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Jacobsen Steven

TitleHHMI Investigator Department of Molecular Cell and Developmental Biology
InstitutionUniversity of California Los Angeles
DepartmentMolecular Cell and Developmental Biology
AddressDept. of MCD Biology
P. O. Box 957239
610 Charles E. Young Drive Eas
Los Angeles CA 90095
Phone(310) 206-3336
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    Other Positions
    TitleProfessor


    Collapse Research 
    Collapse Research Activities and Funding
    2007 Epigenetics Gordon Research Conference
    NIH/NICHD R13HD056518Jul 20, 2007 - Jun 30, 2008
    Role: Principal Investigator
    Genetics of DNA methylation patterning of arabidopsis.
    NIH/NIGMS R37GM060398Jan 1, 2000 - Dec 31, 2018
    Role: Principal Investigator
    Genetics of DNA Methylation Patterning of Arabidopsis
    NIH/NIGMS R01GM060398Jan 1, 2000 - Dec 31, 2008
    Role: Principal Investigator
    SPATIAL REGULATION OF A THALIANA FLORAL HOMEOTIC GENES
    NIH/NIGMS F32GM015964Sep 30, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yan Y, Liu Q, Zang X, Yuan S, Bat-Erdene U, Nguyen C, Gan J, Zhou J, Jacobsen S, Tang Y. Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. Nature. 2018 Jul 11. PMID: 29995859.
      View in: PubMed
    2. Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Epigenome-wide association in adipose tissue from the METSIM cohort. Hum Mol Genet. 2018 Jun 09. PMID: 29893869.
      View in: PubMed
    3. Orozco LD, Farrell C, Hale C, Rubbi L, Rinaldi A, Civelek M, Pan C, Lam L, Montoya D, Edillor C, Seldin M, Boehnke M, Mohlke KL, Jacobsen S, Kuusisto J, Laakso M, Lusis AJ, Pellegrini M. Epigenome-wide association in adipose tissue from the METSIM cohort. Hum Mol Genet. 2018 May 15; 27(10):1830-1846. PMID: 29566149.
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    4. Pastor WA, Liu W, Chen D, Ho J, Kim R, Hunt TJ, Lukianchikov A, Liu X, Polo JM, Jacobsen S, Clark AT. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nat Cell Biol. 2018 May; 20(5):553-564. PMID: 29695788.
      View in: PubMed
    5. Gallego-Bartolomé J, Gardiner J, Liu W, Papikian A, Ghoshal B, Kuo HY, Zhao JM, Segal DJ, Jacobsen S. Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain. Proc Natl Acad Sci U S A. 2018 Feb 27; 115(9):E2125-E2134. PMID: 29444862.
      View in: PubMed
    6. Liu W, Duttke SH, Hetzel J, Groth M, Feng S, Gallego-Bartolome J, Zhong Z, Kuo HY, Wang Z, Zhai J, Chory J, Jacobsen S. RNA-directed DNA methylation involves co-transcriptional small-RNA-guided slicing of polymerase V transcripts in Arabidopsis. Nat Plants. 2018 Mar; 4(3):181-188. PMID: 29379150.
      View in: PubMed
    7. Zhang Y, Harris CJ, Liu Q, Liu W, Ausin I, Long Y, Xiao L, Feng L, Chen X, Xie Y, Chen X, Zhan L, Feng S, Li JJ, Wang H, Zhai J, Jacobsen S. Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis. Proc Natl Acad Sci U S A. 2018 Jan 30; 115(5):E1069-E1074. PMID: 29339507.
      View in: PubMed
    8. Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen S, Pellegrini M. Correction: In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 2017 08 31; 6. PMID: 28858608.
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    9. Jensen NJ, Rivailler P, Tseng HF, Quinlivan ML, Radford K, Folster J, Harpaz R, LaRussa P, Jacobsen S, Scott Schmid D. Revisiting the genotyping scheme for varicella-zoster viruses based on whole-genome comparisons. J Gen Virol. 2017 Jun; 98(6):1434-1438. PMID: 28613146.
