling compared to peripheral venous blood for predicting outcomes in patients with severe heart failure undergoing cardiac resynchronization therapy: the BIOCRT study. Heart Rhythm. 2014 Dec; 11(12):2167-75. PMID: 25014756; PMCID: PMC4254015.
    45. Ajijola OA, Tung R, Shivkumar K. Ventricular tachycardia in ischemic heart disease substrates. Indian Heart J. 2014 Jan-Feb; 66 Suppl 1:S24-34. PMID: 24568826; PMCID: PMC4237298.
    46. Khalsa SS, Shahabi L, Ajijola OA, Bystritsky A, Naliboff BD, Shivkumar K. Synergistic application of cardiac sympathetic decentralization and comprehensive psychiatric treatment in the management of anxiety and electrical storm. Front Integr Neurosci. 2014; 7:98. PMID: 24427121; PMCID: PMC3878030.
    47. Vaseghi M, Gima J, Kanaan C, Ajijola OA, Marmureanu A, Mahajan A, Shivkumar K. Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias or electrical storm: intermediate and long-term follow-up. Heart Rhythm. 2014 Mar; 11(3):360-6. PMID: 24291775; PMCID: PMC4253031.
    48. Ajijola OA, Sun AY. The genetics of the J wave patterns. J Electrocardiol. 2013 Sep-Oct; 46(5):395-8. PMID: 23981304.
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    49. Ajijola OA, Yagishita D, Patel KJ, Vaseghi M, Zhou W, Yamakawa K, So E, Lux RL, Mahajan A, Shivkumar K. Focal myocardial infarction induces global remodeling of cardiac sympathetic innervation: neural remodeling in a spatial context. Am J Physiol Heart Circ Physiol. 2013 Oct 01; 305(7):H1031-40. PMID: 23893167; PMCID: PMC3798751.
    50. Vaseghi M, Yamakawa K, Sinha A, So EL, Zhou W, Ajijola OA, Lux RL, Laks M, Shivkumar K, Mahajan A. Modulation of regional dispersion of repolarization and T-peak to T-end interval by the right and left stellate ganglia. Am J Physiol Heart Circ Physiol. 2013 Oct 01; 305(7):H1020-30. PMID: 23893168; PMCID: PMC3798747.
    51. Yagishita D, Ajijola OA, Vaseghi M, Nsair A, Zhou W, Yamakawa K, Tung R, Mahajan A, Shivkumar K. Electrical homogenization of ventricular scar by application of collagenase: a novel strategy for arrhythmia therapy. Circ Arrhythm Electrophysiol. 2013 Aug; 6(4):776-83. PMID: 23873142; PMCID: PMC3872289.
    52. Zhou W, Yamakawa K, Benharash P, Ajijola O, Ennis D, Hadaya J, Vaseghi M, Shivkumar K, Mahajan A. Effect of stellate ganglia stimulation on global and regional left ventricular function as assessed by speckle tracking echocardiography. Am J Physiol Heart Circ Physiol. 2013 Mar 15; 304(6):H840-7. PMID: 23335795; PMCID: PMC3602776.
    53. Ajijola OA, Vaseghi M, Zhou W, Yamakawa K, Benharash P, Hadaya J, Lux RL, Mahajan A, Shivkumar K. Functional differences between junctional and extrajunctional adrenergic receptor activation in mammalian ventricle. Am J Physiol Heart Circ Physiol. 2013 Feb 15; 304(4):H579-88. PMID: 23241324; PMCID: PMC3566483.
    54. Ajijola OA, Wisco JJ, Lambert HW, Mahajan A, Stark E, Fishbein MC, Shivkumar K. Extracardiac neural remodeling in humans with cardiomyopathy. Circ Arrhythm Electrophysiol. 2012 Oct; 5(5):1010-116. PMID: 22923270; PMCID: PMC3529182.
    55. Ajijola OA, Vaseghi M, Mahajan A, Shivkumar K. Bilateral cardiac sympathetic denervation: why, who and when? Expert Rev Cardiovasc Ther. 2012 Aug; 10(8):947-9. PMID: 23030281; PMCID: PMC3551540.
    56. Ajijola OA, Shivkumar K. Neural remodeling and myocardial infarction: the stellate ganglion as a double agent. J Am Coll Cardiol. 2012 Mar 06; 59(10):962-4. PMID: 22381433; PMCID: PMC3536484.
    57. Zhou W, Ko Y, Benharash P, Yamakawa K, Patel S, Ajijola OA, Mahajan A. Cardioprotection of electroacupuncture against myocardial ischemia-reperfusion injury by modulation of cardiac norepinephrine release. Am J Physiol Heart Circ Physiol. 2012 May 01; 302(9):H1818-25. PMID: 22367505.
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    58. Ajijola OA, Lellouche N, Bourke T, Tung R, Ahn S, Mahajan A, Shivkumar K. Bilateral cardiac sympathetic denervation for the management of electrical storm. J Am Coll Cardiol. 2012 Jan 03; 59(1):91-2. PMID: 22192676; PMCID: PMC3470807.
    59. Ramirez RJ, Ajijola OA, Zhou W, Holmström B, Lüning H, Laks MM, Shivkumar K, Mahajan A. A new electrocardiographic marker for sympathetic nerve stimulation: modulation of repolarization by stimulation of stellate ganglia. J Electrocardiol. 2011 Nov-Dec; 44(6):694-9. PMID: 21917265.
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    60. Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ. Genetic and clinical correlates of early-outgrowth colony-forming units. Circ Cardiovasc Genet. 2011 Jun; 4(3):296-304. PMID: 21493818; PMCID: PMC3339257.
    61. Ajijola OA, Macklin EA, Moore SA, McCarty D, Bischoff KE, Heist EK, Picard M, Ruskin JN, Dec GW, Singh JP. Inpatient vs. elective outpatient cardiac resynchronization therapy device implantation and long-term clinical outcome. Europace. 2010 Dec; 12(12):1745-9. PMID: 20852289.
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    62. Ajijola OA, Dong C, Herderick EE, Ma Q, Goldschmidt-Clermont PJ, Yan Z. Voluntary running suppresses proinflammatory cytokines and bone marrow endothelial progenitor cell levels in apolipoprotein-E-deficient mice. Antioxid Redox Signal. 2009 Jan; 11(1):15-23. PMID: 18837653; PMCID: PMC2933158.
    63. Ajijola OA, Nandigam KV, Chabner BA, Orencole M, Dec GW, Ruskin JN, Singh JP. Usefulness of cardiac resynchronization therapy in the management of Doxorubicin-induced cardiomyopathy. Am J Cardiol. 2008 May 01; 101(9):1371-2. PMID: 18435975.
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    64. Ajijola OA, Goldschmidt-Clermont PJ, Satterwhite LL. CD40 ligand: not bad to the bone (marrow), after all. Arterioscler Thromb Vasc Biol. 2005 Jun; 25(6):1088-90. PMID: 15923539.
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