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    10. Weiser NE, Yang DX, Feng S, Kalinava N, Brown KC, Khanikar J, Freeberg MA, Snyder MJ, Csankovszki G, Chan RC, Gu SG, Montgomery TA, Jacobsen S, Kim JK. MORC-1 Integrates Nuclear RNAi and Transgenerational Chromatin Architecture to Promote Germline Immortality. Dev Cell. 2017 05 22; 41(4):408-423.e7. PMID: 28535375.
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    11. Wollmann H, Stroud H, Yelagandula R, Tarutani Y, Jiang D, Jing L, Jamge B, Takeuchi H, Holec S, Nie X, Kakutani T, Jacobsen S, Berger F. The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana. Genome Biol. 2017 05 18; 18(1):94. PMID: 28521766.
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    12. Johnson LM, Du J, Hale CJ, Bischof S, Feng S, Chodavarapu RK, Zhong X, Marson G, Pellegrini M, Segal DJ, Patel DJ, Jacobsen S. Corrigendum: SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature. 2017 03 02; 543(7643):136. PMID: 28178234.
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    13. Chen D, Liu W, Lukianchikov A, Hancock GV, Zimmerman J, Lowe MG, Kim R, Galic Z, Irie N, Surani MA, Jacobsen S, Clark AT. Germline competency of human embryonic stem cells depends on eomesodermin. Biol Reprod. 2017 Jan 01; 97(6):850-861. PMID: 29091993.
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    14. Feng W, Hale CJ, Over RS, Cokus SJ, Jacobsen S, Michaels SD. Large-scale heterochromatin remodeling linked to overreplication-associated DNA damage. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):406-411. PMID: 28028228.
      View in: PubMed
    15. Lahmy S, Pontier D, Bies-Etheve N, Laudié M, Feng S, Jobet E, Hale CJ, Cooke R, Hakimi MA, Angelov D, Jacobsen S, Lagrange T. Evidence for ARGONAUTE4-DNA interactions in RNA-directed DNA methylation in plants. Genes Dev. 2016 12 01; 30(23):2565-2570. PMID: 27986858.
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    16. Ausin I, Feng S, Yu C, Liu W, Kuo HY, Jacobsen EL, Zhai J, Gallego-Bartolome J, Wang L, Egertsdotter U, Street NR, Jacobsen S, Wang H. DNA methylome of the 20-gigabase Norway spruce genome. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8106-E8113. PMID: 27911846.
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    17. Li S, Yen L, Pastor WA, Johnston JB, Du J, Shew CJ, Liu W, Ho J, Stender B, Clark AT, Burlingame AL, Daxinger L, Patel DJ, Jacobsen S. Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):E5108-16. PMID: 27528681.
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    18. Bewick AJ, Ji L, Niederhuth CE, Willing EM, Hofmeister BT, Shi X, Wang L, Lu Z, Rohr NA, Hartwig B, Kiefer C, Deal RB, Schmutz J, Grimwood J, Stroud H, Jacobsen S, Schneeberger K, Zhang X, Schmitz RJ. On the origin and evolutionary consequences of gene body DNA methylation. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):9111-6. PMID: 27457936; PMCID: PMC4987809 [Available on 02/09/17].
    19. Groth M, Moissiard G, Wirtz M, Wang H, Garcia-Salinas C, Ramos-Parra PA, Bischof S, Feng S, Cokus SJ, John A, Smith DC, Zhai J, Hale CJ, Long JA, Hell R, Díaz de la Garza RI, Jacobsen S. MTHFD1 controls DNA methylation in Arabidopsis. Nat Commun. 2016 Jun 13; 7:11640. PMID: 27291711; PMCID: PMC4909953.
    20. Hale CJ, Potok ME, Lopez J, Do T, Liu A, Gallego-Bartolome J, Michaels SD, Jacobsen S. Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana. PLoS Genet. 2016 06; 12(6):e1006092. PMID: 27253878; PMCID: PMC4890748.
    21. Harris CJ, Husmann D, Liu W, Kasmi FE, Wang H, Papikian A, Pastor WA, Moissiard G, Vashisht AA, Dangl JL, Wohlschlegel JA, Jacobsen S. Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes. PLoS Genet. 2016 May; 12(5):e1005998. PMID: 27171361; PMCID: PMC4865129.
    22. Li S, Yang Z, Du X, Liu R, Wilkinson AW, Gozani O, Jacobsen S, Patel DJ, Du J. Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette. Structure. 2016 Mar 01; 24(3):486-94. PMID: 26876097; PMCID: PMC4775424 [Available on 03/01/17].
    23. Pastor WA, Chen D, Liu W, Kim R, Sahakyan A, Lukianchikov A, Plath K, Jacobsen S, Clark AT. Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. Cell Stem Cell. 2016 Mar 03; 18(3):323-329. PMID: 26853856; PMCID: PMC4779431 [Available on 03/03/17].
    24. Wang H, Beyene G, Zhai J, Feng S, Fahlgren N, Taylor NJ, Bart R, Carrington JC, Jacobsen S, Ausin I. CG gene body DNA methylation changes and evolution of duplicated genes in cassava. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13729-34. PMID: 26483493; PMCID: PMC4640745.
    25. Zhai J, Bischof S, Wang H, Feng S, Lee TF, Teng C, Chen X, Park SY, Liu L, Gallego-Bartolome J, Liu W, Henderson IR, Meyers BC, Ausin I, Jacobsen S. A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis. Cell. 2015 Oct 08; 163(2):445-55. PMID: 26451488; PMCID: PMC5023148 [Available on 10/08/16].
    26. Du J, Johnson LM, Jacobsen S, Patel DJ. DNA methylation pathways and their crosstalk with histone methylation. Nat Rev Mol Cell Biol. 2015 Sep; 16(9):519-32. PMID: 26296162; PMCID: PMC4672940.
    27. Yazdi PG, Pedersen BA, Taylor JF, Khattab OS, Chen YH, Chen Y, Jacobsen S, Wang PH. Increasing Nucleosome Occupancy Is Correlated with an Increasing Mutation Rate so Long as DNA Repair Machinery Is Intact. PLoS One. 2015; 10(8):e0136574. PMID: 26308346; PMCID: PMC4550472.
    28. Yazdi PG, Pedersen BA, Taylor JF, Khattab OS, Chen YH, Chen Y, Jacobsen S, Wang PH. Nucleosome Organization in Human Embryonic Stem Cells. PLoS One. 2015; 10(8):e0136314. PMID: 26305225.
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    29. Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen S. Erratum: MORC1 represses transposable elements in the mouse male germline. Nat Commun. 2015 Jul 10; 6:7604. PMID: 26159654.
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    30. Zhang S, Zhou B, Kang Y, Cui X, Liu A, Deleris A, Greenberg MV, Cui X, Qiu Q, Lu F, Wohlschlegel JA, Jacobsen S, Cao X. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov. 2015; 1. PMID: 26617990.
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    31. Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen S, Pellegrini M. In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife. 2015 Apr 07; 4:e06205. PMID: 25848745; PMCID: PMC4412109.
    32. Zhong X, Hale CJ, Nguyen M, Ausin I, Groth M, Hetzel J, Vashisht AA, Henderson IR, Wohlschlegel JA, Jacobsen S. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):911-6. PMID: 25561521; PMCID: PMC4311829.
    33. Song XJ, Kuroha T, Ayano M, Furuta T, Nagai K, Komeda N, Segami S, Miura K, Ogawa D, Kamura T, Suzuki T, Higashiyama T, Yamasaki M, Mori H, Inukai Y, Wu J, Kitano H, Sakakibara H, Jacobsen S, Ashikari M. Rare allele of a previously unidentified histone H4 acetyltransferase enhances grain weight, yield, and plant biomass in rice. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):76-81. PMID: 25535376; PMCID: PMC4291654.
    34. Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen S. MORC1 represses transposable elements in the mouse male germline. Nat Commun. 2014 Dec 12; 5:5795. PMID: 25503965; PMCID: PMC4268658.
    35. Groth M, Stroud H, Feng S, Greenberg MV, Vashisht AA, Wohlschlegel JA, Jacobsen S, Ausin I. SNF2 chromatin remodeler-family proteins FRG1 and -2 are required for RNA-directed DNA methylation. Proc Natl Acad Sci U S A. 2014 Dec 09; 111(49):17666-71. PMID: 25425661; PMCID: PMC4267348.
    36. Feng S, Cokus SJ, Schubert V, Zhai J, Pellegrini M, Jacobsen S. Genome-wide Hi-C analyses in wild-type and mutants reveal high-resolution chromatin interactions in Arabidopsis. Mol Cell. 2014 Sep 04; 55(5):694-707. PMID: 25132175; PMCID: PMC4347903.
    37. Tsagaratou A, Äijö T, Lio CW, Yue X, Huang Y, Jacobsen S, Lähdesmäki H, Rao A. Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3306-15. PMID: 25071199; PMCID: PMC4136618.
    38. Du J, Johnson LM, Groth M, Feng S, Hale CJ, Li S, Vashisht AA, Wohlschlegel JA, Patel DJ, Jacobsen S. Mechanism of DNA methylation-directed histone methylation by KRYPTONITE. Mol Cell. 2014 Aug 07; 55(3):495-504. PMID: 25018018; PMCID: PMC4127122.
    39. Yelagandula R, Stroud H, Holec S, Zhou K, Feng S, Zhong X, Muthurajan UM, Nie X, Kawashima T, Groth M, Luger K, Jacobsen S, Berger F. The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis. Cell. 2014 Jul 03; 158(1):98-109. PMID: 24995981; PMCID: PMC4671829.
    40. Sequeira-Mendes J, Aragüez I, Peiró R, Mendez-Giraldez R, Zhang X, Jacobsen S, Bastolla U, Gutierrez C. The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin States. Plant Cell. 2014 Jun; 26(6):2351-2366. PMID: 24934173.
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    41. Zhong X, Du J, Hale CJ, Gallego-Bartolome J, Feng S, Vashisht AA, Chory J, Wohlschlegel JA, Patel DJ, Jacobsen S. Molecular mechanism of action of plant DRM de novo DNA methyltransferases. Cell. 2014 May 22; 157(5):1050-60. PMID: 24855943; PMCID: PMC4123750.
    42. Moissiard G, Bischof S, Husmann D, Pastor WA, Hale CJ, Yen L, Stroud H, Papikian A, Vashisht AA, Wohlschlegel JA, Jacobsen S. Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Proc Natl Acad Sci U S A. 2014 May 20; 111(20):7474-9. PMID: 24799676; PMCID: PMC4034193.
    43. Johnson LM, Du J, Hale CJ, Bischof S, Feng S, Chodavarapu RK, Zhong X, Marson G, Pellegrini M, Segal DJ, Patel DJ, Jacobsen S. SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation. Nature. 2014 03 06; 507(7490):124-128. PMID: 24463519; PMCID: PMC3963826.
    44. Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen S, Peters B, Rao A. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1361-6. PMID: 24474761; PMCID: PMC3910590.
    45. Stroud H, Do T, Du J, Zhong X, Feng S, Johnson L, Patel DJ, Jacobsen S. Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis. Nat Struct Mol Biol. 2014 Jan; 21(1):64-72. PMID: 24336224; PMCID: PMC4103798.
    46. Greenberg MV, Deleris A, Hale CJ, Liu A, Feng S, Jacobsen S. Interplay between active chromatin marks and RNA-directed DNA methylation in Arabidopsis thaliana. PLoS Genet. 2013 Nov; 9(11):e1003946. PMID: 24244201; PMCID: PMC3820799.
    47. Widman N, Feng S, Jacobsen S, Pellegrini M. Epigenetic differences between shoots and roots in Arabidopsis reveals tissue-specific regulation. Epigenetics. 2014 Feb; 9(2):236-42. PMID: 24169618; PMCID: PMC3962533.
    48. Li-Byarlay H, Li Y, Stroud H, Feng S, Newman TC, Kaneda M, Hou KK, Worley KC, Elsik CG, Wickline SA, Jacobsen S, Ma J, Robinson GE. RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12750-5. PMID: 23852726; PMCID: PMC3732956.
    49. Chen PY, Ganguly A, Rubbi L, Orozco LD, Morselli M, Ashraf D, Jaroszewicz A, Feng S, Jacobsen S, Nakano A, Devaskar SU, Pellegrini M. Intrauterine calorie restriction affects placental DNA methylation and gene expression. Physiol Genomics. 2013 Jul 15; 45(14):565-76. PMID: 23695884; PMCID: PMC3727019.
    50. Law JA, Du J, Hale CJ, Feng S, Krajewski K, Palanca AM, Strahl BD, Patel DJ, Jacobsen S. Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1. Nature. 2013 Jun 20; 498(7454):385-9. PMID: 23636332; PMCID: PMC4119789.
    51. Stroud H, Ding B, Simon SA, Feng S, Bellizzi M, Pellegrini M, Wang GL, Meyers BC, Jacobsen S. Plants regenerated from tissue culture contain stable epigenome changes in rice. Elife. 2013 Mar 19; 2:e00354. PMID: 23539454; PMCID: PMC3601819.
    52. Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen S, Pellegrini M, Clark AT. Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 2013 Apr 04; 12(4):470-8. PMID: 23415914; PMCID: PMC3684274.
    53. Xu Y, Wang Y, Stroud H, Gu X, Sun B, Gan ES, Ng KH, Jacobsen S, He Y, Ito T. A matrix protein silences transposons and repeats through interaction with retinoblastoma-associated proteins. Curr Biol. 2013 Feb 18; 23(4):345-50. PMID: 23394836.
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    54. Stroud H, Greenberg MV, Feng S, Bernatavichute YV, Jacobsen S. Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome. Cell. 2013 Jan 17; 152(1-2):352-64. PMID: 23313553; PMCID: PMC3597350.
    55. Deleris A, Stroud H, Bernatavichute Y, Johnson E, Klein G, Schubert D, Jacobsen S. Loss of the DNA methyltransferase MET1 Induces H3K9 hypermethylation at PcG target genes and redistribution of H3K27 trimethylation to transposons in Arabidopsis thaliana. PLoS Genet. 2012; 8(11):e1003062. PMID: 23209430; PMCID: PMC3510029.
    56. Caro E, Stroud H, Greenberg MV, Bernatavichute YV, Feng S, Groth M, Vashisht AA, Wohlschlegel J, Jacobsen S. The SET-domain protein SUVR5 mediates H3K9me2 deposition and silencing at stimulus response genes in a DNA methylation-independent manner. PLoS Genet. 2012; 8(10):e1002995. PMID: 23071452; PMCID: PMC3469426.
    57. Du J, Zhong X, Bernatavichute YV, Stroud H, Feng S, Caro E, Vashisht AA, Terragni J, Chin HG, Tu A, Hetzel J, Wohlschlegel JA, Pradhan S, Patel DJ, Jacobsen S. Dual binding of chromomethylase domains to H3K9me2-containing nucleosomes directs DNA methylation in plants. Cell. 2012 Sep 28; 151(1):167-80. PMID: 23021223; PMCID: PMC3471781.
    58. Colomé-Tatché M, Cortijo S, Wardenaar R, Morgado L, Lahouze B, Sarazin A, Etcheverry M, Martin A, Feng S, Duvernois-Berthet E, Labadie K, Wincker P, Jacobsen S, Jansen RC, Colot V, Johannes F. Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16240-5. PMID: 22988127; PMCID: PMC3479620.
    59. Zhong X, Hale CJ, Law JA, Johnson LM, Feng S, Tu A, Jacobsen S. DDR complex facilitates global association of RNA polymerase V to promoters and evolutionarily young transposons. Nat Struct Mol Biol. 2012 Sep; 19(9):870-5. PMID: 22864289; PMCID: PMC3443314.
    60. Chodavarapu RK, Feng S, Ding B, Simon SA, Lopez D, Jia Y, Wang GL, Meyers BC, Jacobsen S, Pellegrini M. Transcriptome and methylome interactions in rice hybrids. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12040-5. PMID: 22778444; PMCID: PMC3409791.
    61. Stroud H, Hale CJ, Feng S, Caro E, Jacob Y, Michaels SD, Jacobsen S. DNA methyltransferases are required to induce heterochromatic re-replication in Arabidopsis. PLoS Genet. 2012 Jul; 8(7):e1002808. PMID: 22792077; PMCID: PMC3390372.
    62. Talbert PB, Ahmad K, Almouzni G, Ausió J, Berger F, Bhalla PL, Bonner WM, Cande WZ, Chadwick BP, Chan SW, Cross GA, Cui L, Dimitrov SI, Doenecke D, Eirin-López JM, Gorovsky MA, Hake SB, Hamkalo BA, Holec S, Jacobsen S, Kamieniarz K, Khochbin S, Ladurner AG, Landsman D, Latham JA, Loppin B, Malik HS, Marzluff WF, Pehrson JR, Postberg J, Schneider R, Singh MB, Smith MM, Thompson E, Torres-Padilla ME, Tremethick DJ, Turner BM, Waterborg JH, Wollmann H, Yelagandula R, Zhu B, Henikoff S. A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin. 2012 Jun 21; 5:7. PMID: 22650316.
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    63. Ausin I, Greenberg MV, Simanshu DK, Hale CJ, Vashisht AA, Simon SA, Lee TF, Feng S, Española SD, Meyers BC, Wohlschlegel JA, Patel DJ, Jacobsen S. INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis. Proc Natl Acad Sci U S A. 2012 May 29; 109(22):8374-81. PMID: 22592791; PMCID: PMC3365198.
    64. Moissiard G, Cokus SJ, Cary J, Feng S, Billi AC, Stroud H, Husmann D, Zhan Y, Lajoie BR, McCord RP, Hale CJ, Feng W, Michaels SD, Frand AR, Pellegrini M, Dekker J, Kim JK, Jacobsen S. MORC family ATPases required for heterochromatin condensation and gene silencing. Science. 2012 Jun 15; 336(6087):1448-51. PMID: 22555433; PMCID: PMC3376212.
    65. Kinoshita T, Jacobsen S. Opening the door to epigenetics in PCP. Plant Cell Physiol. 2012 May; 53(5):763-5. PMID: 22566217; PMCID: PMC3530370.
    66. Pontvianne F, Blevins T, Chandrasekhara C, Feng W, Stroud H, Jacobsen S, Michaels SD, Pikaard CS. Histone methyltransferases regulating rRNA gene dose and dosage control in Arabidopsis. Genes Dev. 2012 May 01; 26(9):945-57. PMID: 22549957; PMCID: PMC3347792.
    67. Stroud H, Otero S, Desvoyes B, Ramírez-Parra E, Jacobsen S, Gutierrez C. Genome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2012 Apr 03; 109(14):5370-5. PMID: 22431625; PMCID: PMC3325649.
    68. Foret S, Kucharski R, Pellegrini M, Feng S, Jacobsen S, Robinson GE, Maleszka R. DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4968-73. PMID: 22416128; PMCID: PMC3324026.
    69. Hale CJ, Jacobsen S. Plant biology: Equal-parenting policy. Nature. 2012 Jan 22; 482(7383):42-4. PMID: 22266937.
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    70. Ausin I, Greenberg MV, Li CF, Jacobsen S. The splicing factor SR45 affects the RNA-directed DNA methylation pathway in Arabidopsis. Epigenetics. 2012 Jan 01; 7(1):29-33. PMID: 22274613; PMCID: PMC3329499.
    71. Sim JJ, Shi J, Calara F, Rasgon S, Jacobsen S, Kalantar-Zadeh K. Association of plasma renin activity and aldosterone-renin ratio with prevalence of chronic kidney disease: the Kaiser Permanente Southern California cohort. J Hypertens. 2011 Nov; 29(11):2226-35. PMID: 21941205.
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    72. Law JA, Vashisht AA, Wohlschlegel JA, Jacobsen S. SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV. PLoS Genet. 2011 Jul; 7(7):e1002195. PMID: 21811420; PMCID: PMC3141008.
    73. Chen PY, Feng S, Joo JW, Jacobsen S, Pellegrini M. A comparative analysis of DNA methylation across human embryonic stem cell lines. Genome Biol. 2011 Jul 06; 12(7):R62. PMID: 21733148; PMCID: PMC3218824.
    74. Stroud H, Feng S, Morey Kinney S, Pradhan S, Jacobsen S. 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol. 2011 Jun 20; 12(6):R54. PMID: 21689397; PMCID: PMC3218842.
    75. Kinney SM, Chin HG, Vaisvila R, Bitinaite J, Zheng Y, Estève PO, Feng S, Stroud H, Jacobsen S, Pradhan S. Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes. J Biol Chem. 2011 Jul 15; 286(28):24685-93. PMID: 21610077; PMCID: PMC3137044.
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